Endoscopic variceal ligation combined with carvedilol versus endoscopic variceal ligation combined with propranolol for the treatment of oesophageal variceal bleeding in cirrhosis:... by Jing Wang, Meng Li, Lei Wang, Li Zhang, Ling Yang, Jian Wang, Duolao Wang, Rong Wang, Ya Peng, Chao Ma, Yiling Li, Yi Chen, Jing Xu, Xiaolong Qi, Hua Ye, Zhendong Jin, Hongyun Zhao, Wei Yan, Liwei Zhang, Chuan Liu, Andres Cardenas, Li Du, Ying Song, Biao Xie, Zhi Wei, Jianzhou Li, Wenhui Zhang, Qinghua Pan, Huiling Xiang, Shaoting Zhang, Shuairan Zhang, Xuan Liang, Shengjuan Hu, Lijun Peng, Xiaojie Zhang, Jingyi Xu, Xiaochao Liu, Huanhai Xu, Zhixu Fan, Lichun Shao, Pengyuan He, Qianlong Li, Yunhai Wu, Liyao Zhang, Dianliang Fang, Quanke Li, Dongli Xia, Yuchen Lv, Zongchao Zhang, Chaoguang Yan, Yuxia Wan, Haiming Fang, Wenlong Yang, Xiangman Zhang, Wei Rao, Xiurong Xia, Qiang Qiao, Ruimiao Yu, Changzhen Ren, Yuejun Yang, Zhenzhen Zhai, Xuejin Liu, Xingjun Lu, Yansheng Jia

“…The study will follow the Declaration of Helsinki and Good Clinical Practice guidelines. The findings of this trial will be disseminated through peer-reviewed publications, conference presentations and healthcare professionals to guide future clinical practice.Trial registration number Chinese Clinical Trial Registry (Registration number: ChiCTR2400089692).…”
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Application of the <italic>International Classification of Functioning, Disability and Health Rehabilitation Set</italic> in Rehabilitation of Patients with Knee Osteoarthritis in... by YAO Dong, HE Yiqi, ZHANG Qin, LIU Changhua, LI Taibiao, YAO Caiming, WANG Xiangfeng, WANG Qinfeng, HU Hongjun

“…Personalized rehabilitation programs were formulated according to the severity of functional disorders referring to the "<italic>Clinical Practice Guidelines of Traditional Chinese Medicine Rehabilitation for Knee Osteoarthritis</italic>". …”
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Impact of a Novel Insulin Management Service on Non-insulin Pharmaceutical Expenses by John E. Schneider, Anjani Parikh, Ivana Stojanovic

“…# Background Studies have shown that improvements in glycemic control are associated with avoidance or delayed onset of diabetes complications, improvements in health-related quality of life, and reductions in diabetes-related health care costs. Clinical practice guidelines recommend maintaining a hemoglobin A1c (HbA1c) level less than 7%, but among type 2 diabetes patients using insulin, two-thirds have HbA1c above 7% and one-third have HbA1c above 9%…”
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Palivizumab and prevention of childhood respiratory syncytial viral infection: protocol for a systematic review and meta-analysis of breakthrough infections by Meghan Sebastianski, Robin Featherstone, Shelly Jun, Joan Robinson

“…Should findings from this review necessitate updates to current clinical practice guidelines, we intend to establish a working group to engage relevant health administrators and decision makers.PROSPERO registration number CRD42019122120.…”
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Prevalence and related factors of psychological distress among cancer inpatients using routine Distress Thermometer and Chinese Health Questionnaire screening by Chiou YJ, Chiu NM, Wang LJ, Li SH, Lee CY, Wu MK, Chen CC, Wu YS, Lee Y

“…Yu-Jie Chiou,1 Nien-Mu Chiu,1 Liang-Jen Wang,2 Shau-Hsuan Li,3 Chun-Yi Lee,1 Ming-Kung Wu,1 Chien-Chih Chen,1 Yi-Shan Wu,1 Yu Lee1 1Department of Psychiatry, 2Department of Child and Adolescent Psychiatry, 3Department of Hematology-Oncology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan, Republic of China Background: Clinical practice guidelines suggest routine screening for distress among cancer patients for immediate early psychiatric care. …”
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Reframing spontaneous preterm birth as a preventable adverse outcome—A clinical audit of a preventative toolbox by Aparna Ramachandran, Darazel Perez, Adrienne Gordon, Jon Hyett

“…Abstract Introduction Spontaneous preterm birth is a major cause of perinatal morbidity and mortality and has traditionally been viewed as an inevitable event affecting a small proportion of pregnancies. Clinical practice guidelines recommend measures to predict pregnancies at risk of spontaneous preterm birth and prophylactic treatments. …”
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Personalized Digital Care Pathways Enable Enhanced Patient Management as Perceived by Health Care Professionals: Mixed-Methods Study by David Rodrigues, Clara Jasmins, Ricardo Ladeiras-Lopes, Luis Patrao, Eduardo Freire Rodrigues

