Outcome of Concurrent Occult Hemothorax and Pneumothorax in Trauma Patients Who Required Assisted Ventilation by Ismail Mahmood, Zainab Tawfeek, Ayman El-Menyar, Ahmad Zarour, Ibrahim Afifi, Suresh Kumar, Ruben Peralta, Rifat Latifi, Hassan Al-Thani

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Predicted quality benefits of achievable performance benchmarks of chronic heart failure care in China: results from a nationwide observational study by Xi Li, Chao Wang, Jingkun Li, Yupeng Wang, Xiaoqiang Bao, Meina Liu, Qiuju Zhang, Chang Yin, Xudong Ma

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Development of a nomogram for predicting early visual acuity outcomes and reoperation rate in patients with open globe injury by Luqian Yang, Shuming Ji, Yan Zhao, Yue Song, Xueni Liu, Hongpei Ji

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Risk of Subclinical Hypothyroidism in Breast Cancer Patients Treated With CT-Guided Radiation Therapy: A Prospective Observational Study by Amdisen L, Brink C, Lorenzen EL, Roenlev JD, Ewertz M, Cronin-Fenton D

“…Lau Amdisen,1 Carsten Brink,2,3 Ebbe Laugaard Lorenzen,2,3 Jeanette Dupont Roenlev,4 Marianne Ewertz,2 Deirdre Cronin-Fenton1 1Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark; 2Department of Clinical Research, University of Southern Denmark, Odense, Denmark; 3Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Odense, Denmark; 4Department of Oncology, Odense University Hospital, Odense, DenmarkCorrespondence: Lau Amdisen, Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Olof Palmes Allé 43-45, Aarhus N, 8200, Denmark, Tel +45 8716 8229, Email amdisen@clin.au.dkPurpose: The thyroid gland is an organ at risk in breast cancer survivors who receive radiation therapy to the supraclavicular lymph nodes. …”
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Exploring the relationship between mental health status and life events in children and adolescents: the role of mediating factors by Jiemei Xie, Jiemei Xie, Guoqiang Cheng, Mingliang Zhou, Qisheng Liang, Qianjin Wang, Qianjin Wang, Qianjin Wang

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Gestational Diabetes and Thyroid Autoimmunity by Ester Vitacolonna, Annunziata Lapolla, Barbara Di Nenno, Annalisa Passante, Ines Bucci, Cesidio Giuliani, Dominique Cerrone, Fabio Capani, Fabrizio Monaco, Giorgio Napolitano

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The increasing burden of group B Streptococcus from 2013 to 2023: a retrospective cohort study in Beijing, China by Yingxing Li, Wenhang Yang, Yi Li, Kexin Hua, Ying Zhao, Taie Wang, Lingli Liu, Yali Liu, Yao Wang, Wenjing Liu, Li Zhang, Renyuan Zhu, Shuying Yu, Hongli Sun, Hongtao Dou, Qiwen Yang, Yingchun Xu, Lina Guo

“…This study provides new data and insights for clinical research on GBS.…”
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A Review of the Therapeutic Potential of Ginseng and Its Bioactive Components in Nonalcoholic Fatty Liver Disease by Hao L, Li S, Li C, Zhang Z, Hu X, Yan H

“…Liyuan Hao,1,2,* Shenghao Li,1– 3,* Caige Li,4 Zhiqin Zhang,5 Xiaoyu Hu,2 Huimin Yan3 1School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 2Department of Infectious Diseases, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 3Clinical Research Center, Shijiazhuang Fifth Hospital, Shijiazhuang, Hebei, People’s Republic of China; 4Department of Endocrinology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China; 5College of Integrated Traditional Chinese and Western Medicine, Hebei University of Traditional Chinese Medicine, Shijiazhuang, Hebei, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaoyu Hu; Huimin Yan, Email xiaoyuhu202206@163.com; yanhm2538@163.comAbstract: Non-alcoholic fatty liver disease (NAFLD) is the major cause of chronic liver disease worldwide, with no universally recognized effective treatments currently available. …”
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Contrastive learning with transformer for adverse endpoint prediction in patients on DAPT post-coronary stent implantation by Fang Li, Zenan Sun, Ahmed abdelhameed, Tiehang Duan, Laila Rasmy, Xinyue Hu, Jianping He, Yifang Dang, Jingna Feng, Jianfu Li, Yichen Wang, Tianchen Lyu, Naomi Braun, Si Pham, Michael Gharacholou, DeLisa Fairweather, Degui Zhi, Jiang Bian, Cui Tao

