The Association between Hypertension and Dementia in the Elderly by Michiya Igase, Katsuhiko Kohara, Tetsuro Miki

“…We found conflicting results regarding treatment benefits in dementia prevention. Recent clinical trials and studies on animal models suggest that blockades of RAS system could have reduced cognitive decline seen in Alzheimer's disease and vascular dementia. …”
Get full text

3D ophthalmic ultrasonography at the slit lamp using existing ultrasound systems. by Jack O Thomas, Josiah K To, Parsa Riazi Esfahani, Frithjof Kruggel, William C Tang, Andrew W Browne

“…Further research and clinical trials are needed to optimize the system's performance and validate its clinical utility.…”
Get full text

Accuracy of the digital implant impression with splinted and non-splinted intraoral scan bodies: A systematic review by Pratiksha Shankar Shetty, Arti P. Gangurde, Manish R. Chauhan, Niraja V. Jaiswal, Pradnya R. Salian, Vikram Singh

“…Inclusion criteria encompassed clinical trials, in vivo and in vitro studies on scan bodies in partially or fully edentulous arches. …”
Get full text

Validated UPLC-MS/MS Method for Determination of Futibatinib and Its Pharmacokinetics in Beagle Dogs by Heng Li, Hao-Zhe Ding, Yi-Lin Wang, Feng Zhang, Ya-Hao Song, Xiang-Jun Qiu

“…Futibatinib, a highly selective, irreversible potent fibroblast growth factor receptor (FGFR) inhibitor, has been proved to be effective in clinical trials of intrahepatic cholangiocarcinoma (ICCA) patients. …”
Get full text

Botox (OnabotulinumtoxinA) for Treatment of Migraine Symptoms: A Systematic Review by Negar Shaterian, Negin Shaterian, Aref Ghanaatpisheh, Farnaz Abbasi, Sara Daniali, Maryam Jalali Jahromi, Mohammad Sadegh Sanie, Amir Abdoli

“…According to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines, we searched online databases, including Web of Science, PubMed, EMBASE, Scopus, Cochrane Library, ProQuest, ClinicalTrials.gov, and Google Scholar from 2011 to 2021. …”
Get full text

Vascular endothelial growth factor A: friend or foe in the pathogenesis of HIV and SARS-CoV-2 infections? by Mieke A. van der Mescht, Helen C. Steel, Ronald Anderson, Theresa M. Rossouw

“…In this context, a few clinical trials have described a diminished requirement for oxygen therapy during anti-VEGF treatment of SARS-CoV-2 infection. …”
Get full text

Multidisciplinary Collaboration and Novel Technological Advances in Hadron Therapy by Manjit Dosanjh PhD, Alberto Degiovanni PhD, Maria Monica Necchi PhD, Elena Benedetto PhD

“…Advances in accelerator-driven Boron Neutron Capture Therapy (BNCT), image-guided hadron beams delivery, clinical trials and immunotherapy, together with the recent interest and advances in FLASH therapy, which is currently an experimental treatment modality that involves ultrahigh-dose rate delivery, are just a few examples of innovation that may eventually help to provide access to a larger number of patients.…”
Get full text

Prevalence and risk factors of under-five mortality due to severe acute malnutrition in Africa: a systematic review and meta-analysis by Joshua Wambua, Anahita Ali, Jean Baptiste Ukwizabigira, Paul Kuodi

Get full text

Practice Variations in the Use of Novel Oral Anticoagulants for Nonvalvular Atrial Fibrillation-Related Stroke among Stroke Neurologists in Saudi Arabia by Mohammed H. Alanazy, Taim Muayqil

“…Clinical trials have demonstrated that novel oral anticoagulants (NOACs) are noninferior to warfarin in preventing nonvalvular atrial fibrillation- (nvAF-) related stroke and systemic embolism. …”
Get full text

NoFumo+: Mobile Health App to Quit Smoking Using Cognitive-Behavioral Therapy by Patricia García-Pazo, Joana Fornés-Vives, Albert Sesé Abad

“…Finally, investigation project registered in ClinicalTrials.gov with reference to this trial is registered with NCT045402004.…”
Get full text

Quality of Life in Wilson’s Disease: A Systematic Literature Review by Chakrapani Balijepalli, Kevin Yan, Lakshmi Gullapalli, Stephane Barakat, Helene Chevrou-Severac, Eric Druyts

