Perinatal Outcome of Fetal Echogenic Bowel: A Single-Center Retrospective Cohort Study by Hidayet Sal, Erhan Huseyin Comert, Yasin Semih Ekici, Turhan Aran

“…Conclusion: Isolated fetal echogenic bowel which can be considered as a soft marker for aneuploidy may be associated with lactose intolerance and celiac disease. Further clinical studies are warranted to evaluate this relationship. …”
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In Vitro Antimicrobial Activity of the Hydroalcoholic Extract of the Leaves of Myrcianthes hallii on Proteus spp by Abdel Bermúdez Sol, María José Goyes Baca, Diego Fernando Salazar Martínez

“…It is necessary to continue with clinical studies for its future use in medical formulations.…”
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Mesenchymal stem cells derived exosomes: a new era in cardiac regeneration by Hossein Rayat Pisheh, Mahsa Sani

“…We discuss the molecular mechanisms underlying their cardioprotective effects, summarize preclinical and clinical studies investigating their efficacy, and address the challenges and future perspectives of exosome-based therapies. …”
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Clinical advances in antibody-drug conjugates for hematological malignancies by TANG Sijie, MI Jianqing

“…Additionally, ADCs targeting different antigens such as CD123, CD19, CD20, receptor tyrosine kinase-like orphan receptor 1 (ROR1), and CD38 are undergoing clinical studies. Globally, there are over a hundred ADCs in development, and it is hoped that more breakthroughs will be achieved in the future to further optimize the treatment strategies for hematologic malignancies.…”
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Syndrome of excessive anterior lens capsule contraction in pseudophakic eyes by V.E. Korelina, E.V. Samkovich

“…The article describes the risk factors for the development of excessive anterior lens capsule contraction syndrome, such as pseudoexfoliation syndrome (PES), glaucoma, retinal dystrophy, high degree myopia and hypermetropia, uveitis, post-traumatic conditions. The data of clinical studies are given proving the necessity of the prevention of fibrosis of the anterior lens capsule when several risk factors are combined in one eye. …”
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G Protein-Coupled Estrogen Receptor-Selective Ligands Modulate Endometrial Tumor Growth by Whitney K. Petrie, Megan K. Dennis, Chelin Hu, Donghai Dai, Jeffrey B. Arterburn, Harriet O. Smith, Helen J. Hathaway, Eric R. Prossnitz

“…Moreover, our findings shed light on the potential mechanisms of SERM/SERD side effects reported in many clinical studies. Finally, our results provide the first demonstration that pharmacological inhibition of GPER activity in vivo prevents estrogen-mediated tumor growth.…”
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Helicobacter pylori Infection and Anemia in Taiwanese Adults by Hsiang-Yao Shih, Fu-Chen Kuo, Sophie S. W. Wang, Yi-Chang Liu, Meng-Chieh Wu, Yang-Pei Chang, Guei-Fen Chiu, Pi-Yu Chang, Deng-Chyang Wu, Ming-Chia Hsieh, Yao-Li Chen

“…The levels of hemoglobin, serum iron and ferritin, and TIBC remain unaffected after chronic H.p infection. Large-scale clinical studies are needed to prove the association.…”
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Branched-Chain Amino Acids (BCAAs): Revisiting Their Role in Sport and Health by Aleksandra Kajtel, Anna Skowronek, Martyna Piekarska, Katarzyna Dąbek, Michał Ochwat, Maria Sudoł, Gabriela Mierzwa

“…BCAA metabolism primarily occurs in skeletal muscle and liver, with leucine activating key signaling pathways like mTORC1, promoting muscle growth and reducing protein breakdown. Clinical studies demonstrate the potential benefits of BCAA supplementation, particularly when combined with resistance exercise, in improving muscle quality and functional outcomes. …”
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Nursing staff and supervisors perceptions on stress and resilience: a qualitative study by Madeleine Helaß, Anja Greinacher, Melanie Genrich, Andreas Müller, Peter Angerer, Harald Gündel, Florian Junne, Christoph Nikendei, Imad Maatouk

“…Trail registration The study was registered with the German Register for Clinical Studies (DRKS 00013482) on 09 March 2018.…”
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Advancing the Fight Against Cervical Cancer: The Promise of Therapeutic HPV Vaccines by Qian Zheng, Misi He, Zejia Mao, Yue Huang, Xiuying Li, Ling Long, Mingfang Guo, Dongling Zou

“…This review focuses on clinical studies involving therapeutic HPV vaccines for cervical cancer, specifically in three key areas: the treatment of cervical intraepithelial neoplasia; the treatment of cervical cancer in combination with or without chemotherapy, radiotherapy, or immune checkpoint inhibitors; and the role of prophylaxis following completion of treatment. …”
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Effectiveness of acupuncture for equine laminitis: Systematic review and meta-analysis by Faisal Fikri, Agus Purnomo, Salipudin Tasil Maslamama, Muhammad Thohawi Elziyad Purnama

