Effects of the Use of Non-Calcium Phosphate Binders in the Control and Outcome of Vascular Calcifications: A Review of Clinical Trials on CKD Patients by Piergiorgio Bolasco

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Subcutaneous sarilumab for the treatment of hospitalized patients with moderate to severe COVID19 disease: A pragmatic, embedded randomized clinical trial. by Westyn Branch-Elliman, Ryan Ferguson, Gheorghe Doros, Patricia Woods, Sarah Leatherman, Judith Strymish, Rupak Datta, Rekha Goswami, Matthew D Jankowich, Nishant R Shah, Thomas H Taylor, Sarah T Page, Sara J Schiller, Colleen Shannon, Cynthia Hau, Maura Flynn, Erika Holmberg, Karen Visnaw, Rupali Dhond, Mary Brophy, Paul A Monach

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Sublingual Sufentanil vs. Intravenous Fentanyl for the Treatment of Acute Postoperative Pain in the Ambulatory Surgery Center: A Randomized Clinical Trial by Aaron Berg, Jason Habeck, Michael Strigenz, Jonah Pearson, Alexander Kaizer, Jacob Hutchins

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Early empiric anti-Mycobacterium tuberculosis therapy for sepsis in sub-Saharan Africa: a protocol of a randomised clinical trial by Mark Conaway, David R Boulware, Scott K Heysell, Stellah G Mpagama, Christopher C Moore, Alphonce Liyoyo, Conrad Muzoora, Catherine Gitige, Bibie Said, Edwin Nuwagira, Rinah Arinaitwe, Rhina Mushagara, Peter Buzaare, Anna Chongolo, Samuel Jjunju, Precious Twesigye, Megan Null, Tania A Thomas

“…We will also present our findings to the Community Advisory Boards that we convened during study preparation.Trial registration number ClinicalTrials.gov (NCT04618198).…”
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Current Molecular Targeted Therapy in Advanced Gastric Cancer: A Comprehensive Review of Therapeutic Mechanism, Clinical Trials, and Practical Application by Kaichun Li, Jin Li

“…Unfortunately, none of the EGFR targeting antibodies (cetuximab or panitumumab), VEGF targeting monoclonal antibodies (bevacizumab), mTOR inhibitor (everolimus), or HGF/MET pathway targeting drugs has a significant survival benefit. Many other clinical trials based on molecular markers are underway. …”
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Effects of a cardiopulmonary rehabilitation programme on submaximal exercise in Tunisian patients with long-COVID19: A randomized clinical trial by Rania Kaddoussi, Hadhemi Rejeb, Amine Kalai, Eya Zaara, Naceur Rouetbi, Zohra Ben Salah Frih, Piotr Zmijewski, Helmi Ben Saad

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Comment on: Effect of combined training on body image, body composition and functional capacity in patients with breast cancer: controlled clinical trial by Piyush Bharadwaj, Divya Khati, Simran Sunil Khutarkar, Sweta Verma

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A Vaginal Inlay for Reduction of Stress Urinary Incontinence: Outcome of a Randomized Clinical Trial and Four User Acceptance Studies by Aino Fianu Jonasson, Karin Bryder, Elisabeth Sthengel

“…A multicenter, randomized, controlled clinical trial and four postmarket user acceptance investigations were carried out to document the safety, performance, and user acceptance of Efemia Bladder Support, a novel vaginal inlay for the temporary reduction of stress urinary incontinence (SUI). …”
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Efficacy and Safety of a Novel Herbal Medicine in the Treatment of Irritable Bowel Syndrome: A Randomized Double-Blinded Clinical Trial by Ghasem Bordbar, Mohammad Bagher Miri, Mahmoud Omidi, Saeed Shoja, Malihe Akhavan

“…The present study was a randomized double-blind clinical trial with parallel groups in Iran. Patients in the control arm received three tablets of 10 mg hyoscine butylbromide daily for two weeks, and the intervention arm was daily treated with two 250 mg softgel capsules containing 180 mg of essential oils of ZM, AG, and TA for two weeks. …”
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Viable Extreme Preterm Birth and Some Neonatal Outcomes in Double Cerclage versus Traditional Cerclage: A Randomized Clinical Trial by Farzaneh Broumand, Fatemeh Bahadori, Tahereh Behrouzilak, Zahra Yekta, Farkhondeh Ashrafi

“…The pregnant women at higher risk of preterm labor, referred to the perinatal clinic of Kosar University Hospital in Urmia district of Iran, were enrolled into a parallel randomized clinical trial. In the investigational arm of the clinical trial, a double cervical cerclage procedure was performed addition to McDonald cerclage. …”
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Phantom motor execution as a treatment for phantom limb pain: protocol of an international, double-blind, randomised controlled clinical trial by Brian E McGuire, Lina Bunketorp-Käll, Eva Lendaro, Liselotte Hermansson, Helena Burger, Corry K Van der Sluis, Monika Pilch, Katarzyna Kulbacka-Ortiz, Ingrid Rignér, Anita Stockselius, Lena Gudmundson, Cathrine Widehammar, Wendy Hill, Sybille Geers, Max Ortiz-Catalan

