Biomarkers in Adult Dermatomyositis: Tools to Help the Diagnosis and Predict the Clinical Outcome by Charles Cassius, Hélène Le Buanec, Jean-David Bouaziz, Reyhan Amode

“…Activity markers can be used to monitor disease activity in clinical trials and may also be useful in daily practice. …”
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Assessment of Chronic Pain in Children: Current Status and Emerging Topics by Tonya Mizell Palermo

“…Second, sensitivity of instruments within these domains is presented using data from clinical trials of psychological therapies aimed at treatment of chronic pain in children and adolescents. …”
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Brivaracetam to Treat Partial Onset Seizures in Adults by Dustin Latimer, David Le, Evan Falgoust, Patrick Ingraffia, Alaa Abd-Elsayed, Elyse M. Cornett, Rupin Singh, JooHee Choi, Giustino Varrassi, Adam M. Kaye, Alan D. Kaye, Latha Ganti

“…It was approved by the FDA in 2016 and has shown promising results with minimal adverse effect reactions in clinical trials. # Recent Findings Brivaracetam has been used in multiple clinical trials at various dosages in adults that have partial-onset seizures refractory to conventional treatment. …”
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Nicotine Has a Therapeutic Window of Effectiveness in a Drosophila melanogaster Model of Parkinson’s Disease by Brady T. Mannett, Braden C. Capt, Krista Pearman, Lori M. Buhlman, John M. VandenBrooks, Gerald B. Call

“…This therapeutic window of nicotine administration in this PD model fly may help to explain the lack of efficacy of nicotine in human clinical trials.…”
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Targeting the B-Cell Pathway in Lupus Nephritis: Current Evidence and Future Perspectives by Panagiotis Pateinakis, Athina Pyrpasopoulou

“…This review aims to expand on the proposed pathophysiologic mechanisms implicating the B-cell pathway in the pathogenesis of lupus nephritis and summarize current knowledge obtained from clinical trials introducing these biologics in its treatment. …”
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Outcome measures in vitiligo: A narrative review by K.B. Meghana, Anuradha Bishnoi, Davinder Parsad

“…Though there are many outcome measures, there is a lack of uniformity in reporting these across research papers and clinical trials making it challenging to interpret and compare the results. …”
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Artemether/Lumefantrine for the Treatment of P. malariae in a Patient on Hemodialysis by Rita Patrocínio-Jesus, João Cunha, Diva Trigo, Bárbara Flor-de-Lima, Patrícia Pacheco

“…There have been no clinical trials to assess the efficacy of this medication in patients with renal impairment. …”
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Conventional and complementary alternative medicine therapies for renal anemia: a literature review by Ching-Ming Lu, Ching-Ming Lu, Yuan-Hsuan Hsu, Yuan-Hsuan Hsu, I-Hsin Lin, Ko-Lin Kuo, Jian-Fu Liao, Hui-Fen Huang, Hui-Fen Huang, Ping-Hsun Lu, Ping-Hsun Lu

“…We conducted a comprehensive search across electronic databases including PubMed, Embase, Cochrane Library, Chinese National Knowledge Infrastructure, Airiti library, and Wanfang, to compile recent clinical trials and pilot studies on conventional and complementary alternative medicine approaches for renal anemia. …”
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Motor Imagery and Mental Practice in the Subacute and Chronic Phases in Upper Limb Rehabilitation after Stroke: A Systematic Review by Enrique Villa-Berges, Ana Alejandra Laborda Soriano, Orosia Lucha-López, José Miguel Tricas-Moreno, Mar Hernández-Secorún, Miguel Gómez-Martínez, César Hidalgo-García

“…We analysed a total of 11 randomized clinical trials, with moderate and high methodological quality according to the PEDro scale. …”
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Modern vaccines and coronavirus infections by Yu. A. Belikova, Yu. V. Samsonov, E. V. Abakushina

