Rationale and design of the multicenter, national, randomized, open labeled phase III trial: allogeneic stem cell transplantation as a potential curative treatment for patients wit... by Annemarie Glöckner, Stefan Schönland, Hermann Einsele, Nicolaus Kröger

“…Discussion The present clinical study is designed to evaluate the superiority of allogeneic stem cell transplantation compared to conventional therapy (triplet chemotherapy) for the difference in overall survival at 5 years, toxicity and quality of life in patients with multiple myeloma who have relapsed or progressed after first-line autologous stem cell therapy. …”
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Romanian validation study of the Boston questionare in patients with carpal tunnel syndrome by Lenuța Bîrsanu, Roxana Covali, Emanuel Matei Roman, Ioan Alexandru Chirap-Mitulschi, Alin Ciubotaru, Mihaela-Dana Turliuc

“…We conducted a two-parts study: the first part involved the translation and cross-cultural adaptation of the The Boston Carpal Tunnel Questionnaire -Romanian version, while the second part was a prospective cohort clinical study that was designed to psychometrically validate the The Boston Carpal Tunnel Questionnaire. …”
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Clinical Evaluation of the 3nethra Aberro Handheld Autorefractometer by Selvamani Perumal, Surya Venkatramanan, Venkatramanan RJ, Jayanthi T, Jai Adithya, Anjaly Abraham, Henna Cherian

“…The resultant power vectors were compared with subjective measurements. Results: This clinical study comprised 60 subjects (22 male and 38 female; with a mean age of 34 ± 16 years). …”
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Extracorporeal Shock Waves Therapy for the Treatment of Acute and Chronic Wounds—A Prospective, Monocentric Clinical Trial to Examine the Effect of Shock Waves on Wound Healing by Kristina Landscheidt, Ahmed Alabdulmohsen, Markus Hübscher, Benjamin Geber, Jochen‐Frederick Hernekamp, Ole Goertz

“…ABSTRACT Introduction The aim of our prospective blinded clinical study was to examine a possible improvement and acceleration of epithelialization by treatment with low‐energy extracorporeal shock waves on skin graft donor and recipient sites in patients with chronic wounds. …”
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Effects of Retinol, Natural Pea Peptide and Antioxidant Blend in a Topical Formulation: In Vitro and Clinical Evidence by Brian Cook, Melanie Riggs, K. C. Holley, Helen Knaggs, Ganesh Diwakar, Edwin D. Lephart

“…Methods In vitro assessment of RTF on human skin co-cultures (human keratinocytes, melanocytes, and dermal fibroblasts) identified gene expression levels and skin biomarkers after 24 h exposure. An 8-week clinical study was conducted to evaluate once-nightly application of the RTF for short-term and long-term benefits in 30 adult subjects between 35 and 70 years of age (21 female, 9 male). …”
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The Efficacy of Intravitreal Conbercept for Chronic Central Serous Chorioretinopathy by Jianbo Mao, Caiyun Zhang, Chenyi Liu, Lijun Shen, Jimeng Lao, Yirun Shao, Yiqi Chen, Jiwei Tao

“…Methods. A retrospective clinical study. Thirty-one patients (35 eyes) with chronic CSC were given intravitreal injections of conbercept and followed up for at least 6 months. …”
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Case report: A rare case of delayed drug-induced hyponatremia in recurrent upper tract urothelial carcinoma following GC and Tislelizumab treatment by Zhi-Jie Wang, Zhi-Jie Wang, Ying-Fang Nie, Shi-Bing Liang, Shi-Bing Liang, Shi-Bing Liang, Jing Zhou, Shu-Lan Hao, Li-Kun Liu

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Three-Month Outcomes of SMILE Pro with the VISUMAX 800 for Myopic Astigmatism in a Large Population by Cung HS, Tran LHT, Tran TN

“…Hong Son Cung,1,2 Lan Huong Thi Tran,1,2 Thanh Ngoc Tran1,2 1Vietnam National Eye Hospital, Ha Noi, Vietnam; 2Hong Son Eye Hospital, Ha Noi, VietnamCorrespondence: Lan Huong Thi Tran, Vietnam National Eye Hospital, Ha Noi, Vietnam, Email huonglanmat1991@gmail.comPurpose: To report the visual and refractive outcomes of small-incision lenticule extraction (SMILE) Pro using a 2 MHz femtosecond laser for myopic astigmatism in a large population of Vietnamese patients.Methods: This was a retrospective clinical study of subjects that underwent keratorefractive lenticule extraction (KLEx) with the VISUMAX 800 at Hong Son Eye Hospital (Ha Noi, Vietnam) between June 2023 and October 2023. …”
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Relationship between the Plasma Levels of Catecholamines and Return of Spontaneous Circulation in Patients with Out-of-Hospital Cardiac Arrest by Yumi Ichikawa, Yusuke Sawada, Jun Nakajima, Yuta Isshiki, Kazunori Fukushima, Yuto Aramaki, Kiyohiro Oshima

“…This was a prospective, observational clinical study. Patients with OHCA transferred to our hospital between July 2014 and July 2017 were enrolled. …”
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A pilot, four-week, dietary program with targeted nutraceuticals improves cardiometabolic functioning, metabolic transformation, and gut health by Wei Gao, Joseph J. Lamb, David Graham, Bhargavi Manda, Clinton J. Dahlberg, E. Wesley Huff, Michael Saunders, Matthew L. Tripp