“…**Methods:** To address this gap in the literature, we conducted a systematic literature review in MEDLINE and EMBASE to identify observational studies and clinical trials reporting QOL outcomes among people living with WD. …”
Get full text

Comparing robot-assisted and conventional surgery in knee replacement: A meta-analysis of surgical-site wound complications and recovery outcomes by Hu Liang, Yangquan Hao, Wenxing Yu

“…A total of 590 publications were explored, and 16 related randomized clinical trials (RCTs) were analyzed in depth to unveil the role of robots in knee replacement surgery. …”
Get full text

The impact of quantitative platform on candidacy for bronchoscopic lung volume reduction: a multi-center retrospective cohort study by Max Wayne, Suchitra Pilli, Hee Jae Choi, Nathaniel Moulton, Praveen Chenna, Allen Cole Burks, Alexander Chen

“…The recommendation to proceed with BLVR was based on a prespecified algorithm using criteria established in clinical trials for each quantitative platform, respectively. …”
Get full text

COLORATION AND DISCOLORATION OF OLVEOLAR BONE AND TOOTH ENAMEL CAUSED BY MEDICATION by Giurgiu Cristian Levente, George Morarasu, Nicolae Baranov, Pogăcian-Maier Alexandra-Camelia, Radu-Mircea Sireteanu-Cucui, Cristina Pipa, Alina Monica Miftode, Alina Stefanache

“…Keywords related to tooth discoloration and medications were used to identify relevant studies, including clinical trials and case reports published between 1990 and 2023. …”
Get full text

A meta-analysis of the effectiveness and side effects of hip arthroscopy and open surgical dislocation in the management of femoroacetabular impingement by Chenlie Ni, Haiqing Lin, Haibo Yin

“…The purpose of this meta-analysis is to assess the effectiveness and safety of hip arthroscopy compared to open surgical dislocation for the treatment of femoroacetabular impingement (FAI), based on clinical trials that have been published. Methods A comprehensive literature search was conducted through PUBMED, EMBASE, and the Cochrane Central Register of Controlled Trials for studies evaluating coxoscopy and open surgical dislocation as treatment modalities for femoroacetabular impingement syndrome (FAI). …”
Get full text

Rehabilitation and violence-related traumatic brain injury: A scoping review. by Samira Omar, Maria Jennifer Estrella, Muzna Ahmad, Angela Colantonio, Jessica Babineau, Vincy Chan

“…., MEDLINE, Cochrane CENTRAL Register of Clinical Trials, CINAHL, APA PsycINFO, Criminal Justice Abstracts, Applied Social Sciences Index and Abstracts, and Proquest Nursing and Allied Health) and grey literature (i.e., relevant organizations' websites) were systematically searched for peer-reviewed articles and reports that met eligibility criteria. …”
Get full text

An Overview of the Skin Microbiome, the Potential for Pathogen Shift, and Dysbiosis in Common Skin Pathologies by Anita Smith, Roberta Dumbrava, Noor-Ul-Huda Ghori, Rachael Foster, James Campbell, Andrew Duthie, Gerard Hoyne, Marius Rademaker, Asha C. Bowen

Get full text

Management Practice and Clinical Outcomes of Dementia in Sub-Saharan Africa: A Systematic Review by Dessale Abate Beyene, Alemseged Beyene Berha

“…Finally, five randomized clinical trials (RCT) and three prospective cohort studies that were reported on the management practice and treatment outcome of dementia in SSA were eligible for analysis. …”
Get full text

Analgesic effect of intravesical lignocaine in urology surgery: A systematic review and meta-analysis by Ka T. Ng, Wei E. Lim, Wan Y. Teoh, Ahmad N. B. Fadzli, Mohd F. B. Z. Abidin

“…Methods: The MEDLINE, EMBASE, and CENTRAL databases were searched from their start date until December 2024. Randomised clinical trials (RCTs) were included, comparing intravesical lignocaine and control for bladder irrigation in adults undergoing urological surgery. …”
Get full text

Case Reports: The core of practice-based evidence by Antonio Villa

“…The great value of case reports is shown by the fact that they are being increasingly published by scholar journals, in a time where researchers need to publish clinical trials and systematic reviews to get adequate visibility and more impact factor [2]. …”
Get full text