Development and validation of a prognostic prediction model for elderly gastric cancer patients based on oxidative stress biochemical markers by Xing-Qi Zhang, Ze-Ning Huang, Ju Wu, Chang-Yue Zheng, Xiao-Dong Liu, Ying-Qi Huang, Qi-Yue Chen, Ping Li, Jian-Wei Xie, Chao-Hui Zheng, Jian-Xian Lin, Yan-Bing Zhou, Chang-Ming Huang

“…Trial registration Retrospectively registered at ClinicalTrials.gov (trial registration number: NCT06208046, date of registration: 2024–05-01).…”
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Service delivery and the role of clinical pharmacists in UK primary care for older people, including people with dementia: a scoping review by Alice Burnand, Abi Woodward, Vladimir Kolodin, Jill Manthorpe, Yogini Jani, Mine Orlu, Cini Bhanu, Kritika Samsi, Victoria Vickerstaff, Jane Wilcock, Jane Ward, Greta Rait, Nathan Davies

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Clinical efficacy of Tuina therapy combined with traditional Chinese exercises in the treatment of symptomatic lumbar disc herniation: a multicentre randomised controlled trial pro... by Zhihong Fan, Shenghong Jia, Xin Zhou, Chao Li, Jiahao Shao, Xiaofeng Liu, Yitao Liao, Yenan Xu, Dandan He, Shixiang Wu, Xian Zhang

“…However, the majority of current clinical trials on the treatment of LDH with Tuina or TCEs are single-centre clinical studies, and the quality of these studies is generally low. …”
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Mechanistic investigation and the optimal dose based on baicalin in the treatment of ulcerative colitis–A preclinical systematic review and meta-analysis by Jinchen Chong, Zepeng Chen, Jiaze Ma, Linhai He, Yijia Zhu, Zhihua Lu, Zhengxi Qiu, Chen Chen, Yugen Chen, Feng Jiang

“…While higher doses and longer treatments appear beneficial, further research, particularly human clinical trials, is necessary to verify its effectiveness and safety in people.…”
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Effects of Combined Intrathecal Mesenchymal Stem Cells and Schwann Cells Transplantation on Neuropathic Pain in Complete Spinal Cord Injury: A Phase II Randomized Active-Controlled... by Mohammadhosein Akhlaghpasand, Roozbeh Tavanaei, Maede Hosseinpoor, Reza Heidari, Ida Mohammadi, Mohsen Chamanara, Melika Hosseinpour, Alireza Zali, Reza Mosaed, Saeed Oraee-Yazdani

“…Future investigations should evaluate the effects of combination of this strategy with other existing therapies for SCI-induced neuropathic pain. This clinical trial was also registered prospectively at the Iranian Registry of Clinical Trials (IRCT20200502047277N8).…”
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Assessing the effect of On-site supportive communication training (On-site SCT) on doctor burnout: a randomized controlled trial by K.K. Antonsen, J.D. Lyhne, A.T. Johnsen, S. Eßer-Naumann, L.Ø. Poulsen, L. Lund, S. Timm, L.H. Jensen

“…Trial registration December 2022– The Region of Southern Denmark (22/57137). April 2023– ClinicalTrials.gov (NCT05842083). April 2023– The Research Ethics Committee at the University of Southern Denmark (23/19397).…”
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Very first real-world data on zongertinib use in non-small cell lung cancer patients with HER2 mutations: A brief report by Oliver Illini, Anna Sophie Lang-Stöberl, Hannah Fabikan, Christoph Weinlinger, Arschang Valipour, Maximilian J. Hochmair

“…New agents, including zongertinib, a HER2-selective tyrosine kinase inhibitor (TKI), are being investigated in clinical trials. However, published clinical data on the efficacy and safety of zongertinib are limited to data from a single phase I trial including only 36 patients with NSCLC. …”
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Comparison of efficacy and safety of thrombus prevention strategies after abdominal and pelvic cancer surgery: Bayesian network based meta-analysis by Shiran Qin, Shiran Qin, Sitong Guo, Yucheng Yao, Yucheng Yao, Ying He, Dandan Xu, Dandan Xu, Henghai Su, Xiaoyu Chen, Haoru Meng

“…Network meta-analysis(NMA) and direct meta-analysis (DMA) methods were employed to evaluate the efficacy and safety of various prophylactic strategies.ResultsTwenty clinical trials involving a total of 4923 patients were included. …”
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Osteoarthritis and Degree of Fatigue are Associated with Pain Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study of 394 Patients by Wang Z, Lan T, Zhang Y, Guo Z, Yu H, Sun G, Wang Z, Yan Z, Tao Q, Xu Y

“…The interaction analyses revealed a significant association between OA and degree of fatigue, which were related to the pain level of patients with FMS synergistically.Conclusion: Patients with FMS experience coexisting OA and a high degree of fatigue, which interact synergistically, being correlated with increased pain levels.Trial Registration: The study was approved by the Clinical Research Ethics Committee of the China-Japan Friendship Hospital (2022-KY-079) and registered on ClinicalTrials.gov (NCT05508516) on August 17th, 2022.Keywords: fibromyalgia syndrome, osteoarthritis, fatigue, pain, correlation analysis…”
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Deep Lateral Wall Partial Rim-Sparing Orbital Decompression with Ultrasonic Bone Removal for Treatment of Thyroid-Related Orbitopathy by Álvaro Bengoa-González, Alicia Galindo-Ferreiro, Enrique Mencía-Gutiérrez, Hortensia Sánchez-Tocino, Agustín Martín-Clavijo, María-Dolores Lago-Llinás

