To Evaluate and Compare the Microleakage of Chitosan Nano Hydrogel-Incorporated MTA and Glass Ionomer Cements When used as a Retrograde Filling Material by Vinaykumar G. Suryavanshi, Ravi K. Tale, Vivekanand D. Kolvekar, Rashmi Chordiya, P S Amal, B Abijeet

“…Conclusion: Chitosan-incorporated MTA and chitosan-incorporated GIC can be considered as retrograde filling material; however, further in vitro and in vivo research and long-term clinical studies are required.…”
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Emerging Evidence concerning the Role of Sirtuins in Sepsis by Lulan Li, Zhongqing Chen, Weijun Fu, Shumin Cai, Zhenhua Zeng

“…Though experimental and clinical studies relating to sepsis are increasing, the mechanism of sepsis is not completely understood. …”
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Symptomatic tensor fasciae suralis muscle as accessory muscle at popliteal fossa in young soldier: a case report by Yong Sik Lee, Yeong Hyeon Lee, Jee Soo Park, Gil Yeong Ahn, Sung Hyun Hwang, Chae Kyung Lee

“…Abstract Introduction The tensor fasciae suralis is an aberrant muscle frequently identified in cadaveric studies and MRI studies; however, it has been rarely reported in clinical studies. We present a case of recurrent popliteal pain in a young adult male and our experience with its diagnosis and treatment. …”
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Application of in vitro and in vivo models in the study of food allergy by Jianjian Huang, Changjun Liu, Yanbo Wang, Chong Wang, Menghua Xie, Yi Qian, Linglin Fu

“…Keywords: Food allergy, Cell model, Animal model, Zebrafish, Clinical study…”
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Cardiac Markers in Pediatric Laboratory Medicine: Critical Review by Renata Zrinski Topic, Jasna Lenicek Krleza

“…The results from the studies on reference values, as well as results from clinical studies, are difficult to compare with identical studies due to the heterogeneity of subject characteristics (gestational and chronological age, sex, pubertal status, menstrual cycle, exercise), assay characteristics (type of assay, generation of assay, analytical platform used), and experimental protocol characteristics (prospective or retrospective studies, reference population selection, patient population selection, inclusion and exclusion criteria, number of subjects). …”
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Cavernous Nerve Injury Resulted Erectile Dysfunction and Regeneration by Nan Jiang, Cheng Wu, Xunrong Zhou, Guanghua Zhai, Jian Wu

“…In addition, such as neuromodulatory proteins, proimmune ligands, gene therapy, stem cell therapy, and the current cutting-edge low-energy shock wave therapy have shown advantages in basic research and limited clinical studies. In the context of today’s modern medicine, these new therapeutic techniques are expected to be new tools in the treatment of cavernous nerve injury erectile dysfunction. …”
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Micropower Impulse Radar: A Novel Technology for Rapid, Real-Time Detection of Pneumothorax by Phillip D. Levy, Tracey Wielinski, Alan Greszler

“…Post market studies are planned starting in May of 2011. Clinical studies to support the FDA submission will be completed in the first quarter of 2012.…”
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Determination of Probiotics Prescription Indications in Patients with Irritable Bowel Syndrome (Materials of the Expert Council and Literature Review) by V. T. Ivashkin, I. V. Maev, O. P. Alekseeva, S. A. Alekseenko, N. V. Korochanskaya, E. A. Poluektova, V. I. Simanenkov, A. S. Trukhmanov, I. B. Khlynov, V. V. Tsukanov, O. S. Shifrin, T. L. Lapina, R. V. Maslennikov, A. I. Ulyanin

“…The optimal probiotic should be effective, safe, strain-specific, and its dose and duration of administration should be confirmed by the results of clinical studies. Some of the probiotics with proven efficacy in IBS are Alflorex® and Enterol®.Conclusion. …”
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Pantoprazole – safety in drug-drug interaction by E. V. Shikh, D. A. Sychev

“…This is proved by relative safety of clopidogrel to pantoprazole combination in patients with cardio-vascular diseases, demonstrated in clinical studies of the last years.Conclusion. Data of investigations, available for the present time, in vitro and in vivo allow to consider pantoprazole (Nolpaza) as the most safe drug for application in complex therapy to reduce the drug interaction-associated adverse effects.…”
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Rotate-on-Retract Procedural Automation for Robotic-Assisted Percutaneous Coronary Intervention: First Clinical Experience by Arif Al Nooryani, Wael Aboushokka

