The Role of Adipose-Derived Stem Cells in Breast Cancer Progression and Metastasis by Riccardo Schweizer, Wakako Tsuji, Vijay S. Gorantla, Kacey G. Marra, J. Peter Rubin, Jan A. Plock

“…Thus far, preclinical and clinical study findings are discordant. A trend towards potential promotion of both breast cancer growth and invasion by ADSCs found in basic science studies was indeed not confirmed in clinical trials. …”
Get full text

Platelet Indices in Colorectal Cancer Patients with Synchronous Liver Metastases by Li Li, Xiao-Yi Huang, Na Li, Ming-ming Cui, Rui-tao Wang

“…We conducted a retrospective clinical study including 206 CRC patients without metastases and 200 CRC patients with synchronous liver metastases from January 1, 2015, to December 31, 2017. …”
Get full text

An Aloe-Based Composition Constituting Polysaccharides and Polyphenols Protected Mice against D-Galactose-Induced Immunosenescence by Mesfin Yimam, Teresa Horm, Alexandria O’Neal, Ping Jiao, Mei Hong, Qi Jia

“…These data warrant further clinical study to explore the potential application of the mushroom-based composition as an adjunct nutritional supplement for a balanced immune response.…”
Get full text

Posterior Transpedicular Dynamic Stabilization versus Total Disc Replacement in the Treatment of Lumbar Painful Degenerative Disc Disease: A Comparison of Clinical Results by Tunc Oktenoglu, Ali Fahir Ozer, Mehdi Sasani, Yaprak Ataker, Cengiz Gomleksiz, Irfan Celebi

“…Study Design. Prospective clinical study. Objective. This study compares the clinical results of anterior lumbar total disc replacement and posterior transpedicular dynamic stabilization in the treatment of degenerative disc disease. …”
Get full text

Role of Adult Asthma Education in Improving Asthma Control and Reducing Emergency Room Utilization and Hospital Admissions in an Inner City Hospital by Rashmi Mishra, Muhammad Kashif, Sindhaghatta Venkatram, Teresa George, Kristina Luo, Gilda Diaz-Fuentes

“…Institutional Review Board Clinical Study registration number is 01081507.…”
Get full text

Vacuum-Assisted Continuous Circular Capsulorhexis Using Bimanual Irrigation and Aspiration System of Phaco Machine in Immature Cataract by Huseyin Oksuz, Mutlu C. Daglioglu, Mesut Coskun, Özgür İlhan, Esra Ayhan Tuzcu, Nilufer Ilhan, Emre Ayıntap, Uğurcan Keskin, İbrahim Taşkın

“…Seventy-eight eye of 65 patients were enrolled in this retrospective clinical study. Two-side ports are made with a 23-gauge stiletto knife. …”
Get full text

Influence of Medication on Fatigue Six Months after Stroke by Amélie Ponchel, Julien Labreuche, Stéphanie Bombois, Christine Delmaire, Régis Bordet, Hilde Hénon

“…Our results suggest that PSF is not a side effect of drugs use, which more reflects presence of disturbances frequently observed after stroke such as depression, anxiety, or sleep disturbances. Clinical study is registered on clinicaltrials.gov (NCT01330160).…”
Get full text

Erenumab effectiveness and safety: comparison of real-life data and clinical trial results by Austėja Dapkutė, K. Ryliškienė

“…Previously, evidence of the safety and efficacy of erenumab was supported only by clinical study results, but more recently, real-life data started to appear. …”
Get full text

Effects of maternal positions in electronic fetal monitoring: a randomised controlled trial by Tuğba Yilmaz Esencan, Ayça Demir Yildirim, Ebru Sağiroğlu

“…It is recommended that the semi-Fowler position be preferred for fetal monitoring in pregnant women with a high BMI, and further research should be conducted to make these positions standard in the clinic. Clinical Study Registration Since our research constituted a randomized controlled study, it was registered on the ClinicalTrials.gov website under ClinicalTrials ID No. …”
Get full text

Surgical management of single-level thoracolumbar vertebral body segmentation and formation failure causing progressive thoracolumbar myelopathy in three adult large-breed dogs by Francisca Couto, Joana Tabanez, Jeremy Rose, Colin Driver

“…ObjectiveThis study aimed to evaluate the medium-term outcome following spinal cord decompression and instrumented fixation of single-level congenital thoracolumbar vertebral malformations, characterized by combined failures of segmentation and formation, causing thoracolumbar myelopathy in three large-breed dogs.Study designThis was a retrospective clinical study.AnimalsThe animals involved in the study were three large-breed dogs.MethodsElectronic patient records were retrospectively reviewed for adult large-breed dogs (>1 year) (>25 kg) with thoracolumbar myelopathy and a radiologic diagnosis of spinal cord compression associated with thoracolumbar vertebral malformation. …”
Get full text

