Efficacy of sacituzumab govitecan versus treatment of physician’s choice in previously treated HR+ and HER2− mBC: a meta-analysis of TROPiCS-02 and EVER-132-002 trials by Oleg Gluz, Binghe Xu, Rita Nanda, Anandaroop Dasgupta, Ankita Kaushik, Wendy Verret, Akanksha Sharma, Barinder Singh, Hope S. Rugo

“…These findings extend previous research, supporting the integration of SG into clinical practice guidelines at a global level for treating the HR+/HER2− mBC population irrespective of status and duration of prior CDK4/6i exposure.…”
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Challenges in amphetamine medication availability for individuals with ADHD: a narrative review of the current state of evidence by Mansour M. Alotaibi, Mansour M. Alotaibi, Naif Z. Alrashdi, Naif Z. Alrashdi, Bakriah Alzubaidi, Marzouq K. Almutairi, Sultan A. Alanazi, Anwar B. Almutairi, Mohammed M. Alqahtani, Mohammed M. Alqahtani

“…Policy reports from national institutions highlight persistent barriers to AMPH access, despite their inclusion in recent clinical practice guidelines. Prescription trends suggest significant treatment gaps for AMPH stimulants.ConclusionThe available evidence suggests a likely shortfall in AMPH-based medications. in Saudi Arabia, despite global and local evidence supporting their efficacy. …”
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Horner syndrome as a complication of ultrasound-guided ablation therapy for thyroid nodules: a scoping review by Tianhao Xie, Tianhao Xie, Yan Fu, Xiaoshi Jin, Xiaoshi Jin, Xiangxiang Ren, Xiangxiang Ren, Jing Zhang, Jing Zhang, Qian Sun, Qian Sun

“…Future prospective studies are needed to clarify incidence rates, long-term prognosis, and refine clinical practice guidelines.…”
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Safety and tolerability of a bevacizumab biosimilar (Effivia®) in adult Mexican patients with cancer: a multicenter, observational, prospective clinical study by Alberto Alfonso Pimentel-Rentería, David Francisco Cantú de León, Eliseo Neftalí De la Cruz, David Suárez, Manuel Rodulfo Segura, José Gustavo Núñez, Livan Delgado-Roche

“…Treatment regimens followed the Clinical Practice Guidelines and the Investigator criteria.ResultsAdult patients (n = 82) were included, 65.8% (n = 54) completed the full 6-cycle treatment, while 34.1% (n = 28) meet the criteria for early discontinuation including disease progression (18.3%), voluntary withdrawal or dropout (7.3%), treatment availability or brand switching (4.9%), and serious adverse events (3.7%). …”
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A roadmap to increasing access to AQP4-Ig testing for NMOSD: expert recommendations by Raquel Vassão-Araujo, Samira Apóstolos, Angela Marie Jansen, Marco A. Lana-Peixoto, Antonio Pereira Gomes Neto, Mariana Rico-Restrepo, Soniza Vieira Alves-Leon, Douglas Kazutoshi Sato

“…The public healthcare system should ensure the availability and accessibility of AQP4-IgG antibody testing. Clinical practice guidelines for NMOSD diagnosis and treatment must be established. …”
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Summary of best evidence for safe management of vasopressors through peripheral intravenous catheters by Guanjie Chen, Chen Shen, Chenwei Pan, Xiaohui Gao, Mingzhu Sun, Xiaoqing Li

“…Literature types included clinical practice guidelines, clinical decisions, expert consensuses, systematic reviews, and evidence summaries. …”
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Rationale and Design of a Randomized Controlled Trial on Intensive Management of Blood PRESSure and Cholesterol in Elderly Chinese with Hypertension and Atrial FibrillatION (IMPRES... by Wei Zhang, Yi Chen, Qifang Huang, Ji-Guang Wang, Tianyu Xu, Xiaoxia Fu.

