The Effect of Synbiotic Supplementation on Self-Reported Aggression in Healthy Adult Men: A Randomized, Double-Blind, Placebo-Controlled Trial by Rahele Sadat Montazeri, Farzad Shidfar, Fatemeh Sadat Hosseini-Baharanchi, Golraste Kholasezadeh

“…Methods: This double-blind randomized controlled clinical trial was conducted on 100 healthy adult men working at Iran University of Medical Sciences. …”
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Mesenchymal Stem Cell-Educated Macrophages Ameliorate LPS-Induced Systemic Response by Yaoqin Hu, Chaojin Qin, Guoping Zheng, Dengming Lai, Huikang Tao, Yan Zhang, Guanguan Qiu, Menghua Ge, Lanfang Huang, Lina Chen, Baoli Cheng, Qiang Shu, Jianguo Xu

“…When macrophages were cultured with serum from ARDS patients who were treated with ASCs or placebo in our previous clinical trial, there was no difference in M2 macrophage levels before and after ASCs treatment indicating a suboptimal response to the treatment protocol. …”
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Timing of Acupuncture during LTP-Like Plasticity Induced by Paired-Associative Stimulation by Xiao-kuo He, Qian-qian Sun, Hui-hua Liu, Xin-yi Guo, Cheng Chen, Li-dian Chen

“…This trial was registered in the Chinese Clinical Trial Registry (registration no. ChiCTR-IPR-1900020515).…”
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The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy by Ayyoub Barzegarnezhad, Abolfazl Firouzian, Seyed Abdollah Emadi, Nadali Mousanejad, Roksana Bakhshali

“…In this double-blind randomized clinical trial, 120 patients with ureteral stones were enrolled and randomized into two groups. …”
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Comparison of Dexmedetomidine with Acetaminophen and Its Combination (Apodex) on Pain Control, Emergence Agitation and Delirium in Pediatric Patients Undergoing Adenotonsillectomy... by farzad sarshivi, negin ghadami, karim naseri, soraya sarshivi

“…Materials and Methods: In this randomized double-blind clinical trial, 132 patients, between 2 and 12 years, candidates for adenotonsillectomy were examined in four groups (n=33). …”
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Inhibition of P38 MAPK Downregulates the Expression of IL-1β to Protect Lung from Acute Injury in Intestinal Ischemia Reperfusion Rats by De-Yi Zheng, Min Zhou, Jiao Jin, Mu He, Yi Wang, Jiao Du, Xiang-Yang Xiao, Ping-Yang Li, Ai-Zhu Ye, Jia Liu, Ting-Hua Wang

“…Our findings indicate that the inhibition of P38 α and β may downregulate the expression of IL-1β to protect lung from acute injury in II/R, which could be used as a potential target for reducing ALI induced by II/R in the future clinical trial.…”
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Oral Fludrocortisone Test for Salt-Sensitive Screening in Hypertensive Patients: A Randomized Crossover Trial by Andrea Pio-Abreu, Isac de Castro, Giovanio Vieira da Silva, Katia Coelho Ortega, Decio Mion

“…However, the low specificity prevents this test from being an ideal substitute to the labor-intensive diet cycles exam in the definition of salt sensitivity. This clinical trial is registered with NCT01453959.…”
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Achieving the Recommended Endotracheal Tube Cuff Pressure: A Randomized Control Study Comparing Loss of Resistance Syringe to Pilot Balloon Palpation by Fred Bulamba, Andrew Kintu, Nodreen Ayupo, Charles Kojjo, Lameck Ssemogerere, Agnes Wabule, Arthur Kwizera

“…This was a randomized clinical trial. We enrolled adult patients scheduled to undergo general anesthesia for elective surgery at Mulago Hospital, Uganda. …”
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Home-based transcranial direct current stimulation paired with cognitive training to reduce fatigue in multiple sclerosis by Leigh Charvet, Judith D. Goldberg, Xiaochun Li, Pamela Best, Matthew Lustberg, Michael Shaw, Lana Zhovtis, Josef Gutman, Abhishek Datta, Marom Bikson, Giuseppina Pilloni, Lauren Krupp

“…We conducted a double-blind, sham-controlled, randomized clinical trial to compare active vs. low-dose (sham) tDCS paired with computer-based cognitive training, delivered as a home-based intervention, to reduce MS-related fatigue. …”
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Effects of Lactobacillus gasseri OLL2716 on Helicobacter pylori-Associated Dyspepsia: A Multicenter Randomized Double-Blind Controlled Trial by Atsushi Takagi, Hidetaka Yanagi, Hideki Ozawa, Naomi Uemura, Shigemi Nakajima, Kazuhiko Inoue, Takashi Kawai, Toshihiro Ohtsu, Yasuhiro Koga

