Living, Caring, Learning - Thinking outside the box to solve care challenges in a rare blood disorder by Hibner Sandra

“…Symptoms of the girl’s disorder were evident from birth and through an emergency use request Sandra and the care team enabled her family to access a treatment that at the time was in clinical trial. Poor venous access meant there was a need to adapt how treatment was administered and she worked with the girl’s parents to ensure that she was treated effectively. …”
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What is the effectiveness of chitosan in promoting the healing of tooth extraction sockets? A systematic review by Fayyad Asawer Ahmed

“…A total of 4 randomized clinical trial studies that fulfilled the inclusion criteria were included in the review. …”
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Developing an Appropriate Digital Hearing Aid for Low-Resource Countries: A Case Study by P. Israsena, S. Isaradisaikul, A. Noymai, S. Boonyanukul, A. Hemakom, C. Chinnarat, N. Navacharoen, S. Lekagul

“…Clinically it had undergone a full clinical trial that employed the outcome measurement protocol adopted from the APHAB, the first time implemented in Thai language. …”
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Synergistic Effect of Adjustments of Elastic Stockings to Maintain Reduction in Leg Volume after Mechanical Lymph Drainage by José Maria Pereira de Godoy, Renata Lopes Pinto, Ana Carolina Pereira de Godoy, Maria de Fátima Guerreiro Godoy

“…Eleven patients with Grade II leg lymphedema, regardless of etiology, were evaluated in a randomized clinical trial. The ages ranged from 47 to 83 years old with a mean of 62.4 years. …”
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Integrating WHO thinking healthy programme for maternal mental health into routine antenatal care in China: a randomized-controlled pilot trial by Anum Nisar, Juan Yin, Jingjun Zhang, Wenli Qi, Jie Yu, Jiaying Li, Xiaomei Li, Atif Rahman

“…It merits a definitive randomized trial to assess its effectiveness and cost-effectiveness across various settings.Clinical Trial RegistrationChiCTR1900028114.…”
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Integrated communication support program for oncologists, caregivers and patients with rapidly progressing advanced cancer to promote patient-centered communication: J-SUPPORT 1904... by Makoto Ueno, Takuhiro Yamaguchi, Tempei Miyaji, Yosuke Uchitomi, Takuji Okusaka, Masafumi Ikeda, Maiko Fujimori, Ayako Sato, Sayaka Jinno, Masato Ozaka, Yukiko Takayama, Yoshiyuki Majima

“…Enrolment period ends 31 July 2020; estimated follow-up date is 31 March 2023.Trial registration number UMIN Clinical Trial Registry (UMIN000033612); pre-results.…”
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Ten days of supplementation with a standardized Boswellia serrata extract attenuates soreness and accelerates recovery after repeated bouts of downhill running in recreationally ac... by Dawna Salter, Himana Yalamanchi, Aiswarya Yalamanchi, Amulya Yalamanchi

“…This study suggests that SBS, a novel, standardized extract derived from the gum resin of B. serrata, improves recovery and reduces soreness following high-impact eccentric exercise.Clinical Trial Registrationhttps://ctri.nic.in/Clinicaltrials/pubview2.php, Clinical Trial Registry of India (CTRI/2019/07/020323).…”
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Mobile-based in-home telerehabilitation compared with in-hospital face-to-face rehabilitation for elderly patients after total hip arthroplasty in China's level 1 trauma center: a... by Yang Zhou, Yiming Lyu, Qiaojie Wang, Yanhong Ma, Lihua Huang, Xin Zhang, Xin Zhang

“…There was no significant difference in primary and secondary outcome measures between the two groups.ConclusionOur results showed the noninferiority of in-home telerehabilitation and advocated its application as a reliable alternative to in-hospital face-to-face rehabilitation for patients who underwent THA.Clinical Trial Registrationhttps://www.chictr.org.cn/, Chinese Clinical Trial Registry (Number: ChiCTR1900025825).…”
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Effects of Electrical Stimulation on Activation of Mirror Neuron Network in Healthy Adults during Motor Execution and Imitation: An fNIRS Study by Yao Cui, Fang Cong, Fu-Biao Huang, Ming Zeng, Jun Wang

“…Our results revealed that ES has potential to increase activation of most MNN brain areas, providing evidence for related rehabilitative interventions and device development. Clinical Trial Registration: This study was registered on the China Clinical Trial Registration Center (identifier: ChiCTR2200064082, registered 26, September 2022, https://www.chictr.org.cn/showproj.html?…”
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Effect of periodontal therapy on endothelial function and serum biomarkers in patients with periodontitis and established cardiovascular disease: a pilot study by Ana Molina, Nagore Ambrosio, María Molina, Eduardo Montero, Leire Virto, David Herrera, Elena Figuero, Mariano Sanz

