Implementing injury prevention training in youth handball (I-PROTECT) in Sweden: study protocol for a cluster randomised trial by Per Nilsen, Alex Donaldson, Eva Ageberg, Sofia Bunke, Jennie Linnéll, Karin Moesch, Karolina Lucander, Axel Ström, Robert Wedberg, Per Ekberg

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A high fraction of inspired oxygen does not mitigate atelectasis-induced lung tissue hypoxia or injury in experimental acute respiratory distress syndrome by Kentaro Tojo, Takuya Yazawa

“…Abstract Although alveolar hyperoxia exacerbates lung injury, clinical studies have failed to demonstrate the beneficial effects of lowering the fraction of inspired oxygen (FIO2) in patients with acute respiratory distress syndrome (ARDS). …”
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Prevalence, Etiology, and Risk Factors of Mastitis in Dairy Cattle in Embu and Kajiado Counties, Kenya by Christine M. Mbindyo, George C. Gitao, Charles M. Mulei

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Diabetic Peripheral Neuropathy Affects Pinch Strength and Hand Dexterity in Elderly Patients by Qi Zhang, Yifang Lin, Xinhua Liu, Li Zhang, Yan Zhang, Dong Zhao, Qi Lu, Jie Jia

“…In past research and clinical studies, the lower limb function of DPN patients was often the principal subject of research, with little attention given to the upper limb and hand. …”
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Balloon dilation for the treatment of male urethral strictures: a systematic review and meta-analysis by Tianyu Cai, Xiaoyu Li, Jian Lin, Chunru Xu, Xing Ji, Zhenpeng Zhu, Zhenke Guo

“…The aim of this study was to review and discuss the safety, efficacy and factors influencing the clinical application of balloon dilation for the treatment of male urethral strictures.Design Systematic review and meta-analysis.Data sources Embase, Medline, Web of Science, Cochrane Library and Scopus were searched for publications published before 17 July 2022.Study selection Two independent researchers screened and assessed the results, and all clinical studies on balloon dilation for the treatment of urethral strictures in men were included.Data extraction and synthesis The success rate, rate of adverse events, International Prostate Symptom Scores, maximum uroflow (Qmax) and postvoid residual urine volume were the main outcomes. …”
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Metformin as an adjuvant option for systemic treatment of breast cancer by D.I. Avierin, V.F. Zavizion

“…On this subject only four clinical studies were carried out, and only one of them pertained to the implementation of metformin in the systemic treatment of breast cancer. …”
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Progress in Study of Low-Intensity Pulsed Ultrasound Acting on Inflammation-Related Signaling Pathways in Knee Osteoarthritis by OUYANG Hui, LIN Xingjin, WANG Jinying, SHEN Longbin, WANG Chengdong

“…This article provides a theoretical basis for clinical studies and combination treatment options for LIPUS by reviewing the research progress on the role of LIPUS in KOA inflammation-related signaling pathways.…”
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Cohort profile: Outcome Monitoring After Cardiac Surgery (OMACS) – a prospective UK cohort study of cardiac surgery patients at the Bristol Heart Institute by Chris A Rogers, Gianni Angelini, Lucy Culliford, Rachel Brierley, Barnaby Reeves, Katherine Joyce, Terrie Walker-Smith, Rachel Maishman, Emma Hopkins, Penny Lambert, Helena Smartt

“…The objectives were to use these data to inform the design of new clinical studies and to provide samples and data to answer research questions.Participants Recruitment began on 23 May 2016 and ended 31 May 2022. …”
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CircBAZ1B stimulates myocardial ischemia/reperfusion injury (MI/RI) by modulating miR-1252-5p/ATF3-mediated ferroptosis by Ruili Wei, Tianxiao Yang, Weihong Li, Xiqian Wang

“…Inhibiting this pathway may alleviate MI/RI effects, suggesting the need for further clinical studies.…”
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Meta-analysis of nifedipine and enalapril combination therapy for hypertensive patients with coronary heart disease: A systematic review and meta-analysis by Kun Wang, Wenchao Ma, Leina Sun, Fangcheng Su

“…Background: Numerous clinical studies have demonstrated that the therapeutic efficacy of combining nifedipine and enalapril in treating hypertension with coronary heart disease surpasses that of nifedipine as a stand-alone treatment. …”
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Physical, chemical and biological properties of MTA Angelus and novel AGM MTA: an in vitro analysis by Sara Nashibi, Parisa Amdjadi, SeyedehSana Ahmadi, Sara Hekmatian, Maryam Torshabi