“…This study introduces a new contrastive learning-based approach to enhance prediction efficacy over multiple time intervals.MethodsWe utilized retrospective, real-world data from the OneFlorida + Clinical Research Consortium. Our study focused on two primary endpoints: ischemic and bleeding events, with prediction windows of 1, 2, 3, 6, and 12 months post-DES implantation. …”
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Application of organoids in drug screening of gynecological malignant tumors by JIANG Yuanyuan, WEI Wenfei, WU Jingya, LI Huawen

“…To achieve individualized and precise treatment for gynecologic malignant tumors, there is an urgent need to develop in vitro models that closely resemble human tumors for clinical research. Drug screening is a technique used to identify and evaluate compounds with pharmacological activity and potential therapeutic effects, providing doctors with scientific guidance on drug use, thereby avoiding blind drug testing and reducing patients' therapeutic pain and economic burden by assessing the effects of different drugs under specific conditions. …”
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An Injectable Hydrogel Bioimplant Loaded with Engineered Exosomes and Triple Anti-Tuberculosis Drugs with Potential for Treating Bone and Joint Tuberculosis by Huang J, Li H, Mei Y, Yi P, Ren Y, Wang Y, Han L, Tang Q, Liu D, Chen W, An Y, Hu C

“…Jiayan Huang,1,* Han Li,2,* Yuting Mei,1 Pengcheng Yi,1 Yunyao Ren,1 Yunjuan Wang,3 Limei Han,1 Qiusha Tang,3 Dongfang Liu,3 Wei Chen,4 Yanli An,5 Chunmei Hu1 1Department of Tuberculosis, the Second Hospital of Nanjing, Affiliated to Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 2Department of Pharmacy, Central Hospital of Guangdong Provincial Nongken, Zhanjiang, Guangdong, People’s Republic of China; 3Medical School of Southeast University, Nanjing, People’s Republic of China; 4Department of Clinical Research Center, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 5Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging & Interventional Radiology (Southeast University), Center of Interventional Radiology & Vascular Surgery, Department of Radiology, Medical School, Zhong da Hospital, Southeast University, Nanjing, Jiangsu People’s Republic of China*These authors contributed equally to this workCorrespondence: Chunmei Hu, Department of Tuberculosis, the Second Hospital of Nanjing, Affiliated to Nanjing University of Chinese Medicine, Zhongfu Road 1-1, Yijiangmen Street, Nanjing, Jiangsu Province, 210009, People’s Republic of China, Email njyy003@njucm.edu.cnPurpose: Treatment for bone and joint tuberculosis (BJTB) is challenging due to its refractory and recurrent nature. …”
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Development and Evaluation of a Mindfulness-Based Mobile Intervention for Perinatal Mental Health: Randomized Controlled Trial by Sehwan Park, Hee Young Cho, Jin Young Park, Kyungmi Chung, Kyungun Jhung

“…Trial RegistrationClinical Research Information Service KCT0007166; https://tinyurl.com/458vfc4r…”
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Preliminary Assessment of Reference Region Quantification and Reduced Scanning Times for [18F]SynVesT-1 PET in Parkinson’s Disease by Kelly Smart, Carme Uribe, Kimberly L. Desmond, Sarah L. Martin, Neil Vasdev, Antonio P. Strafella

“…If further validated, these simplified procedures for [18F]SynVesT-1 PET quantification can facilitate its application as a clinical research imaging technology and allow for larger study samples and include a broader scope of patients including those with neurodegenerative diseases.…”
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CHRONOTYPE AND DAILY FUNCTIONING OF PATIENTS WITH DIFFERENT MOTOR SUBTYPES OF PARKINSON DISEASE by A.D. Shkodina, M. Bardhan, K.A. Tarianyk, M. Yu. Delva

