Evaluation of the Glucose-Lowering Effect of Bloodletting Therapy in Type 2 Diabetes Mellitus by Tserentogtokh Baasantogtokh, Sainbileg Sonomtseren, Tsolmon Unurjargal, Rinchyenkhand Myagmardorj, Vaanchigsuren Seesregdorj, Bayarmagnai Lkhagvasuren, Vankhuu Enkhtuya, Seesregdorj Surenjid

“…Both groups received medicine according to the Mongolian Clinical Practice Guidelines for T2DM treatment. The experimental group additionally underwent bloodletting therapy on Day 6 of the study, following a 5-day preparation period during which they consumed 2.0 grams of a “3-seed decoction” (twice daily). …”
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Analysis of the Consumption of Medicinal Products Associated with a High Risk of Drug-Induced Liver Injury in Patients with COVID-19 by V. I. Petrov, A. Yu. Ryazanova, N. S. Tokareva

“…The authors identified medicines capable of causing clinically apparent liver damage (according to the LiverTox database and Russian clinical practice guidelines) and/or elevated liver enzymes in ≥1% of patients (according to safety reports).RESULTS. …”
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Collaborative tailoring of the Reach Out, Stay Strong Essentials (ROSE) program for pregnant veterans in the U.S. Veterans Health Administration: a qualitative case study of contex... by Erin P. Finley, Alison B. Hamilton, Ismelda Canelo, La Shawnta S. Jackson, Rachel Lesser, Rebecca S. Oberman, Julia Yosef, Joya G. Chrystal, Erica H. Fletcher, Bevanne Bean-Mayberry, Tannaz Moin, Melissa M. Farmer, Ariel J. Lang

“…., improving alignment with VA clinical practice guidelines) and adaptations to the implementation approach (e.g., offering training to VA providers beyond the original EMPOWER sites). …”
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Recommendations for the management of functional dyspepsia from the SEGHNP working group on motility and functional gastrointestinal disorders by Miguel Ángel Carro Rodríguez, Inmaculada Hidalgo Montes, Carmen Jovani Casano, Aránzazu Recio Linares, Etna Masip Simó, Gloria Rodrigo Garcia, Andrés Bodas Pinedo

“…As a result, there is evidence of substantial heterogeneity in the management of these patients due, in part, to the absence of clinical practice guidelines on this disease. Material and methods: A group was formed that consisted of 19 members of the working group on motility and functional gastrointestinal disorders (FGIDS) of the SEGHNP. …”
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The observational EURACAN prospective clinical registry dedicated to epithelioid hemangioendothelioma: The protocol of an international and collaborative effort on an ultra-rare en... by Anna Maria Frezza, Hugh Leonard, Ninna Aggerholm-Pedersen, Giuseppe Badalamenti, Paolo Baili, Giacomo G Baldi, Sebastian Bauer, Serena Bazzurri, Irene Benzonelli, Alexia Bertuzzi, Jean-Yves Blay, Giuseppe Bianchi, Simone Bonfarnuzzo, Christophe Bouvier, Kyetil Boye, Javier Martin Broto, Antonella Brunello, Domenico Campanacci, Paolo G Casali, Carlo Cicala, Elisa Crotti, Lorenzo D'Ambrosio, Angelo Paolo Dei Tos, Nils Dieckmann, Armelle Dufresne, Stephanie Elston, Virginia Ferraresi, Stefano Gabellini, Claudia Giani, Vincenzo Giannusa, Melissa Gil Sanjines, Teresa Grassani, Alessandro Gronchi, Paolo Lasalvia, Stefan Lindskog, Nadia Hindi, Matilde Ingrosso, Andrei Ivanescu, Robin Jones, Iwona Lugowska, Julia Ketzer, Anna Mariuk-Jarema, Alessandro Mazzocca, Laura Monteleone, Carlo Morosi, Andrea Napolitano, Francesca Nardozza, Elisabetta Neri, Maria Nilsson, Andri Papakonstantinou, Sandro Pasquali, Marta Sbaraglia, Federico Scolari, Joanna Szkandera, Claudia Valverde, Bruno Vincenzi, Salvatore Vizzaccaro, Federica Zuccheri, Silvia Stacchiotti, Annalisa Trama

“…VariablesFull details on patients and disease features, treatment and outcome will be collected, according to common clinical practice guidelines developed and shared with all the contributing centers. …”
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Guided self-determination intervention versus attention control for people with type 2 diabetes in outpatient clinics: a protocol for a randomised clinical trial by Christian Gluud, Jane Lindschou, Thordis Thomsen, Janus C Jakobsen, Vibeke Zoffmann, Anne Sophie Mathiesen, Tine Bruhn Skytte, Bodil Rasmussen, Emilie Marqvorsen, Mette Rothmann