“…The procedures set out in this protocol are in accordance with the principles of the Declaration of Helsinki and Good Clinical Practice guidelines. The results will be published following the CONSORT statement in a peer-reviewed scientific journal (Trial registration number: NCT04111419).…”
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A Prospective Observational Study on Viral Conjunctivitis: An Exasperating Entity by Rupali Tyagi, Priyanka Gupta, Aeshvarya Dhawan

“…Aim: To analyse the clinical profile of viral conjunctivitis patients attending the Ophthalmic Outpatient Department (OPD) of a tertiary care hospital to appraise clinical practice guidelines. Materials and Methods: This was a prospective observational study conducted in a tertiary care hospital in the Department of Ophthalmology, Dehradun, Uttarakhand, India over a period of three months, from June 1, 2023, to August 31, 2023. …”
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Effect of music on clinical outcome after hip fracture operations (MCHOPIN): study protocol of a multicentre randomised controlled trial by Detlef van der Velde, Marten J Poley, Esther M M van Lieshout, Michael H J Verhofstad, Johan Haumann, Johannes Jeekel, Robert Haverlag, Victor X Fu, Leonie J P Slegers

“…The trial will be carried out following the Declaration of Helsinki principles, Good Clinical Practice guidelines and Dutch Medical Research Involving Human Subjects Act. …”
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Physician’s Adherence to Clinical Guidelines for in-Hospital Anticoagulant Prescribing by A. A. Chernov, E. V. Kleymenova, D. A. Sychev, L. P. Yashina, M. D. Nigmatkulova, V. A. Otdelenov, S. A. Payushchik

“…Their safety closely depends on physician’s compliance with clinical practice guidelines (CPG) and summary of product characteristics (SmPC).Aim. …”
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A CDE-based data structure for radiotherapeutic decision-making in breast cancer by Fabio Dennstädt, Maximilian Schmalfuss, Johannes Zink, Janna Hastings, Roberto Gaio, Max Schmerder, Nikola Cihoric, Paul Martin Putora

“…The framework was translated into machine-readable JavaScript Object Notation (JSON) format. Six clinical practice guidelines of the American Society for Radiation Oncology (ASTRO) were analyzed as full text to evaluate how many guideline recommendations and corresponding decision-making criteria could be represented using our framework. …”
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Impact of an intervention for osteoarthritis based on exercise and education on metabolic health: a register-based study using the SOAD cohort by Ola Rolfson, Martin Englund, Stefan Lohmander, Johanna Vinblad, Allan Abbott, Simone Battista, Filippo Recenti, Ali Kiadaliri, Thérése Jönsson, Andrea Dell’Isola

“…No essential differences were found in the total cholesterol levels.Conclusion An OA exercise and education intervention designed following OA clinical practice guidelines led to small and unlikely clinically relevant improvements in metabolic health markers in individuals with OA and diabetes.…”
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Key Gaps in the Prevention and Treatment of Obesity in Children and Adolescents: A Critical Appraisal of Clinical Guidelines by Francesca Filippi-Arriaga, Michael Georgoulis, Eirini Bathrellou, Meropi D. Kontogianni, Eduard Mogas, Graciela Gastelum, Andreea Ciudin

“…Background: The worldwide increase in the prevalence of childhood obesity necessitates effective prevention and treatment strategies. Clinical practice guidelines (CPGs) offer guidance, but significant heterogeneity or lack of practical application exists in their recommendations. …”
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Sequencing and Integration of Cervical Manual Therapy and Vestibulo-oculomotor Therapy for Concussion Symptoms: Retrospective Analysis by Christopher Kevin Wong, Lauren Ziaks, Samantha Vargas, Tessia DeMattos, Chelsea Brown

