Key tips to shift student perspectives through transformative learning in medical education by Efraim J. Hart, Merel H. de Heer-Koster, Maria van der Harst, Joyce L. Browne, Fedde Scheele

“…The potential impact of these tips on medical education is substantial, as they provide a pathway toward a more responsive, ethical, and sustainable future of healthcare. Clinical trial number: Not applicable.…”
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Living, Caring, Learning - Thinking outside the box to solve care challenges in a rare blood disorder by Hibner Sandra

“…Symptoms of the girl’s disorder were evident from birth and through an emergency use request Sandra and the care team enabled her family to access a treatment that at the time was in clinical trial. Poor venous access meant there was a need to adapt how treatment was administered and she worked with the girl’s parents to ensure that she was treated effectively. …”
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Developing an Appropriate Digital Hearing Aid for Low-Resource Countries: A Case Study by P. Israsena, S. Isaradisaikul, A. Noymai, S. Boonyanukul, A. Hemakom, C. Chinnarat, N. Navacharoen, S. Lekagul

“…Clinically it had undergone a full clinical trial that employed the outcome measurement protocol adopted from the APHAB, the first time implemented in Thai language. …”
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Synergistic Effect of Adjustments of Elastic Stockings to Maintain Reduction in Leg Volume after Mechanical Lymph Drainage by José Maria Pereira de Godoy, Renata Lopes Pinto, Ana Carolina Pereira de Godoy, Maria de Fátima Guerreiro Godoy

“…Eleven patients with Grade II leg lymphedema, regardless of etiology, were evaluated in a randomized clinical trial. The ages ranged from 47 to 83 years old with a mean of 62.4 years. …”
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Anti‐tumor drug supervision in China from 2010 to 2024: the evolution and prospect of drug review standards by Ling Tang, Yuanyuan Song, Hong Zhang, Ruimin Hao, Xin Tong, Xing Ai, Jun Ma, Zhimin Yang

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5-Aminosalicylic Acid Enemas in the Maintenance of Remission in Distal Ulcerative Colitis and Proctitis by Lloyd R Sutherland, Francois Martin

“…A randomized clinical trial of the efficacy and safety of two different dosages of 5-aminosalicylic acid (5-ASA) enemas was carried out in 29 patients who had documented ulcerative colitis involving up to 50cm of distal colon. …”
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Effect of periodontal therapy on endothelial function and serum biomarkers in patients with periodontitis and established cardiovascular disease: a pilot study by Ana Molina, Nagore Ambrosio, María Molina, Eduardo Montero, Leire Virto, David Herrera, Elena Figuero, Mariano Sanz

“…AimTo investigate the effect of periodontal therapy on endothelial function of subjects with periodontitis in stages III or IV and established cardiovascular disease.Materials and methodsA triple-blinded, parallel groups, randomized clinical trial of 6 months duration, on patients with history of coronary heart disease and periodontitis in stages III or IV was performed. …”
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Multi-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury by Ren Zhou, Jibao Chen, Yunhan Tang, Chuijin Wei, Ping Yu, Xinmei Ding, Li’ao Zhu, Jiajia Yao, Zengqiang Ouyang, Jing Qiao, Shumin Xiong, Liaoliao Dong, Tong Yin, Haiqing Li, Ye Feng, Lin Cheng

“…Methods We conducted a randomized controlled clinical trial investigating the effects of resistance exercise therapy for incomplete SCI. …”
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Non-Viral Delivery Systems to Transport Nucleic Acids for Inherited Retinal Disorders by Md Jobair Jony, Ameya Joshi, Alekha Dash, Surabhi Shukla

“…Additionally, this review covers recent clinical trial developments in gene therapy for retinal disorders.…”
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The Amelioration of Detrimental Biochemical Anomalies by Supplementing B, C, and E Vitamins in Subjects with Type 2 Diabetes Mellitus May Reduce the Rate of Development of Diabetic... by Subhasish Pramanik, Kaustav Banerjee, Lakshmi Kanta Mondal

“…In this prospective clinical trial, 185 patients with T2DM who received B vitamins, vitamin C, and vitamin E along with antidiabetic medication for five years demonstrated a slower rate of the development of DR and reduced abnormal biochemical mediators like reactive oxygen species (ROS), malondialdehyde (MDA), AGE, and vascular endothelial growth factor (VEGF) compared to 175 T2DM individuals who were treated with only antihyperglycemic drugs.…”
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Pulsed Electromagnetic Field Therapy as a Complementary Alternative for Chronic Pelvic Pain Management in an Interstitial Cystitis/Bladder Pain Syndrome Patient by Tyler L. Overholt, Christina Ross, Robert J. Evans, Stephen J. Walker

