Extracorporeal Ultrasound-Guided High Intensity Focused Ultrasound: Implications from the Present Clinical Trials by Tinghe Yu, Xiao Fu

“…These implied that HIFU should be applied as an alternative at most occasions. The present clinical trials had defects making against the understating of HIFU.…”
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Heterogeneity of Treatment Effects of Laser Epilation on Pilonidal Disease Recurrence: A Randomized Clinical Trial by Katherine C. Bergus, MD, MPH, Carley Lutz, BS, Jennifer Cooper, PhD, Lindsey Asti, PhD, MPH, Lindsay Gil, MD, MPH, Cory Criss, MD, Katherine J. Deans, MD, MHSc, Peter C. Minneci, MD, MHSc

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Effect of Humulus lupulus L. (Hop) on Postmenopausal Sexual Dysfunction: A Randomized Clinical Trial by Zahra Vahedpoorfard, Samira Ferdosi, Habibollah Rahimi, Hossein Motedayyen

“…In the current randomized clinical trial, study populations consisted of 63 postmenopausal women who were randomly categorized into two groups. …”
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The Effect of External Cold and Vibration on Infiltration-Induced Pain in Children: A Randomized Clinical Trial by Reihaneh Faghihian, Mona Esmaeili, Hossein Asadi, Mohammad Hossein Nikbakht, Fateme Shadmanfar, Mehdi Jafarzadeh

“…Thirty children aged 6–12 years who required profound restoration of deciduous or permanent first molars were recruited in this randomized double-blind clinical trial. The anesthetic gel and BUZZY device were used in half of the children’s jaws, and the anesthetic gel and the cold alone were used in the other half of the jaws. …”
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Corrigendum to “The “L-Sandwich” Strategy for True Coronary Bifurcation Lesions: A Randomized Clinical Trial” by Quan Guo, Liang Peng, Lixin Rao, Cao Ma, Kang Zhao, Zhenzhou Zhao, Haiyu Tang, Muwei Li

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The roadmap to integrate diversity, equity, and inclusion in hematology clinical trials: an American Society of Hematology initiative by Alice Kuaban, Alysha K. Croker, Jeffrey Keefer, Leonard A. Valentino, Barbara E. Bierer, Stephen Boateng, Donna DiMichele, Patrick Fogarty, C. Michael Gibson, Anna M. Hood, Lloryn Hubbard, Antonella Isgrò, Karin Knobe, Leslie Lake, Iman Martin, Michel Reid, Jonathan C. Roberts, Wendy Tomlinson, Lanre Tunji-Ajayi, Harriette G.C. Van Spall, Caroline Voltz-Girolt, Allison P. Wheeler, Alan E. Mast, Stephanie Seremetis

“…Abstract: Clinical trial design for classical hematologic diseases is difficult because samples sizes are often small and not representative of the disease population. …”
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Pegilated interferon alpha 2b «Pegaltevir» chronic hepatitis C treatment (randomized clinical trial) by Marina V. Mayevskaya, Ye. N. Bessonova, P. O. Bogomolov, N. I. Geyvandova, K. V. Zhdanov, V. G. Morozov, V. D. Pasechnikov, I. Yu. Khomenko, A. V. Yagoda, V. T. Ivashkin

“…These qualities formed the basis for development of the Russian pegilated interferon-alpha 2b (Pegaltevir®, LLC «FARMAPARK», Russia) and carrying out doublestaged randomized open clinical trial: study of safety, tolerability and pharmacokinetics of Pegaltevir® at single injection of increasing doses in various groups of healthy volunteers - the I stage; studying of efficacy and safety of Pegaltevir® in comparison to PegIntron® (Schering-Plough, USA) at CHC as a part of double antiviral therapy with ribavirin (Rebetol®, Schering-Plough, USA) - the II stage. …”
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Protein kinase inhibitors as targeted therapy for glioblastoma: a meta-analysis of randomized controlled clinical trials by José Pinto-Fraga, Celia García-Chico, Simone Lista, Pedro Miguel Lacal, Giuseppe Carpenzano, Maurizio Salvati, Alejandro Santos-Lozano, Grazia Graziani, Claudia Ceci

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Advantages and disadvantages of coronary drug-eluting stent: a 23-year journey of randomized clinical trials by Alfredo E. Rodriguez, Juan Mieres, Juan M. Rokos

