Effect of endoscopic sinus surgery on eustachian tube function in adult patients with chronic rhinosinusitis by Mahmoud Atef Abdelghaffar Youssef, Nassim Talaat Nassim, MohamedNourEddin Bashir Alkeeb, Tareq Muhammad Algarf

“…Method This non-randomized clinical trial study was conducted at the Otorhinolaryngology department, the Faculty of Medicine, Cairo University, on 40 patients > 18 years old, suffering from CRS with or without sinonasal polyposis who are indicated for endoscopic sinus surgery (ESS) and were recruited from Otorhinolaryngology department’s outpatient clinic in the period from November 2022 to June 2023. …”
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Extracellular Vesicles Released from Neprilysin Gene-Modified Human Umbilical Cord-Derived Mesenchymal Stem Cell Enhance Therapeutic Effects in an Alzheimer’s Disease Animal Model... by HyeJu Jeong, Ok Joon Kim, Seung-Hun Oh, Sanghoon Lee, Han A. Reum Lee, Kee Ook Lee, Boo-Yong Lee, Nam Keun Kim

“…Alzheimer’s disease (AD) animal studies have reported that mesenchymal stem cells (MSCs) have therapeutic effects; however, clinical trial results are controversial. Neprilysin (NEP) is the main cleavage enzyme of β-amyloid (Aβ), which plays a major role in the pathology and etiology of AD. …”
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Surgical techniques and prognostic nomogram for patients with supravalvular aortic stenosis by Yuekun Sun, Lizhi Lv, Xinyue Lang, Aihua Zhi, Simeng Zhang, Cheng Wang, Qiang Wang

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Metaverse Clinic for Pregnant Women With Subclinical Hypothyroidism: Prospective Randomized Study by Yuanyuan Zheng, Yizhen Chen, Yan Chen, Liang Lin, Ting Xue, Chuhui Chen, Junping Wen, Wei Lin, Gang Chen

“…Trial RegistrationChinese Clinical Trial Registry ChiCTR2300076803; https://www.chictr.org.cn/showproj.html?…”
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Antimicrobial resistance, virulence gene profiling, and genetic diversity of multidrug-resistant Pseudomonas aeruginosa isolates in Mazandaran, Iran by Ghazaleh Elahi, Hamid Reza Goli, Morvarid Shafiei, Vajihe Sadat Nikbin, Mehrdad Gholami

“…The substantial genetic diversity observed among isolates suggests that P. aeruginosa in this region may rapidly evolve, necessitating ongoing surveillance and more targeted antimicrobial strategies. Clinical trial number Not applicable.…”
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Analysis of antimicrobial resistance and clinical features of Staphylococcus aureus-infected bone and joint infections in children by Xingguang Chen, Ting Zhuang, Chengda Zou, Yao Liu, Qian Sun, Mengxia Li, Wen Zheng, Chaochen Zhao, Xiaodong Wang

“…Further studies are required to validate these findings before they can be widely applied. Clinical trial number Not applicable.…”
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Translation of a Diabetes Remission Service into Australian Primary Care: Findings from the Evaluation of DiRECT-Australia by Ritesh Chimoriya, Kimberly Mitlehner, Chee L. Khoo, Uchechukwu Levi Osuagwu, Russell Thomson, Lei Si, Michael Lean, David Simmons, Milan K. Piya

“…The Diabetes Remission Clinical Trial (DiRECT) study demonstrated that an intensive and structured weight management program in UK primary care resulted in high rates of diabetes remission in adults with recent onset type 2 diabetes mellitus (T2DM). …”
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Preliminary efficacy of eye movement desensitization and reprocessing for children aged 1.5–8 years with PTSD: a multiple baseline experimental design (N = 19) by Carlijn de Roos, Julia Offermans, Samantha Bouwmeester, Ramón Lindauer, Frederike Scheper

“…Further trials are warranted.Trial Registration: International Clinical Trial Registry Platform (before National Trial Register, trial search/who/int: identifier: NL8426, EMDR for young children with PTSD).…”
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Relationship between meteorological factors and the incidence of severe fever with thrombocytopenia syndrome: a systematic review and meta-analysis by Guangju Mo, Hongmei Zhu, Jing Li, Huaiping Zhu, Qiyong Liu

“…Future studies on the relationship between meteorological factors and the incidence of SFTS should fully consider human activities and environmental factors, and explore the pathogenesis and transmission mechanisms in greater depth, so as to provide targeted preventive measures. Clinical trial number Not applicable.…”
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Intranasal Insulin Diminishes Postoperative Delirium and Elevated Osteocalcin and Brain Derived Neurotrophic Factor in Older Patients Undergoing Joint Replacement: A Randomized, Do... by Yang M, Zhou L, Long G, Liu X, Ouyang W, Xie C, He X

