Outcomes and safety of mechanical thrombectomy, alteplase, and conventional medical care in the treatment of acute M2 segment middle cerebral artery occlusion: a comparative study by Eman M. Khedr, Ahmed Elbassiouny, Mahmoud Nageeb, Ahmed Aly, Khalid O. Mohamed, Nourelhoda A. Haridy

“…Trial registration: This study was prospectively registered in the clinical trial with ClinicalTrials.gov ID (NCT05091320). …”
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Efficacy of Diltiazem for the Control of Blood Pressure in Puerperal Patients with Severe Preeclampsia: A Randomized, Single-Blind, Controlled Trial by Gilberto Arias-Hernández, Cruz Vargas-De-León, Claudia C Calzada-Mendoza, María Esther Ocharan-Hernández

“…A randomized, single-blind longitudinal clinical trial of 42 puerperal patients with severe preeclampsia was carried out. …”
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Telemedicine in home enteral nutrition: a structured survey exploring acceptability, preferences and experiences among patients by Ya Ma, Xuemei Li, Qian You, Wen Hu, Zhiyong Rao, Yanru Deng, Yiyao Zhang, Lei Shi

“…Trial registration The study was registered in the Chinese Clinical Trial Registry (clinical registration number: ChiCTR2100053762, registration date: 2021–11-29).…”
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Effect of endoscopic sinus surgery on eustachian tube function in adult patients with chronic rhinosinusitis by Mahmoud Atef Abdelghaffar Youssef, Nassim Talaat Nassim, MohamedNourEddin Bashir Alkeeb, Tareq Muhammad Algarf

“…Method This non-randomized clinical trial study was conducted at the Otorhinolaryngology department, the Faculty of Medicine, Cairo University, on 40 patients > 18 years old, suffering from CRS with or without sinonasal polyposis who are indicated for endoscopic sinus surgery (ESS) and were recruited from Otorhinolaryngology department’s outpatient clinic in the period from November 2022 to June 2023. …”
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Extracellular Vesicles Released from Neprilysin Gene-Modified Human Umbilical Cord-Derived Mesenchymal Stem Cell Enhance Therapeutic Effects in an Alzheimer’s Disease Animal Model... by HyeJu Jeong, Ok Joon Kim, Seung-Hun Oh, Sanghoon Lee, Han A. Reum Lee, Kee Ook Lee, Boo-Yong Lee, Nam Keun Kim

“…Alzheimer’s disease (AD) animal studies have reported that mesenchymal stem cells (MSCs) have therapeutic effects; however, clinical trial results are controversial. Neprilysin (NEP) is the main cleavage enzyme of β-amyloid (Aβ), which plays a major role in the pathology and etiology of AD. …”
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Daily versus three-times-weekly azithromycin in Chinese patients with non-cystic fibrosis bronchiectasis: protocol for a prospective, open-label and randomised controlled trial by Jing Li, Fei Chen, Wei Xiao, Feng Li, Lan Chen, Ting He, Yanxiong Mao, Aiping Zou, Bo Fan, Weihao Ni, Huimin You, Wenjiang Fu

“…This protocol describes a head-to-head clinical trial designed to compare the efficacy of two dosing regimens of azithromycin in Chinese NCFB population.Methods and analysis This prospective, open-label and randomised controlled trial will be conducted in the First People’s Hospital of Jiashan, China. …”
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Pain Reduction in Patellofemoral Knee Patients During 3-Month Intervention with Biomechanical and Sensorimotor Foot Orthoses: A Randomized Controlled Clinical Study by Steven Simon, Andreas Heine, Jonas Dully, Carlo Dindorf, Oliver Ludwig, Michael Fröhlich, Stephan Becker

“…This trial was registered in the WHO International Clinical Trials Registry Platform (ICTRP) and German Clinical Trials Register (DRKS00035082).…”
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Synergistic effects of PGPRs and fertilizer amendments on improving the yield and productivity of Canola (Brassica napus L.) by Haji Muhammad, Muhammad Ijaz, Abdul Sattar, Sami Ul-Allah, Ahmad Sher, Muhammad Asif, Muhammad Dilshad, Khalid Mahmood, Muhammad Waheed Riaz, Muhammad Saqlain Zaheer, Muhammad Rizwan, Salim Manoharadas

“…Combining PGPRs with fertilizers for canola enhances nutrient efficiency, promotes sustainable growth, and boosts stress resilience, addressing agricultural and environmental challenges. Clinical trial number Not Applicable.…”
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Anti-Idiotypic Antibody as a Booster Vaccine Against Respiratory Syncytial Virus by Shreya Mukhopadhyay, Ioannis Manolaridis, Christopher Warren, Aimin Tang, Gregory O’Donnell, Bin Luo, Ryan P. Staupe, Kalpit A. Vora, Zhifeng Chen

“…It is the precursor for MK1654 (clesrovimab), which successfully completed a Phase III clinical trial. <b>Methods:</b> In this study, we isolated two anti-IDs, 1A6 and 1D4, targeting RB1 CDR regions, demonstrating that 1A6 competes fully with RSV F in binding to RB1. …”
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From strain to strength: a yearlong study on the transformative influence of inner engineering online program on mental well-being by Ashwin Swaminathan, Braiden DeSchryver, Akila Rayapuraju, Julianna Barbaro, Hibiki Orui, Balachundhar Subramaniam, Preeti Upadhyay Reed