“…AimTo investigate the effect of periodontal therapy on endothelial function of subjects with periodontitis in stages III or IV and established cardiovascular disease.Materials and methodsA triple-blinded, parallel groups, randomized clinical trial of 6 months duration, on patients with history of coronary heart disease and periodontitis in stages III or IV was performed. …”
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Utilization of donor CLL-1 CAR-T cells for the treatment of relapsed of acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation by Meng Zhang, Meng Zhang, Xiaomei Zhang, Xiaomei Zhang, Jiaxi Wang, Wenyi Lu, Xia Xiao, Hairong Lyu, Xiaoyuan He, Yedi Pu, Juanxia Meng, Cuicui Lyu, Xinping Cao, Mingfeng Zhao, Mingfeng Zhao

“…And adjusting the ratio of CD4+ CAR-T cells and CD8+ CAR-T cells prior to infusion may help mitigate CAR-T cell-related side effects.Clinical trial registrationhttps://www.chictr.org.cn/, identifier ChiCTR2000041054.…”
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Multi-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury by Ren Zhou, Jibao Chen, Yunhan Tang, Chuijin Wei, Ping Yu, Xinmei Ding, Li’ao Zhu, Jiajia Yao, Zengqiang Ouyang, Jing Qiao, Shumin Xiong, Liaoliao Dong, Tong Yin, Haiqing Li, Ye Feng, Lin Cheng

“…Methods We conducted a randomized controlled clinical trial investigating the effects of resistance exercise therapy for incomplete SCI. …”
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Anti‐tumor drug supervision in China from 2010 to 2024: the evolution and prospect of drug review standards by Ling Tang, Yuanyuan Song, Hong Zhang, Ruimin Hao, Xin Tong, Xing Ai, Jun Ma, Zhimin Yang

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5-Aminosalicylic Acid Enemas in the Maintenance of Remission in Distal Ulcerative Colitis and Proctitis by Lloyd R Sutherland, Francois Martin

“…A randomized clinical trial of the efficacy and safety of two different dosages of 5-aminosalicylic acid (5-ASA) enemas was carried out in 29 patients who had documented ulcerative colitis involving up to 50cm of distal colon. …”
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Non-Viral Delivery Systems to Transport Nucleic Acids for Inherited Retinal Disorders by Md Jobair Jony, Ameya Joshi, Alekha Dash, Surabhi Shukla

“…Additionally, this review covers recent clinical trial developments in gene therapy for retinal disorders.…”
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Non-invasive management of severe subcutaneous emphysema in a pediatric asthma exacerbation: a case report and review by Amal H. Aljohani, Hamdi Alsufiani, Ghousia Ahmed

“…Early diagnosis and management can lead to a favorable prognosis and a relatively brief hospital stay. Clinical trial number Not applicable.…”
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The Amelioration of Detrimental Biochemical Anomalies by Supplementing B, C, and E Vitamins in Subjects with Type 2 Diabetes Mellitus May Reduce the Rate of Development of Diabetic... by Subhasish Pramanik, Kaustav Banerjee, Lakshmi Kanta Mondal

“…In this prospective clinical trial, 185 patients with T2DM who received B vitamins, vitamin C, and vitamin E along with antidiabetic medication for five years demonstrated a slower rate of the development of DR and reduced abnormal biochemical mediators like reactive oxygen species (ROS), malondialdehyde (MDA), AGE, and vascular endothelial growth factor (VEGF) compared to 175 T2DM individuals who were treated with only antihyperglycemic drugs.…”
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Pulsed Electromagnetic Field Therapy as a Complementary Alternative for Chronic Pelvic Pain Management in an Interstitial Cystitis/Bladder Pain Syndrome Patient by Tyler L. Overholt, Christina Ross, Robert J. Evans, Stephen J. Walker

“…This case provides support for a formal clinical trial to evaluate the efficacy of pulsed electromagnetic field therapy for the management of chronic pelvic pain in interstitial cystitis/bladder pain syndrome.…”
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Management of Class I and Class II Amalgam Restorations with Localized Defects: Five-Year Results by Javier Martin, Eduardo Fernandez, Juan Estay, Valeria V. Gordan, Ivar Andreas Mjör, Gustavo Moncada

“…This five-year prospective clinical trial evaluated amalgam restorations with localized defects that were treated by means of repair or refurbishing. …”
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An Alternative Sensitivity Approach for Longitudinal Analysis with Dropout by Amal Almohisen, Robin Henderson, Arwa M. Alshingiti

“…We apply the local misspecification and least false methods to estimate the bias and sensitivity of parameter estimates for a clinical trial example.…”
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