“…Here we present the study protocol for an international (seven countries), multicentre (nine clinics), double-blind, randomised controlled clinical trial to assess the effectiveness of PME in alleviating PLP.Methods and analysis Sixty-seven subjects suffering from PLP in upper or lower limbs are randomly assigned to PME or phantom motor imagery (PMI) interventions. …”
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Anaesthetic efficacy of intraligamentary injection compared to incisive nerve block using 3% mepivacaine hydrochloride: a randomized clinical trial by Suzan Salem, Islam Saad, Ramy Elmoazen, Ghada Amin Khalifa

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Virtual reality-based cognitive–behavioural therapy for the treatment of anxiety in patients with acute myocardial infarction: a randomised clinical trial by Jiajun Weng, Junbo Ge, Jiajia Liu, Juying Qian, Xiao Huang, Yuanyuan Li, Juan Peng, Yan'e Lu, Dong Huang, Pingyuan Yang, Shikun Xu, Lihua Guan, Qibing Wang, Zexin Zhao, Yabin Wei

“…Providing timely and easily accessible psychological interventions using virtual reality-based cognitive–behavioural therapy (VR-CBT) could potentially improve both acute and long-term symptoms affecting their mental health.Aims We aim to examine the effectiveness of VR-CBT on anxiety symptoms in patients with AMI who were admitted to the intensive care unit (ICU) during the acute stage of their illness.Methods In this single-blind randomised clinical trial, participants with anxiety symptoms who were admitted to the ICU due to AMI were continuously recruited from December 2022 to February 2023. …”
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Effectiveness and Safety of Using Standardized Treatment Protocols for Hypertension Compared to Usual Care: A Meta‐Analysis of Randomized Clinical Trials by Gautam Satheesh, Rupasvi Dhurjati, Vivekanand Jha, Aletta E. Schutte, Bolanle Banigbe, Dorairaj Prabhakaran, Andrew E. Moran, Abdul Salam

“…We conducted a systematic review of randomized clinical trials (RCTs) among adults with hypertension, comparing hypertension STPs (intervention) with usual care (comparator) for effects on BP. …”
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A randomized clinical trial comparing retention of complete dentures and oral health quality of life of patients with conventional and bioelectric impressions by Sapna Rani, Pankaj Dhawan, Vidushi Saxena

“…Conclusions: Although, there was no significant difference in retention and OHRQoL between both groups. However, more clinical trials with large samples and longer follow-ups are required to reach a conclusive result.…”
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The Effect of a Combination of Vibration and External Cold on Pain Caused during Vaccine Injection in Infants: A Randomized Clinical Trial by Zahra Unesi, Zahra Amouzeshi, Javad Jamavar, Fatemeh Mahmoudzadeh Zarandi

“…Methods. In this clinical trial, 80 eligible infants were selected from the infants referred to a health center as per the inclusion criteria. …”
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The Use of Green Coffee Extract as a Weight Loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials by Igho Onakpoya, Rohini Terry, Edzard Ernst

“…The purpose of this paper is to assess the efficacy of green coffee extract (GCE) as a weight loss supplement, using data from human clinical trials. Electronic and nonelectronic searches were conducted to identify relevant articles, with no restrictions in time or language. …”
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Use of Condition-Specific Patient-Reported Outcome Measures in Clinical Trials among Patients with Wrist Osteoarthritis: A Systematic Review by Steven M. McPhail, Karl S. Bagraith, Mandy Schippers, Paula J. Wells, Anna Hatton

“…This paper aimed to identify condition-specific patient-reported outcome measures used in clinical trials among people with wrist osteoarthritis and summarise empirical peer-reviewed evidence supporting their reliability, validity, and responsiveness to change. …”
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A randomized double-blind active-controlled clinical trial on the efficacy of topical basil (Ocimum basilicum) oil in knee osteoarthritis by Alireza Askari, Fatemeh Sadat Hasheminasab, Fatemeh Sadat Hasheminasab, Omid Sadeghpour, Mohammad Mehdi Naghizadehd, Seyed Ali Ravansalar, Aida Iraji, Mohammad Hashem Hashempur

“…This suggests that basil oil could be considered an effective management option for this condition.Clinical Trial Registration:https://irct.behdasht.gov.ir/, identifier IRCT2017081711341N7.…”
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The omission of pumice prophylaxis on bracket failure rates after using self-etch primers: a randomised controlled clinical trial by Thevadass Kaminii, Zakaria Nor Nadia, Othman Siti Adibah

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