Voices from the clinic: a qualitative analysis of physiotherapy strategies in musculoskeletal care for knee osteoarthritis patients by Jennifer Nguyen, Justine M. Naylor, Sarah Dennis, Rebecca Livings, Kathryn Mills, Siobhan M. Schabrun, Jeanette M. Thom

“…However, little is known about the extent to which physiotherapists adhere to clinical practice guidelines. This study aimed to explore the perspectives and care patterns of physiotherapists in Sydney, Australia on their delivery of knee osteoarthritis care and how this aligns with the 2019 Osteoarthritis Research Society International (OARSI) guidelines. …”
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Prospective exploration of the effect of adiposity and associated microbial factors on healing and progression of diabetic foot ulcers in Tanzania: study protocol of a longitudinal... by Fredirick Mashili, Agricola Joachim, Mabulla Mchembe, Faraja Chiwanga, Agbor Ako, Zulfiqar Abbas

“…Enrolling 150 participants per group will have a minimum power of 80% to detect a 20% difference in cumulative incidence of complete ulcer healing (at the 5% level of statistical significance) between the normal and high adiposity groups.Ethical considerations and dissemination of results This study will be conducted in compliance with the independent institutional review boards (IRBs), informed consent guidelines, the declaration of Helsinki and International Conference on Harmonisation, Good Clinical Practice Guidelines. Ethical clearance has been granted by the Muhimbili University of Health and Allied Sciences ethical review board (MUHAS Ref. …”
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Protocol for a living systematic review for the management of concussion in adults by Mark Bayley, Diana Velikonja, Shawn Marshall, Alexander Lithopoulos, Dorothyann Curran, Lisa Fischer, Christopher Knee, Julia Lauzon, Margaret Nevison

“…We are including English peer-reviewed observational studies, trials, qualitative studies, systematic reviews and clinical practice guidelines related to diagnosis/assessment or treatment of adult concussion. …”
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NTNU intranasal naloxone trial (NINA-1) study protocol for a double-blind, double-dummy, non-inferiority randomised controlled trial comparing intranasal 1.4 mg to intramuscular 0.... by Arne Kristian Skulberg, Ida Tylleskär, Anne-Cathrine Braarud, Jostein Dale, Fridtjof Heyerdahl, Sindre Mellesmo, Morten Valberg, Ola Dale

“…It adheres to the Good Clinical Practice guidelines as set out by the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use.Informed consent will be sought through a differentiated model. …”
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Survey of Glaucoma Practice Patterns Among Members of The Philippine Glaucoma Society by Edgar Felipe U. Leuenberger, MD, DPBO, James Paul S. Gomez, MD, DPBO, Karlo Paolo L. Alejo, MD, DPBO, Robert Edward T. Ang, MD, DPBO, Maria Zita Zagala-Meriales, MD, DPBO, Pamela C. Allarey, MD, DPBO, Aldo Mar B. Cariaga, MD, DPBO, John Mark S. De Leon, MD, DPBO, Sammy L. Ang, MD, DPBO

“…Conclusion: This survey showed majority of the glaucoma practices of PGS members appear to adhere to the current clinical practice guidelines.…”
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From gaps to guidelines: a process for providing guidance to bridge evidence gaps by Olga Yaroslavtseva, Judith Gargaro, Eleni M. Patsakos, Aishwarya Nair, Robert Teasell, Mark T. Bayley

“…Abstract Background Despite the proliferation of clinical research that can be used to inform Clinical Practice Guidelines there remain many areas where the number and quality of research studies vary widely. …”
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A Cross-sectional Survey of Physicians to Understand Biomarker Testing and Treatment Patterns in Patients with Prostate Cancer in the USA, EU5, Japan, and China by Christian Gratzke, Himani Aggarwal, Jeri Kim, Holly Chaignaud, Sabine Oskar

“…Conclusions and clinical implications: Overall, testing rates increased following PARPi approval and updated clinical practice guidelines; yet, there was a wide variation in the proportions of patients with mCRPC recommended for testing, and perceived barriers to testing remain, suggesting unmet needs for patients and physicians. …”
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Predictors of lipoprotein(a) variability in clinical practice and their impact on cardiovascular risk by Hyung Joon Joo, Seung Gyu Yun, Jae Hyoung Park, Soon Jun Hong, Cheol Woong Yu, Seung Yong Shin, Eung Ju Kim

“…Integrating these findings into clinical practice guidelines has the potential to improve cardiovascular risk management at the population level, reduce healthcare disparities, and inform targeted public health interventions aimed at cardiovascular prevention.…”
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Prescribing lithium for the management of persons suffering from bipolar disorders: expert consensus based on a Delphi study by Gaia Sampogna, Isabella Berardelli, Umberto Albert, Giulio Perugi, Maurizio Pompili, Alfonso Tortorella, Mirko Manchia, Gabriele Sani, Andrea Fiorillo

“…Our findings should be used to develop clinical practice guidelines and reduce the discrepancy between international guidelines and ordinary care.…”
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Treatment Patterns of Patients With Pulmonary Hypertension: A Descriptive Study in Colombia by Manuel Machado‐Duque, Andrés Gaviria‐Mendoza, Luis Fernando Valladales‐Restrepo, Manuel Pacheco, Juan Sebastián Franco, María delRosario Forero, Rubiela Suarez, Oscar Peñuela, Jorge E. Machado‐Alba

