Randomised feasibility study of an intestinal adsorbent in acute diarrhoea in The Gambia by Elena Markaryan, Matthew Dodd, Stephen Allen, Carol Howell, Angela Allen, Paul Rahden, Abdoulie Fatty, Momodou Lamin Jobarteh, Abdoulwahab Sallah, Ebrahim Jaiteh, Doreen Umoh, Fanta Bass, Radovan Hnatič

“…One serious event (death) occurred in the control arm.Conclusions A randomised, controlled trial is feasible. Further clinical trials are warranted to confirm the efficacy of polymethylsiloxane polyhydrate in acute diarrhoea and inform management guidelines.Trial registration number PACTR202302683128875.…”
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Ketogenic diet in psychiatry: application in treating depression among athletes by Paulina Kumięga, Zuzanna Kudas, Nikola Perchel, Aleksandra Litwin, Karolina Krzywicka, Paweł Nowocin, Piotr Wasiński, Natalia Dąbrowska, Martyna Koszyk, Dawid Kulczyński

“…This review synthesizes findings from recent clinical trials, meta-analyses, and case studies focusing on KD's neurological and psychological effects. …”
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Balancing CIK Cell Cancer Immunotherapy and PPAR Ligands: One Potential Therapeutic Application for CNS Malignancies by Kira Vordermark, JingJing Pu, Amit Sharma, Jarek Maciacyzk, Ingo G. H. Schmidt‐Wolf

“…ABSTRACT Background Cytokine‐induced killer (CIK) cell therapy has proven successful in clinical trials regarding glioblastoma. Equally important are the hints suggesting peroxisome proliferator‐activated receptors (PPARs) ligands being co‐expressed in the central nervous system (CNS). …”
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T-Cell Subsets in Rheumatoid Arthritis Patients on Long-Term Anti-TNF or IL-6 Receptor Blocker Therapy by Sonja Dulic, Zsófia Vásárhelyi, Florentina Sava, László Berta, Balázs Szalay, Gergely Toldi, László Kovács, Attila Balog

“…This study provides comprehensive information regarding the long-term impacts of those biological therapies on the ecotaxis of T-cells in RA. The ClinicalTrials.gov registration number of our study is NCT03266822.…”
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Chemical Identification and Antioxidant Screening of Bufei Yishen Formula using an Offline DPPH Ultrahigh-Performance Liquid Chromatography Q-Extractive Orbitrap MS/MS by Jinyan Wu, Bangrong Cai, Ang Zhang, Peng Zhao, Yan Du, Xuefang Liu, Di Zhao, Liu Yang, Xinguang Liu, Jiansheng Li

“…Chronic obstructive pulmonary disease (COPD) has high morbidity and mortality and presents a threat to human health worldwide. Numerous clinical trials have confirmed that Bufei Yishen formula (BYF), an herbal medicine, can alleviate the symptoms of COPD by reducing oxidative stress-mediated inflammation. …”
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Comparative Effects of Glenzocimab and Eptifibatide on Bleeding Severity in 2 Mouse Models of Intracranial Hemorrhage by Sébastien Dupont, Héloïse Lebas, Sabrina Mavouna, Eloïse Pascal, Astride Perrot, Adrien Cogo, Marie‐Charlotte Bourrienne, Carine Farkh, Mialitiana Solo Nomenjanahary, Véronique Ollivier, Fatima Zemali, Bernhard Nieswandt, Stéphane Loyau, Martine Jandrot‐Perrus, Eric Camerer, Jean‐Philippe Desilles, Mikael Mazighi, Yacine Boulaftali, Benoît Ho‐Tin‐Noé

“…Here, we investigated this risk for 2 antiplatelet drugs currently being tested in clinical trials for ischemic stroke, glenzocimab and eptifibatide, in 2 mouse models of ICH. …”
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Efficacy of Once Daily versus Divided Daily Administration of Low Daily Dosage (15 mg/Day) of Methimazole in the Induction of Euthyroidism in Graves’ Hyperthyroidism: A Randomized... by Sutin Sriussadaporn, Wanwaroon Pumchumpol, Raweewan Lertwattanarak, Tada Kunavisarut

“…This trial is registered with Thai Clinical Trials Registry: TCTR20170529001.…”
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Towards a Rational Design of an Asymptomatic Clinical Herpes Vaccine: The Old, the New, and the Unknown by Aziz Alami Chentoufi, Elizabeth Kritzer, David M. Yu, Anthony B. Nesburn, Lbachir BenMohamed

“…However, in spite of several clinical trials, starting as early as 1920s, no vaccine has been proven sufficiently safe and efficient to warrant commercial development. …”
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Fecal Microbiota Transplantation: A Systematic Review of Therapeutic Potential, Preparation Techniques, and Delivery Methods Across Medical Conditions by Syamand Ahmed Qadir, Qausar Hamed ALKaisy, Abdulbasit F. Hasan, Farhang Hameed Awlqadr, Ammar B. Altemimi, Aryan Mahmood Faraj, Angelo Maria Giuffrè, Mohammed N. Saeed, Sherzad Rasul Abdalla

