Overcoming immune evasion with innovative multi-target approaches for glioblastoma by Hai Su, Yin Peng, Yilong Wu, Xiaoli Zeng, Xiaoli Zeng, Xiaoli Zeng

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SARS-CoV-2 and Subacute Thyroiditis: A Case Report and Literature Review by Amir Mohammad Salehi, Hossain Salehi, Hossein Ali Mohammadi, Jamileh Afsar

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Oncolytic immunotherapy: multiple mechanisms of oncolytic peptides to confer anticancer immunity by Xing Huang, Tingbo Liang, Tianyu Tang, Gang Zhang

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The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 I... by Geir Hetland, Egil Johnson, Torstein Lyberg, Gunnar Kvalheim

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Letter to Editor: a giant peritoneal loose body in the pelvic cavity by Ke Wu, Qiu-Ling Wang, Wei Ren, Wu-Bin Guo

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Overview of oral soft tissue esthetic assessment methods based on smile esthetics by XU Yangeng, ZHANG Yanling, HU Wenjie, WANG Cui, WEI Ning

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KLF4: a multifunctional nexus connecting tumor progression and immune regulation by Yunjie Ju, Wen Xiao, Bryan James Mathis, Ying Shi

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Fetal Safety in MRI During Pregnancy: A Comprehensive Review by Gal Puris, Angela Chetrit, Eldad Katorza

“…Regarding gadolinium-based contrast agents, the evidence is conflicting: while some studies suggest risks such as stillbirth and rheumatological conditions, animal studies show minimal fetal retention and no significant toxicity, and later clinical research has not substantiated these risks. The existing literature on fetal MRI is encouraging, suggesting minimal risks; however, further investigation through larger, prospective and long-term follow-up studies is essential to comprehensively determine its safety and late effects.…”
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Clinical observation of VR virtual reality rehabilitation training combined with acupuncture in the treatment of mild cognitive impairment by Ying Fu, Hui Wang

“…This directly affects the patient's motor function, daily living ability, and social adaptability, and brings many difficulties to the patient's reintegration into society. Therefore, clinical research on MCI is very necessary. The purpose of this paper is to study the efficacy of acupuncture and moxibustion in the treatment of MCI based on VR virtual reality technology. …”
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Efficacy of linaclotide in combination with polyethylene glycol for bowel preparation in Chinese patients undergoing colonoscopy polypectomy: protocol for a randomised controlled t... by Jing Xu, Ping-ping Chen, Dong Chen, Hui-Ying Zhao, Xiao-Feng Cai, Xiao-Bin Wang, Chao-Xu Liu

“…Secondary outcomes include evaluating the tolerability and safety of the bowel preparation regimens, bowel diary assessments, postpolypectomy complications (such as bleeding and perforation) and the size and number of removed polyps.Ethics and dissemination The study has received approval from the Clinical Research Ethics Committee of The First Affiliated Hospital, Zhejiang University School of Medicine. …”
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Intratumoral <i>Fusobacterium nucleatum</i> in Pancreatic Cancer: Current and Future Perspectives by Domenica Lucia D’Antonio, Anna Zenoniani, Samia Umme, Adriano Piattelli, Maria Cristina Curia

“…Furthermore, this review underscores the clinical research significance of <i>Fn</i> as a potential tumor biomarker and therapeutic target, offering a novel outlook on its applicability in cancer detection and prognostic assessment. …”
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Advancements related to probiotics for preventing and treating recurrent respiratory tract infections in children by Yali Zhang, Yali Zhang, Yingying Xu, Yingying Xu, Ling Hu, Ling Hu, Xiaomei Wang

“…Probiotics have recently emerged as promising agents for modulating intestinal microecology and have gained considerable attention in clinical research on preventing and treating RRTIs in children. …”
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Robust Automated Harmonization of Heterogeneous Data Through Ensemble Machine Learning: Algorithm Development and Validation Study by Doris Yang, Doudou Zhou, Steven Cai, Ziming Gan, Michael Pencina, Paul Avillach, Tianxi Cai, Chuan Hong

“… Abstract BackgroundCohort studies contain rich clinical data across large and diverse patient populations and are a common source of observational data for clinical research. Because large scale cohort studies are both time and resource intensive, one alternative is to harmonize data from existing cohorts through multicohort studies. …”
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Re-analysis of the current status of clinical trial registration in China by Shuwen Li, Shuwen Li, Jianhao Li, Wenjing Zeng, Zhicheng Li, Jietong Zhang, Siying Wang, Nenggui Xu, Zeli Li, Zeli Li

“…The sources of clinical trial registration platforms analyzed in the literature were divided into three categories: single platform, dual platform, and multiple platforms.ConclusionChiCTR plays a key role in enhancing transparency in clinical research, promoting standardization and normalization of research, strengthening domestic and international scientific research cooperation, and advancing medical innovation and public health improvement. …”
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Understanding patient views and experiences of the IDENTIfication of PALLiative care needs (IDENTI-Pall): a qualitative interview study protocol by Sarah Mitchell, Isabel Leach, Nicola Turner, C R Mayland

“…Other activities include the development of patient-centred outcomes for clinical practice and policy in relation to the use of palliative care identification tools.Trial registration number National Institute for Health Research (NIHR) Clinical Studies Portfolio, UK Clinical Research Network (UKCRN) Study number 51296.…”
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替奈普酶治疗急性缺血性卒中的研究进展及展望 Research Progress and Prospect of Tenecteplase in the Treatment of Acute Ischemic Stroke by 徐露，董漪，董强 (XU Lu, DONG Yi, DONG Qiang)

“…Abstract: This paper summarizes the clinical research results of tenecteplase in the treatment of acute ischemic stroke and looks forward to the broader clinical application and demand of tenecteplase. …”
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Treating Facial Scars using Polydioxanone Threads by Mohammad Khaled Hamolaila, Mazen Zenati, Asaad Shehada

“…Polydioxanone (PDO) threads offer a minimally invasive and cost-effective solution that enhances collagen production and skin texture.This study aimed to evaluate the effectiveness of PDO threads in the management of atrophic facial scars due to the lack of clinical research on this topic.A prospective clinical study was conducted on 20 patients with facial atrophic scars caused by accidents or previous surgical procedures. …”
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Validation of the Japanese Version of the Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s Disease-Rating Scale (QUIP-RS) by Maiko Takahashi, Jinsoo Koh, Shoko Yorozu, Yoshinori Kajimoto, Yoshiaki Nakayama, Mayumi Sakata, Masaaki Yasui, Yasuhiro Hiwatani, Daniel Weintraub, Hidefumi Ito

“…Use of QUIP-RS-J enables standardized assessment of ICBs and can be used in clinical research, including international multicenter studies.…”
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Optimal Timing and Treatment Modalities of Arytenoid Dislocation and Subluxation: A Meta-Analysis by Andrea Frosolini, Valeria Caragli, Giulio Badin, Leonardo Franz, Patrizia Bartolotta, Andrea Lovato, Luca Vedovelli, Elisabetta Genovese, Cosimo de Filippis, Gino Marioni

“…The findings highlight the importance of TT, suggesting that early intervention is paramount. Future clinical research is needed to further refine these findings and optimize treatment protocols.…”
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Quantitative Analysis of Multicomponents in Qufeng Zhitong Capsule and Application of Network Pharmacology to Explore the Anti-Inflammatory Activity of Focused Compounds by Mengjie Xue, Yuting Zhao, Ying Cui, Jing Yang, Yuefei Wang, Xin Chai

“…The potential value of this study could not only support a quality evaluation of QZC but also provide a theoretical basis for further in-depth research of QZC in clinical research.…”
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