Spirituality-based palliative care education on quality of life, death anxiety, and resilience of heart failure patients: Randomized controlled clinical trial by Roghayeh Balaghi Inaloo, Mostafa Bijani, Leila Nikrouz, Azizallah Dehghan, Abdulhakim Alkamel, Ali Taghinezhad, Zahra Khiyali

“…Methods: This investigation employed a randomized controlled clinical trial design without blinding, incorporating both experimental and control groups. 80 patients who were randomly assigned to intervention and control groups (40 patients per group). …”
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Erratum: A randomized double-blind active-controlled clinical trial on the efficacy of topical basil (Ocimum basilicum) oil in knee osteoarthritis by Frontiers Production Office

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CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trialsResearch in context by Jan Rekowski, Christina Guo, Olga Solovyeva, Munyaradzi Dimairo, Mahtab Rouhifard, Dhrusti Patel, Emily Alger, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Johann de Bono, Thomas R. Jeffry Evans, Elizabeth Garrett–Mayer, Robert M. Golub, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Israel Maia, Adrian Mander, Lynley V. Marshall, James Matcham, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Lesley Seymour, Yoshiya Tanaka, Moreno Ursino, Christopher J. Weir, Christina Yap

“…Funding: This work is a further extension of the CONSORT-DEFINE study, which was funded by the UK Medical Research Council (MRC)-National Institute for Health and Care Research (NIHR) Methodology Research Programme (MR/T044934/1). The Clinical Trials and Statistics Unit at The Institute of Cancer Research (ICR-CTSU) receives programmatic infrastructure funding from Cancer Research UK (C1491/A25351; CTUQQR-Dec 22/100 004), which has contributed to accelerating the advancement and successful completion of this work.…”
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The Safety and Efficacy of Lansoprazole plus Metoclopramide among Neonates with Gastroesophageal Reflux Disease Resistant to Conservative Therapy and Monotherapy: A Clinical Trial by Peymaneh Alizadeh Taheri, Elahe Validad, Kambiz Eftekhari

“…This study was a randomized clinical trial of term neonates with GERD diagnosis (according to the final version of the I-GERQ-R), resistant to conservative and monotherapy admitted to Bahrami Children Hospital during 2017-2019. …”
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Randomized clinical trial of ICECaP (Individualized Coordination and Empowerment for Care Partners of Persons with Dementia): Primary mental health and burden outcomes. by Virginia T Gallagher, Anna Arp, Ryan Thompson, M Agustina Rossetti, James Patrie, Shannon E Reilly, Carol Manning

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The Effect of Medium Chain Triglycerides on Time to Nutritional Ketosis and Symptoms of Keto-Induction in Healthy Adults: A Randomised Controlled Clinical Trial by Cliff J. d C. Harvey, Grant M. Schofield, Micalla Williden, Joseph A. McQuillan

“…The trial was registered by the Australia New Zealand Clinical Trial Registry ACTRN12616001099415.…”
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Effects of a Multispecies Probiotic Mixture on Glycemic Control and Inflammatory Status in Women with Gestational Diabetes: A Randomized Controlled Clinical Trial by Sadegh Jafarnejad, Sadaf Saremi, Farzan Jafarnejad, Arman Arab

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Clinical Trial of Human Fetal Brain-Derived Neural Stem/Progenitor Cell Transplantation in Patients with Traumatic Cervical Spinal Cord Injury by Ji Cheol Shin, Keung Nyun Kim, Jeehyun Yoo, Il-Sun Kim, Seokhwan Yun, Hyejin Lee, Kwangsoo Jung, Kyujin Hwang, Miri Kim, Il-Shin Lee, Jeong Eun Shin, Kook In Park

“…In a phase I/IIa open-label and nonrandomized controlled clinical trial, we sought to assess the safety and neurological effects of human neural stem/progenitor cells (hNSPCs) transplanted into the injured cord after traumatic cervical spinal cord injury (SCI). …”
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Comparing Health Promotion Programs in Public Dental Service of Vantaa, Finland: A Clinical Trial in 6–36-Month-Old Children by Irma Arpalahti, Mimmi Tolvanen, Kaisu Pienihakkinen

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Insights From Diverse Perspectives on Social Media Messages to Inform Young Adults With Cancer About Clinical Trials: Focus Group Study by Melissa P Beauchemin, Desiree Walker, Allison Rosen, Maria Frazer, Meital Eisenberger, Rhea K Khurana, Edward Bentlyewski, Victoria Fedorko, Corey H Basch, Grace C Hillyer

