Metformin Exhibits Anti‐Inflammatory Effects by Regulating microRNA‐451/CXCL16 and B Cell Leukemia/Lymphoma 2 in Patients With Osteoarthritis by Nahid Alimoradi, Amin Ramezani, Mohammad Tahami, Negar Firouzabadi

“…Methods In this double‐blind placebo‐controlled clinical trial, patients were randomly divided into two groups: one receiving metformin and the other receiving a placebo for four months (starting at 0.5 g/day for the first week, increasing to 1 g/day for the second week, and increasing to 1.5 g/day for the remaining period). …”
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The factors influencing self-management in patients with depression: a qualitative research from China by Ying-Li Gao, Lu-Xia Shen, Xiu-Mei Hou, Shu-Ping Si, Huan-Huan Zhu, Zhong-Li Shi

“…Moreover, they should help patients increase their self-efficacy and enhance their self-management abilities through health education and other means. Clinical trial number Not applicable.…”
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A New Hope for the Patients of Non‐Alcoholic Steatohepatitis: FDA Gives Green Signal for Resmetirom Use by Abdul Haseeb Hasan, Muhammad Ali Abid, Muhammad Hafi Abid, Laiba Suhail, Abubakar Nazir

“…Methods This study is a comprehensive literature review analyzing peer‐reviewed articles, clinical trial data, and public health reports. No original analyses were conducted, and no statistical software was utilized in this review. …”
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Perceptions and barriers to the use and training of point-of-care ultrasound among Finnish emergency physicians – a nationwide survey by J. Järvinen, O. Hannula, A. Meuronen, K. Mattila

“…Improvements on training infrastructure, including enhanced mentorship and increased access to ultrasound equipment, are essential enablers of such a reform. Clinical trial registration Not applicable.…”
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Effect of chiropractic care on low back pain for active-duty military members: Mediation through biopsychosocial factors. by Zacariah K Shannon, Cynthia R Long, Elizabeth A Chrischilles, Christine M Goertz, Robert B Wallace, Carri Casteel, Ryan M Carnahan

“…Data from a multi-site, pragmatic clinical trial comparing six weeks of chiropractic care plus usual medical care to usual medical care alone for 750 US active-duty military members with LBP were analyzed using natural-effect, multiple-mediator modeling. …”
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Cost-Effectiveness Analysis for the Treatment of Hyperphosphatemia in Predialysis Patients: Calcium-Based versus Noncalcium-Based Phosphate Binders by B. L. Goh, A. Soraya, A. Goh, K. L. Ang

“…Survival was estimated by using efficacy data from the INDEPENDENT-CKD clinical trial. Cost data was obtained from Malaysian studies while health state utilities were derived from literature. …”
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DA5-CH and Semaglutide Protect against Neurodegeneration and Reduce α-Synuclein Levels in the 6-OHDA Parkinson’s Disease Rat Model by Lingyu Zhang, Chun Li, Zijuan Zhang, Zhenqiang Zhang, Qian-Qian Jin, Lin Li, Christian Hölscher

“…It is in a phase II clinical trial in patients with PD. Two previous phase II trials in PD patients showed good effects with the older GLP-1 receptor agonists, exendin-4 and liraglutide. …”
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Natural bioactive compounds form herbal medicine in Alzheimer’s disease: from the perspective of GSK-3β by Mei Wang, Wendi Huang, Juan Huang, Juan Huang, Yong Luo, Yong Luo, Nanqu Huang, Nanqu Huang

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Staging of esophageal cancer using PET/MRI: a systematic review with head-to-head comparison by Alisa Mohebbi, Saeed Mohammadzadeh, Zahra Moradi, Afshin Mohammadi, Hossein Poustchi, Seyed Mohammad Tavangar

“…Conclusion With protocol adjustments, PET/MRI might be utilized in the future for preoperative staging of esophageal cancer. Clinical trial number N/A.…”
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Effectiveness of Super Floss and Water Flosser in Plaque Removal for Patients Undergoing Orthodontic Treatment: A Randomized Controlled Trial by Nozha Sawan, Afnan Ben Gassem, Faisal Alkhayyal, Aroob Albakri, Nada Al-Muhareb, Eman Alsagob

“…A single-blind, randomized, controlled, parallel clinical trial with a split-mouth protocol was conducted on young adult orthodontic patients who were recruited from Riyadh Specialized Dental Center in Riyadh, Saudi Arabia. …”
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Patients Walking Faster After Anterior Cruciate Ligament Reconstruction Have More Gait Asymmetry by Rachel J. Knobel, Naoaki Ito, Elanna K. Arhos, Jacob J. Capin, Thomas S. Buchanan, Lynn Snyder-Mackler

