Ambulatory Endoscopy – Perspectives from the Community by Iain Murray, Naoki Chiba, Paul Adams

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Association between the ABCC11 gene polymorphism-determined earwax properties and external auditory canal microbiota in healthy adults by Yasunobu Amari, Masahiro Hosonuma, Takuya Mizukami, Junya Isobe, Yuki Azetsu, Eiji Funayama, Yuki Maruyama, Toshiaki Tsurui, Kohei Tajima, Aya Sasaki, Yoshitaka Yamazaki, Ryota Nakano, Yutaka Sano, Atsushi Ishida, Tatsuya Nakanishi, Seiji Mochizuki, Yuri Yoshizawa, Sumito Kumagai, Sakiko Yasuhara, Kakei Ryu, Tatsunori Oguchi, Atsuo Kuramasu, Kiyoshi Yoshimura, Takehiko Sambe, Sei Kobayashi, Naoki Uchida

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Osteopenia Metabolomic Biomarkers for Early Warning of Osteoporosis by Jie Wang, Dandan Yan, Suna Wang, Aihua Zhao, Xuhong Hou, Xiaojiao Zheng, Jingyi Guo, Li Shen, Yuqian Bao, Wei Jia, Xiangtian Yu, Cheng Hu, Zhenlin Zhang

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Editorial: Women in renal pharmacology 2023 by Nuria Lloberas, Laure Elens, Brenda de winter

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Blowhole Colostomy for Clostridium difficile-Associated Toxic Megacolon by Jeroen Kerstens, Ian Diebels, Charles de Gheldere, Patrick Vanclooster

“…Although prospective clinical research regarding the surgical management of TM is lacking, decompressive procedures like blowhole colostomy are reported to carry a high risk of postoperative morbidity and mortality and are widely regarded as obsolete. …”
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Contemporary treatment of right ventricular failure by Bibhuti B. Das, MD, Shashi Raj, MD, FAAP, FACC

“…Therapeutic strategies are limited for RVF, as basic and clinical research has historically focused mainly on the left ventricle. …”
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EVALUATION OF THE THERAPEUTIC EFFECTS OF SALVIA ROSMARINUS ESSENTIAL OIL ON NERVOUS SYSTEM DISORDERS by Malina Mihaela Visternicu, Viorica Rarinca, Vasile Burlui, Alin Ciobica

“…Preclinical and clinical research suggests that rosemary extracts, through their active compounds, may enhance cognitive function, protect neurons from oxidative stress, and modulate neurotransmitters involved in cognitive and emotional processes. …”
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Mushroom β-glucan and polyphenol formulations as natural immunity boosters and balancers: nature of the application by Maja Kozarski, Anita Klaus, Leo van Griensven, Dragica Jakovljevic, Nina Todorovic, Wan Abd Al Qadr Imad Wan-Mohtar, Jovana Vunduk

“…The literature data on their bioavailability, metabolic transformations, preclinical and human clinical research, and safety are discussed. Immunomodulatory mechanisms of polyphenol ingredients are also considered. …”
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Effects of Type 2 Diabetic Serum on Proliferation and Osteogenic Differentiation of Mesenchymal Stem Cells by Xiangqun Deng, Min Xu, Moyu Shen, Jinluo Cheng

“…Our data demonstrate the importance of stratifying the study population according to glycemic control in clinical research into diabetic osteoporosis.…”
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Effect of Combined Antihypertensive and Lipid-Lowering Therapies on Cognitive Function: A New Treatment Strategy? by Ze-Min Kuang

“…To provide a reference for clinical treatment, we analyzed the potential mechanisms of cognitive dysfunction induced by hypertension and hyperlipidemia, the clinical research and controversy of antihypertensive and lipid-lowering therapies on cognitive function, and the clinical value of combined antihypertensive and lipid-lowering therapy. …”
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The data-intensive research paradigm: challenges and responses in clinical professional graduate education by Chunhong Yang, Yijing Chen, Changshun Qian, Fangmin Shi, Fangmin Shi, You Guo, You Guo, You Guo, You Guo, You Guo

“…With the widespread application of big data, artificial intelligence, and machine learning technologies in the medical field, a new paradigm of data-intensive clinical research is emerging as a key force driving medical advancement. …”
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Coronavirus Anxiety Scale: A New Instrument to Measure Anxiety Symptoms Associated with COVID-19 by Juan Aníbal González-Rivera, Adam Rosario-Rodríguez, Andrés Cruz-Santos

“…Conclusions: These results support the scale as a useful and valid tool for clinical research and practice.…”
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Research Progress on Alleviatory Effects of 6-Gingerol and 6-Shogaol on Intestine Tight Junction Damage by LI Yu, OUYANG Fangxin, ZHANG He, WANG Wenyu, DONG Jingxiao, LI Dapeng, LI Feng

“…Through comprehensive analysis of clinical research and experimental results in recent years, it is found that 6-gingerol and 6-shogaol can improve the expression levels of tight junction-related proteins and maintain the integrity and biofunction of the intestinal barrier by inhibiting inflammation, oxidative stress and apoptosis as well as regulating the composition of intestinal microbiota. …”
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Arterial Spin Labeling (ASL) fMRI: Advantages, Theoretical Constrains and Experimental Challenges in Neurosciences by Ajna Borogovac, Iris Asllani

“…In this review, we start by highlighting theoretical complexities and technical challenges of ASL fMRI for basic and clinical research. While underscoring the main advantages of ASL versus other techniques such as BOLD, we also expound on inherent challenges and confounds in ASL perfusion imaging. …”
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Importance of Human Faecal Biobanking: From Collection to Storage by Lewandowska Izabela, Grzech Katarzyna, Krzysztoń-Russjan Jolanta

“…The freezing and storage conditions of faecal samples in biobanks influence the preservation of the integrity and stability of genetic material and play a crucial role in scientific and clinical research quality. In recent years, there has been a particular increase in the number of studies related to the gut microbiome and the importance of its impact on the functioning human body. …”
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Auditing Clinical Outcomes after Introducing Off-Licence Prescribing of Atypical Antipsychotic Melperone for Patients with Treatment Refractory Schizophrenia by Frank Röhricht, Seema Gadhia, Rinku Alam, Melissa Willis

“…The example of a small group of patients responding well to a comparably safe and inexpensive atypical antipsychotic with favourable side effect profile should encourage clinicians to use this tool as third-line treatment and to conduct more systematic clinical research.…”
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Failure in Asthma Control: Reasons and Consequences by Fulvio Braido

“…Clinical research showed that asthma control is an achievable target. …”
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Topical Application of Liriope platyphylla Extract Attenuates Dry Eye Syndrome Induced by Particulate Matter by Su Jeong Song, Soo-Wang Hyun, Tae Gu Lee, Bongkyun Park, Kyuhyung Jo, Ik Soo Lee, Chan-Sik Kim

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SARS-CoV-2 Viral Shedding and Associated Factors among COVID-19 Inpatients and Outpatients by Masoomeh Sofian, Behzad Khansarinejad, Ehsanollah Ghaznavi-Rad, Farzaneh Shokoohi, Hossein Mazaherpour, Farzane Farmani, Mona Sadat Larijani, Leila Pakpour, Amitis Ramezani

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Connectivity changes following transcranial alternating current stimulation at 5-Hz: an EEG study by Tien-Wen Lee, Gerald Tramontano

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