“…# Background After concussion many people have cervicogenic headache, visual dysfunction, and vestibular deficits that can be attributed to brain injury, cervical injury, or both. While clinical practice guidelines outline treatments to address the symptoms that arise from the multiple involved systems, no preferred treatment sequence for post-concussion syndrome has emerged…”
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MultifocAL COntact Lenses for Myopia (MALCOLM) control in Australian children: a study protocol for a double-blind, contralateral eye, non-inferiority, randomised controlled clinic... by Isabelle Jalbert, Nancy Briggs, Rebecca Dang, Alex Hui, Danny Kho, Mimi Vi, Pauline Kang

“…This trial started recruitment during the recent COVID-19 pandemic in January 2021.Ethics and dissemination Ethics approval has been obtained from the UNSW Human Research Ethics Committee (HC200052), and the study complies with the Declaration of Helsinki and the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use Good Clinical Practice guidelines. The results of this trial will be disseminated in peer-reviewed publications and conference presentations.Trial registration number ACTRN12620000159954, CTN-00 282–1 v2, NCT06887920.…”
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Impact of an educational physiotherapy-yoga intervention on perceived stress in women treated with brachytherapy for cervical cancer: a randomised controlled mixed study protocol (... by Marta Jarlier, Estelle Laboureur, Kerstin Faravel, Laetitia Meignant, Maguy Del Rio, Sylvain Demontoy, Mailys De-Meric-de-Bellefon, Marie Cantaloube, Estelle Guerdoux

“…Qualitative analyses based on semistructured interview surveys will be conducted to gather valuable information and analyse in depth patients’ experiences with the intervention and UBT.Ethics and dissemination This study was approved by the French ethics committee (Comité de Protection des Personnes Ouest V, reference number 2023-A01491-44) on 22 February 2024 and will be carried out in accordance with the good clinical practice guidelines and the Declaration of Helsinki. …”
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Evaluating the perspectives of ChatGPT and Gemini on glenohumeral osteoarthritis management by Michael Megafu, DO, MPH, Omar Guerrero, BS, Rafay Hasan, BS, Larry Hunt, MBA, Devri Langhelm, BS, Benning Le, MS, Xinning Li, MD, Robert Kelly, IV, MD, Robert L. Parisien, MD, Antonio Cusano, MD

“…This study sought to evaluate Chat Generative Pre-Trained Transformer (ChatGPT) and Gemini's capacity to make quality medical recommendations regarding glenohumeral osteoarthritis, weighing them against the recommendations established in the Evidence-Based Clinical Practice Guidelines (CPGs) of the American Academy of Orthopaedic Surgeons (AAOS). …”
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Large simple randomized controlled trials—from drugs to medical devices: lessons from recent experience by Sergio Buccheri, Stefan James, Marion Mafham, Martin Landray, Tom Melvin, Jonas Oldgren, Richard Bulbulia, Louise Bowman, Lotje Anna Hoogervorst, Perla J. Marang-van de Mheen, Peter Juni, Peter McCulloch, Alan G. Fraser

“…Well-designed studies robustly inform clinical practice guidelines and decision-making, but administrative obstacles have made it increasingly difficult to conduct informative RCTs. …”
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Dietary intakes and nutritional issues in inborn errors of immunity: a systematic review by Macey Freer, Rani Bhatia, Rani Bhatia, Kahn Preece, Kahn Preece, Kirrilly M. Pursey, Kirrilly M. Pursey, Kirrilly M. Pursey

“…This review reinforces the need for dietetic input in people with an IEI and the development evidence-based clinical practice guidelines for people with an IEI.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO, identifier CRD42023412365.…”
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Phase II single vs hypofractionated irradiation for timely access to partial breast radiotherapy (SHIFT-PB) by Robert Olson, Marjorie Cua, Quinn Matthews, Jordanna Laing, Dylan Narinesingh, Alan Nichol, Tanya Berrang, Theodora Koulis, Tania Karan, Nick Chng

“…Various dose fractionation schedules for PBI have been recommended in clinical practice guidelines. In British Columbia (BC), a dose of 26 Gy in 5 fractions has been adopted. …”
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