Triglycerides mediate the relationships of per- and poly-fluoroalkyl substance (PFAS) exposure with nonalcoholic fatty liver disease (NAFLD) risk in US participants by Wenying Qiao, Jiashuo Li, Lijia Luo, Wenjuan Peng, Xi Wang, Ronghua Jin, Junnan Li

“…Nonalcoholic fatty liver disease (NAFLD) is recognized as a significant public health problem worldwide. Several clinical studies have investigated the associations between Per- and poly-fluoroalkyl substances (PFAS) compounds with the risk of NAFLD in general adults, but the mediating effect of triglycerides (TG) was remained unexplored. …”
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EFFICACY OF AMNIOTIC MEMBRANE MESENCHYMAL STEM CELL THERAPY FOR BURN WOUNDS: META-ANALYSIS STUDY by Bayu Fasi Bermani, Agus Santoso Budi, Magda Rosalina Hutagalung

“…There is, therefore, justification for continued efforts to evaluate variations in future clinical studies using stem cells to treat a burn wound in order to maximize the effectiveness. the use of stem cells as an adjunct to first- line therapies in burns.…”
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A Novel Method (CiMON) for Continuous Intra-Abdominal Pressure Monitoring: Pilot Test in a Pig Model by Joost Wauters, Liesbeth Spincemaille, Anne-Sophie Dieudonne, Kenny Van Zwam, Alexander Wilmer, Manu L. N. G. Malbrain

“…Simplicity, continuous monitoring, and the combination with a feeding tube should lead to further clinical studies, evaluating this new CiMON device.…”
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Vitamin D Deficiency Is Not Associated with Diabetic Retinopathy or Maculopathy by Uazman Alam, Yasar Amjad, Anges Wan Shan Chan, Omar Asghar, Ioannis N. Petropoulos, Rayaz A. Malik

“…Experimental and clinical studies suggest a possible association between vitamin D deficiency and both diabetic retinopathy and maculopathy. …”
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Characteristics of Parthenogenetic Stem Cells and Their Potential Treatment Strategy for Central Nervous System Diseases by Cai H, Huang J, Wang W, Lin W, Ahmed W, Lu D, Quan J, Chen L

“…The origins and characteristics of human parthenogenetic stem cells might lead to a new research area in treating nervous system diseases. The current clinical studies in the field of traumatic brain injury and neurodegenerative diseases are reviewed. …”
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Restoring Teeth with an Advanced Lithium Disilicate Ceramic: A Case Report and 1-Year Follow-Up by Felicitas Hölken, Helmut Dietrich

“…Although more evidence from long-term clinical studies is needed to verify the clinical performance and manufacturer recommendations regarding indication, preparation and cementation must be followed very strictly. …”
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Advances in Illuminating Prostate Cancer with Emerging Phototherapies by Ali Usman

“…Preclinical and clinical studies underline the potential of these multimodal approaches to enhance treatment outcomes, particularly for advanced and castration-resistant prostate cancer. …”
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A modern approach to the treatment of acute low back pain: a proposal of a new treatment algorithm by Robert Rupiński, Urszula Grata-Borkowska, Jarosław Drobnik

“…Considering the clinical studies on low-intensity heat in acute lower back pain, a reduction of at least 25% in NSAID dosage can be expected. …”
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Gut Microbiota–Tumor Microenvironment Interactions: Mechanisms and Clinical Implications for Immune Checkpoint Inhibitor Efficacy in Cancer by Said SS, Ibrahim WN

“…By integrating insights from recent preclinical and clinical studies, we aim to shed light on the potential of microbiome modulation as an adjunct to cancer immunotherapy and as a diagnostic tool, paving the way for personalized therapeutic approaches that optimize patient outcomes.Keywords: ICIs, immunotherapy, gut microbiota, microbiome, tumor microenvironment…”
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Relationship between Mild Genu Varum and Genu Valgum with Degenerative Hip and Knee Disease: A Cadaveric Study by Raymond W. Liu, Douglas S. Weinberg, Jonathan J. Streit, Colin E. Lasko, Daniel R. Cooperman