“…These benefits were sustained for at least a year with continued practice, suggesting that this practice is an effective path to maintaining general well-being.Clinical trial registrationClinicalTrials.gov, trial identification number NCT04189146.…”
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Comparative effective dose of ciprofol and propofol in suppressing cardiovascular responses to tracheal intubation by Min Liao, Xiao-Ru Wu, Jia-Ning Hu, Xing-Zhou Lin, Tang‑yuan‑meng Zhao, Hu Sun

“…Group C experienced significantly less injection pain (p = 0.001), although the incidence of other adverse effects was not statistically different between groups (p > 0.05). Clinical Trial Registration: hppts://ClinicalTrials.gov; Identifier: NCT06095570(18/10/2023).…”
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Surgical techniques and prognostic nomogram for patients with supravalvular aortic stenosis by Yuekun Sun, Lizhi Lv, Xinyue Lang, Aihua Zhi, Simeng Zhang, Cheng Wang, Qiang Wang

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Metaverse Clinic for Pregnant Women With Subclinical Hypothyroidism: Prospective Randomized Study by Yuanyuan Zheng, Yizhen Chen, Yan Chen, Liang Lin, Ting Xue, Chuhui Chen, Junping Wen, Wei Lin, Gang Chen

“…Trial RegistrationChinese Clinical Trial Registry ChiCTR2300076803; https://www.chictr.org.cn/showproj.html?…”
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Antimicrobial resistance, virulence gene profiling, and genetic diversity of multidrug-resistant Pseudomonas aeruginosa isolates in Mazandaran, Iran by Ghazaleh Elahi, Hamid Reza Goli, Morvarid Shafiei, Vajihe Sadat Nikbin, Mehrdad Gholami

“…The substantial genetic diversity observed among isolates suggests that P. aeruginosa in this region may rapidly evolve, necessitating ongoing surveillance and more targeted antimicrobial strategies. Clinical trial number Not applicable.…”
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Analysis of antimicrobial resistance and clinical features of Staphylococcus aureus-infected bone and joint infections in children by Xingguang Chen, Ting Zhuang, Chengda Zou, Yao Liu, Qian Sun, Mengxia Li, Wen Zheng, Chaochen Zhao, Xiaodong Wang

“…Further studies are required to validate these findings before they can be widely applied. Clinical trial number Not applicable.…”
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Intermittent enteral nutrition shortens the time to achieve nutritional goals in critically ill patients by Ondrej Hrdy, Kamil Vrbica, Jaroslav Duba, Martin Slezak, Eva Strazevska, Viktor Agalarev, Milos Duba, Radka Stepanova, Adam Svobodnik, Roman Gal

“…A prospective, randomized, single-center clinical trial was conducted in four intensive care units in the Czech Republic. …”
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Influence of strength and power training on the rate of force development, peak force and functional mobility in elderly people with Parkinson's disease: a randomized controlled tr... by Késia Maísa do Amaral Felipe, Késia Maísa do Amaral Felipe, Patrícia de Aguiar Yamada, Tamires Meneghetti, Flávia Roberta Faganello-Navega, Flávia Roberta Faganello-Navega

“…ObjectiveTo analyze the influence of lower limb muscle strength and muscle power training on rate of force development (RFD) and peak force (PF) in elderly people with Parkinson's disease (PD), as well as the effect of these training sessions influence on the functional mobility (FM) of this population.MethodsThis was a randomized controlled clinical trial and registered on the virtual platform for registration of experimental and non-experimental studies “Registro Brasileiro de Ensaios Clínicos (ReBEC)”. …”
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Translation of a Diabetes Remission Service into Australian Primary Care: Findings from the Evaluation of DiRECT-Australia by Ritesh Chimoriya, Kimberly Mitlehner, Chee L. Khoo, Uchechukwu Levi Osuagwu, Russell Thomson, Lei Si, Michael Lean, David Simmons, Milan K. Piya

“…The Diabetes Remission Clinical Trial (DiRECT) study demonstrated that an intensive and structured weight management program in UK primary care resulted in high rates of diabetes remission in adults with recent onset type 2 diabetes mellitus (T2DM). …”
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Preliminary efficacy of eye movement desensitization and reprocessing for children aged 1.5–8 years with PTSD: a multiple baseline experimental design (N = 19) by Carlijn de Roos, Julia Offermans, Samantha Bouwmeester, Ramón Lindauer, Frederike Scheper

“…Further trials are warranted.Trial Registration: International Clinical Trial Registry Platform (before National Trial Register, trial search/who/int: identifier: NL8426, EMDR for young children with PTSD).…”
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Effects of Lactobacillus gasseri OLL2716 on Helicobacter pylori-Associated Dyspepsia: A Multicenter Randomized Double-Blind Controlled Trial by Atsushi Takagi, Hidetaka Yanagi, Hideki Ozawa, Naomi Uemura, Shigemi Nakajima, Kazuhiko Inoue, Takashi Kawai, Toshihiro Ohtsu, Yasuhiro Koga

“…This study was registered at the University Hospital Medical Network Clinical Trial Registry (UMIN000016746).…”
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