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The Effect of auriculotherapy on sleep quality in children with attention deficit hyperactivity disorder: a randomized clinical trial by Laleh Mohammadi, Zahra Tagharrobi, Khadijeh Sharifi, Zahra Sooki, Mohammad Zare, Fatemeh Zare Joshaghani

“…Materials and methods This clinical trial was conducted in children with ADHD in Kashan, Iran, 2021–2022. …”
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Metformin versus insulin in glycemic control in pregnancy (MevIP): a randomized clinical trial protocol by Carolina Freitas Alves Amaral-Moreira, Daiane Sofia Morais Paulino, Belmiro G. Pereira, Patricia Moretti Rehder, Fernanda G. Surita

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Risk Factors of Delirium Following Reconstructive Surgery for Head and Neck Tumors: A Retrospective Clinical Trial by Li L, Zhang L, Wu X, Zeng Z

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Evaluation of in-office tooth whitening treatment with violet LED: protocol for a randomised controlled clinical trial by Lara Jansiski Motta, Anna Carolina Ratto Tempestini Horliana, Sandra Kalil Bussadori, Maria Fernanda Setúbal Destro Rodrigues, Ana Eliza Castanho Garrini dos Santos, Marcelo Mendes Pinto, Dácio Antonio Pantano Junior, Aldo Brugnera Jr, Fátima Antonia Aparecida Zanin

“…This study describes a protocol for the first randomised controlled clinical trial to compare the effects of the two methods.Methods and analysis Eighty patients will be divided into four groups: G1 violet LED; G2 violet LED +35% carbamide peroxide; G3 35% H2O2 and G4 violet LED +gingivoplasty. …”
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Impact of Online Stress Management Training Program on the Sexual Function of Perimenopausal Women: A Clinical Trial by Leila Neisani Samani, Shima Arjmand, Naeimeh Seyedfatemi, Shima Haghani

“…Materials & Methods This is a clinical trial with a pre-test/post-test design that was conducted on 50 perimenopausal women aged 40-50 referring to Sohrab Ali Bakhshi comprehensive health center in Shahriar town, Tehran, Iran, in 2022, who were selected using a continuous sampling method. …”
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Patient-centered outcomes for clinical trials in chronic rhinosinusitis with or without nasal polyps and allergic fungal rhinosinusitis by Brittany Klooster, Kaitlin Chatterton, Nazifa Ibrahim, Madison C. Bernstein, Alan L. Shields, Veleka Allen

“…Methods Literature, clinical trial, and product label reviews were conducted to identify symptoms, impacts, and COAs used to assess CRSwNP, CRSsNP, and AFRS patient experiences in clinical trials. …”
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Multicenter Randomized Clinical Trial of Brief Psychotherapy versus Usual Treatment for Common Mental Disorders in Adults by Marco A. Luengo-Castro, Javier Fernández-Méndez, José M. García-Montes, Pedro J. Caunedo-Riesco, Juan M. García-Haro, Begoña Braña-Menéndez, Dolores González-Díaz, Andrés Cabero-Álvarez, Marcelino Cuesta-Izquierdo

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The Effect of Vitamin D3 on the Alignment of Mandibular Anterior Teeth: A Randomized Controlled Clinical Trial by Ali Al-Attar, Mushriq Abid

“…The trial was registered with ClinicalTrials.gov on 12th April 2021 (registration number: NCT04837781).…”
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A systematic review on malaria and Tuberculosis (TB) vaccine challenges in sub-Saharan African clinical trials. by Maonezi Abas Hamisi, Nur Ain Mohd Asri, Aini Syahida Mat Yassim, Rapeah Suppian

“…In both cases, the major challenges in sub-Saharan African clinical trials were immunogenicity and efficacy, rather than safety.…”
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The Effectiveness of Fluorescent Light Energy as Adjunct Therapy in Canine Deep Pyoderma: A Randomized Clinical Trial by Andrea Marchegiani, Alessandro Fruganti, Andrea Spaterna, Matteo Cerquetella, Adolfo M. Tambella, Susan Paterson

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Impact of telephone follow-up on COPD outcomes in pulmonary rehabilitation patients: A randomized clinical trial by Stefanie Tonguino Rosero, Juan Carlos Ávila Valencia, Jhonatan Betancourt Peña

“… # Methods Double-blind randomized controlled clinical trial in patients with COPD in a PR program in Cali-Colombia, allocation by randomization tables. …”
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