A Systematic Review of the Effectiveness of Core Stability Exercises in Patients with Non-Specific Low Back Pain by Zachary Smrcina, Sarah Woelfel, Christopher Burcal

“… # Study Selection Studies were included if they had patients diagnosed with NSLBP, used CSE as a treatment for NSLBP, and were a clinical trial. Exclusion criteria were studies that did not utilize an objective pain scale, patients who had a specific diagnosed pathology contributing to the NSLBP or received treatment for their NSLBP within the prior six months…”
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Intensive care nurses’ experiences of teamwork during the covid-19 pandemic. a qualitative study. by Jeanette Eckerblad, Åsa Dorell, Helen Conte

“…The adaptability and willingness to find solutions helped nurses regain control, manage the challenges they faced and find new ways to collaborate. Clinical trial number Not applicable.…”
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Appropriate Timing and Type of Physical Training in Patients with COVID-19 for Muscle Health and Quality of Life: A Systematic Review by I. Gusti Putu Suka Aryana, Siti Setiati, Ivana Beatrice Paulus, Dian Daniella

“…Studies were reviewed using critical appraisal by NOS and CEBM. Two clinical trial studies and four observational designs were selected. …”
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Associations of Polyunsaturated Fatty Acid Intake with Bone Mineral Density in Postmenopausal Women by Margaret Harris, Vanessa Farrell, Linda Houtkooper, Scott Going, Timothy Lohman

“…A secondary analysis of cross-sectional data was analyzed from 6 cohorts (Fall 1995–Fall 1997) of postmenopausal women (n=266; 56.6±4.7 years) participating in the Bone Estrogen Strength Training (BEST) study (a 12-month, block-randomized, clinical trial). Bone mineral density (BMD) was measured at femur neck and trochanter, lumbar spine (L2–L4), and total body BMD using dual-energy X-ray absorptiometry (DXA). …”
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Inhibitory Effects of iPSC-MSCs and Their Extracellular Vesicles on the Onset of Sialadenitis in a Mouse Model of Sjögren’s Syndrome by Bo Hai, Taeko Shigemoto-Kuroda, Qingguo Zhao, Ryang Hwa Lee, Fei Liu

“…Systemic infusion of allogeneic mesenchymal stem cells (MSCs) isolated from tissues such as bone marrow (BM) alleviated SS in mouse models and a small clinical trial, but further research and application of this MSC therapy were hindered by limited expandability, significant donor variations, and safety concerns of tissue-derived MSCs. …”
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Attenuation and Immunogenicity of a Live High Pathogenic PRRSV Vaccine Candidate with a 32-Amino Acid Deletion in the nsp2 Protein by Wenhui Lu, Baoli Sun, Jianyue Mo, Xiduo Zeng, Guanqun Zhang, Lianxiang Wang, Qingfeng Zhou, Ling Zhu, Zhili Li, Qingmei Xie, Yinzuo Bi, Jingyun Ma

“…Following PRRSV experimental challenge, pigs inoculated with a single dose of QY1 P100 developed no significant clinic symptoms and well tolerated lethal challenge, while QY1 P80 group still developed mild fever in the clinic trial after challenge. Thus, we concluded that QY1 P100 was a promising and highly attenuated PRRSV vaccine candidate.…”
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Dose-Escalated Hypofractionated Intensity-Modulated Radiotherapy in High-Risk Carcinoma of the Prostate: Outcome and Late Toxicity by David Thomson, Sophie Merrick, Ric Swindell, Joanna Coote, Kay Kelly, Julie Stratford, James Wylie, Richard Cowan, Tony Elliott, John Logue, Ananya Choudhury, Jacqueline Livsey

“…We report 5-year outcome and long-term toxicity data within a phase II clinical trial. Materials and Methods. 60 men with predominantly high-risk prostate cancer were treated. …”
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Sustained Weight Loss with Vagal Nerve Blockade but Not with Sham: 18-Month Results of the ReCharge Trial by Scott A. Shikora, Bruce M. Wolfe, Caroline M. Apovian, Mehran Anvari, David B. Sarwer, Robert D. Gibbons, Sayeed Ikramuddin, Christopher J. Miller, Mark B. Knudson, Katherine S. Tweden, Michael G. Sarr, Charles J. Billington

“…The ReCharge trial is a double-blind, randomized controlled clinical trial of 239 participants with body mass index (BMI) of 40 to 45 kg/m or 35 to 40 kg/m with one or more obesity-related conditions. …”
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Effects of Tocotrienol on Cardiovascular Risk Markers in Patients With Chronic Kidney Disease: A Randomized Controlled Trial by Liana Trugilho, Lívia Alvarenga, Ludmila Cardozo, Bruna Paiva, Jessyca Brito, Isis Barboza, Jonatas Almeida, Juliana dos Anjos, Pramod Khosla, Marcelo Ribeiro-Alves, Denise Mafra

“…This double-blind, placebo-controlled, randomized clinical trial aimed to evaluate the effects of a tocotrienol-rich fraction (TRF) supplementation (300 mg/day) on oxidative stress and inflammatory markers, including transcription factors in nondialysis (ND) and hemodialysis (HD) CKD patients for three months. …”
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Sex-Related Differences in the Effects of the Mediterranean Diet on Glucose and Insulin Homeostasis by Alexandra Bédard, Louise Corneau, Benoît Lamarche, Sylvie Dodin, Simone Lemieux