“…This case provides support for a formal clinical trial to evaluate the efficacy of pulsed electromagnetic field therapy for the management of chronic pelvic pain in interstitial cystitis/bladder pain syndrome.…”
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Management of Class I and Class II Amalgam Restorations with Localized Defects: Five-Year Results by Javier Martin, Eduardo Fernandez, Juan Estay, Valeria V. Gordan, Ivar Andreas Mjör, Gustavo Moncada

“…This five-year prospective clinical trial evaluated amalgam restorations with localized defects that were treated by means of repair or refurbishing. …”
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An Alternative Sensitivity Approach for Longitudinal Analysis with Dropout by Amal Almohisen, Robin Henderson, Arwa M. Alshingiti

“…We apply the local misspecification and least false methods to estimate the bias and sensitivity of parameter estimates for a clinical trial example.…”
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Biomarker-Based Targeting of the Androgen-Androgen Receptor Axis in Advanced Prostate Cancer by Manish Kohli, Rui Qin, Rafael Jimenez, Scott M. Dehm

“…Specific examples of rational clinical trial designs incorporating potential predictive biomarkers from these pathways will illustrate several aspects of pharmacogenetic and pharmacogenomic predictive biomarker development in advanced prostate cancer therapeutics.…”
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Comparative Numerical Analysis between Two Types of Orthodontic Wire for the Lingual Technique, Using the Finite Element Method by Rosa Alicia Hernández-Vázquez, Rodrigo Arturo Marquet-Rivera, Octavio Alejandro Mastache-Miranda, Angel Javier Vázquez-López, Salvador Cruz-López, Juan Alejandro Vázquez-Feijoo

“…The present study establishes the bases so that it is possible to find the indications for each type of wire. A clinical trial of a lingual orthodontic patient was used. …”
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Sex differences in the association between repetitive negative thinking and neurofilament light by Yolanda Lau, Amit Bansal, Cassandre Palix, Harriet Demnitz-King, Miranka Wirth, Olga Klimecki, Gael Chetelat, Géraldine Poisnel, Natalie L. Marchant, The Medit-Ageing Research Group

“…Baseline data from 134 cognitively healthy older adults in the Age-Well clinical trial were utilised. Worry and brooding were assessed using questionnaires. …”
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Prediction of individual patient outcomes to psychotherapy vs medication for major depression by Devon LoParo, Boadie W. Dunlop, Charles B. Nemeroff, Helen S. Mayberg, W. Edward Craighead

“…We used machine learning to develop predictor variables that combined demographic and clinical items from a randomized clinical trial. The variables predicted a meaningful proportion of variance in end-of-treatment depression severity for cognitive behavioral therapy (39.7%), escitalopram (32.1%), and duloxetine (67.7%), leading to a high accuracy in predicting remission (71%). …”
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Impact of rapid antibiotic susceptibility testing for Gram-negative bacteremia varies by pathogen type and resistance: a secondary analysis of the RAPIDS GN trial by Ritu Banerjee, Abhigya Giri, Lauren Komarow, Maria Souli, Sarah B. Doernberg, Robin Patel

“…This analysis of patients with sepsis previously enrolled in a randomized controlled clinical trial demonstrates that rapid susceptibility testing of bacteria from blood cultures had the greatest impact for patients with antibiotic-resistant infections. …”
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Early screening of lung function by electrical impedance tomography in people with normal spirometry reveals unrecognized pathological features by Shuoyao Qu, Enzhi Feng, Daihan Dong, Lin Yang, Meng Dai, Inéz Frerichs, Shaojie Liu, Yi Gao, Jinping Zheng, Liqiang Song, Zhanqi Zhao

“…The regional time constant based on electrical impedance tomography can be a promising tool for early screening of lung function impairment. Clinical trial registration: ChiCTR2300076673, www.chictr.org.cn .…”
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A Novel Curcumin-Based Drug Powder Inhalation Medicine for Chronic Obstructive Pulmonary Disease by Qin Shen, Yongjie Jiang, Jing Chen, Xueling Wang, Jiao Zheng

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