“…Some potential vaccine candidates have progressed to phase I and II clinical trials. In Russia, a vector vaccine based on adenovirus DNA, which has the SARS-CoV-2 virus gene embedded in it, is undergoing clinical trials.…”
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Antitumoral and Anti-inflammatory Roles of Somatostatin and Its Analogs in Hepatocellular Carcinoma by Argyrios Periferakis, Georgios Tsigas, Aristodemos-Theodoros Periferakis, Ioana Anca Badarau, Andreea-Elena Scheau, Mircea Tampa, Simona Roxana Georgescu, Andreea Cristiana Didilescu, Cristian Scheau, Constantin Caruntu

“…While the majority of these clinical trials exhibited minor to moderate success, some other studies were inconclusive or even reported negative outcomes. …”
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Rescue Therapy with a Proton Pump Inhibitor Plus Amoxicillin and Rifabutin for Helicobacter pylori Infection: A Systematic Review and Meta-Analysis by Xiaoqun Liu, Hui Wang, Zhifa Lv, Youhua Wang, Ben Wang, Yong Xie, Xiaojiang Zhou, Nonghua Lv

“…To conduct a systematic review and meta-analysis of clinical trials for eradication of Helicobacter pylori (H. pylori) that included a treatment arm with a proton pump inhibitor, rifabutin, and amoxicillin. …”
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Development of Carnivac-Cov vaccine against coronavirus infection (COVID-19) in carnivores by T. S. Galkina, A. A. Nesterov, A. V. Borisov, I. A. Chvala, A. V. Kononov

“…More than 330 animals (fur animals, cats, dogs) were involved in the preclinical and clinical trials. The trials have demonstrated that the vaccine is safe for target animals. …”
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Enteral L-Arginine and Glutamine Supplementation for Prevention of NEC in Preterm Neonates by M. S. El-Shimi, H. A. Awad, M. A. Abdelwahed, M. H. Mohamed, S. M. Khafagy, G. Saleh

“…This work is registered in ClinicalTrials.gov (ClinicalTrials.gov Identifier: NCT01263041).…”
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Efficacy and Acceptability of Orthokeratology for Slowing Myopic Progression in Children: A Systematic Review and Meta-Analysis by Daizong Wen, Jinhai Huang, Hao Chen, Fangjun Bao, Giacomo Savini, Antonio Calossi, Haisi Chen, Xuexi Li, Qinmei Wang

“…A systematic literature retrieval was conducted in MEDLINE, EMBASE, Cochrane Library, World Health Organization International Clinical Trials Registry Platform, and ClinicalTrials.gov. …”
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DPP-4 Inhibitors as Treatments for Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis by Qixian Wang, Min Long, Hua Qu, Rufei Shen, Rui Zhang, Jing Xu, Xin Xiong, Hui Wang, Hongting Zheng

“…Further optimized clinical trials are needed.…”
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MicroRNAs as Immunotherapy Targets for Treating Gastroenterological Cancers by Yixin Yang, Christopher Alderman, Ayoub Sehlaoui, Yuan Xiao, Wei Wang

“…Immunotherapy has been developed and underwent clinical trials, but displayed limited therapeutic benefit. …”
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Photodynamic therapy for the precise treatment of localized prostate cancer by Youcheng Xu, Qinyuan Tan, Chong Sun, Yuefeng Jia, Shengxian Li, Xuecheng Yang

“…We also reviewed the results of a few photosensitizers in these clinical trials. However, a few limitations and challenges regarding PDT for prostate cancer still exist. …”
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Umbilical Cord as Prospective Source for Mesenchymal Stem Cell-Based Therapy by Irina Arutyunyan, Andrey Elchaninov, Andrey Makarov, Timur Fatkhudinov

“…A review of preclinical studies and clinical trials using this cell type is performed. Prospects for the use of mesenchymal stem cells, derived from the umbilical cord, in cell transplantation are associated with the need for specialized biobanking and transplant standardization criteria.…”
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Early disease detection expert system development: primary machining software applications and dependences by A. S. Serobabov, E. V. Chebanenko, L. A. Denisova, T. S. Krolevets

“…The article observes descriptive statistics tools for the biomedical information processing, clinical trials data on the nonalcoholic fatty liver disease (NAFLD). …”
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