Alveolar cell composition in interstitial lung disease and the development of a pulmonary progressive fibrosing phenotype: a retrospective cohort study by Iris A. Simons, Bart G. Boerrigter, Maud C.M. Hovestadt, Kirsten A. Mooij-Kalverda, Shiqi Zhang, Leonoor S. Boers, Anke H. Maitland– van der Zee, Esther J. Nossent, Jan Willem Duitman

“…The identification of PPF was based on the criteria outlined in the ATS/ERS/JRS/ALAT clinical practice guidelines. Clinical data, pulmonary function tests, radiological imaging, and BAL cellular composition were collected. …”
Get full text

Predicting mucosal inflammation in IBD patients using patient-reported symptom scores and a faecal calprotectin home test: protocol for a multicentre prospective validation study by Lloyd Brandts, Zlatan Mujagic, M Pierik, Tessa EH Römkens, Laura Janssen, Mariëlle Romberg-Camps, Reinier Cornelis Anthonius van Linschoten, Rachel Louise West, Lennard P L Gilissen

“…The main study outcome is the diagnostic test accuracy of the various patient-reported scores to assess mucosal inflammation in combination with a FC home test.Ethics and dissemination This study is approved by the Medical Research Ethics Committee of azM/UM in Maastricht dated 03 March 2021 (METC 20–085) and is monitored by the Clinical Trial Centre Maastricht according to Good Clinical Practice guidelines. Written informed consent will be obtained from all patients. …”
Get full text

Palivizumab and prevention of childhood respiratory syncytial viral infection: protocol for a systematic review and meta-analysis of breakthrough infections by Meghan Sebastianski, Robin Featherstone, Shelly Jun, Joan Robinson

“…Should findings from this review necessitate updates to current clinical practice guidelines, we intend to establish a working group to engage relevant health administrators and decision makers.PROSPERO registration number CRD42019122120.…”
Get full text

Prevalence and related factors of psychological distress among cancer inpatients using routine Distress Thermometer and Chinese Health Questionnaire screening by Chiou YJ, Chiu NM, Wang LJ, Li SH, Lee CY, Wu MK, Chen CC, Wu YS, Lee Y

“…Yu-Jie Chiou,1 Nien-Mu Chiu,1 Liang-Jen Wang,2 Shau-Hsuan Li,3 Chun-Yi Lee,1 Ming-Kung Wu,1 Chien-Chih Chen,1 Yi-Shan Wu,1 Yu Lee1 1Department of Psychiatry, 2Department of Child and Adolescent Psychiatry, 3Department of Hematology-Oncology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan, Republic of China Background: Clinical practice guidelines suggest routine screening for distress among cancer patients for immediate early psychiatric care. …”
Get full text

Reframing spontaneous preterm birth as a preventable adverse outcome—A clinical audit of a preventative toolbox by Aparna Ramachandran, Darazel Perez, Adrienne Gordon, Jon Hyett

“…Abstract Introduction Spontaneous preterm birth is a major cause of perinatal morbidity and mortality and has traditionally been viewed as an inevitable event affecting a small proportion of pregnancies. Clinical practice guidelines recommend measures to predict pregnancies at risk of spontaneous preterm birth and prophylactic treatments. …”
Get full text

Personalized Digital Care Pathways Enable Enhanced Patient Management as Perceived by Health Care Professionals: Mixed-Methods Study by David Rodrigues, Clara Jasmins, Ricardo Ladeiras-Lopes, Luis Patrao, Eduardo Freire Rodrigues

“… Abstract BackgroundClinical decision support systems are known to improve adherence to clinical practice guidelines and patient outcomes by providing clinicians with timely, accurate, and appropriate knowledge. …”
Get full text

Acupuncture for stroke survivors with cardiovascular comorbidities: protocol of a pooled analysis of randomized controlled trials by Lanfang Zhang, Lanfang Zhang, Lanfang Zhang, Zubing Mei, Zhenhua Xu

“…The findings are expected to contribute to the evidence base regarding the efficacy and safety of acupuncture in this specific patient population, potentially influencing clinical practice guidelines and promoting the integration of acupuncture into standard stroke care protocols. …”
Get full text