“…Results suggest that the more favorable changes in glucose/insulin homeostasis observed in men compared to women in response to the MedDiet are not explained by sex differences in NEFA response. This clinical trial is registered with clinicaltrials.gov NCT01293344.…”
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Short-Course Induction Treatment with Intrathecal Amphotericin B Lipid Emulsion for HIV Infected Patients with Cryptococcal Meningitis by Gerardo Alvarez-Uria, Manoranjan Midde, Raghavakalyan Pakam, Pradeep Sukumar Yalla, Praveen Kumar Naik, Raghuprakash Reddy

“…However, the good tolerability of intrathecal administration of AmB lipid emulsion and the clinically important mortality reduction observed with the short-course induction treatment warrant further research, ideally through a randomized clinical trial.…”
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Gum Arabic Reduces C-Reactive Protein in Chronic Kidney Disease Patients without Affecting Urea or Indoxyl Sulfate Levels by Sarra Elamin, Mariam J. Alkhawaja, Amina Y. Bukhamsin, Mohamed A. S. Idris, Muntasir M. Abdelrahman, Nasrulla K. Abutaleb, Abdulrahman A. Housawi

“…This trial is registered with Saudi Clinical Trial Registry number 15011402.…”
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Ultrasound-based abdominal muscles and diaphragm assessment in predicting extubation failure in patients requiring neurointensive care: a single-center observational study by Xiang Qiu, Chuanjuan Chen, Lan Lv, Bihui Yang, Zhiqiang Wang, Jun Ni

“…Trial registration: The study was registered on Chinese Clinical Trial Registry: ChiCTR2400088210, Registered 13 August 2024 - Retrospectively registered, https://www.chictr.org.cn/bin/project/edit?…”
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A Novel Rose Hip Preparation with Enhanced Anti-Inflammatory and Chondroprotective Effects by Joseph Schwager, Nathalie Richard, Rotraut Schoop, Swen Wolfram

“…RH preparations from fruits without seeds are thus expected to have an improved OA-preventive or OA-therapeutic profile, as subsequently shown in a related clinical trial.…”
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Effect of Dynamic Neuromuscular Stabilization Exercises on Activity of External Oblique Muscle in Low Back Pain by Hediyeh Hosseini, Abbas Rahimi, Khodabakhsh Javanshir, Mohammad Taghipour, Aliyeh Daryabor, Sedigheh Sadat Naimi

“…Materials and Methods: In a randomized clinical trial, 44 people with chronic NSLBP were randomly assigned to the experimental and the control groups, with 22 participants in each group. …”
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The Pharmacodynamic Impact of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, on Circulating Levels of Inflammatory Biomarkers in Patients with Psoriatic Arthritis: Substudy Res... by Peter H. Schafer, Peng Chen, Lorraine Fang, Andrew Wang, Rajesh Chopra

“…Apremilast, an oral phosphodiesterase 4 inhibitor, demonstrated effectiveness (versus placebo) for treatment of active psoriatic arthritis in the psoriatic arthritis long-term assessment of clinical efficacy (PALACE) phase III clinical trial program. Pharmacodynamic effects of apremilast on plasma biomarkers associated with inflammation were evaluated in a PALACE 1 substudy. …”
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A systematic review of Aspilia africana (Pers.) C.D. adams traditional medicinal uses, phytoconstituents, bioactivities, and toxicities by Roggers Gang, Denis Okello, Yeongjun Ban, Youngmin Kang

“…Additionally, toxicity and clinical trial data for A. africana are limited with most toxicological assessments being acute in nature. …”
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Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases by Shih-Wen Huang, Yein-Gei Lai, Hao-Ting Liao, Chin-Ling Chang, Ruo-Yu Ma, Yung-Hsiang Chen, Yae-Huei Liou, Zhen-Qi Wu, Yu-Chen Wu, Ko-Jiunn Liu, Yen-Tsung Huang, Jen-Lung Yang, Ming-Shen Dai, Nan-Shih Liao

“…We conducted an investigator-initiated clinical trial of autologous NK cell therapy in six patients with advanced cancer and observed that the NK cell therapy was safe and showed signs of effectiveness. …”
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Excessive Daytime Sleepiness among Hypertensive US-Born Blacks and Foreign-Born Blacks: Analysis of the CAATCH Data by N. Williams, O. Abo Al Haija, A. Workneh, D. Sarpong, E. Keku, G. Ogedegbe, S. I. McFarlane, G. Jean-Louis

“…CAATCH is a group randomized clinical trial that was conducted among 30 community healthcare centers in New York, yielding baseline data for 1,058 hypertensive black patients. …”
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Prospects of Using Microbiota Correction Methods in the Treatment of Inflammatory Bowel Disease by A. I. Akinshina, D. V. Smirnova, A. V. Zagainova, V. V. Makarov, S. M. Yudin

“…The present article examines key methods of microbiota correction (antibiotic therapy; pro-, pre- and metabiotic therapy; faecal microbiota transplantation) used in treating inflammatory bowel disease, as well as compares the clinical trial results of these methods.Key findings. …”
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