“…However, current clinical practice guidelines recommend the use of combined therapy. …”
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Yangxinshi Tablets Versus Trimetazidine on Exercise Tolerance After Percutaneous Coronary Intervention: Rationale and Design of the Double-blind, Randomized HEARTRIP Trial by Yi Li, Jian Zhang, Hong Chen, Yi Zhang, Jing Li, Haichu Yu, Xiaoping Meng, Haitao Yuan, Lili Shao, Yaling Han

“…The procedures set out in this protocol are in accordance with the principles of the Declaration of Helsinki and the Good Clinical Practice guidelines. The results will be published following the guidelines of the CONSORT statement in a peer-reviewed scientific journal (Trial registration number: NCT03809273).…”
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Community and Social Context: An Important Social Determinant of Cardiovascular Disease by *Rahul Singh, *Zulqarnain Javed, Tamer Yahya, Javier Valero-Elizondo, Isaac Acquah, Adnan A. Hyder, Muhammad Haisum Maqsood, Zahir Amin, Sadeer Al-Kindi, Miguel Cainzos-Achirica, Khurram Nasir

“…Disease prevention frameworks and clinical practice guidelines in the United States (US) have traditionally ignored upstream social determinants of health (SDOH), which are critical for reducing disparities in cardiovascular disease (CVD)—the leading cause of death in the US. …”
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Outcomes of Percutaneous Ultrasound-guided Splenic Procedures: A Retrospective Observational Study from a Tertiary Care Centre in Southern India by Ruth Anna Stephen, Vinu Moses, George M Varghese, KB Santhosh Babu, Suchita Chase, Shyamkumar N Keshava

“…As per the Society of Interventional Radiology (SIR) Clinical Practice Guidelines classification, six patients (27.3%) had Category-A complications with small perisplenic haematomas, three patients (13.6%) had Category-B complications, 10 patients (45.5%) had Category-C complications and two patients (9.1%) had Category-D complications. …”
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Clinical and immunological characteristic of children with recurrent episodes of acute laryngotracheitis, acute respiratory infections, otorhinolaryngological deseases by A. G. Chuvirova, M. N. Yartsev

“…The treatment in according with pediatric clinical practice guidelines, consultations with a pediatrician, otorhinolaryngologist, allergologist were provided to all children.Twenty five children (subgroup I b) received bacterial lysate (OM-85, 4 courses in 3 years ) in complex treatment. …”
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Equitable and effective clinical guidance development and dissemination: trauma aims to lead the way by Deborah M Stein, Elliott R Haut, Eileen M Bulger, Vanessa P Ho, Andres M Rubiano, Ashley Farley, Lacey N LaGrone, Danielle J Wilson, Maria Michaels, Meghan B Lane-Fall, Michael A Person, Linda Reinhart

“…The Institute of Medicine and the National Academies of Science, Engineering and Medicine have called for learning health systems, with emphasis on clinical practice guidelines (CPGs) as a means of limiting preventable deaths. …”
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Trends in clinical encounters and management for infertility among women attending Australian general practice: a national longitudinal study using MedicineInsight, 2011 to 2021 by Alice R Rumbold, Michael Davies, Danielle Mazza, Jacqueline Boyle, Vivienne Moore, Renae C Fernandez, Luke E Grzeskowiak

“…These findings support the development of clinical practice guidelines to enhance standardised and equitable approaches towards the management of infertility in primary care.…”
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Implementing modified constraint-induced movement therapy after stroke in an early-supported discharge rehabilitation service: a process evaluation using RE-AIM QuEST by Ashan Weerakkody, Erin Godecke, Barby Singer

“…Despite extensive evidence supporting its efficacy and multiple clinical practice guidelines recommending its provision, very few eligible stroke survivors receive mCIMT internationally. …”
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Re-evaluating population-level screening recommendations to address increasing early-onset colorectal cancer rates in Australia: a modelling study☆ by J.-B. Lew, J. Worthington, H. Ge, Q. Luo, E. Feletto, K. Canfell, T. Price

“…These analyses supported the 2023 Clinical practice guidelines for the prevention, early detection and management of colorectal cancer: Population Screening, which led to the NBCSP including people aged 45-49 on an opt-in basis from July 2024.…”
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Comparative analysis of adolescent hypertension definitions for predicting early adulthood carotid artery intima-media thickness: Tehran lipid and glucose study by Maryam Barzin, Shirin Yaghoobpoor, Maryam Mahdavi, Behnaz Abiri, Majid Valizadeh, Fereidoun Azizi, Pooneh Dehghan, Farhad Hosseinpanah

“…Participants were categorized into normal blood pressure (BP), high-normal BP, HTN stage 1, and HTN stage 2 groups based on the childhood HTN definitions of the 4th report, European Society of Hypertension (ESH), and American Academy of Pediatrics Clinical Practice Guidelines (AAP-CPG). Akaike information criterion (AIC) and relative efficiencies (RE) were calculated to compare the ability of each to predict a high CIMT (≥95th percentile) during early adulthood. …”
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Utility of the Basophil Reactivity Test in the Clinical Management of People with Severe Uncontrolled Asthma by García Ródenas MDM, Hernández Blasco LM, Fernández Sánchez FJ, Marco de la Calle FM, Pascual-Lledó JF, Sánchez Barbie Á, Fernández Aracil C

“…However, there are no robust predictive markers of response to help clinicians select one of the multiple biologicals recommended in clinical practice guidelines. The aim of this study was to evaluate the utility of basophil reactivity, measured through the basophil activation test (BAT), as a marker of response to mAbs.Methods: We measured basophil reactivity, using anti-immunoglobulin E (anti-IgE) antibodies as a stimulus, in 72 consecutive patients with severe uncontrolled asthma before initiation of treatment with mAbs. …”
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