“…A comprehensive search of PubMed, Web of Science, Scopus, Embase, and ClinicalTrials.gov from January 2000 to December 2023 identified 97 relevant studies on FMT's efficacy, safety, and microbiome changes after eliminating duplicates. …”
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Discovery of a non‐nucleotide stimulator of interferon genes (STING) agonist with systemic antitumor effect by Xiyuan Wang, Zhengsheng Zhan, Zhen Wang, Yan Zhang, Kaiyan Zhao, Han Li, Xiaoqian Zhou, Yuting Guo, Fengying Fan, Jian Ding, Meiyu Geng, Xuekui Yu, Wenhu Duan, Zuoquan Xie

“…Although progress in clinical trials for STING agonists in antitumor applications has been slow, there is still an urgent need for developing new potent STING agonists with versatile potential applications. …”
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Stemness Maintenance Properties in Human Oral Stem Cells after Long-Term Passage by Francesca Diomede, Thangavelu Soundara Rajan, Valentina Gatta, Marco D’Aurora, Ilaria Merciaro, Marco Marchisio, Aurelio Muttini, Sergio Caputi, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani

“…Our results suggest that the presence of embryonic and proliferation markers even in late passage may potentially endorse the application of dental-derived MSCs in stem cell therapy-based clinical trials.…”
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PRESBYACOUSSIS: JUSTIFICATION OF DIAGNOSIS IN SCREENING CONDITIONS by K.E. Gubskaya, M.M. Baibulov, Dinara Urazalina, Gulnara Tuleshova

“…After selection and analysis, the results of 6 studies were taken into work, including 3 randomized clinical trials and 3 observational studies. Taking into account global trends, an analysis of the validity of the search for effective methods for diagnosing presbycusis was carried out. …”
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Assessing the effectiveness of the SOLIO Alfa Cure Plus device in treating low back pain: a randomized controlled study by Hadari Yotam, Pesah Galia, Goor-Aryeh Itay, Ungar Lior

“…Trial registration: The clinical trials registration is 8475-21-SMC.…”
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Comparison of the risk of obesity in the FTO rs9939609 genotype in a multiethnic group in Asia systematic review and meta-analysis by Donna Pratiwi, Miko Sidartha, Elvan Wiyarta, Elvan Wiyarta, I Wayan Agustinus Harimawan, Ni Made Dwi Asti Lestari, Bonglee Kim, Nurpudji Astuti Taslim, Trina Ekawati Tallei, Fahrul Nurkolis, Rony Abdi Syahputra

“…AimThis study aims to examine the comparative risk of obesity in the FTO rs9939609 genotype in multiethnic groups in Asia, considering that obesity has become a global disease.Data synthesisData searches were carried out in several electronic databases: PubMed, Scopus, Google Scholar, ScienceDirect, ClinicalTrials.gov and NCBI. The search involved a combination of keywords related to genetics and obesity risk. …”
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Enhancing foster care relationships through attachment-based intervention: the safe families study protocol, a randomized controlled trial of the circle of security parenting progr... by Mathieu Pereira, Lauriane Sedes, Emilie Gadéa, Rebecca Shankland

“…Trial registration This trial is registered on ClinicalTrials.gov : NCT06701877.…”
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Unlocking prognostic potential: A genomic signature of caloric restriction in patients with epithelial ovarian cancer. by Ori Tal, Tamar Zahavi, Liat Anabel Sinberger, Mali Salmon-Divon

“…Further investigations, including clinical trials, are warranted to validate these findings and explore the broader applicability of non-fasting genomic signatures in other cancer types.…”
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Prevalence of Albuminuria in Cardiology and Endocrinology Departments and Its Influencing Factors: A Multicenter, Real-World Evidence Study in China by Qian Ren, Changsheng Ma, Jiguang Wang, Xiaohui Guo, Linong Ji

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Potentiating intratumoral therapy with immune checkpoint inhibitors: shifting the paradigm of multimodality therapeutics by B.E. Nelson, A. Naing, S. Fu, R.A. Sheth, R. Murthy, S. Piha-Paul

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Effects of Oral Inflammatory Diseases and Oral Hygiene on Atrial Fibrillation: A Systematic Review by Zhanxin Zhang, Fei Chen, Xueying Gao, Bing Xiao, Fan Liu, Jingchao Lu

“…The primary outcomes were the risk of new-onset atrial fibrillation in patients with oral disease, the effect of regular oral care on preventing atrial fibrillation, the effect of frequent tooth brushing on preventing atrial fibrillation, and the incidence of atrial fibrillation in PD patients. Results. Eight clinical trials with a total of 4,328,355 patients were included. …”
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PReventing Idiopathic SCOliosis PROgression (PRISCOPRO): A protocol for a quadruple-blinded, randomized controlled trial comparing 3D designed Boston brace to standard Boston brace... by Elias Diarbakerli, Anastasios Charalampidis, Allan Abbott, Paul Gerdhem

“…<h4>Trial registration</h4>The protocol has been registered on ClinicalTrials.gov, identifier: NCT04805437.…”
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