Comparison between intratympanic injection of dexamethasone and methylprednisolone in idiopathic sudden sensorineural hearing loss: A randomized clinical trial by Kourosh Eftekharian, Elnaz Najafi, Maryam Amizadeh, Noosheen Mokari, Mohammad Faramarzi, Yalda Izadparast, Yalda Jabbari Moghadam, Ali Eftekharian

“…Three comparisons between the initial and third‐month hearing tests were made to assess the degree of hearing change: (1) pure tone improvement in each individual tone (0.5, 1, 2, 3, and 4 kHz); (2) word‐recognition score improvement; and (3) complete, partial, and no recovery of hearing calculated (as defined by American Academy of Otolaryngology‐Head and Neck Surgery Clinical Practice Guidelines). Results The study was completed with 69 of the 75 patients—34 in the methylprednisolone group and 35 in the dexamethasone group. …”
Get full text

Management of childhood-onset systemic lupus erythematosus (cSLE) over the last two decades in Spain by Alina Boteanu, Juan José Bethencourt, Joan Calzada-Hernández, Daniel Clemente, Juan Carlos Nieto-González, Covadonga López, Laura Luque, Inmaculada Calvo

“…A manual search was also performed with the above keywords, including “Clinical practice guidelines OR protocols OR recommendations”. …”
Get full text

Treatment Patterns and Health Care Costs in Commercially Insured Patients with Follicular Lymphoma by Nathan H. Fowler, Guifang Chen, Stephen Lim, Stephanie Manson, Qiufei Ma, Frank Li

“… # Conclusions The primary regimens used across treatment lines conform to those recommended by the National Comprehensive Cancer Network clinical practice guidelines. The economic burden for patients with FL is high and grows with subsequent lines of therapy.…”
Get full text

Change from semi‐rigid to soft collars for prehospital management of trauma patients: An observational study by Biswadev Mitra, Stephen Bernard, Cassandra Yankoff, Abha Somesh, Cara Stewart, Christine Koolstra, Carly Talarico, Ziad Nehme, Mark C. Fitzgerald, Peter A. Cameron

“…In 2021, Ambulance Victoria changed clinical practice guidelines to apply soft collars instead of semi‐rigid collars for suspected cervical spine injury. …”
Get full text

Summary of best evidence for prevention of postoperative pulmonary complications after surgery for patients undergoing gastric cancer operations by Mengnan Li, Guang Fu, Wenjuan Mo, Yuanyuan Yan

“…Therefore, researching and implementing effective prevention measures is crucial for improving patients’ postoperative quality of life and survival rates.AimTo collate and summarize the best available evidence for the prevention of pulmonary complications in patients undergoing gastric cancer surgery, thereby providing a reference for the clinical development of relevant intervention strategies.MethodsA literature search was conducted in databases including BMJ Best Practice, UpToDate, JBI, Cochrane Library, PubMed, Embase, the Ontario Nurses Registration Network, the U.S. National Clinical Practice Guidelines, and MedLine, for documents related to the prevention of pulmonary complications in gastric cancer surgery patients. …”
Get full text

Nonproteinuric Preeclampsia among Women with Hypertensive Disorders of Pregnancy at a Referral Hospital in Southwestern Uganda by Asiphas Owaraganise, Richard Migisha, Wasswa G. M. Ssalongo, Leevan Tibaijuka, Musa Kayondo, Godfrey Twesigomwe, Joseph Ngonzi, Henry Mark Lugobe

“…Nonproteinuric preeclampsia poses even greater diagnostic challenges due to contested diagnostic criteria by the clinical practice guidelines and variable clinical presentation. …”
Get full text

Patient and physical therapist perspectives on spinal manipulative therapy for low back pain and associated clinical outcomes: protocol for a prospective, single-arm intervention s... by Jason M Beneciuk, Guogen Shan, Joel Bialosky, Jill R Hayes, Katherine E Buzzanca-Fried, Robert Rowe, Sara Cristello, Trent Harrison, Ryan Vickers

