Costello Syndrome. A case report by Yadelis Maldonado Martínez, Alexander Torres Molina, Diorgis Duran Lobaina

“…The case of a 7-year-old patient from the Frank País municipality in Holguín with clinical manifestations consistent with Costello syndrome is presented. The clinical study and description of his physical characteristics were performed, detecting as main distinctive features: storage disease-like phenotype, failure to thrive, congenital heart disease, coarse facies, mental retardation and humorous personality. …”
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Double-Blind Clinical Trial of Arginine Supplementation in the Treatment of Adult Patients with Sickle Cell Anaemia by Renata M. N. Eleutério, Francisco O. Nascimento, Tamara G. Araújo, Marilena F. Castro, Tarcísio P. Almeida Filho, Pedro A. Maia Filho, José Eleutério, Darcielle B. D. Elias, Romélia P. G. Lemes

“…The clinical study enrolled 25 patients receiving HU + L-arginine (500 mg) and 25 patients receiving HU + placebo. …”
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Effects of Semaglutide Treatment on Psoriatic Lesions in Obese Patients with Type 2 Diabetes Mellitus: An Open-Label, Randomized Clinical Trial by Jelena Petković-Dabić, Ivana Binić, Bojana Carić, Ljiljana Božić, Sanja Umičević-Šipka, Nataša Bednarčuk, Saša Dabić, Mirna Šitum, Snježana Popović-Pejičić, Miloš P. Stojiljković, Ranko Škrbić

“…This randomized clinical study was conducted on 31 psoriatic patients with T2DM that were randomized into two groups: one that received semaglutide during the 12-week trial (<i>n</i> = 15), while the second was control (<i>n</i> = 16). …”
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Elevated plasma phospholipase A2 and platelet-activating factor acetylhydrolase activity in colorectal cancer by Yves Denizot, Véronique Truffinet, Stéphane Bouvier, Alain Gainant, Pierre Cubertafond, Muriel Mathonnet

“…This clinical study reports that blood levels of the pro-inflammatory mediator platelet-activating factor (PAF) did not change in colorectal cancer patients. …”
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Biostatistical Assessment of Mutagenicity Studies: A Stepwise Confidence Procedure by Michael J. Adjabui, Nathaniel K. Howard, Mathias Akamba

“…We illustrate our procedure with mutagenicity dataset from a clinical study.…”
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Research Progress on Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Knee Osteoarthritis by GONG Jin, ZHANG Jinjin, CHEN Lili, WANG Hui, XING Yanchao

“…This article synthesizes the latest research findings from both domestic and international sources to discuss the theoretical basis for the clinical application of hUC-MSCs in treating KOA, clinical study design, and efficacy evaluation. It also addresses the challenges in the clinical application of hUC-MSCs and explores future directions, in the hope of providing feasible theoretical support for the treatment of KOA with hUC-MSCs.…”
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Identification of Novel Mutations in Spatacsin and Apolipoprotein B Genes in a Patient with Spastic Paraplegia and Hypobetalipoproteinemia by Leema Reddy Peddareddygari, Raji P. Grewal

“…Our results indicate that, in this patient, the hypobetalipoproteinemia and spastic paraplegia are unrelated resulting from mutations in two independent genes. This clinical study provides support for the use of whole exome sequencing as a diagnostic tool for identification of mutations in conditions with complex presentations.…”
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Drug screening for ischemic stroke using larvae and adult zebrafish model: a review by Ni Made Dwi Mara Widyani Nayaka, I Ketut Adnyana, Kusnandar Anggadiredja, Indra Wibowo

“…Finally, this review offers future recommendations for the use of zebrafish in the pre-clinical study of IS. This review is beneficial as a reference for establishing drug screening protocols using the zebrafish IS model.…”
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Correlation between Hyperalgesia and Upregulation of TNF-α and IL-1β in Aqueous Humor and Blood in Second Eye Phacoemulsification: Clinical and Experimental Investigation by Ruibo Yang, Chang Liu, Di Yu, Lechong Ma, Yan Zhang, Shaozhen Zhao

“…TNF-α and IL-1β levels in AH and TNF-α mRNA and IL-1β mRNA levels in whole blood were measured. In a clinical study, 30 patients who underwent bilateral phacoemulsification within 1 month were divided into six groups in accordance with the operation intervals (1, 3, 7, 10, 14, and 21days). …”
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Community-Specific BMI Cutoff Points for South Indian Females by K. B. Kishore Mohan, V. Sapthagirivasan, M. Anburajan