“…ResultsWe confirmed the previously proposed thematic barriers regarding YA CTE and identified 9 subthemes: awareness, lack of clear and accessible CTE information, fear of the unknown, assumptions about costs, insurance coverage, navigating financial responsibilities, clinical trial discussions, clinical trial misconceptions, and desire for a support network. …”
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Association between white blood cell count and coronary artery bypass graft failure: an individual patient data analysis of clinical trials by Kevin R. An, Sigrid Sandner, Joyce Peper, Yanzai Zhou, Jurrien M. ten Berg, Lamia Harik, Yunpeng Zhu, Laura M. Willemsen, Qiang Zhao, Björn Redfors, Subodh Verma, Mario F. L. Gaudino

“…Conclusion In this pooled analysis of individual patient data from two randomized clinical trials, WBC count was not associated with graft failure after CABG. …”
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Visual, clinical and quality of life outcomes of a new multifocal IOL with optimized diffractive grating: a non-randomized clinical trial by João Marcelo de Almeida Gusmão Lyra, Mariana Silva Gois de Almeida, Lucila de Albuquerque Barbosa Lira, Laís Oliveira dos Santos, Mateus Lins dos Santos, Jorge Artur Peçanha de Miranda Coelho

“…Trial Registration This trial was registered at the ReBEC (Registro Brasileiro de Ensaios Clínicos – Brazilian Registry of Clinical Trials)database under the registration code RBR-772s6y at April 6th, 2020.…”
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Therapy of Inflammatory Bowel Disease using 5-Aminosalicylic Acid, 4-Aminosalicylic Acid and Olsalazine Retention Enemas: Review of Clinical Trials by M. Campieri, P. Gionchetti, A. Belluzzi, C. Brignola, P. Iannone, M. Miglioli, L. Barbara

“…The knowledge that 5-aminosalicylic acid (5-ASA) is the active compound of sulphasalazine and that it acts topically has stimulated the use of 5-ASA containing enemas and ocher similar compounds such as olsalazine and 4-aminosalicylic acid (4-ASA). 5-ASA enemas have been shown to be effective in controlling active disease in clinical trials and have also been shown to be of benefit in prevention of relapses. …”
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Comparison of the Effects of Articaine and Lidocaine Anesthetics on Blood Pressure after Maxillary Infiltration Technique: A Triple-Blind Randomized Clinical Trial by Amirhossein Moaddabi, Parisa Soltani, Maryam Zamanzadeh, Kamran Nosrati, Mojtaba Mollamirzaei, Mariangela Cernera, Gianrico Spagnuolo

“…In this randomized clinical trial, 102 patients were randomly assigned into two groups. …”
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Effect of Local Warm Compression on Restless Leg Syndrome and Fatigue among Critical Care Nurses: A Parallel Randomized Clinical Trial by Maryam Ameri, Hossein Ebrahimi, Ahmad Khosravi, Seyedmohammad Mirhosseini, Mohammad Reza Khatibi

“…This parallel randomized clinical trial was conducted on 120 CCNs in Shahroud by the census sampling method. …”
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Clinical Comparison of MEBO and Hyaluronic Acid Gel in the Management of Pain after Free Gingival Graft Harvesting: A Randomized Clinical Trial by Ahmed Hassan, Enji Ahmed, Dalia Ghalwash, Azza Ezz Elarab

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Effects of functional strength training on pain, function, and lower extremity biomechanics in patients with patellofemoral pain syndrome: a randomized clinical trial by Zheyu Xiong, Wei Zheng, Haiwen Wang, Yuan Gao, Chengshuo Wang

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Coronectomy versus total odontectomy of impacted lower third molars with close relation tothe inferior alveolar canal: An open clinical trial. by Hundren Muhammad, Rozh Mumtaz, Dilman Najmaddin, Omed Ikram

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Effectiveness of nefopam-dexamethasone versus pethidine-dexamethasone for postoperative pain management in cesarean sections: a double-blind, prospective clinical trial by Julian Ojebo, Joseph Achi, Ifeanyichukwu Michael Chukwu, Osadebamen Mercy Oboh, Benedict Ezeife, Aisha Sanusi Muazu, Christian Osemudiamen Igibah, Salami Ezekiel Kelvin

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Macrophages Phenotype Regulated by IL-6 Are Associated with the Prognosis of Platinum-Resistant Serous Ovarian Cancer: Integrated Analysis of Clinical Trial and Omics by Xiaoqing Wu, Wenping Lu, Chaojie Xu, Cuihong Jiang, Zhili Zhuo, Ruipeng Wang, Dongni Zhang, Yongjia Cui, Lei Chang, Xi Zuo, Ya’nan Wang, Heting Mei, Weixuan Zhang, Mengfan Zhang, Chen Li

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