“…Favorable results in several clinical studies suggest that robotic-assisted PCI may further improve patient outcomes while also benefiting the interventionalist through reduced orthopedic strain and less exposure to ionizing radiation. …”
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Clinical outcomes of a hydrophobic trifocal diffractive intraocular lens: a literature review by Deborah Ristvedt, Camille Bosc, Vance Thompson, Vance Thompson

“…National Library of Medicine) was performed to identify publications, both prospective and retrospective, which have reported the clinical outcomes of patients who were implanted with this IOL model after cataract or refractive lens exchange surgeries. A total of 18 clinical studies published between 2019 and 2024 were included in this review. …”
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Potential renoprotective effects and possible underlying mechanisms of angiotensin receptor-neprilysin inhibitors in cardiorenal syndrome by Md. Moshiur Rahman, Md. Moshiur Rahman, Asadur Rahman, Akira Nishiyama

“…Altogether, the analysis of published data from both pre-clinical and clinical studies provides substantial support for the usefulness of ARNIs in enhancing renal protection in subjects with CRS.…”
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Treatment of irritable bowel syndrome: the past, present and future by V. T. Ivashkin, Ye. A. Poluektova, O. S. Lyashenko, D. V. Reykhart

“…To present data on foreign and Russian clinical studies devoted to improvement of irritable bowel syndrome (IBS) treatment according to the new data on disease pathogenesis.Summary. …”
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Aldosterone and Its Blockade: A Cardiovascular and Renal Perspective by V. Lahera, V. Cachofeiro, G. Balfagon, J.L. Rodicio

“…Numerous experimental and clinical studies indicate that aldosterone participate in cardiac alterations associated with hypertension, heart failure, diabetes and other pathological entities. …”
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Oligonucleotides as a Novel Therapeutic Approach: An Innovative Area for Drug Delivery in Neurological Disorders by Yasir Qasim Almajidi, Rana Kadum Muslim, Yaseen T. khalf

“…Ongoing preclinical and clinical studies are assessing the safety and efficacy of Antisense Oligonucleotide) ASOs (in multiple genetic and acquired neurological conditions. …”
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Fetal and Neonatal Levels of Omega-3: Effects on Neurodevelopment, Nutrition, and Growth by Juliana Rombaldi Bernardi, Renata de Souza Escobar, Charles Francisco Ferreira, Patrícia Pelufo Silveira

“…Preclinical and clinical studies suggest the role of n-3 LCPUFAs on neurodevelopment and growth. n-3 LCPUFAs may be an effective adjunctive factor for neural development, growth, and cognitive development, but further large-scale, well-controlled trials and preclinical studies are needed to examine its clinical mechanisms and possible benefits. …”
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New Photosensitizers for Photodynamic Therapy in Gastroenterology by SG Bown, AZ Rogowska

“…This makes it feasible to destroy areas of abnormal mucosa without damaging the underlying muscle and is, therefore, better for treating Barrett’s esophagus. Detailed clinical studies are required to establish the real role of PDT with the use of these and other new photosensitizers.…”
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Gastroesophageal Reflux Disease and Tooth Erosion by Sarbin Ranjitkar, John A. Kaidonis, Roger J. Smales

“…Though increasing evidence of associations between GERD and tooth erosion has been shown in both animal and human studies, relatively few clinical studies have been carried out under controlled trial conditions. …”
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Impact of the Ketogenic Diet on Neurological Diseases: A Review by Carmen Rubio, Alejandro López-Landa, Hector Romo-Parra, Moisés Rubio-Osornio

“…Conclusion: Multiple molecular mechanisms have been identified to explain the benefits of the KD in neurological diseases; however, further experimental and clinical studies are needed to address various molecular pathways in order to achieve conclusive results.…”
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Brain-Derived Neurotrophic Factor and Nerve Growth Factor Therapeutics for Brain Injury: The Current Translational Challenges in Preclinical and Clinical Research by Serena-Kaye Sims, Brynna Wilken-Resman, Crystal J. Smith, Ashley Mitchell, Lilly McGonegal, Catrina Sims-Robinson

“…BDNF and NGF have demonstrated the ability to improve functional recovery in preclinical and to a lesser extent clinical studies. Direct and indirect methods to increase levels of neurotrophic factors in animal models have been successful in improving postinjury outcome measures. …”
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