Potential therapeutic effects of apigenin for colorectal adenocarcinoma: A systematic review and meta‐analysis by Koohyar Ahmadzadeh, Shayan Roshdi Dizaji, Fatemeh Ramezani, Farnad Imani, Jebreil Shamseddin, Arash Sarveazad, Mahmoud Yousefifard

“…However, further in vivo studies are needed before any efforts to translate the current evidence into clinical studies.…”
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Not All SLAPs Are Created Equal: A Comparison of Patients with Planned and Incidental SLAP Repair Procedures by Mark C. Dougherty, J. Erik Kulenkamp, Haroutioun Boyajian, Jason L. Koh, Michael J. Lee, Lewis L. Shi

“…We hypothesized that both isolated SLAP repair and secondary SLAP repair increased with time and that patient age influenced the pathway to SLAP diagnosis and surgery—such that younger patients were more likely to have isolated SLAP repair surgery after being diagnosed in clinic. Study Design. Descriptive epidemiology study. …”
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A real-world pharmacovigilance analysis of potential ototoxicity associated with sacubitril/valsartan based on FDA Adverse Event Reporting System (FAERS) by Ning Wang, Haijun Wang, Ying Chen, Yanfeng Wang

“…Sacubitril/valsartan-associated ototoxicity is often underreported in clinical studies and real-world settings. This study aimed to systematically characterize ototoxicity profiles using post-marketing data. …”
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Robotic Systems for Hand Rehabilitation—Past, Present and Future by Bogdan Gherman, Ionut Zima, Calin Vaida, Paul Tucan, Adrian Pisla, Iosif Birlescu, Jose Machado, Doina Pisla

“…<b>Conclusions:</b> While substantial progress has been made in recent years, several challenges persist, including missing information or incomplete data from source papers and a limited number of clinical studies to evaluate device effectiveness. Significant opportunities remain to improve device functionality, usability, and therapeutic effectiveness, as well as to implement advanced power systems for portable devices.…”
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Using ICT Tools for Exploring the Impact of Urban Blue-Green Spaces on Human Health and Well-Being by Sanja IVANKOVIC, Dragana JOVANOVIC, Predrag SAVIC, Vesna KARADŽIĆ, Milena VASIĆ

“…The primary methodological approach of HEART clinical studies across three demonstration cities focuses on understanding how HEART project interventions relate to four chronic disease groups: cardiovascular, respiratory, mental, and metabolic conditions, with healthy participants as the control group. …”
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Harnessing the anticancer potential of Piper nigrum: a synergistic approach to chemotherapy enhancement and reduced side effects by Hesti Lina Wiraswati, Ilma Fauziah Ma’ruf, Nur Akmalia Hidayati, Julia Ramadhanti, Daniela Calina, Javad Sharifi-Rad

“…The review evaluates the recent findings from in vitro, in vivo, and clinical studies, emphasizing PNE's capacity to enhance the efficacy of conventional chemotherapeutic agents while mitigating their side effects. …”
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Effects of Dietary Strawberry Supplementation on Antioxidant Biomarkers in Obese Adults with Above Optimal Serum Lipids by Arpita Basu, Stacy Morris, Angel Nguyen, Nancy M. Betts, Dongxu Fu, Timothy J. Lyons

“…Berries have shown several cardiovascular health benefits and have been associated with antioxidant functions in experimental models. Clinical studies are limited. We examined the antioxidant effects of freeze-dried strawberries (FDS) in adults [n=60; age: 49±10 years; BMI: 36±5 kg/m2 (mean ± SD)] with abdominal adiposity and elevated serum lipids. …”
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Genistein Implications in Radiotherapy: Kill Two Birds with One Stone by Xiongxiong Liu, Tong Zheng, Yanyu Bao, Ping Li, Ting Zhao, Yan Liu, Hui Wang, Chao Sun

“…Despite limited clinical studies, the existing evidence supports the potential of genistein in improving the therapeutic effect of radiotherapy. …”
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Scanning Electron Microscopic Assessment of Stent Coating Integrity in Jailed Wire Technique for Bifurcation Treatment by Lijian Gao, Ce Zhang, Huanhuan Wang, Yiqun Zhang, Zhan Gao, Bo Xu, Jue Chen, Jinqing Yuan, Shubin Qiao, Jilin Chen

“…Although nonpolymer-jacketed wire has long been recommended for JWT, our bench-side study suggests that full polymer-jacketed wire may be a better choice. Further clinical studies are needed to confirm our findings.…”
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Impact of metformin on disease control and survival in patients with head and neck cancer: a retrospective cohort study by Daniel J. Lee, Caitlin P. McMullen, Andrew Foreman, Shao Hui Huang, Lin Lu, Wei Xu, John R. de Almeida, Geoffrey Liu, Scott V. Bratman, David P. Goldstein