“…Methods and materials. We conducted clinical research on the basis of the Centre for Parkinson Disease and Neurodegenerative Diseases of the Department of Neurological Diseases of Poltava State Medical University. …”
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Research Progress on Neural Processing of Hand and Forearm Tactile Sensation: A Review Based on fMRI Research by Chen H, Fu S, Zhi X, Wang Y, Liu F, Li Y, Ren F, Zhang J, Ren L, Wang Y

“…Hao Chen,1,* Shifang Fu,2,* Xiaoyu Zhi,2 Yu Wang,2 Fanqi Liu,2 Yuetong Li,2 Fengjiao Ren,2 Junfeng Zhang,1,3,4 Longsheng Ren,1 Yanguo Wang2 1Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, People’s Republic of China; 2Rehabilitation Department, Tianjin University of Traditional Chinese Medicine Second Affiliated Hospital, Tianjin, 300250, People’s Republic of China; 3Rehabilitation Center, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, People’s Republic of China; 4National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, 300381, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yanguo Wang, Tianjin University of Traditional Chinese Medicine Second Affiliated Hospital, Tianjin, 300250, People’s Republic of China, Email tjwangyanguo@163.comAbstract: Tactile perception is one of the important ways through which humans interact with the external environment. …”
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Global and China trends and forecasts of disease burden for female lung Cancer from 1990 to 2021: a study based on the global burden of disease 2021 database by Bilu Li, Yuyan Wu, Yanhong Zhang, Chengyun Hu, Xue Li, Shanshan Luo, Chenyu Sun, Iyad Yousef, Yefei Wang, Chaoliang Tang

“…The aim is to provide a reliable theoretical basis and reference value for clinical research and practice in female lung cancer and offer guidance for resource allocation and policy-making in society. …”
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Pilot study of a ketogenic diet in bipolar disorder: a process evaluation by Benjamin P. Rigby, Nicole Needham, Helen Grossi, Ivana Kamenska, Iain H. Campbell, Ben Meadowcroft, Frances Creasy, Cheryl Fisher, Pankaj Bahuguna, John Norrie, Gerard Thompson, Melissa C. Gibbs, Maja Mitchell-Grigorjeva, Ailsa McLellan, Tessa Moses, Karl Burgess, Rachel Brown, Michael J. Thrippleton, Harry Campbell, Daniel J. Smith, Sharon A. Simpson

“…Future trials may benefit from increased clinical research capacity, better-defined entry and exit routes, additional interpersonal support, and greater understanding of how social and societal factors impact participation. …”
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Contribution of Open Access Databases to Intensive Care Medicine Research: Scoping Review by Julien Kallout, Antoine Lamer, Julien Grosjean, Gaétan Kerdelhué, Guillaume Bouzillé, Thomas Clavier, Benjamin Popoff

“…ConclusionsThe abundance of scientific outputs resulting from these databases, coupled with the diversity of topics addressed, highlight the importance of these databases as valuable resources for clinical research. This suggests their potential impact on clinical practice within intensive care settings. …”
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Ivermectin as a promising therapeutic option for onchocerciasis‐associated epilepsy by Mohammad Amin Manavi, Razieh Mohammad Jafari, Hamed Shafaroodi, Mohammad Sharifzadeh, Ahmad Reza Dehpour

“…About one third of Ugandan patients saw reduced seizure frequency or intensity after one 150 μg/kg dose. Clinical research in the Congo among infected epileptics on anti‐seizure medications (ASMs) suggested ivermectin may decrease seizure frequency following oral administration of ivermectin tablets (3 mg). …”
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Business Venturing in Regulated Markets—Taxonomy and Archetypes of Digital Health Business Models in the European Union: Mixed Methods Descriptive and Exploratory Study by Sascha Noel Weimar, Rahel Sophie Martjan, Orestis Terzidis

“…In addition, 6 archetypes of DHT business models were identified: administration and communication supporter (A1), insurer-to-consumer digital therapeutics and care (A2), diagnostic and treatment enabler (A3), professional monitoring platforms (A4), clinical research and solution accelerators (A5), and direct-to-consumer wellness and lifestyle (A6). …”
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