“…This study was registered at the University Hospital Medical Network Clinical Trial Registry (UMIN000016746).…”
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Effects of Low-Dose Testosterone Undecanoate Treatment on Bone Mineral Density and Bone Turnover Markers in Elderly Male Osteoporosis with Low Serum Testosterone by Yan-Jiao Wang, Jun-Kun Zhan, Wu Huang, Yi Wang, Yuan Liu, Sha Wang, Pan Tan, Zhi-Yong Tang, You-Shuo Liu

“…This prospective 2-year, single-center, randomized, placebo-controlled, open-label clinical trial was performed to evaluate the efficacy of low-dose testosterone undecanoate (TU) treatment on bone mineral density (BMD) and biochemical markers of bone turnover in elderly male osteoporosis with low serum testosterone. …”
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Pembrolizumab as first-line treatment for recurrent and metastatic head and neck cancer – real-world single-centre data by Bogdana Patachi, Kristian H. Jensen, Anita Gothelf, Mogens Bernsdorf, Jeppe Friborg, Claus A. Kristensen

“…Background and purpose: The randomised clinical trial KEYNOTE-048 has demonstrated a significant increase in survival for patients with head and neck cancer treated with pembrolizumab with or without chemotherapy. …”
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Cognitive Stimulation for Apathy in Probable Early-Stage Alzheimer's by Linda L. Buettner, Suzanne Fitzsimmons, Serdar Atav, Kaycee Sink

“…We studied changes in apathy among 77 community-dwelling older persons with mild memory loss in a randomized clinical trial comparing two nonpharmacological interventions over four weeks. …”
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A Randomized Controlled Trial of Chinese Medicine on Nonmotor Symptoms in Parkinson’s Disease by Ka-Kit Chua, Adrian Wong, Kam-Wa Chan, Yin-Kei Lau, Zhao-Xiang Bian, Jia-Hong Lu, Liang-Feng Liu, Lei-Lei Chen, Ka-Ho Chan, Kim-Pong Tse, Anne Chan, Ju-Xian Song, Justin Wu, Li-Xing Zhu, Vincent Mok, Min Li

“…Here we report a double-blind, randomized, placebo-controlled, add-on clinical trial aiming at evaluating the efficacy and safety of the JLT in treating NMS in PD patients. …”
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Analgesia Evaluation of 2 NSAID Drugs as Adjuvant in Management of Chronic Temporomandibular Disorders by Fernando Kurita Varoli, Murillo Sucena Pita, Sandra Sato, João Paulo Mardegan Issa, Cássio do Nascimento, Vinícius Pedrazzi

“…The aim of this triple-blind full-randomized clinical trial was to quantify analgesia in masticatory muscles and temporomandibular joints after occlusal splint therapy associated with the adjuvant administration of nonsteroidal anti-inflammatory drugs (NSAID) isolated or associated with other therapeutic agents. …”
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Radiotherapy for Oligometastases and Oligo-Recurrence of Bone in Prostate Cancer by Ken-ichi Tabata, Yuzuru Niibe, Takefumi Satoh, Hideyasu Tsumura, Masaomi Ikeda, Satoru Minamida, Tetsuo Fujita, Daisuke Ishii, Masatsugu Iwamura, Kazushige Hayakawa, Shiro Baba

“…Pathological fracture and SCC were not seen at the treated sites. A larger clinical trial is warranted to study the actual benefit following radiotherapy for oligometastases of bone in PCa.…”
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Association between the C-reactive protein–albumin–lymphocyte index and metabolic syndrome: evidence from the 2003–2010 national health and nutrition examination survey by Lanlan Wu, Dunzheng Han, Yuting Xue, Shangfei He, Zhuang Ma, Shuwen Su, Peixin Li, Shenrong Liu, Haobin Zhou

“…The CALLY index might be valuable for identifying individuals who are at a high risk of MetS. Clinical trial number Not applicable.…”
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Hemorheological Alterations in Patients with Heart Failure with Reduced Ejection Fraction Treated by Resveratrol by Roland Gal, Dora Praksch, Peter Kenyeres, Miklos Rabai, Kalman Toth, Robert Halmosi, Tamas Habon

“…In our double-blind, placebo-controlled human clinical trial, we enrolled 60 outpatients with heart failure. …”
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Profile of Chlamydia vaccine research: A bibliometric analysis by Xuemei Wang, Qian Wang, Yidan Gao, Lijuan Jiang, Lingli Tang

“…However, to date, no vaccine has successfully completed the rigorous clinical trial process and gained regulatory approval for use in clinical practice. …”
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Balanced Suspension versus Pillow on Preoperative Pain for Proximal Femur Fractures: A Randomized Controlled Trial by Varah Yuenyongviwat, Chonthawat Jiarasrisatien, Khanin Iamthanaporn, Theerawit Hongnaparak, Boonsin Tangtrakulwanich

“…Hence, other methods for reducing pain, while waiting for definite operations, should be focused on. The clinical trial is registered with TCTR20150514002.…”
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