Integral Roles of Specific Proteoglycans in Hair Growth and Hair Loss: Mechanisms behind the Bioactivity of Proteoglycan Replacement Therapy with Nourkrin® with Marilex® in Pattern... by Jan Wadstein, Erling Thom, Aida Gadzhigoroeva

“…To address FHG and PFA, a proteoglycan replacement therapy (PRT) program using oral administration of a marine-derived extract (Nourkrin® with Marilex®, produced by Pharma Medico Aps, Aarhus, Denmark) containing specific proteoglycans has been developed. In clinical studies, this treatment significantly reduced hair fall, promoted hair growth, and improved quality of life in patients with male- and female-pattern hair loss. …”
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Update on Low-Molecular Weight Hyaluronic Acid in Dermatology: A Scoping Review by Stephanie Waggett, Elliott Lyles, Todd Schlesinger

“…However, both pre-clinical and clinical studies have shown numerous applications of HA, low-molecular-weight (LMW) HA, and hybrid LMW/high-molecular-weight HA in dermatology. …”
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Dry eye syndrome, associated with the wearing of contact lenses. Features of the therapeutic approach by E.A. Egorov

“…<br> The data of clinical studies confirming the effectiveness of the inclusion of innovative eye drops, based on cationic emulsion,&nbsp;<br> in the treatment regimen of DES are presented. …”
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Evaluation of the Value of Fine Needle Aspiration Cytology and Cell Morphology in Determining the Histogenesis of Pancreatic Lesions With Review of Literature, Overview and Cytolog... by Soudah Bisharah, Abbas Mahmoud

“…In general, it is routine in the university that the patients give their written consent to participate in clinical studies. The local ethics committee has stated that there is no need for approval due to the retrospective nature of the study. …”
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Exploring a New Cueing Device in People Who Experience Freezing of Gait: Acceptance of a Study Design by Agnes Wilhelm, Tanja Riedl, Christian Paumann, Jessie Janssen

“…Feedback from open ended questions provided ideas and considerations for adaptations of future clinical studies. Conclusion. The proposed study design was acceptable for people with PD. …”
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Alterations of Some Apolipoprotein Levels and ApoE RNA Expression in Iraqi Patients with Chronic Hepatitis B Viral Infection by Amnah Raad Ibrahim, Raghad Hassan Hussein, Athraa Zaidan Hassan

“…Background: The high prevalence of hepatitis B virus (HBV) makes it a significant health concern, especially in Iraq. Clinical studies have found that chronic HBV infection affects the occurrence of cardiovascular disease (CVD) by regulating cholesterol metabolism in liver cells. …”
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A Systematic Review of Spironolactone Nano-Formulations for Topical Treatment of Skin Hyperandrogenic Disorders and Chronic Wounds by Saedah Dereiah, Muhammad Usman Ghori, Barbara R. Conway

“…However, further clinical studies are required to optimize their safety, efficacy, and delivery mechanisms.…”
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Relevance of anaesthesia type on early neurological outcome in acute ischemic stroke patients undergoing mechanical thrombectomy by L. Šalaševičius, A. Vilionskis

“…Retrospective studies suggest that GA is associated with worse clinical outcomes, while latest clinical studies show no such difference. Materials and methods. …”
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Modern possibilities of sodium hyaluronate in tear substitutive therapy of patients with “dry eye” syndrome by V.V. Brzheskiy, V.Yu. Popov

“…The results of the experiments were further confirmed by clinical studies in the treatment of patients with DES of various origins. …”
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Risk Factors and Prevention of Upper Gastrointestinal Complications Associated with Nonsteroidal Anti-Inflammatory Drugs by N. V. Bakulina, S. V. Tikhonov, K. A. Nagornova

“…Esomeprazole has a number of pharmacokinetic advantages — a large area under the pharmacokinetic curve, the ability to inhibit CYP4502C19, which determines the high efficiency of therapy in fast and ultrafast metabolizers. Previous clinical studies of esomeprazole for the prevention of NSAID-associated lesions of the upper gastrointestinal tract demonstrate high efficacy. …”
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Clinical and dermoscopic assessment of the efficacy of topical trichloroacetic acid 70% versus methoxsalen 0.2% paint in stable acral vitiligo by Ahmed R. Elshahed, Amr M. Ammar, Abdallah M. Ali, Mohamed L. Elsaie