“…Data will be collected using REDCap and analysed using Stata V.16.Ethics and dissemination The trial will be conducted in compliance with the protocol, the Helsinki Declaration in its latest form, International Harmonisation of Good Clinical Practice guidelines and the applicable regulatory requirement(s). …”
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Recomendaciones de manejo de la dispepsia funcional del Grupo de Trabajo de Motilidad y Trastornos Gastrointestinales Funcionales de la SEGHNP by Miguel Ángel Carro Rodríguez, Inmaculada Hidalgo Montes, Carmen Jovani Casano, Aránzazu Recio Linares, Etna Masip Simó, Gloria Rodrigo Garcia, Andrés Bodas Pinedo

“…As a result, there is evidence of substantial heterogeneity in the management of these patients due, in part, to the absence of clinical practice guidelines on this disease. Material and methods: A group was formed that consisted of 19 members of the working group on motility and functional gastrointestinal disorders (FGIDS) of the SEGHNP. …”
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Pulmonary function testing in pediatric allogeneic stem cell transplant recipients to monitor for Bronchiolitis obliterans syndrome: a systematic review by William A. Gower, Maximiliano Tamae-Kakazu, Shivanthan Shanthikumar, Saumini Srinivasan, Erin E. Reardon, Amisha V. Barochia, Edward Charbek, Charlotte Calvo, Pi Chun Cheng, Shailendra Das, Stella M. Davies, Jessica Gross, Ajay Sheshadri, Christoper T. Towe, Samuel B. Goldfarb, Narayan P. Iyer

“…A systematic review evaluating PFT before and after pediatric aHSCT was conducted to inform American Thoracic Society clinical practice guidelines on detection of BOS. Objective To determine the optimal approach to conducting PFT prior to and after pediatric aHSCT. …”
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Validation of a questionnaire to assess complexity of palliative care needs in primary care in Malaga, Spain: a study protocol by Jose Miguel Morales-Asencio, Rafael Gomez-Garcia, Pilar Barnestein-Fonseca, Francisca Leiva-Fernandez, Auxiliadora Fernández-López, Maria Luisa Martín-Roselló, Virginia Patricia Aguiar-Leiva

“…This protocol was conducted without patient or public participation.Ethics and dissemination This study evaluates a novel, co-designed tool to diagnose PC complexity to inform practice recommendations for a more efficient allocation of resources that may be included in future clinical practice guidelines. The study has been approved by the Provincial Research Ethics Committee of Málaga as of July 2023 and will be conducted in accordance with the principles established in the Declaration of Helsinki, the Council of Europe Convention on Human Rights and Biomedicine, and the requirements established in Spanish legislation. …”
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Web-Based Human Papillomavirus Education and Professional Skills Intervention for Health Care Providers: Protocol for a Randomized Controlled Trial by Jacob Martinez, Jacquelin I Cordero, Meagan Whitney, Katie L LaRoche, Gabriel Frietze, Eva M Moya, Kristin Gosselink

“…Tailored web-based educational programs for health care professionals, designed to address regional and patient population characteristics, may be a promising approach to enhancing the real-world implementation of clinical practice guidelines. Trial RegistrationClinicalTrials.gov NCT05120869; http://clinicaltrials.gov/ct2/show/NCT05120869 International Registered Report Identifier (IRRID)PRR1-10.2196/60790…”
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Diagnostic value of multiparametric ultrasound and the EU-TIRADS system for differentiation of focal thyroid lesions by A. V. Pomortsev, O. S. Tokarenko

“…In 2020, the EU-TIRADS system (2017) was included in Russian Clinical Practice Guidelines. Shear wave elastography (SWE) increases the diagnostic efficacy of ultrasonic B-mode examination of thyroid nodules and can be recommended to be included in the current classification system. …”
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Ендоскопічна хірургія пухлин надниркових залоз при первинному гіперальдостеронізмі by A. O. Nykonenko, I. V. Rusanov, I. V. Zubryk, O. O. Podluzhnyi, A. L. Makarenkov

“…Діагностику проводили згідно з Клінічними практичними рекомендаціями з діагностики та лікування первинного гіперальдостеронізму (Clinical Practical Guideline - The Management of  Primary Aldosteronism; 2008, 2016). …”
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The Effectiveness of Virtual Reality–Based Mindfulness Interventions for Managing Stress, Anxiety, and Depression: Protocol for a Systematic Review and Meta-Analysis of Randomized... by Ravi Shankar, Anjali Bundele, Amartya Mukhopadhyay

