Evaluation of anterior fixed appliances on maxillary arch growth in preschool children by Mohamed Ghaly, Nahed Abo Hamila

“…The study was conducted as a clinical trial and it was carried out at Pediatric Dentistry Department, Faculty of Dentistry, Tanta University. …”
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Vascular Endothelial Growth Factor (VEGF) Family and the Immune System: Activators or Inhibitors? by Cristina Maria Failla, Maria Luigia Carbone, Carmela Ramondino, Emanuele Bruni, Angela Orecchia

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Fecal DNA Screening in Colorectal Cancer by Suzanne Richter

“…Current challenges include cost reduction and demonstration of mortality benefit in a rigorous clinical trial. Despite current challenges, fecal DNA testing is worth pursuing. …”
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CYP2A6 Polymorphisms May Strengthen Individualized Treatment for Nicotine Dependence by Yawo Mawuli Akrodou

“…., CYP2A6*1H, CYP2A6*4A, CYP2A6*9, and CYP2A6*12A) are associated with underrated nicotine metabolizing activity (50%–75%), linking them to low scores for nicotine dependence (0–4) on the FTND scale. In a clinical trial involving the use of bupropion, people who were carriers of slow nicotine metabolizers were found to have a tendency to maintain abstinence 1.7 times longer than people with normal nicotine metabolizers. …”
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Understanding tinnitus symptom dynamics and clinical improvement through intensive longitudinal data by Milena Engelke, Jorge Piano Simões, Laura Basso, Nina Wunder, Berthold Langguth, Thomas Probst, Rüdiger Pryss, Winfried Schlee

“…App data from a multi-center randomized clinical trial were analysed using time-series feature extraction and nested cross-validated ordinal regression with elastic net regulation to predict clinical improvement based on the Clinical Global Impression—Improvement scale (CGI-I). …”
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Proliferative Vitreoretinopathy after Eye Injuries: An Overexpression of Growth Factors and Cytokines Leading to a Retinal Keloid by Francesco Morescalchi, Sarah Duse, Elena Gambicorti, Mario R. Romano, Ciro Costagliola, Francesco Semeraro

“…This paper reviews the current literature and clinical trial data on the pathogenesis of PVR and its correlation with ocular trauma and describes the biochemical/molecular events that will be fundamental for the development of novel treatment strategies. …”
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Noni Juice Improves Serum Lipid Profiles and Other Risk Markers in Cigarette Smokers by Mian-Ying Wang, Lin Peng, Vicki Weidenbacher-Hoper, Shixin Deng, Gary Anderson, Brett J. West

“…One hundred thirty-two adult heavy smokers completed a randomized, double blind, placebo-controlled clinical trial designed to investigate the effect of noni juice on serum cholesterol, triglyceride, low density lipoprotein cholesterol (LDL), high density lipoprotein cholesterol (HDL), high-sensitivity C-reactive protein (hs-CRP), and homocysteine. …”
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TNG908 is a brain-penetrant, MTA-cooperative PRMT5 inhibitor developed for the treatment of MTAP-deleted cancers by Kimberly J. Briggs, Kevin M. Cottrell, Matthew R. Tonini, Alice Tsai, Minjie Zhang, Douglas A. Whittington, Wenhai Zhang, Steven A. Lombardo, Satoshi Yoda, Erik W. Wilker, Samuel R. Meier, Yi Yu, Teng Teng, Alan Huang, John P. Maxwell

“…TNG908 is being tested clinically in patients with MTAP-deleted tumors, including glioblastoma, in a Phase I/II clinical trial (NCT05275478).…”
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Aerobic Exercise Improves Signs of Restless Leg Syndrome in End Stage Renal Disease Patients Suffering Chronic Hemodialysis by Mojgan Mortazavi, Babak Vahdatpour, Aida Ghasempour, Diana Taheri, Shahrzad Shahidi, Firouzeh Moeinzadeh, Bahareh Dolatkhah, Shahaboddin Dolatkhah

“…In this randomized clinical trial we aimed to find a nonpharmacological way to improve signs of restless leg syndrome and patients’ quality of life. …”
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Testosterone exacerbates neutrophilia and cardiac injury in myocardial infarction via actions in bone marrow by Elin Svedlund Eriksson, Marta Lantero Rodriguez, Bente Halvorsen, Inger Johansson, Anna K. F. Mårtensson, Anna S. Wilhelmson, Camilla Huse, Thor Ueland, Pål Aukrust, Kaspar Broch, Lars Gullestad, Brage Høyem Amundsen, Geir Øystein Andersen, Mikael C. I. Karlsson, Malin Hagberg Thulin, Alessandro Camponeschi, Dana Trompet, Ola Hammarsten, Björn Redfors, Jan Borén, Elmir Omerovic, Malin C. Levin, Andrei S. Chagin, Tuva B. Dahl, Åsa Tivesten

