Prediction of Multiple Organ Failure Complicated by Moderately Severe or Severe Acute Pancreatitis Based on Machine Learning: A Multicenter Cohort Study by Fumin Xu, Xiao Chen, Chenwenya Li, Jing Liu, Qiu Qiu, Mi He, Jingjing Xiao, Zhihui Liu, Bingjun Ji, Dongfeng Chen, Kaijun Liu

“…The study is registered with the China Clinical Trial Registry (Identifier: ChiCTR1800016079).…”
Get full text

Functional and structural connectivity of the subregions of the amygdala in ADHD children with or without ODD by Zhao-Min Wu, Peng Wang, Xue-Chun Liu, Qing-Chao Zhou, Xiao-Lan Cao, Li Sun, Lu Liu, Qing-Jiu Cao, Li Yang, Yu-Feng Wang, Ying Qian, Bin-Rang Yang

“…Conclusions Altered structural and functional connectivity of the subregions of the amygdala in children with ADHD compared with their healthy counterparts were respectively associated with ADHD-related behavioral and emotional problems. Clinical trial number : not applicable.…”
Get full text

An investigator-blinded, 24-month, parallel-group, non-inferiority study to compare aesthetic restorations in primary anterior teeth in a paediatric dental clinic: study protocol f... by Ana Paula Taboada Sobral, Elaine Marcilio Santos, Marcela Leticia Leal Gonçalves, Lara Jansiski Motta, Anna Carolina Ratto Tempestini Horliana, Sandra Kalil Bussadori, Elza Padilha Ferri, Juliana Maria Altavista Sagretti Gallo, Thais Gimenez, José Carlos Pettorossi Imparato

“…Thus, this project aims to evaluate the effectiveness of restorative treatment of anterior primary teeth with monochromatic composite resin in single insertion through polyvinyl crowns, after selective removal of carious tissue compared with the effectiveness of conventional restoration.Methods and analysis This study proposes to conduct a randomised clinical trial, composed of a sample of 194 deciduous central and lateral incisors with active cavitated lesions, simplified International Caries Detection and Assessment System (ICDAS) C+ score (active and extensive stage caries: ICDAS 5 and 6), with involvement of more than two surfaces. …”
Get full text

Congenital muscular dystrophies and myopathies: the leading cause of genetic muscular disorders in eleven Chinese families by Bin Mao, Xiaoling Cai, Na Lin, Yulin Jiang, Na Hao, Yifang Dai, Danhua Guo, Deqin He, Huili Xue, Lingji Chen, Qianqian He, Min Zhang, Meihuan Chen, Hailong Huang, Liangpu Xu

“…Molecular analysis is highly beneficial for the precise diagnosis, genetic counseling and prenatal diagnosis of families suspected of having genetic muscular disorders. Clinical trial number Not applicable.…”
Get full text

Brain Functional Network in Chronic Asymptomatic Carotid Artery Stenosis and Occlusion: Changes and Compensation by Shihao He, Ziqi Liu, Zongsheng Xu, Ran Duan, Li Yuan, Chu Xiao, Zhe Yi, Rong Wang

“…This trial is registered with Clinical Trial Registration-URL http://www.chictr.org.cn and Unique identifier ChiCTR1900023610.…”
Get full text

Intense Pulsed Light Therapy with Optimal Pulse Technology as an Adjunct Therapy for Moderate to Severe Blepharitis-Associated Keratoconjunctivitis by Fang Ruan, Yunxiao Zang, Ruti Sella, Hongshuang Lu, Shang Li, Ke Yang, Tao Jin, Natalie A. Afshari, Zhiqiang Pan, Ying Jie

“…This open-label nonrandomized clinical trial evaluated 33 patients diagnosed with BKC. …”
Get full text

Smartphone video games for cognitive functions and negative symptoms in male with chronic schizophrenia: A randomized controlled trial by Wenhui Wang, Mengting Ye, Yongjie Zhong, Miaomiao Zhang, Yue Wang, Chuanchuan Chen, Yitan Yao, Ziqiao Feng, Xiaoping Yuan, Shenya Shi, Xiaoqin Zhou, Kai Zhang

