Causal Association Between Obstructive Sleep Apnea and Migraine: A Bidirectional Mendelian Randomization Study by Wang YP, Wei HX, Hu YY, Zhang C, Niu YM

“…Yu-Pei Wang,1,* Hui-Xia Wei,2,* Yuan-Yuan Hu,3 Chao Zhang,4 Yu-Ming Niu3– 5 1Department of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, People’s Republic of China; 2Department of Anesthesiology, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, People’s Republic of China; 3Department of Stomatology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, People’s Republic of China; 4Center for Evidence-Based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, People’s Republic of China; 5Hubei Key Laboratory of Embryonic Stem Cell Research, Hubei Provincial Clinical Research Center for Umbilical Cord Blood Hematopoietic Stem Cells, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yu-Ming Niu, Department of Stomatology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, People’s Republic of China, Tel +86 13581370999, Email niuyuming@yeah.net Chao Zhang, Center for Evidence-Based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, People’s Republic of China, Email zhangchao0803@126.comObjective: Patients with obstructive sleep apnea (OSA) frequently suffer from migraine, however the causal relationship between OSA and migraine is unknown. …”
Get full text

Correlation Between the Ratio of Uric Acid to High-Density Lipoprotein Cholesterol (UHR) and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus:A Cross-Sectional Study by Wang L, Liu L, Luo H, Wu Y, Zhu L

“…Leran Wang,1 Lei Liu,2 Huilan Luo,3– 5 Yiling Wu,3– 5 Lingyan Zhu3– 5 1Queen Mary School, Jiangxi Medical College, Nanchang University, Nanchang City, People’s Republic of China; 2Department of Endocrinology, Lu’an Hospital of Anhui Medical University, Lu’an City, Anhui Province, People’s Republic of China; 3Department of Endocrinology and Metabolism, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang City, People’s Republic of China; 4Jiangxi Clinical Research Center for Endocrine and Metabolic Disease, the First Affiliated Hospital of Nanchang University, Nanchang City, People’s Republic of China; 5Jiangxi Branch of National Clinical Research Center for Metabolic Disease, Nanchang City, People’s Republic of ChinaCorrespondence: Lingyan Zhu, Jiangxi Branch of National Clinical Research Center for Metabolic Disease, No. 17, Yongwaizheng Street, Nanchang City, Jiangxi Province, People’s Republic of China, Tel +86-13870690788, Email zly982387@126.comBackground/Objective: Considering the uncertain relationship between high-density lipoprotein cholesterol (HDL-C) and uric acid (UA) with diabetic retinopathy (DR),this study investigates the link between Uric Acid to High-Density Lipoprotein Cholesterol (UHR) and DR in T2DM patients, evaluating its potential for DR diagnosis and early prediction.Study Design and Data Collection: This retrospective study analyzed 1450 type 2 diabetes patients, divided into NDR and DR groups by retinal exams. …”
Get full text

Efficacy of a simple intravitreal perfluoropropane injection in treating unclosed idiopathic macular holes following vitrectomy by Zexia Dou, Jindong Han, Shaozhen Zhao

Get full text

Phase 1 study of novel anti-platelet agent to overcome pharmacogenomic limitations of clopidogrel by Anil Pareek, Nitin Chandurkar, Vivek Raut, Kumar Naidu

Get full text

Probiotics alleviate painful diabetic neuropathy by modulating the microbiota–gut–nerve axis in rats by Ye Jiang, Jing Yang, Min Wei, Jiayin Shou, Shixiong Shen, Zhuoying Yu, Zixian Zhang, Jie Cai, Yanhan Lyu, Dongsheng Yang, Yongzheng Han, Jinpiao Zhu, Zhigang Liu, Daqing Ma, Guo-gang Xing, Min Li

Get full text

Endogenous Estrogen Influences Predator Odor-Induced Impairment of Cognitive and Social Behaviors in Aromatase Gene Deficiency Mice by Yaner Gao, Lei Ma, Feng Gao, Zuoli Sun, Zhengrong Zhang, Yuhong Li, Rena Li

Get full text

The Association of a Genetic Variant in SCAF8-CNKSR3 with Diabetic Kidney Disease and Diabetic Retinopathy in a Chinese Population by Li Jin, Tao Wang, Song Jiang, Miao Chen, Rong Zhang, Cheng Hu, Weiping Jia, Zhihong Liu

Get full text

Associations of Salivary BPIFA1 Protein in Chronic Periodontitis Patients with Type 2 Diabetes Mellitus by Yue Guo, Lin-Na Guo, Jun-Fei Zhu, Chen-Yi Tang, Yun-Zhi Feng, Hou-De Zhou