“…Post-hoc analysis of clinical trial data showed that neutrophilia was greater in men than women after reperfusion of first-time ST-elevation MI, and tocilizumab, an interleukin-6 receptor inhibitor, reduced blood neutrophil counts and infarct size to a greater extent in men than women. …”
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Malaria Vaccine Development: Are Bacterial Flagellin Fusion Proteins the Bridge between Mouse and Humans? by Daniel Y. Bargieri, Irene S. Soares, Fabio T. M. Costa, Catarina J. Braga, Luis C. S. Ferreira, Mauricio M. Rodrigues

“…The recent report of the first Phase I clinical trial of a vaccine containing a Salmonella flagellin as carrier/adjuvant may fuel the use of these proteins in vaccine formulations. …”
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Focusing on Sodium Glucose Cotransporter-2 and the Sympathetic Nervous System: Potential Impact in Diabetic Retinopathy by Lakshini Y. Herat, Vance B. Matthews, P. Elizabeth Rakoczy, Revathy Carnagarin, Markus Schlaich

“…Excitingly, the EMPA-REG clinical trial, which focuses on the clinically used SGLT2 inhibitor empagliflozin, has been extremely fruitful and has highlighted beneficial cardiovascular and renal outcomes. …”
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Does the “state of disaster” response have a downside? Hospital incident command group leaders’ experiences of a terrorist-induced major incident: a qualitative study by Jason P. Murphy, Anna Hörberg, Monica Rådestad RN, Lisa Kurland, Maria Jirwe

“…In addition, the results suggest that an exaggerated response may have led to unanticipated adverse events. Clinical trial number Not applicable.…”
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Comparison of the effects of nicardipine and remifentanil on surgical visual field and hemodynamic parameters in tympanomastoidectomy cases by Celal Saritoy, Erol Karaaslan, Ahmet Selim Ozkan, Mehmet Tan, Ilham Gulcek

“…The study was planned as a prospective, double-blind, and randomized clinical trial. A total of 64 patients aged between 18 and 65 were included in the study and the patients were randomized into 2 groups: Group N (Nicardipine=32) and Group R (Remifentanil=32). …”
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Daily versus three-times-weekly azithromycin in Chinese patients with non-cystic fibrosis bronchiectasis: protocol for a prospective, open-label and randomised controlled trial by Jing Li, Fei Chen, Wei Xiao, Feng Li, Lan Chen, Ting He, Yanxiong Mao, Aiping Zou, Bo Fan, Weihao Ni, Huimin You, Wenjiang Fu

“…This protocol describes a head-to-head clinical trial designed to compare the efficacy of two dosing regimens of azithromycin in Chinese NCFB population.Methods and analysis This prospective, open-label and randomised controlled trial will be conducted in the First People’s Hospital of Jiashan, China. …”
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Skin-Derived Stem Cells for Wound Treatment Using Cultured Epidermal Autografts: Clinical Applications and Challenges by Inga Brockmann, Juliet Ehrenpfordt, Tabea Sturmheit, Matthias Brandenburger, Charli Kruse, Marietta Zille, Dorothee Rose, Johannes Boltze

“…We further provide an overview of clinical trial activities in the field and discuss relevant translational and clinical challenges associated with the use of these products.…”
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Randomized controlled trial on the efficacy of forest walking compared to urban walking in enhancing mucosal immunity by Hiroko Ochiai, Shigeru Inoue, Gaku Masuda, Shiho Amagasa, Tomohiko Sugishita, Toshiya Ochiai, Naoko Yanagisawa, Yoshio Nakata, Michiko Imai

“…In conclusion, mindful forest walking has the potential to enhance immunity and promote health. Clinical trial registration: University Hospital Medical Information Network. …”
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Dosimetric Comparison of Noncoplanar VMAT Without Rotating the Patient Couch Versus Conventional Coplanar/Noncoplanar VMAT for Head and Neck Cancer: First Report of Dynamic Swing A... by Kouta Hirotaki, MS, Kento Tomizawa, MD, PhD, Satoe Kitou, BS, Shunta Jinno, MS, Shunsuke Moriya, PhD, Takeshi Fujisawa, MD, Sadamoto Zenda, MD, PhD, Takeji Sakae, PhD, Masashi Ito, BS

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When specific exercise is more effective than medication - Sensorimotor training is currently the most promising option to treat and prevent chemotherapy-induced peripheral neuropa... by Fiona Streckmann, Maryam Balke, Céline Hammadou, Bianca Schmidli, Oliver Faude, Sarah Koch

“…Methods we performed a prospective multicenter randomized clinical trial (STOP) and followed up patients over 5 years (May 2014 – Nov. 2020) at 4 centers and around Cologne, Germany. …”
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Pengaruh Terapi Oksigen Menggunakan Non-Rebreathing Mask Terhadap Tekanan Parsial CO2 Darah pada Pasien Cedera Kepala Sedang by Hendrizal ., Syaiful Saanin, Hafni Bachtiar

“…Metode: Penelitian ini merupakan penelitian Clinical Trial dengan rancangan penelitian one shoot pretest and postest pada pasien cedera kepala sedang dengan GCS 9-13 yang dilakukan terapi konservatif di RS Dr. …”
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