“…Conclusion: This meta-analysis enhanced the clinical studies demonstrating that twice-weekly acupuncture performed for 4 weeks consecutively can ameliorate lameness scores and a horse’s potential for recovery. …”
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Three-dimensional dynamics of mesothelin-targeted CAR.CIK lymphocytes against ovarian cancer peritoneal carcinomatosis by Federica Galvagno, Valeria Leuci, Annamaria Massa, Chiara Donini, Ramona Rotolo, Sonia Capellero, Alessia Proment, Letizia Vitali, Andrea Maria Lombardi, Valentina Tuninetti, Lorenzo D’Ambrosio, Alessandra Merlini, Elisa Vigna, Giorgio Valabrega, Luca Primo, Alberto Puliafito, Dario Sangiolo

“…Our findings provide currently unknown therapeutically relevant information on intraperitoneal approaches with CAR.CIK, supporting further developments and improvements for clinical studies in the context of locoregional cell therapy approaches for patients with PC from OC.…”
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Systemic inflammatory response index improves prognostic predictive value in intensive care unit patients with sepsis by Tuo Xu, Shuaiwei Song, Ke Zhu, Yin Yang, Chengyu Wu, Naixue Wang, Shu Lu

“…SIRI may serve as a novel prognostic indicator in sepsis, though further clinical studies are necessary to confirm these findings.…”
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The clinical application of artificial intelligence in cancer precision treatment by Jinyu Wang, Ziyi Zeng, Zehua Li, Guangyue Liu, Shunhong Zhang, Chenchen Luo, Saidi Hu, Siran Wan, Linyong Zhao

“…Conclusions Recent clinical studies demonstrate that artificial intelligence is involved in cancer precision medicine and has the potential to benefit cancer healthcare, particularly by optimizing conventional therapies, emerging targeted therapies, and individual immunotherapies. …”
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Simultaneous Quantification of Aspirin, Its Metabolite Salicylic Acid, and Salvianolic Acid B in Human Plasma Using UPLC-MS/MS by Weiyi Cao, Hezhi Yao, Zhenzhen Qian, Yi Wu, Shuge Wang, Rui Li, Rui Gao

“…Clinically, salvianolate injection and aspirin are commonly combined to treat coronary heart diseases in patients with stable angina. To support clinical studies on drug-drug interactions (DDIs) between salvianolate injection and aspirin, a rapid and sensitive UPLC-MS/MS method for the simultaneous determination of aspirin (acetylsalicylic acid), its metabolite salicylic acid, and salvianolic acid B in human plasma was developed. …”
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The Efficacy of Chimeric Antigen Therapy in Viral Infectious Diseases: A Systematic Review of Randomized Controlled Trials by Hossein Hatami, Elnaz Ataei, Mohammadjavad Nasiri, Hamed Ghorani

“…To maximize the efficacy of CAR T-cell therapy and clarify its long-term effectiveness in the treatment of infectious diseases, more investigation and clinical studies are required.…”
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The impact of absorbable hemostatic agents on wound healing in an experimental penile fracture rat model by Mehmet Ezer, Engin Doğantekin, Muzaffer Çaydere, Aykut Koç, Çağrı Öktem, Sema Hücümenoğlu

“…These findings suggest that ORC may have potential clinical applications in penile fracture repair. Further clinical studies are necessary to validate these results.…”
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Dietary Variations in a Multiethnic Parkinson’s Disease Cohort and Possible Influences on Nonmotor Aspects: A Cross-Sectional Multicentre Study by Anna Sauerbier, Anette Schrag, Pablo Martinez-Martin, Lynsey J. Hall, Miriam Parry, Laurie K. Mischley, Panagiotis Zis, K. Ray Chaudhuri

“…These data support the importance of considering ethnic diversity as part of recruitment strategy in nutrition and clinical studies.…”
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Description of Methodology for Testing the Synergistic and Additive Effects of Antibiotics in Vitro by Kmiecikowski Paweł Z., Gabriel Aniela, Depka Dagmara, Bogiel Tomasz

“…This paper reviews the latest literature on methods for determining the antimicrobials interactions. Clinical studies indicate significant benefits of using the phenomenon of antibiotic addition or synergy in clinical practice, not only improving the effectiveness of therapy, but also minimizing side effects and reducing the risk of developing de novo antibiotic resistance. …”
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Targeted Regulation Of Cgrp Gene Expression by A. F. Russo, P. L. Durham

“…The neuropeptide calcitonin gene-related peptide (CGRP) is a potent regulator of cerebral vascular tone and contributes to neurogenic inflammation. Clinical studies have shown that CGRP levels are elevated during the painful phase of migraine headache, then restored to baseline by antimigraine 5-HT1 drugs. …”
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