“…This trial is registered with ClinicalTrials.gov identifier: NCT04025034.…”
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Fecal Microbiota Transplantation: A Systematic Review of Therapeutic Potential, Preparation Techniques, and Delivery Methods Across Medical Conditions by Syamand Ahmed Qadir, Qausar Hamed ALKaisy, Abdulbasit F. Hasan, Farhang Hameed Awlqadr, Ammar B. Altemimi, Aryan Mahmood Faraj, Angelo Maria Giuffrè, Mohammed N. Saeed, Sherzad Rasul Abdalla

“…A comprehensive search of PubMed, Web of Science, Scopus, Embase, and ClinicalTrials.gov from January 2000 to December 2023 identified 97 relevant studies on FMT's efficacy, safety, and microbiome changes after eliminating duplicates. …”
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Discovery of a non‐nucleotide stimulator of interferon genes (STING) agonist with systemic antitumor effect by Xiyuan Wang, Zhengsheng Zhan, Zhen Wang, Yan Zhang, Kaiyan Zhao, Han Li, Xiaoqian Zhou, Yuting Guo, Fengying Fan, Jian Ding, Meiyu Geng, Xuekui Yu, Wenhu Duan, Zuoquan Xie

“…Although progress in clinical trials for STING agonists in antitumor applications has been slow, there is still an urgent need for developing new potent STING agonists with versatile potential applications. …”
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Stemness Maintenance Properties in Human Oral Stem Cells after Long-Term Passage by Francesca Diomede, Thangavelu Soundara Rajan, Valentina Gatta, Marco D’Aurora, Ilaria Merciaro, Marco Marchisio, Aurelio Muttini, Sergio Caputi, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani

“…Our results suggest that the presence of embryonic and proliferation markers even in late passage may potentially endorse the application of dental-derived MSCs in stem cell therapy-based clinical trials.…”
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Acute Concurrent Exercise Improves Inhibitory Control Without Mediating the Role of Lactate: An Event-Related Potential Study by Ruei-Hong Li, Tai-Rui Chen, Nicholas D. Gilson, Marius Brazaitis, Yi-Ting Cheng, Hui-Fang Wu, Ji-Hang Lee, Yu-Kai Chang

“…Trial registration: ClinicalTrials.gov, NCT06370286. Registered 12 April 2024—Retrospectively registered, https://clinicaltrials.gov/study/NCT06370286 .…”
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A prospective randomized controlled trial comparing biphasic cartilage repair implant with microfracture in small chondral lesions of knee: findings at five-year-follow-up by Yao-Yi Kuo, Si-Qi Chiu, Wen-Pei Chang, Chih-Yu Chen, Chih-Hwa Chen, Chen-Kun Liaw, Cheng-Aun Tan, Pei-Wei Weng

“…Methods This randomized controlled clinical trial enrolled patients with symptomatic knee chondral lesions smaller than 3 cm2. …”
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Genetic profiling of extended-spectrum β-Lactamase and carbapenemase-producing Escherichia coli O157:H7 from clinical samples among diarrheal patients in Shashemene, Ethiopia by Shimelis Teshome Ayalneh, Biruk Yeshitela Beshah, Yeonji Jeon, Ashenafi Alemu Wami, Seifegebriel Teshome, Solomon Gebreselassie, Se Eun Park, Mekonnen Teferi, Woldaregay Erku Abegaz

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Feasibility and preliminary efficacy of a physical activity intervention in adults with lymphoma undergoing treatment by Juliana V. Costa, Alexander R. Lucas, Shannon L. Mihalko, Peter H. Brubaker, Alexandra Marshall, Brianna Leitzelar, Brianna R. Wolle, Samuel Norton, R. Lee Franco, Jeremy Via, Victor Yazbeck, Rakhee Vaidya, Mary Beth Seegars, Ralph D’Agostino, Lynne Wagner, W. Gregory Hundley

“…Trial registration #NCT01719562 ClinicalTrials.gov. Registered July 2, 2019—retrospectively registered.…”
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TEC-ADHERE: Real-World Persistence and Adherence on Dimethyl Fumarate in Patients with Relapsing–Remitting Multiple Sclerosis in the French OroSEP Patient-Support Program by Pierre Labauge, Alain Créange, Thibault Moreau, Jocelyne Nouvet-Gire, Bernard Pedespan, Olivier Heinzlef, Nathalie Texier, Marilyn Gros, Catherine Marti, Marta Ruiz, Mikel Martinez, Giovanni Castelnovo

“…Trial Registration ClinicalTrials.gov identifier, NCT04221191.…”
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Incidence of shoulder dislocations in the UK, 1995–2015: a population-based cohort study by Gary S Collins, Sarah E Lamb, Sally Hopewell, Daniel Prieto-Alhambra, Andrew Judge, Amar Rangan, Andrew J Carr, Jonathan L Rees, Nigel K Arden, Katherine Edwards, Tim A Holt, Anjali Shah, Antonella Delmestri, Rafael A Pinedo-Villanueva

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Suhexiang pill for acute ischemic stroke in real-world practice setting (SUNRISE): protocol of a multicenter registry by Xinxing Lai, Xuejiao Xiong, Qi Jia, Tingting Liu, Zhaowen Yang, Chi Zhang, Lingbo Kong, Kegang Cao, Ting Dong, Caixia Fang, Jianwen Ge, Li Dong, Zhitao Zong, Sisi Chen, Yuhong Ma, Xue Bai, Dahua Wu, Yao Xie, Mingyan Zhang, Yilong Wang, Guohui Jiang, Daqiao Song, Yanping Wang, Chunyan Gui, Qingwen Geng, Ying Gao, for the SUNRISE study investigators

“…Study registration This study was registered with the ClinicalTrials.gov (URL: https://clinicaltrials.gov/ , Unique identifier: NCT05833932).…”
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