“…However, further clinical studies are required to confirm its application.…”
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Elucidating the knowledge, attitude, and stigma associated with tuberculosis: a community based descriptive study in Wau and Jur River, South Sudan by Peter Michael Marin, Morten Tryland, Musso Munyeme, Ambrose Samuel Jubara, Enock Matovu, Peter Waiswa, Javier Sanchez Romano, Francis Mutebi, David Onafruo, Estella Kitale, Esther Sabbath, Kayla J. Buhler, Clovice Kankya

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Toxicity and Safety Evaluation of Doxorubicin-Loaded Cockleshell-Derived Calcium Carbonate Nanoparticle in Dogs by Abubakar Danmaigoro, Gayathri Thevi Selvarajah, Mohd Hezmee Mohd Noor, Rozi Mahmud, Md Zuki Abu Bakar

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Comparison of the safety of remimazolam and propofol during general anesthesia in elderly patients: systematic review and meta-analysis by Xianchun Liu, Longyi Zhang, Li Zhao, Xuelei Zhou, Wei Mao, Linlin Chen, Hongyu Zhu, Ying Xie, Linji Li

“…For elderly patients with declining physical and physiological function, anesthesia safety is crucial. Most current clinical studies compare the safety of remimazolam and propofol, though the results are inconsistent. …”
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Intracellular iron accumulation throughout the progression of sepsis influences the phenotype and function of activated macrophages in renal tissue damage by Mira Hanna, Ahmed M. A. Akabawy, Mohamed Mansour Khalifa, Mohamed Mansour Khalifa, Marawan Abd Elbaset, Reda Abdelnasser Imam, Hanan Seddiek

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Extracorporeal Shockwave Therapy Reduces Pain and Improves Internal Rotation after Arthroscopic Capsular Release: A Randomized Clinical Trial by Zifan Lin, Hong Shao, Jun Chen, Wei Yao, Chang Liu, Zhengbiao Jin, Yunxia Li

“…There is still no consensus on the treatment of frozen shoulder (FS). Clinical studies on extracorporeal shockwave therapy (ESWT) combined with arthroscopic capsular release (ACR) for FS are still lacking. …”
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Real-world clinical experience with secukinumab in psoriatic arthritis: an observational study and a literature review by Eleonora Celletti, Giulio Gualdi, Emanuela Sabatini, Francesco Cipollone, Fabio Lobefaro, Paolo Amerio

“…Psoriatic arthritis (PsA) can be treated with biological drugs targeting IL-17A, such as secukinumab, with good responses and long-term positive outcomes in clinical studies. Methods. An observational study was conducted on adult subjects with PsA and comorbidities, treated with secukinumab after prior therapy with conventional disease-modifying anti-rheumatic drugs or biological agents that were discontinued due to lack of efficacy or adverse drug reactions. …”
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Phage therapy in the management of respiratory and pulmonary infections: a systematic review by Patience Sarkodie-Addo, Abdul-Halim Osman, Bill Clinton Aglomasa, Eric S. Donkor

“…Consequently, there is a need for additional clinical studies to establish standardised pharmacokinetic elements and an overall protocol for PT. …”
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Outcomes of different surgical procedures for optic disc pit: a meta-analysis by Hussain A. Khaqan, Raheela Naz, Hafiz A. ur Rehman, Laraib Hassan, Nabeel Akram, Hafiz M. Farooqui, Ahmad Fauzan, Asad M. Khan

“…Methods We conducted a literature search to identify clinical studies and case series of surgically treated OPM patients. (1) greater than two patients, (2) surgical treatment and (3) reporting of pre and postoperative visual acuity data were inclusion criteria. …”
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UPLC-MS/MS Method for Givinostat in Rat Plasma: Development, Validation, in vivo Pharmacokinetics Study and in vitro Metabolic Stability Research by Zhan R, Liu Y, Wu J, Shen Y, Xu X, Lin G, Chen X

“…This study provides a potential reference for givinostat in clinical studies.Keywords: givinostat, UPLC-MS/MS, rat plasma, pharmacokinetic study, in vitro metabolic stability…”
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