“…Trial registration: This study was registered in the Chinese Clinical Trial Registry (ChiCTR2100044113) and registered on 11/3/21.…”
Get full text

Impaired Hepatitis B and COVID-19 vaccination responses show strong concordance in hemodialysis patients with end stage renal disease by Karsten Lürken, Anna Meinecke, Luis A. Manthey, Anne Cossmann, Metodi V. Stankov, Frank Klawonn, Anna Zychlinsky Scharff, Sandra Steffens, Alexandra Dopfer-Jablonka, Frank Müller, Georg M. N. Behrens, Christine Happle

“…Trial registration: German Clinical Trial Registry, DRKS00021152.…”
Get full text

Cholesterol, triglycerides, HDL, and nitric oxide as determinants of resting heart rate variability in non-hospitalized mild post-COVID individuals: a cross-sectional study by Lucivalda Viegas de Almeida, Aldair Darlan Santos-de-Araújo, Luís Cláudio Nascimento da Silva, Patricia Martins Santos, Mariana Campos Maia, Victória Pereira Frutuoso, Daniel Santos Rocha, Adriana Sousa Rêgo, Daniela Bassi-Dibai

“…Metabolic outcomes are associated and explain between 16.6% and 30.30% of certain variables of resting HRV in post-COVID individuals. Clinical trial number Not applicable.…”
Get full text

Two Transcutaneous Stimulation Techniques in Shoulder Pain: Transcutaneous Pulsed Radiofrequency (TPRF) versus Transcutaneous Electrical Nerve Stimulation (TENS): A Comparative Pil... by Mu-Lien Lin, Hung-Wei Chiu, Zao-Ming Shih, Po-Ying Lee, Pei-Zhi Li, Chin-Hong Guo, Yuan-Jie Luo, Shen-Chieh Lin, Kwan-Yu Lin, Yu-Ming Hsu, Angela Pang, Weiwu Pang

“…A prospective, randomized, and double-blind clinical trial. Setting. Academic pain service of a city hospital. …”
Get full text

CLINTERVENTIONAL protocol: a randomized controlled trial to evaluate clinical consultations and audiovisual tools for interventional radiology by Pedro Blas García Jurado, Juan José Espejo Herrero, María Sagrario Lombardo Galera, María Eugenia Pérez Montilla, Sara Barranco Acosta, José García-Revillo, Pilar Font Ugalde, Marina Álvarez Benito

“…Key Points We describe the protocol of an interventional radiology randomized clinical trial. The control group will receive procedure information from the referring physician and the experimental group receives additional consultation with interventionalists and views a video. …”
Get full text

Preliminary Experiment on the Effect of 18% Substitute Salt on Home Blood Pressure Variability in Hypertensives by Jing Li, Lisha Mu, Huakun Rao, Yangfeng Wu, Hao Wang, Hongbing Tao, Lihong Mu

“…The present study is a phase I clinical trial involving 43 hypertensives in which the effect of 18% sodium substitute salt on the home blood pressure variability (BPV) was observed for 8 weeks with weekly follow-up. …”
Get full text

TangBi Formula for Painful Diabetic Distal Symmetric Polyneuropathy: A Multicenter, Randomized, Double‐Blind, Placebo‐Controlled and Parallel‐Group Trial by Xuefei Zhao, Xuedong An, Yashan Cui, Liu Dong, Zhaohui Fang, Zhonghua Zheng, Xinhe Zuo, Huailin Gao, Tianshu Gao, Qing Ni, Fengmei Lian, Xiaolin Tong

“…Methods This multicenter, placebo‐controlled, double‐blind, randomized controlled clinical trial recruited patients from 6 clinical centers in mainland China. …”
Get full text

Classification of kinesiophobia in patients after cardiac surgery under extracorporeal circulation in China: latent profile and influencing factors analysis from a cross-sectional... by Qi Li, Rong Wang, Yanmei Gu, Tong Ren, Jing Jing Piao, Wenhui Xing, Yujing Liang