“…Abstract Objective A number of in vitro and clinical studies have suggested potential antineoplastic effects of metformin. …”
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Assessment of relationships between epigenetic age acceleration and multiple sclerosis: a bidirectional mendelian randomization study by Hongwei Liu, Hanqing Zhang, Zhaoxu Yin, Miaomiao Hou

“…Conclusions Our Mendelian randomization analysis revealed that epigenetic age acceleration of HannumAge was causally associated with multiple sclerosis, and provided novel insights for further mechanistic and clinical studies of epigenetic age acceleration-mediated multiple sclerosis.…”
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Does quercetin affect tendon healing? An experimental study in a rat model of Achilles tendon injury by Ahmet Yurteri, Numan Mercan, Zeliha Esin Çelik, Hakan Yaykaşlı, Ahmet Yıldırım

“…However, further clinical studies are needed to understand its effects on human tendon healing, as this is the first study of its kind.…”
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Prosaposin – A plausible biomarker in head and neck squamous cell carcinoma by Avradeep Datta, Rajandeep Kaur, Anshika Chauhan, Geeta Singh Boora, Himanshu Garg, Debajyoti Chatterjee, Jaimanti Bakshi, Sushmita Ghoshal, Arnab Pal

“…Further large-scale clinical studies are warranted to establish serum PSAP as a diagnostic/prognostic marker in HNSCC patients.…”
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<i>Ajuga reptans</i> L. Herb Extracts: Phytochemical Composition and Pharmacological Activity Screening by Svitlana Maliuvanchuk, Andriy Grytsyk, Oksana Popadynets, Taras Kotyk, Ain Raal, Oleh Koshovyi

“…<i>A. reptans</i> herb extracts are promising agents for implementation in official medicine as wound healing and hepatoprotective remedies after further preclinical and clinical studies.…”
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Dental implant placement accuracy with robotic surgery compared to free-hand, static and dynamic computer assisted techniques: Systematic review and meta-analysis by Hariram Sankar, M. Shalini, Anjana Rajagopalan, Satish Gupta, Amit Kumar, Rukhsar Shouket

“…However, this finding should be interpreted with caution due to the limited number of clinical studies and potential funding biases. Moreover, the high cost of robotic systems presents challenges for routine clinical implementation. …”
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Comparative efficacy of topical commercial Chinese polyherbal preparation for vulvovaginal candidiasis: a network meta-analysis by Lizheng Wu, Shangwen Jing, Na Li, Dandan Cao, Fangli Pei, Yantong Luo, Xiaoxin Chen, Yingjie Huang, Cheng Zeng

“…However, due to the low quality of the included literature, larger-scale, higher-quality clinical studies are still needed.Systematic Review RegistrationPROSPERO, NO: CRD42023410244.…”
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Tire rubber-derived contaminants 6PPD and 6PPD-quinone reduce attachment and outgrowth of trophoblast spheroids onto endometrial epithelial cells by Jong Geol Lee, Seon Min Lee, Moonjung Hyun, Jeong Doo Heo

“…The study provides the first proof of the adverse effects of 6PPD and 6PPDQ on human endometrial receptivity and trophoblast invasion during the window of implantation, warranting the need for further in vivo and clinical studies.…”
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Accuracy and operation procedure of robotic computer-aided implant surgery by Yitian Liu, Qingqing Zheng, Zonghe Xu, Yanjun Lin, Sihui Zhang, Wenxiu Huang, Jiang Chen, Dong Wu

“…However, there remains a need to optimize robotic systems to simplify the workflow and improve their ability to recognize and respond to complex bone structures. Further clinical studies should also focus on comparing the long-term implant success rate and related complications of rCAIS with traditional approaches.…”
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Investigations of Long-Acting Formulations in Children, Adolescents, and Pregnant Women: A Systematic Review by Lynn Bertagnolli, Zhengyi Deng, Melissa Davy-Rothwell, Elaine J. Abrams, Charles Flexner, Ethel D. Weld

“…We conducted a systematic review of all clinical studies involving the use of a long-acting intramuscular injection or implant in infants, children, young people, and pregnant and postpartum people. …”
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Anti-allergic potentials of Ceriops decandra leaves in TDI-induced allergic mice: Comprehensive in-vivo and in-silico studies by Aishwarja Dey, Subarna Rani, Rabindra Nath Acharyya, Apurba Kumar Barman, Khondoker Shahin Ahmed, Nripendra Nath Biswas, Shrabanti Dev, Asish Kumar Das

“…Conclusion: C. decandra is safe and rich in several polyphenolic compounds which are effective against allergic syndromes which could be an effective option for the management of allergic symptoms, although clinical studies are required to establish the herbal formulation.…”
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