The Effect of Platelet-Rich Fibrin (PRF) in Accelerating Periodontal Regeneration: A Randomized Controlled Clinical Trial by Ashwini Dhopte, Konsam Bidya Devi, KS Pandaw, Anamika Rani, Sachin Chand, Hiroj Bagde

“…Materials and Methods: The randomized controlled clinical study included a cohort of 60 individuals diagnosed with chronic periodontitis. …”
Get full text

Descrição dos primeiros recém-nascidos monitorizados por meio de eletroencefalograma de amplitude integrada em uma maternidade privada do Nordeste do Brasil by Lucas Rocha Barreto de Almeida, Marcos Alves Pavione, Arnon Silva de Carvalho, Gabriel Fernando Todeschi Variane

“…METHODOLOGY: This was an observational, descriptive, and cross-sectional clinical study. A convenience sample was used, including all sequential newborns submitted to neuromonitoring from February 2021 to June 2022. …”
Get full text

Novel Design on Knee Exoskeleton with Compliant Actuator for Post-Stroke Rehabilitation by Lin Wu, Chao Wang, Jiawei Liu, Benjian Zou, Samit Chakrabarty, Tianzhe Bao, Sheng Quan Xie

“…A variable impedance control method was also implemented to achieve accurate position tracking of the exoskeleton, and performance tests were conducted with and without human participants. A preliminary clinical study involving two stroke patients demonstrated the exoskeleton’s potential in reducing muscle spasticity, particularly at faster movement velocities. …”
Get full text

Enavatuzumab, a Humanized Anti-TWEAK Receptor Monoclonal Antibody, Exerts Antitumor Activity through Attracting and Activating Innate Immune Effector Cells by Shiming Ye, Melvin I. Fox, Nicole A. Belmar, Mien Sho, Debra T. Chao, Donghee Choi, Yuni Fang, Vivian Zhao, Stephen F. Keller, Gary C. Starling, Patricia A. Culp

“…Enavatuzumab is a humanized IgG1 anti-TWEAK receptor monoclonal antibody that was evaluated in a phase I clinical study for the treatment of solid malignancies. …”
Get full text

Application of Anterior Segment Optical Coherence Tomography in Pediatric Ophthalmology by Ricardo Salles Cauduro, Caroline do Amaral Ferraz, Maira Saad Ávila Morales, Patricia Novita Garcia, Yara Cristina Lopes, Paulo Henrique Souza, Norma Allemann

“…Methods. Retrospective clinical study case series of 26 eyes of 19 pediatric patients throughout a 21-month period, presenting anterior segment pathologies, were submitted to AS-OCT examination (OCT Visante, 1310 nm, Zeiss), noncontact technique, no sedation requirement. …”
Get full text

Comparison of the effects of lidocaine and articaine used for buccal infiltration and supplemental palatinal infiltration anesthesia in maxillary molars with irreversible pulpitis:... by Duygu Kolay, Damla Kırıcı

“…Material-methods This randomized clinical study was conducted on 80 patients with symptomatic irreversible pulpitis of the maxillary first and second molars. …”
Get full text

Detection of Cannabinoid Receptor Expression by Endometriotic Lesions in Women with Endometriosis as an Alternative to Opioid-Based Pain Medication by Sarah Allam, Elizabeth Paris, Itzel Lazcano, Pincas Bitterman, Sanjib Basu, James O’Donnell, Animesh Barua

“…These results will form a foundation for a clinical study with larger cohorts.…”
Get full text

The role of new hepatitis B vaccines in South Africa by G U van Zyl, T Maponga, H Rabie, J Taljaard

“…PreHevbrio, which includes three hepatitis B surface protein domains, instead of one, may also be more immunogenic, although clinical study data are still limited. These two novel vaccines have not yet been investigated in children and licensed in SA. …”
Get full text

Changes in Hepatic Blood Flow and Liver Function during Closed Abdominal Hyperthermic Intraperitoneal Chemotherapy following Cytoreduction Surgery by Stéphanie Dupont, Eduardo R. C. Schiffer, Marion J. White, John R. A. Diaper, Marc-Joseph Licker, Philippe C. Masouyé

“…In this prospective observational clinical study including 15 consecutive patients, we evaluated HBF by transesophageal echocardiography and liver function by determination of the indocyanine green plasma disappearance rate (ICG-PDR). …”
Get full text

Coronectomy versus total odontectomy of impacted lower third molars with close relation tothe inferior alveolar canal: An open clinical trial. by Hundren Muhammad, Rozh Mumtaz, Dilman Najmaddin, Omed Ikram

“…This study aims to evaluate the consequences of coronectomy compared to complete surgical removal in patients with a high risk of inferior alveolar nerve injury. Method: This clinical study is performed in the Department of Oral and Maxillofacial surgery, Dentistry College, Hawler Medical University. …”
Get full text