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Understanding patient views and experiences of the IDENTIfication of PALLiative care needs (IDENTI-Pall): a qualitative interview study protocol by Sarah Mitchell, Isabel Leach, Nicola Turner, C R Mayland

“…Other activities include the development of patient-centred outcomes for clinical practice and policy in relation to the use of palliative care identification tools.Trial registration number National Institute for Health Research (NIHR) Clinical Studies Portfolio, UK Clinical Research Network (UKCRN) Study number 51296.…”
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From Molecule to Patient Rehabilitation: The Impact of Transcranial Direct Current Stimulation and Magnetic Stimulation on Stroke—A Narrative Review by Anca Badoiu, Smaranda Ioana Mitran, Bogdan Catalin, Tudor Adrian Balseanu, Aurel Popa-Wagner, Florin Liviu Gherghina, Carmen Valeria Albu, Raluca Elena Sandu

“…The favorable effects have been demonstrated at the cellular level in animal models and are supported by clinical studies. Thus, these methods proved to reduce infarct volumes and to improve motor performance, deglutition, functional independence, and high-order cerebral functions (i.e., aphasia and heminegligence). …”
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Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment. by Artem Berezovsky, Oluwademilade Nuga, Indrani Datta, Kimberly Bergman, Thais Sabedot, Katherine Gurdziel, Susan Irtenkauf, Laura Hasselbach, Yuling Meng, Claudius Mueller, Emanuel F Petricoin, Stephen Brown, Neeraja Purandare, Sidhesh Aras, Tom Mikkelsen, Laila Poisson, Houtan Noushmehr, Douglas Ruden, Ana C deCarvalho

“…Our integrative analysis of the impact of GBM cell developmental states, in the context of genomic and molecular diversity of patient-derived models, provides valuable insights for pre-clinical studies aimed at optimizing treatment strategies.…”
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GPs’ perspectives on care models integrating medical and non-medical services in primary care—a representative survey in Germany by Wolfram J. Herrmann, Hendrik Napierala

“…Trial registration German Register of Clinical Studies (DRKS-ID: DRKS00032585; Registration Date: September 1, 2023).…”
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The Use of Yoga in the Treatment of PCOS by Agnieszka Przesor Przezor, Natalia Medźwiedzka

“…Conclusions: The literature review and the presented results of clinical studies show that a holistic approach to PCOS treatment, including physical exercise in the form of yoga exercises, has a positive effect on the quality of life of patients. …”
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Modified rice bran arabinoxylan as a nutraceutical in health and disease-A scoping review with bibliometric analysis. by Soo Liang Ooi, Peter S Micalos, Sok Cheon Pak

“…Research progressed with linear growth (median = 3/year) from 1998 to 2022, predominantly on Biobran MGN-3 (86.73%) and contributed by 289 authors from 100 institutions across 18 countries. Clinical studies constitute 61.1% of recent articles (2018 to 2022). …”
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Integrated Mendelian randomization and single-cell RNA-sequencing analyses identified OAS1 as a novel therapeutic target for erectile dysfunction via targeting fibroblasts by Yi Wang, Guihua Chen, Deng Li

“…While these findings highlighted the potential of OAS1 as a therapeutic target, further experimental and clinical studies were still required to validate its functional role and therapeutic relevance in ED pathology.…”
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Dissociative psychosis or dissociative schizophrenia? Comparison of two phenomena by Mahir Akbudak, Hasan Belli, Hasan Gökçay, Uğur Takım

“…Abstract Background In recent years, researchers have reported crucial advances in the understanding of “Dissociative psychosis” and “Dissociative schizophrenia”. While clinical studies in this area have been sustained for well, it remains to be established for some aspects that a clear and valid relationship exists between dissociation, childhood traumatic experiences, and schizophrenia or psychotic spectrum disorders. …”
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Aquatic cycling-What do we know? A scoping review on head-out aquatic cycling. by Stefanie Rewald, Ilse Mesters, Antoine F Lenssen, Jens Bansi, Johan Lambeck, Rob A de Bie, Benjamin Waller

“…Moreover, this comprehensive outline of available literature could serve as a starting point for systematic reviews or clinical studies on the effects of aquatic cycling on the cardiovascular responses.…”
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