“…Multimodal treatment approach of SMT (required during initial three treatment sessions within a 2week period), exercise and education supported by recent clinical practice guidelines will be encouraged for this study.Ethics and dissemination Ethics approval for the study was obtained from the University of Florida Institutional Review Board. …”
Get full text

Effect of music listening on delirium after hip fracture operations (MLDHFO) in a regional hospital in Taiwan: a randomised controlled trial protocol by Ling Wang, Lin-Yu Chao, Chun-Chih Lin, Hsing-Ju Lu, Jiun-Liang Chen, Han-Chang Ku

“…The trial will be carried out following the Declaration of Helsinki principles and Good Clinical Practice guidelines. Research data will be reported following Consolidated Standards of Reporting Trials guidelines and study results will be published in a peer-reviewed journal and presented at scientific conferences. …”
Get full text

The development and application of performance indicators to assess veterinarians’ adherence to the clinical practice Streptococcus suis in weaned pigs guideline by Isaura Y.A. Wayop, Jaap A. Wagenaar, Emely de Vet, Anke Lambooij, David C. Speksnijder

“…In 2014, the Streptococcus suis (S. suis) clinical practice guideline was introduced. To date, no information has been collected about the extent to which veterinarians were using this guideline. …”
Get full text

Stakeholders’ Perspectives on Quality Measurement of Oral Health Care in the Netherlands: A Qualitative Study by Amy Righolt, Denise Duijster, Kirsten Smits, Anke Oerlemans, Philip van der Wees, Stefan Listl

“…Facilitating factors were discussing quality in a trusted environment, and developing more clinical practice guidelines, which include meaningful quality measures. …”
Get full text

Home-based Intervention with Semaglutide Treatment of Neuroleptic-Related Prediabetes (HISTORI): protocol describing a prospective, randomised, placebo controlled and double-blinde... by Peter Haulund Gæde, Jan Frystyk, Niels Bilenberg, Ashok Ainkaran Ganeshalingam, Nicolai Gundtoft Uhrenholt, Sidse Arnfred

“…Exploratory outcomes encompass insulin sensitivity, cardiovascular risk profile, medication adherence, general well-being and physical activity.Ethics and dissemination This study will be carried out in accordance with the Declaration of Helsinki and Good Clinical Practice guidelines. This research has obtained approval from both the Danish Medicines Agency and The Regional Committees on Health Research Ethics for Southern Denmark.Trial registration number NCT05193578 European Clinical Trials Database Number (EudraCT) 2020-004374-22, Regional Ethical Committee number S-20200182.…”
Get full text

Surgery versus non-operative treatment for ER-stress unstable Weber-B unimalleolar fractures: a study protocol for a prospective randomized non-inferiority (Super-Fin) trial by Pasi Ohtonen, Tero Kortekangas, Harri Pakarinen, Simo Taimela, Teppo Jarvinen, Ristomatti Lehtola, Hannu-Ville Leskelä, Olli Savola

“…Depending on the trauma and the accompanying soft-tissue injury, these fractures are either stable or unstable. Current clinical practice guidelines recommend surgical treatment for unstable Weber B-type fibula fractures. …”
Get full text

Impact of 2014 Japanese practice guidelines on treatment patterns in patients with myasthenia gravis: an insurance claims database study by Akiyuki Uzawa, Shingo Konno, Makoto Samukawa, Izumi Mishiro, Hiroshi Todaka, Kentaro Taki, Céline Quelen, Adrianna Czubin, Renata Majewska, Kunihiko Shiraiwa, Yohei Ohashi

“…Objectives To evaluate changes in oral corticosteroid (OCS) use after the publication of the 2014 Japanese clinical practice guidelines for myasthenia gravis (MG).Design Retrospective cohort study performed in three Japanese health insurance databases: the JMDC database between 2005 and 2021; the DeSC database covering the National Health Insurance (NHI) and the DeSC database covering the Late-Stage Elderly Healthcare Service (LSEHS) between 2014 and 2021. …”
Get full text