Clinical Trials Committee -- An update by Helen Ramsdale

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Clinical Trials: New Developments by Louis-Philippe Boulet

“…Many Canadian researchers are leaders in international projects, including large scale clinical trials. There is, however, a need to develop a structure that could foster the collaboration of Canadian investigators in joint projects of this sort. …”
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Characteristics of COVID-19 clinical trials registered with ClinicalTrials.gov: cross-sectional analysis by Timothy F Platts-Mills, Christopher W Jones, Ashley L Woodford

“…Objectives To characterise current COVID-19-related research activities.Design Cross-sectional analysis.Setting Clinical trials registered with ClinicalTrials.gov testing interventions relevant to COVID-19.Data sources ClinicalTrials.gov was searched for COVID-19 and related terms to identify trials registered between 1 December 2019 and 1 May 2020 that test interventions related to the COVID-19 pandemic.Main outcome measures We classified trials according to intervention type, and report key trial characteristics including recruitment status, location, funder type, target enrolment number, intervention model (single group, randomised or sequential assignment) and projected completion date.Results Of the 630 identified clinical trials related to COVID-19, 509 (81%) involved the study of drugs or biological agents. …”
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Predicting accrual success for better clinical trial resource allocation by Sisi Ma, Yinzhao Wang, John Wagner, Steve Johnson, Serguei Pakhomov, Constantin Aliferis

Subjects: “…Clinical trial…”
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Experience in conducting clinical trials in Cienfuegos by Olga Lidia Cuevas Pérez, Diana Rosa Fernández Ruíz, Gredsy Escandón López, Mayra Quirós Enrique, Yuleidis García Rodríguez

“…<br /><strong>Objective:</strong> To describe the experience and development achived in Cienfuegos in conducting clinical trials. <br /><strong>Methods:</strong> it is a descriptive study on the clinical trials conducted in Cienfuegos from May 1992 to May 2016. …”
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Adaptive and Sequential Methods for Clinical Trials by Yichuan Zhao, Zhengjia Chen, Xuelin Huang, Mourad Tighiouart

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Discrepancies in safety reporting for chronic back pain clinical trials: an observational study from ClinicalTrials.gov and publications by Nick Boyne, Alison Duke, Jack Rea, Adam Khan, Alec Young, Jared Van Vleet, Matt Vassar

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Open challenges for the automatic synthesis of clinical trials by Olivia Sanchez-Graillet, David M. Schmidt, Christian Kullik, Philipp Cimiano

Subjects: “…Clinical trial synthesis…”
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A New Paradigm for Clinical Trials in Antibiotherapy? by Kevin B. Laupland, David N. Fisman

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The Clinical Trials of Mesenchymal Stromal Cells Therapy by Mohammad Reza Kouchakian, Neda Baghban, Seyedeh Farzaneh Moniri, Mandana Baghban, Shabnam Bakhshalizadeh, Vahid Najafzadeh, Zahra Safaei, Safoura Izanlou, Arezoo Khoradmehr, Iraj Nabipour, Reza Shirazi, Amin Tamadon

“…Many studies have been conducted on the application of MSCs as a new therapy, but it seems that a low percentage of them is related to clinical trials, especially completed clinical trials. …”
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Outcome differences by sex in oncology clinical trials by Ashwin V. Kammula, Alejandro A. Schäffer, Padma Sheila Rajagopal, Razelle Kurzrock, Eytan Ruppin

“…Abstract Identifying sex differences in outcomes and toxicity between males and females in oncology clinical trials is important and has also been mandated by National Institutes of Health policies. …”
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Mycobacterium tuberculosis: 2014 Clinical Trials in Review by Kevin B Laupland, Louis Valiquette

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Proceedings of clinical trials on bile tract cancer by XIONG Yichen, YANG Ziyi, SANG Yuer, GONG Wei

Subjects: “…|bile tract cancer(btc)|clinical trial|precision medicine…”
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Conducting clinical trials with self-collection of pharmacokinetic samples: Experience from an exploratory, phase 1, open-label trial of centanafadine SR in healthy individuals by Chelsea Ye, Tatiana Shablinski, Susan E. Shoaf, Chris Chung, Michelle Bullock

Subjects: “…Alternative clinical trial design…”
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Kinesiotherapy for Post-stroke Rehabilitation： Analysis of Characteristics of Clinical Trials in the Past 20 Years Based on Clinical Trials Registry Platform by WANG Hui, FENG Yuting, YU Yongpei, HU Chenhua, TAO Liyuan

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Gaps in the ethical governance of pharmaceutical clinical trials in Europe by Rosemarie D. L. C. Bernabe, Rosemarie D. L. C. Bernabe, Shereen A. Dawkins-Cox, Christine C. Gispen-de Wied

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Using Mathematical Modeling as a Resource in Clinical Trials by Evans K. Afenya

Subjects: “…clinical trials.…”
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WhatsApp and atopic dermatitis: a clinical trial by Thaís Braga Cerqueira, Renata Robl Imoto, Mariana Muzzolon, Vânia Oliveira de Carvalho

“…Methods: Researcher-blinded randomized controlled clinical trial. The experimental group (EG) received messages about AD and the control group (CG) about general health. …”
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Importance of clinical trials and contributions to contemporary medicine: commentary by Haofuzi Zhang, Xiaofan Jiang

Subjects: “…Clinical trial…”
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Clinical trials on carotenoids and vitamin mineral supplements in ophthalmology by A.A. Gvetadze, M.G. Rabadanova

“…Clinical trials on carotenoids and vitamin mineral supplements in ophthalmology. …”
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