“…Background: Varus and valgus deformity of the knee are relatively common conditions, and clinical studies have associated both with increased knee arthritis in high-risk patients. …”
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MicroRNAs in atrial fibrillation – have we discovered the Holy Grail or opened a Pandora’s box? by Alkora Ioana Balan, Alina Scridon

“…Altered expression of different miRNAs has been related to proarrhythmic changes in the duration of action potentials and atrial fibrosis. In clinical studies, miRNA changes have been associated with AF, whereas in experimental studies miRNA manipulation has emerged as a potential therapeutic approach. …”
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Suvorexant, a Novel Dual Orexin Receptor Antagonist, for the Management of Insomnia by Andrew H. Han, Caroline R. Burroughs, Evan P. Falgoust, Jamal Hasoon, Grace Hunt, Juyeon Kakazu, Tim Lee, Adam M. Kaye, Alan D. Kaye, Latha Ganti

“…While there are many existing treatments such as benzodiazepines, melatonin agonists, TCAs, and atypical antipsychotics used to target various receptors involved in normal induction and maintenance of sleep, Suvorexant is an antagonist that specifically targets orexin receptors. Recent clinical studies suggest that Suvorexant is both clinically safe and effective. …”
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Genotypic Investigation of Clostridium difficile in Prince Edward Island by H Martin, LP Abbott, DE Low, B Willey, M Mulvey, J Scott Weese

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The impact of vitamin D on breast cancer treatment: Literature review by Fedosenko Mariia

“…Methods: The authors analyzed and systematized research data on the predictive effect of vitamin D on the prognosis and course of breast cancer, the manifestation of its "non-classical" effects in preclinical and clinical studies, and assessed the possible practical application of the results obtained at the molecular-cellular level. …”
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A Review of Ecological Factors Associated with the Epidemiology of Wildlife Trypanosomiasis in the Luangwa and Zambezi Valley Ecosystems of Zambia by Hetron Mweemba Munang'andu, Victor Siamudaala, Musso Munyeme, King Shimumbo Nalubamba

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Noncoding RNAs Associated with PPARs in Etiology of MAFLD as a Novel Approach for Therapeutics Targets by Fatemeh Kazeminasab, Maryam Baharlooie, Kamran Ghaedi

“…This study revealed a subset of ncRNAs that could help in more clear and guided designation of preclinical and clinical studies to verify the therapeutic application of the revealed ncRNAs by manipulating the PPARs molecular mechanism in MAFLD.…”
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Charles Bonnet syndrome in patients with geographic atrophy secondary to age-related macular degeneration: a cross-sectional study by Nathalie Skovgaard Eriksen, Nabi Mousavi, Yousif Subhi, Torben Lykke Sørensen, Marie Krogh Nielsen

“…Methods: A total of 149 patients with GA secondary to AMD were previously screened and examined for clinical studies. These patients were then prospective contacted by telephone for this study, and 120 patients responded and agreed to do an interview on symptoms of CBS. …”
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Effects of health education using mobile technologies on caregivers’ knowledge of routine growth monitoring for children aged 9 to 24 months in Kenya by Justus O. S. Osero, Edna N. Osano

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Exploring the Psychological Side of Fentanyl: A Scoping Review to Disclose the Psychosocial Dimensions of Illicitly Manufactured Fentanyl Users by Pasquale Caponnetto, Sergio Triscari, Graziella Chiara Prezzavento, Giorgia Farrugio, Chiara Farrauto, Simona Lanzafame, Giulia Schilirò, Eleonora Uccelli, Noemi Maria Vitale, Abdulnaser Fakhrou, Karim Nagi, Carmen Concerto

“…The majority of clinical studies on fentanyl have focused on its medical and biological aspects, particularly its addictive properties. …”
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Functional food products in Japan: A review by Shun Iwatani, Naoyuki Yamamoto

“…The new functional regulatory system is more flexible in terms of health claims, the protocol for clinical studies, and the required results. Therefore, the market for new regulatory products is still growing. …”
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