“…We conducted this 4-week, observational, clinical study to explore the safety and efficacy of a proprietary dietary program formulated to enhance cardiometabolic functioning, metabolic transformation, and gut health. …”
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FGF2 and EGF for the Regeneration of Tympanic Membrane: A Systematic Review by Zhengcai Lou, Zihan Lou, Yumeng Jiang, Zhengnong Chen

“…Two clinical studies showed similar closure rates between groups treated with FGF2 and EGF. …”
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Injectable Chitosan Hydrogel Particles as Nasal Packing Materials After Endoscopic Sinus Surgery for Treatment of Chronic Sinusitis by Yusuke Yamashita, Kei Hosoya, Yukio Fujiwara, Yoichi Saito, Masahiro Yoshida, Shoji Matsune, Kimihiro Okubo, Takayuki Takei

“…Additionally, we applied the injectable chitosan hydrogel particles as nasal packing materials to patients with bilateral chronic sinusitis undergoing ESS in a pilot clinical study. Concerning symptom scores, though the results narrowly missed statistical differences (<i>p</i> < 0.05), the average scores of our chitosan hydrogel were superior to those of a commercially available wound dressing (especially <i>p</i> = 0.09 for nasal bleeding). …”
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Evaluation of Risk Factors for Antibiotic Resistance in Patients with Nosocomial Infections Caused by Pseudomonas aeruginosa by Meliha Cagla Sonmezer, Gunay Ertem, Fatma Sebnem Erdinc, Esra Kaya Kilic, Necla Tulek, Ali Adiloglu, Cigdem Hatipoglu

“…Pseudomonas aeruginosa (P. aeruginosa) is resistant to various antibiotics and can cause serious nosocomial infections with high morbidity and mortality. In this clinical study, we investigated the risk factors in patients who were diagnosed with P. aeruginosa-related nosocomial infection. …”
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Challenges in the Management of Giant Carcinoma Ex-Pleiomorphic Adenoma of the Parotid Gland in a Single Tertiary Center by Miruna Bratiloveanu, Mihai Dumitru, Andreea Nicoleta Marinescu, Crenguta Serboiu, Oana Maria Patrascu, Adrian Costache, Daniela Vrinceanu

“…<i>Materials and Methods:</i> We performed a retrospective clinical study over the period of 2009–2023 in patients admitted to the ENT Department of the Bucharest University Emergency Hospital. …”
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Reactive Metabolites and AGE-RAGE-Mediated Inflammation in Patients following Liver Transplantation by Thorsten Brenner, Thomas H. Fleming, David Spranz, Peter Schemmer, Thomas Bruckner, Florian Uhle, Eike O. Martin, Markus A. Weigand, Stefan Hofer

“…In this observational clinical study, 150 patients were enrolled following liver transplantation from deceased donors. …”
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Validation of clinical T stage using depth of invasion in the patients with oral squamous cell carcinoma and its correlation with imaging by Mahesh Sultania, Priyansh Jain, Itisha Chaudhary, Hemanth Ghalige, Simran Sidhu, Sudipta Mohakud, G. Sudhakar, K. Raghuram, Dillip Muduly, Amit Adhya, Sandip Barik, Saroj Majumdar, Madhabananda Kar

“…Materials and methods: This was a prospective clinical study carried out from December 2019 to June 2023 at an academic tertiary care centre. …”
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Efficacy of various combined treatment regimens in patients with stable effort angina, functional classes II-III by Svetlana G. Dorofeeva, Eugenia N. Konoplya, Oksana V. Mansimova

“…Materials and Methods: The clinical study included 120 patients diagnosed with coronary heart disease: stable effort angina, functional classes II–III, and 40 healthy participants who met the inclusion criteria. …”
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Orthodontic and orthopedic rehabilitation of adult patients with congenital cleft lip and palate (clinical case) by L.B. Halych, V.D. Kuroyedova, N.V. Tsvetkova, L.V. Halych

“…Congenital cleft lip, alveolar process, hard and soft palate are common anomalies of the development of human organs and in terms of frequency occupy one of the first places among other defects of the human body. The clinical study and treatment of cleft lip and palate, malocclusions that accompany this defect have always been of great interest in orthodontics and orthopedic dentistry. …”
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A Comparative Evaluation of the Efficacy of Two Novel Desensitising Dentifrices by Ashley P. Barlow, Jane He, Cindy Tian, Peter Jeffery, Stephen C. Mason, Bao-Jun Tai, Han Jiang, Gareth D. Rees, Min Quan Du

“…A comparison of the desensitising efficacy of two commercially available dentifrices with different modes of action was conducted in a randomised, examiner-blind, two-arm, parallel group, 8-week, longitudinal clinical study. Dentifrice A, (Sensodyne Multi Action Iso-Active), contained 50000 ppm KNO3 and 1450 ppm fluoride as NaF. …”
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Impact of a synchronous prophylactic treatment of the anterior accessory saphenous vein on the recurrent varicose vein rate in patients undergoing thermal ablation of an insufficie... by Lorenz Uhlmann, Christine Fink, Karsten Hartmann, Thomas Mattausch, Hans-Christian Wenzel, Phillip Zollmann, Jürgen Veltman, Thomas Weiler, Guido Lengfellner, Lars Müller, Markus Stücker, Felizitas Pannier, Carmen Dietrich, Tobias Hirsch

“…Additionally, it will be clarified whether patients benefit from a preventive ablation of a sufficient AASV.Methods and analysis This is a multicentre, prospective, controlled, exploratory clinical study in 1150 patients with a medical indication for EVLA of a refluxing great saphenous vein. …”
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