“… # Study Design Secondary analysis of a clinical trial. # Methods Athletes 24±8 weeks after primary ACLR walked at self-selected speeds as kinematics, kinetics, and electromyography data were collected. …”
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Left Ventricular End-Diastolic Pressure and B-Type Natriuretic Peptide Levels Guidance of Low-Dose Furosemide Treatment to Prevent Contrast-Induced Nephropathy in Patients with Per... by Guoqiang Gu, Demin Liu, Rui Lu, Wei Cui

“…This parallel randomized clinical trial was conducted at a tertiary hospital in China. …”
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Augmentation versus No Augmentation for Immediate Postextraction Implants by Huda Hamed Basher Mohamed, Asma M. Serag Eldien, Amr Zahran

“…We searched the Cochrane Oral Health Group Trial Register, Cochrane Central Register of Controlled Trials, MEDLINE, and the WHO International Clinical Trial Registry Platform (22 March 2017). Two reviewers independently assessed trials for inclusion and risk of bias, extracted data, and checked for accuracy. …”
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The Anterior Chamber Injection of Moxifloxacin Injection to Prevent Endophthalmitis after Cataract Surgery: A Meta-analysis by Xiao-lei Wang, Xiao-yong Huang, Zhen Wang, Wei Sun

“…A computer-based search of PubMed, Embase, the Cochrane Library, and the Clinical Trial database for articles related to anterior intraventricular injection of moxifloxacin for the prevention of endophthalmitis after cataract surgery was performed through April 2019. …”
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Effect of Dexmedetomidine Added to Lidocaine Cartridge on the Level of Patient Sedation, Cooperation, and Patient and Surgeon Satisfaction during Mandibular Third-Molar Extraction... by Milad Etemadi Sh, Nasser Kaviani, Kimia Salimian, Golnaz Tajmiri

“…This trial is registered with the clinical trial registration number: IRCT20200406046966N.…”
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Accuracy of Teledentistry for Diagnosis and Treatment Planning of Pediatric Patients during COVID-19 Pandemic by Ozra Golsanamloo, Sanaz Iranizadeh, Amir Reza Jamei Khosroshahi, Leila Erfanparast, Ali Vafaei, Yalda Ahmadinia, Solmaz Maleki Dizaj

“…This double-blind clinical trial was conducted on 20 children (aged 6 to 12 years) with a chief complaint of dental caries with or without pain. …”
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A randomized controlled trial to compare the effect of oxycodone and sufentanil on postoperative analgesia and immune function for laparoscopic resection of colorectal cancer by Chunmei Lin, Zhiqiao Xu, XinLiang, Hong Wei, Xiaoping Wang

“…Trial registration Chinese Clinical Trial Registry (ChiCTR2400089072).…”
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Recovery process of patients with iliac vein compression syndrome after stenting: a grounded theory study by Yi-Yun Zeng, Wen-Ling Chen, Jimmy Wei Hwa Tan, Shih-Chun Lin, Kuan-Yi Yen, Fan-Hao Chou, Peta-Anne Zimmerman

“…Careful attention should be paid to the importance of clarifying patient expectations after stenting, addressing post-treatment physical discomfort and emotional anxiety issues, and enabling patients to confidently undergo follow-up and rehabilitation to achieve their recovery goals. Clinical trial number Not applicable.…”
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Comparative efficacy of programmed death ligand 1 inhibition and chemotherapy in advanced gastric or gastroesophageal junction cancer with combined positive score – a meta-analysis... by Zakari Shaibu, Fumeng Yang, Liu Ting, Lily Dzidula, Amina Elmi Yusuf, Zhi-hong Chen, Wei Zhu

“…We systematically searched PubMed, Google Scholar, and Web of science for clinical trial studies comparing PD-L1 inhibitors and chemotherapy in CPS-positive patients, focusing on studies published up to 10 April 2023. …”
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Effects of neutrophil granule proteins on sepsis-associated lymphopenia and their relationship with CD4+ T-cell pyroptosis by Jia-yu Mao, Ya-wen Xie, Xian-li Lei, Jia-hui Zhang, Wei Cheng, Na Cui

“…Furthermore, neutrophil granule proteins were significantly correlated with CD4+ T cell and its pyroptosis [MPO and CD4+ T cells (r = −0.4039, p < 0.0001), CD4+NLRP3 (r = 0.4868, p < 0.0001), NE and CD4+ T cells (r = −0.5140, p < 0.0001), and CD4+NLRP3 (r = 0.6513, p < 0.0001)].ConclusionIncreased levels of neutrophil granule proteins were significantly associated with SAL incidence, and a significant relationship between neutrophil granule proteins and the pyroptosis pathway of CD4+ T cells was revealed.Clinical trial registrationchictr.org.cn identifier ChiCTR-ROC-17010750.…”
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