Efficacy of acupuncture for primary osteoporosis: a systematic review and meta-analysis of randomized controlled trials by Tianyi Ma, Tiantian Zhang, Le Zhang, Haoming Zhao, Ke Liu, Jianjun Kuang, Liang Ou

“…Methods We searched for potentially relevant studies in PubMed, Web of Science, Embase, Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, China Biology Medicine disc, Wanfang database and ClinicalTrials.gov up to December 20, 2024. Randomized controlled trials investigating treatment of POP for which acupuncture was administered as a stand-alone treatment or combined with conventional medicine compared to conventional medicine or placebo, were included. …”
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The effect of the APOE4 genotype on physiological and cognitive health in randomised controlled trials with an exercise intervention: a systematic review and meta-analysis by Felicity S. E. Spencer, Richard J. Elsworthy, Leigh Breen, Jon R. B. Bishop, Connor Dunleavy, Sarah Aldred

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Effectiveness of a Dyadic Technology–Enhanced Home-Based Horticultural Therapy on Psychosocial Well-Being Among People With Dementia and Their Family Caregivers: Multimethods Pilot... by Patrick Pui Kin Kor, Justina Yat Wa Liu, Arkers Kwan Ching Wong, Alex Pak Lik Tsang, Han Zhi Tan, Daphne Sze Ki Cheung, Humphrey Kwong Wai Leung, Frances Kam Yuet Wong

“…Trial RegistrationClinicalTrials.gov NCT05577975; https://clinicaltrials.gov/study/NCT05577975…”
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The impact of universal mental health screening on stigma in primary schools by Annabel Songco, Deanna A. Francis, Emma A. McDermott, Chloe Y. S. Lim, Abigail Allsop, Joseph Croguennec, Gemma Sicouri, Andrew Mackinnon, Jennifer L. Hudson

“…Trial registration Australian and New Zealand Clinical Trials Registry (ACTRN12622001114730) https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?…”
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Shenkang injection for the treatment of acute kidney injury: a systematic review and meta-analysis by Shengchun Liao, Yurou Chen, Shuting Wang, Chen Wang, Chaoyang Ye

“…Additional rigorous clinical trials will be necessary in the future to thoroughly evaluate and establish the effectiveness of SKI in the treatment of AKI.…”
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Barriers to healthcare professionals screening, recognizing, and managing delirium in the adult patients receiving specialist palliative care: a mixed-methods systematic review by Fang Qian, Danyang Yao, Huanhuan Shi, Tao-Hsin Tung, Dongjun Bi

“…Literature was sourced from PubMed, Web of Science, Embase, CINAHL, The Cochrane Library, and Clinical Trials databases from their inception to November 16, 2024, without language restrictions. …”
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Plain Language Summary of Publication: The ProLOGUE study investigating brodalumab in people with plaque psoriasis by Shinichi Imafuku, Chika Ohata, Masaru Honma, Hidehisa Saeki, Yoko Mizutani, Takuya Miyagi, Kenta Murotani, Yasumasa Kanai

“…Trial registration: You can read more about the ProLOGUE study on the following website: Japan Registry of Clinical Trials ( https://jrct.niph.go.jp/en-latest-detail/jRCTs031180037 ; jRCTs031180037). …”
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Association between terminal pleural elastance and radiographic lung re-expansion after therapeutic thoracentesis in patients with symptomatic pleural effusion: a post-hoc analysis... by Fabien Maldonado, Michael Lester, Otis B Rickman, Lance J Roller, Sameer K Avasarala, James M Katsis, Robert J Lentz

“…Clinical management of patients with recurrent symptomatic pleural effusions guided by manometry rather than post-thoracentesis imaging might produce better outcomes, which should be investigated by future clinical trials.Trial registration number NCT02677883; Post-results.…”
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Comparing physiological and psychological effects of virtual reality vs. traditional high-intensity interval training in healthy individuals: results from a preliminary pilot rando... by Jonathan Robinson, Mohammad Haziq Bin Abdul Razak

“…Trial registration ClinicalTrials.gov, NCT06420414. Registered 20 May 2024 — retrospectively registered, https://clinicaltrials.gov/study/NCT06420414…”
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The use of methylene blue in adult patients with septic shock: a systematic review and meta-analysis by Ka Ting Ng, Pei En Kwok, Wei En Lim, Wan Yi Teoh, Mohd Shahnaz Hasan, Mohd Fitry Zainal Abidin

“…Methods: Databases of MEDLINE, EMBASE, and CENTRAL were searched from their inception date until October 2023. Randomized Clinical Trials (RCT) comparing methylene blue and placebo in adults with septic shock were included. …”
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The potential of gardening and other plant‐related interventions to reduce symptoms of depression: A systematic review of non‐randomized controlled trials and uncontrolled studies... by Claudio D. Rosa, Talisson S. Chaves, Silvia Collado, Lincoln R. Larson, KangJae Jerry Lee, Christiana C. Profice