“…A total number of 87 females (of age 37.33±13.12 years) from South Indian Chennai urban population participated in this clinical study. Body composition analysis and anthropometric measurements were acquired after conducting careful clinical examination. …”
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The Effect of Tracheal Intubation-Induced Autonomic Response on Photoplethysmography by Pekka Talke

“…Methods. 15 surgical patients having general anesthesia were enrolled into this clinical study. PPG was recorded electronically from a pulse oximeter. …”
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Mylohyoid Nerve Injection for Unsuccessful Anesthesia of Posterior Teeth with Successful Inferior Alveolar Nerve Block. by Rozh M Hussein

“…This study aimed to evaluate the impact of mylohyoid nerve variation on the persistence of pain following a successful inferior alveolar nerve block. Method: This clinical study was performed at the oral and maxillofacial department/college of Dentistry, Hawler Medical University. …”
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Efficacy of acupuncture in treating chemotherapy-related cognitive impairment in breast cancer patients: A systematic review and meta-analysis protocol. by Lishi Liu, Zihan Meng, Jun Yan

“…From the time of database construction to October 2024, we will search seven literature databases, three clinical study registry databases, and three sources of gray literature. …”
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Probing the Clinical, Laboratory, and Sociodemographic Factors Associated with Malaria: A Case-Control Study by Ritesh Upadhyay, Annasaheb J. Dhumale, Chanchlesh Dehariya, Renu Waghmare, Amit Rangari

“…Methods: This retrospective record-based clinical study subjects with malaria were further divided into P. vivax and P. falciparum cases. …”
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Therapeutic Benefit of Dillenia indica in Diabetes and Its Associated Complications by Parul Kamboj, Narayan C. Talukdar, Sanjay K. Banerjee

“…In spite of its wide use in the Northeast region of India as traditional medicine, there is only one clinical study where the antidiabetic potential of the fruit powder has been shown. …”
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Results of Femtosecond Laser-Assisted Descemet Stripping Automated Endothelial Keratoplasty by Mohamed H. Hosny, Ayah Marrie, M. Karim Sidky, Sherif GamalEldin, Mohsen Salem

“…A retrospective observational clinical study. Methods. 20 eyes with SBK and Fuchs’ dystrophy underwent a Femto-assisted DSAEK by laser cutting of two matching posterior stromal discs in the recipient and donor corneas and then fitting the donor disc in the posterior corneal defect of the recipient using Busin’s glide or Terry forceps. …”
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Long-Term Changes in Sarcopenia and Body Composition in Diabetes Patients with and without Charcot Osteoarthropathy by Michael Zaucha Sørensen, Rasmus Bo Jansen, Tomas Møller Christensen, Per E. Holstein, Ole Lander Svendsen

“…Prospective observational clinical study. Twenty-one subjects were included and had two DXA scans done with mean 8.6-year intervals to compare changes in lean mass and fat distribution. …”
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Comparative Analysis of CBCT vs Intraoral Radiography for Interproximal Caries Detection: A Prospective Diagnostic Study by S. Ganesan, Kavitha Ramachandran, Nagaland Tirupati, Arishah Gulzar, H. Cyril Benedict, P. Sai Archana

“…Objective: This prospective clinical study aimed to compare the diagnostic accuracy of CBCT and intraoral radiography in detecting interproximal caries. …”
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Prediction of success in assisted reproductive technology with the help of morphology of the testis by N. G. Kulchenko

“…To evaluate the morphological changes of spermatogenic epithelium in patients with male infertility in terms of prognosis of ART success.Patients and methods. 264 men with infertility were examined. The scope of clinical study of all patients included: history, examination, determination of blood hormones, study of ejaculate, karyotype, ultrasound. …”
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Physiological Stimulation of the Synthesis of Preelastic Fibers in the Dermis of a Patient with Fibrosis by Jose Maria Pereira de Godoy, Lívia Maria Pereira de Godoy, Maria de Fatima Guerreiro Godoy, Dalisio de Santi Neto

“…The aim of the present study was to report the physiological stimulation of the synthesis of preelastic fibers in the dermis of a patient with fibrosis. Design. A clinical study was conducted involving the analysis of histological changes in preelastic fibers following treatment for stage II primary lymphedema for the clinical reversal of lymphedema and fibrosis. …”
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