Get full text

Comprehensive Analysis of Transcriptome Sequencing Data in the Lung Tissues of COPD Subjects by Woo Jin Kim, Jae Hyun Lim, Jae Seung Lee, Sang-Do Lee, Ju Han Kim, Yeon-Mok Oh

Get full text

Pilot Trial of the Reboot Online Program: An Internet-Delivered, Multidisciplinary Pain Management Program for Chronic Pain by Regina Schultz, Jessica Smith, Jill M. Newby, Tania Gardner, Christine T. Shiner, Gavin Andrews, Steven G. Faux

Get full text

The Impact of COVID-19 Outbreak on Nosocomial Infection Rate: A Case of Iran by Maryam Jabarpour, Mahlagha Dehghan, Giti Afsharipour, Elham Hajipour Abaee, Parvin Mangolian Shahrbabaki, Mehdi Ahmadinejad, Mahboobeh Maazallahi

Get full text

The relationship of platelet distribution width with all-cause and cardiovascular mortality in peritoneal dialysis patients by Chunyu Lu, Shuiqin Cheng, Wenjing Fan, Zhihong Zhang, Jinquan Wang

Get full text

3HP preventive treatment among children and adolescents with HIV and child household contacts of TB patients by A. Kinikar, R. Borse, B. Randive, P. Kamath, S.K. Mattoo, M. Parmar, H. Solanki, V. Mave, A. Gupta, R.E. Chaisson, N. Suryavanshi

Get full text

Downregulation of the Proinflammatory State of Circulating Mononuclear Cells by Short-Term Treatment with Pioglitazone in Patients with Type 2 Diabetes Mellitus and Coronary Artery... by Andreas Pfützner, Alexander Weise, Elisabeth Pfützner-Riehn, Georg Lübben, Michael Morcos, Efstrathios Karagiannis, Matthias Weber, Thomas Forst

Get full text

Health-related quality of life in patients with liver cirrhosis following adjunctive nurse-based care versus standard medical care: a pragmatic, multicentre, randomised controlled... by Anncarin Svanberg, Maria Hjorth, Daniel Sjöberg, Elenor Kaminsky, Fredrik Rorsman, Riccardo Lo Martire

Get full text

Electrochemical Skin Conductance as a Marker of Painful Oxaliplatin-Induced Peripheral Neuropathy by Jean-Baptiste Delmotte, Abdulkarim Tutakhail, Kahina Abdallah, Pauline Reach, Marguerite D’Ussel, Gael Deplanque, Hélène Beaussier, François Coudoré

Get full text

Exploring the Relationship between Perfectionism and Pain in Patients with Temporomandibular Disorders: A Cross-Sectional Study by Xin Xiong, Shi-Yong Zhang, Jing Zhang, Nan Jiang, Li-Ming Zhang, Hao-Lun Yang, Yuan Yue

Get full text

Dietary protein intake and PM2.5 on ovarian cancer survival: A prospective cohort study by He-Li Xu, Yi-Fan Wei, Qi Bao, Ya-Li Wang, Xiao-Ying Li, Dong-Hui Huang, Fang-Hua Liu, Yi-Zi Li, Yue-Yang Zhao, Xin-Xin Zhao, Qian Xiao, Song Gao, Ren-Jie Chen, Ling Ouyang, Xia Meng, Xue Qin, Ting-Ting Gong, Qi-Jun Wu

Get full text

Use of Patient-Reported Outcome Measures in Lower Extremity Research by Yongni Zhang, Yaning Zang, Jiayi Ren, Wenhao Guo, Ashley Disantis, Siyu Liu, RobRoy L Martin

“…The second search included clinical research articles that utilized a PROM. Case reports, reviews, and basic science articles were excluded…”
Get full text

Differences in technical and clinical perspectives on AI validation in cancer imaging: mind the gap! by Ioanna Chouvarda, Sara Colantonio, Ana S. C. Verde, Ana Jimenez-Pastor, Leonor Cerdá-Alberich, Yannick Metz, Lithin Zacharias, Shereen Nabhani-Gebara, Maciej Bobowicz, Gianna Tsakou, Karim Lekadir, Manolis Tsiknakis, Luis Martí-Bonmati, Nikolaos Papanikolaou

“…In cancer imaging AI research, clinical researchers prioritise explainability, while technical researchers focus on transparency and traceability, and see potential in synthetic datasets. …”
Get full text