“…To complement previous work, we searched the databases MEDLINE, PsycArticles, SCOPUS, Google Scholar, and ClinicalTrials.gov and identified 30 non‐RCTs (n = 1063 participants; all adults) and 32 uncontrolled studies (n = 517 participants; only one study included 6 young people) examining the effects of horticultural interventions on depression. …”
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Protocol paper: randomized controlled trial of the smart online-to-offline model development for chronic diseases management through digital health in real world setting by Jae Eun Shin, Juho Choi, Heejung Lee, Suk-Won Lee, Juhwan Oh

“…Trial registration This study is registered at ClinicalTrials.gov of the US National Library of Medicine. …”
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Brodalumab: Six-Year US Pharmacovigilance Report by Mark G. Lebwohl, John Y. Koo, April W. Armstrong, Bruce E. Strober, Soo Han Yoon, Nicole N. Rawnsley, Earl L. Goehring, Gina D. Mangin, Abby A. Jacobson

“…Conclusion Pharmacovigilance data throughout 6 years are consistent with the safety profile of brodalumab established in clinical trials and previous US pharmacovigilance reports, with no completed suicides and a low fungal infection rate. …”
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The Cost-effectiveness of Celecoxib versus Non-steroidal Anti-inflammatory Drugs plus Proton-pump Inhibitors for Treating Osteoarthritis in Algeria by Nadir Hammoumraoui, Sid Ahmed Kherraf, Joaquin Mould-Quevedo, Tarek A. Ismail

“…Conditional probabilities were obtained from published clinical trials; effectiveness measure was quality-adjusted life years (QALYs) gained/patient. …”
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To remove or to replace traditional electronic games? A crossover randomised controlled trial on the impact of removing or replacing home access to electronic games on physical act... by Anne J Smith, Leon M Straker, Rebecca A Abbott

“…Parents can be advised that replacing sedentary electronic games with active electronic games is likely to have the same effect as removing all electronic games.Trial Registration Australia and New Zealand Clinical Trials Registry (ACTRN 12609000279224)…”
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A Systems-Based Analysis of the CardioMEMS HF Sensor for Chronic Heart Failure Management by Jeffrey S. Tran, Aaron M. Wolfson, Daniel O’Brien, Omid Yousefian, David M. Shavelle

“…Hemodynamic-guided therapy using the CardioMEMS™ system has been shown to reduce heart failure hospitalization (HFH) in both clinical trials and real-world settings. However, the CardioMEMS system requires input from multiple independent elements to achieve its effect, and no studies have been done to investigate those elements. …”
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Non-inferiority study to compare the efficacy of relugolix with dienogest for endometriosis-associated pain and usefulness of administering relugolix prior to dienogest (READY stud... by Fuminori Taniguchi, Motoko Fukui, Yutaka Osuga, Tasuku Harada, Jo Kitawaki

“…Trial registration Japan Registry of Clinical Trials ID jRCTs061230064. Registered on 29 September 2023.…”
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A 16-week randomized controlled trial of a fish oil and whey protein-derived supplement to improve physical performance in older adults losing autonomy-A pilot study. by Anne-Julie Tessier, Julia Lévy-Ndejuru, Audrey Moyen, Marissa Lawson, Marie Lamarche, Joseé A Morais, Amritpal Bhullar, Francis Andriamampionona, Vera C Mazurak, Stéphanie Chevalier

“…<h4>Trial registration</h4>ClinicalTrials.gov NCT04454359.…”
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Comparison of Hydrus and iStent microinvasive glaucoma surgery implants in combination with phacoemulsification for treatment of open-angle glaucoma: systematic review and network... by Xiaoyu Wang, Rongrong Hu, Dongyu Guo, Nan Hong, Xiuyuan Xuan

“…Objectives To compare the efficacy and safety of two Schlemm’s canal-based microinvasive glaucoma surgery (MIGS) devices, the Hydrus Microstent and the iStent Trabecular Bypass combined with phacoemulsification for treatment of open-angle glaucoma.Design Systematic review and network meta-analysis.Methods Literature searches were conducted on PubMed, Web of Science, Cochrane Library and ClinicalTrials.gov to identify randomised controlled trials (RCTs) assessing the Hydrus or the iStent implantation combined with phacoemulsification for treatment of open-angle glaucoma until September 2020. …”
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Effects of specific inspiratory muscle training combined with whole-body endurance training program on balance in COPD patients: Randomized controlled trial. by Bilel Tounsi, Amal Acheche, Thierry Lelard, Zouhair Tabka, Yassine Trabelsi, Said Ahmaidi

“…<h4>Trial registration</h4>The trial registry name: Clinical Trials; Registration number: NCT04084405; URL: https://clinicaltrials.gov/ct2/show/NCT04084405.…”
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