“…The findings will inform clinical practice guidelines for integrating VR-based mindfulness, guide technology development specifications, and establish evidence-based recommendations for health care policy regarding therapeutic VR reimbursement and regulatory frameworks. …”
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Association of serum 25-hydroxyvitamin D concentrations with risk of dementia among individuals with type 2 diabetes: A cohort study in the UK Biobank. by Tingting Geng, Qi Lu, Zhenzhen Wan, Jingyu Guo, Liegang Liu, An Pan, Gang Liu

“…Serum 25(OH)D ≥ 75 nmol/L was considered sufficient, according to the Endocrine Society Clinical Practice Guidelines. Incidence of all-cause dementia, AD, and VD cases was ascertained using electronic health records (EHRs). …”
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Utilization and dose optimization of beta-blockers in chronic heart failure therapy: a mixed-methods study by Sisay Sitotaw Anberbr, Tilaye Arega Moges, Abebech Tewabe Gelaye, Aragaw Dagnew Lakew, Samuel Berihun Dagnew, Gebremariam Wulie Geremew, Getachew Yitayew Tarekegn, Fisseha Nigussie Dagnew

“…Qualitative findings illuminated persistent barriers, including inadequate medication availability, suboptimal adherence to clinical practice guidelines, and patient compliance challenges. …”
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A Proposed Diagnostic and Treatment Algorithm for the Management of Lumbar Discogenic Pain by Lorio MP, Beall DP, Myers TJ, Naidu RK, McRoberts WP, Davis TT, Gage EG, Calodney AK, Verrills P, De Palma MJ, Amirdelfan K, Block JE

“…Corresponding treatment options were designated based on published degenerative disc disease (DDD)-specific clinical practice guidelines and/or meta-analyses.Results: This algorithm recommends a systematic rule set for discogenic pain diagnostic and treatment options. …”
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Prehospital antibiotics and intravenous fluids for patients with sepsis: protocol for a 2×2 factorial randomised controlled trial by Nick Daneman, Tony Mazzulli, Rob Stenstrom, Gail Klein, Ruxandra Pinto, Lisa Burry, Sheldon Cheskes, Jim Christenson, Damon C. Scales, Anna Rogowsky, Ian R. Drennan, Morgan Hillier, Sandra Jenneson, Philip Moran, Andrew M. Morris, Laurie J. Morrison, Gordon D. Rubenfeld, Christopher W. Seymour, P. Richard Verbeek

“…It will be conducted in accordance with the Declaration of Helsinki, Good Clinical Practice guidelines and regulatory requirements. The final results will be disseminated to participating paramedic services through educational materials, presentations and interactive training. …”
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Telmisartan modulates exercise responses in peripheral artery disease: Analyses of skeletal muscle from the TELEX Trial by Kate Kosmac, PhD, Jai K. Joshi, BS, Mary M. McDermott, MD, Jada C. Stewart, BS, Dongxue Zhang, MS, Shujun Xu, MS, Karen J. Ho, MD, Robert Sufit, MD, Luigi Ferrucci, MD, Charlotte A. Peterson, PhD, Ahmed Ismaeel, PhD

“…In participants with PAD randomized to supervised exercise, results suggested that TEL reduced myostatin expression and increased myofiber size, compared with placebo. Clinical practice guidelines recommend angiotensin-converting enzyme inhibitors/angiotensin receptor blockers in patients with hypertension and PAD to reduce cardiovascular events. …”
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Guideline-Directed Medical Therapy in the Management of Cardiovascular Disease: A Cross-sectional Questionnaire-based Study amongst Indian Healthcare Professionals by Prafulla Kerkar, Rajeev Garg, Abhishek Shukla, Viveka Kumar, Akshyaya Pradhan, Arindam Pande, Johan Christopher, Febin Francis, Nitin Zalte, Amarnath Sugumaran

“…Introduction: Guideline-Directed Medical Therapies (GDMT) are evidence-based treatments recommended by clinical practice guidelines for the management of Cardiovascular Diseases (CVDs). …”
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CARE Guidelines for Case Reports: Explanation and Elaboration Document. Translation into Russian by David S. Riley, Melissa S. Barber, Gunver S. Kienle, Jeffrey K. Aronson, Tido von Schoen-Angerer, Peter Tugwell, Helmut Kiene, Mark Helfand, Douglas G. Altman, Harold Sox, Paul G. Werthmann, David Moher, Richard A. Rison, Larissa Shamseer, Christian A. Koch, Gordon H. Sun, Patrick Hanaway, Nancy L. Sudak, Marietta Kaszkin-Bettag, James E. Carpenter, Joel J. Gagnier

“…Well-written and transparent case reports (1) reveal early signals of potential benefits, harms, and information on the use of resources; (2) provide information for clinical research and clinical practice guidelines, and (3) inform medical education. …”
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