“…Intranasal insulin administration reduced the HOMA-IR on D3 (P=0.002).Conclusion: Intranasal insulin notably reduced the incidence and severity of POD in older patients undergoing joint replacement, which may be related to the elevation in osteocalcin and BDNF levels.Trial Registry Numbers: Chinese Clinical Trial Registry (ChiCTR2300068073).Keywords: intranasal insulin, osteocalcin, postoperative delirium, brain derived neurotrophic factor, older patient…”
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The Effect of the Teach-Back Method on Knowledge, Performance, Readmission, and Quality of Life in Heart Failure Patients by Ali Rahmani, Amir Vahedian-Azimi, Masoud Sirati-Nir, Reza Norouzadeh, Hamid Rozdar, Amirhossein Sahebkar

“…This study aimed to determine the effect of the teach-back method on knowledge, performance, readmission, and quality of life in these patients. Methods. This clinical trial was conducted in patients with heart failure (n = 70) hospitalized in the internal wards of the Baqiyatallah al-Azam Medical Center in Tehran (2019). …”
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Significance of Semiquantitative Assessment of Preformed Donor-Specific Antibody Using Luminex Single Bead Assay in Living Related Liver Transplantation by Atsushi Yoshizawa, Hiroto Egawa, Kimiko Yurugi, Rie Hishida, Hiroaki Tsuji, Eiji Ashihara, Aya Miyagawa-Hayashino, Satoshi Teramukai, Taira Maekawa, Hironori Haga, Sinji Uemoto

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Risk Factors for Postoperative Nausea and Vomiting After TACE: A Prospective Cohort Study by Yuzhu Wang, Xin Zhou, Guoping Li, Qianzhou Lv, Xiaoyu Li, Zhiping Yan

“…The receiver operating characteristic (ROC) curve was plotted to assess the regression model. The clinical trial number did not apply in the study. <b>Results:</b> In this study, 212 out of a total of 904 patients with HCC undergoing TACE during their hospital stay were included for analysis. …”
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Jackknife versus Lithotomy Position for Hemorrhoidectomy Surgery: A Randomized Controlled Trial by Sina Ghasemi, Behzad Imani, Alireza Jafarkhani, Ashkan Karimi, Ali Yamini

“…Materials and Methods: The present study was a clinical trial conducted on 60 patients with hemorrhoids at Besat Hospital in Hamedan. …”
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The effect of continuous positive airway pressure (CPAP) application on airway problems in pediatric patients with subglottic stenosis who undergo balloon dilatation by Zeliha Tuncel, Şenay Göksu, Özlem Deligöz, Kemal Tolga Saracoglu, Abdulatif Albasha, Bushra M. Abdallah, Ayten Saracoglu

“…Trial registration The protocol for this clinical trial was retrospectively registered on clinicaltrials.gov with registration ID NCT06183515 on 30 November 2023.…”
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Activities of daily living after surgery among older patients with gastrointestinal and hepatobiliary-pancreatic cancers: a retrospective observational study using nationwide healt... by Ayako Okuyama, Takahiro Higashi, Hisashi Kosaka, Asao Ogawa, Masaki Kaibori

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Acupuncture and Kinesitherapy Improve Physical Activity More than Kinesitherapy Alone in Patients with Acute Decompensated Chronic Heart Failure with Reduced Ejection Fraction Who... by Dejan Ilic, Zoran Jovic, Zorica Mladenovic, Vesna Pejovic, Branislava Lung, Aleksandra Kozic, Slobodan Obradovic

“…<b>Methods</b>: A prospective, sham-procedure-controlled, double-blind, randomized clinical trial with three patient groups was conducted. …”
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Comprehensive analysis of vaginal microbiota in Chinese women with genital tuberculosis: implications for diagnosis and treatment by Zhan Zhang, Xiaonan Zong, Zhaohui Liu, Xiaoyu Dong, Huihui Bai, Linyuan Fan, Ting Li

“…Given the effect of antibiotics on vaginal flora, probiotic combined interventions could be used as a future research direction. Clinical trial number Not applicable.…”
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Comparative evaluation of allograft particulate bone and cortical bone blocks combined with xenograft bone for labial bone defects in the aesthetic zone: a prospective cohort study by Li-Rong Huang, Yong-Jin Zhong, Xiao-Qing Zhang, Ze-Ru Feng, Yan-Cheng Lai, Hong-Kun Wu, An-Chun Mo

“…Trial registration The study was retrospectively registered in the Chinese Clinical Trial Registry ( http://www.chictr.org.cn/ ) with the registration number ChiCTR2300070538 on April 14, 2023.…”
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Motivational interviewing to improve self‐care in heart failure patients (MOTIVATE‐HF): a randomized controlled trial by Ercole Vellone, Paola Rebora, Davide Ausili, Valentina Zeffiro, Gianluca Pucciarelli, Gabriele Caggianelli, Stefano Masci, Rosaria Alvaro, Barbara Riegel

“…Including caregivers may potentiate the effect, especially in self‐care management. ClinicalTrial.gov, identifier: NCT02894502.…”
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