“…These findings provide a basis for implementing preventive interventions in cardiac rehabilitation.Trial registration number The research is registered with the Chinese Clinical Trial Registry (ChiCTR2200057895).…”
Get full text

Factors Influencing the Choice Between Multi-Target Stool DNA and Colonoscopy for Colorectal Cancer Screening Among Alaska Native Peoples by Lauren A. Jeffries, Christie A. Flanagan, Lila J. Finney Rutten, John B. Kisiel, Diana G. Redwood

“…The Alaska Tribal Health System is increasing colorectal cancer (CRC) screening among Alaska Native (AN) peoples, who experience the highest CRC rate in the world. Through a clinical trial (NCT04336397), AN people living in rural/remote Alaska were offered either the previously unavailable multi-target stool DNA test (mt-sDNA; Cologuard^®) or colonoscopy. …”
Get full text

Association between non-alcoholic fatty liver disease and progression of abdominal aortic aneurysm: a multicenter study by Ximing Wang, Jingxiang Sun, Na Chang, Menghan Liu, Shuai Zhang

“…It can improve the diagnostic efficacy of predicting the progression of abdominal aortic aneurysms. Clinical trial number Not applicable. This research is a retrospective analysis.…”
Get full text

The influence of prosthetic treatments and implant-supported prostheses on posterior mandibular ridge atrophy: a retrospective cohort study by Alwin Sokolowski, Sandra Huber, Behrouz Arefnia, Anke Pichler, Martin Lorenzoni, Armin Sokolowski

“…Long-term stability is possible with fixed partial prostheses, RPDs are less favorable in the absence of a distal support and bar-retained overdentures on four or more implants exhibited the lowest bone atrophy in fully edentulous mandibles. Clinical trial number Not applicable – retrospective analysis.…”
Get full text

Evaluating the effectiveness of integrated traditional Chinese and Western treatment based on symptom grading: a study protocol for a multi-center, randomized controlled trial of p... by Jiaxi Mai, Tingwei Zhou, Tingwei Zhou, Tingwei Zhou, Chen Wang, Chen Wang, Junrong Ye, Junrong Ye, Jiao Chen, Jiao Chen, Jiao Chen, Wen Wang, Wen Wang, Wen Wang, Yuanxin Pan, Yuanxin Pan, Yuanxin Pan, Yanheng Wei, Yanheng Wei, Lexin Yuan, Lexin Yuan, Hang Yang, Hang Yang, Shengwei Wu, Shengwei Wu, Jianxiong Guo, Jianxiong Guo, Jianxiong Guo, Aixiang Xiao, Aixiang Xiao, Aixiang Xiao

“…At the end of the study, it is expected for the experimental group to have an improvement in depressive symptoms and sleep quality and an enhancement in mental health awareness.Clinical trial registrationhttp://www.chictr.org.cn, identifier ChiCTR2300075169.…”
Get full text

Auricular acupressure for minimizing adverse reactions to colonoscopic bowel preparation in hospitalized patients: A randomized controlled trial by Jiahui Zhang, Chang Liu, Guodong Ruan, Haiyan Zhang, Beiping Zhang, Xuejun Hu, Cailing Zhong

“…Methods: This was a prospective, assessor-blinded, randomized controlled clinical trial implemented at Guangdong Provincial Hospital of Chinese Medicine. …”
Get full text

Intraocular lens calculation formula selection for short eyes: based on axial length and anterior chamber depth by Ruoxi Gao, Jiaqing Zhang, Xiaotong Han, Yiguo Huang, Ruoxuan Huang, Jinfeng Ye, Ling Wen, Xiaozhang Qiu, Xiaoyun Chen, Xuhua Tan, Lixia Luo

“…Conclusion The Kane formula showed the highest accuracy in short eyes, whereas the Pearl-DGS had superior performance in eyes with a relatively shorter AL and deeper ACD. Clinical trial number Not applicable.…”
Get full text