“… Abstract BackgroundClinical decision support systems are known to improve adherence to clinical practice guidelines and patient outcomes by providing clinicians with timely, accurate, and appropriate knowledge. …”
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Acupuncture for stroke survivors with cardiovascular comorbidities: protocol of a pooled analysis of randomized controlled trials by Lanfang Zhang, Lanfang Zhang, Lanfang Zhang, Zubing Mei, Zhenhua Xu

“…The findings are expected to contribute to the evidence base regarding the efficacy and safety of acupuncture in this specific patient population, potentially influencing clinical practice guidelines and promoting the integration of acupuncture into standard stroke care protocols. …”
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Management of childhood-onset systemic lupus erythematosus (cSLE) over the last two decades in Spain by Alina Boteanu, Juan José Bethencourt, Joan Calzada-Hernández, Daniel Clemente, Juan Carlos Nieto-González, Covadonga López, Laura Luque, Inmaculada Calvo

“…A manual search was also performed with the above keywords, including “Clinical practice guidelines OR protocols OR recommendations”. …”
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Treatment Patterns and Health Care Costs in Commercially Insured Patients with Follicular Lymphoma by Nathan H. Fowler, Guifang Chen, Stephen Lim, Stephanie Manson, Qiufei Ma, Frank Li

“… # Conclusions The primary regimens used across treatment lines conform to those recommended by the National Comprehensive Cancer Network clinical practice guidelines. The economic burden for patients with FL is high and grows with subsequent lines of therapy.…”
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Summary of best evidence for prevention of postoperative pulmonary complications after surgery for patients undergoing gastric cancer operations by Mengnan Li, Guang Fu, Wenjuan Mo, Yuanyuan Yan

“…Therefore, researching and implementing effective prevention measures is crucial for improving patients’ postoperative quality of life and survival rates.AimTo collate and summarize the best available evidence for the prevention of pulmonary complications in patients undergoing gastric cancer surgery, thereby providing a reference for the clinical development of relevant intervention strategies.MethodsA literature search was conducted in databases including BMJ Best Practice, UpToDate, JBI, Cochrane Library, PubMed, Embase, the Ontario Nurses Registration Network, the U.S. National Clinical Practice Guidelines, and MedLine, for documents related to the prevention of pulmonary complications in gastric cancer surgery patients. …”
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Nonproteinuric Preeclampsia among Women with Hypertensive Disorders of Pregnancy at a Referral Hospital in Southwestern Uganda by Asiphas Owaraganise, Richard Migisha, Wasswa G. M. Ssalongo, Leevan Tibaijuka, Musa Kayondo, Godfrey Twesigomwe, Joseph Ngonzi, Henry Mark Lugobe

“…Nonproteinuric preeclampsia poses even greater diagnostic challenges due to contested diagnostic criteria by the clinical practice guidelines and variable clinical presentation. …”
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Home-based Intervention with Semaglutide Treatment of Neuroleptic-Related Prediabetes (HISTORI): protocol describing a prospective, randomised, placebo controlled and double-blinde... by Peter Haulund Gæde, Jan Frystyk, Niels Bilenberg, Ashok Ainkaran Ganeshalingam, Nicolai Gundtoft Uhrenholt, Sidse Arnfred

“…Exploratory outcomes encompass insulin sensitivity, cardiovascular risk profile, medication adherence, general well-being and physical activity.Ethics and dissemination This study will be carried out in accordance with the Declaration of Helsinki and Good Clinical Practice guidelines. This research has obtained approval from both the Danish Medicines Agency and The Regional Committees on Health Research Ethics for Southern Denmark.Trial registration number NCT05193578 European Clinical Trials Database Number (EudraCT) 2020-004374-22, Regional Ethical Committee number S-20200182.…”
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Surgery versus non-operative treatment for ER-stress unstable Weber-B unimalleolar fractures: a study protocol for a prospective randomized non-inferiority (Super-Fin) trial by Pasi Ohtonen, Tero Kortekangas, Harri Pakarinen, Simo Taimela, Teppo Jarvinen, Ristomatti Lehtola, Hannu-Ville Leskelä, Olli Savola

“…Depending on the trauma and the accompanying soft-tissue injury, these fractures are either stable or unstable. Current clinical practice guidelines recommend surgical treatment for unstable Weber B-type fibula fractures. …”
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Impact of 2014 Japanese practice guidelines on treatment patterns in patients with myasthenia gravis: an insurance claims database study by Akiyuki Uzawa, Shingo Konno, Makoto Samukawa, Izumi Mishiro, Hiroshi Todaka, Kentaro Taki, Céline Quelen, Adrianna Czubin, Renata Majewska, Kunihiko Shiraiwa, Yohei Ohashi

“…Objectives To evaluate changes in oral corticosteroid (OCS) use after the publication of the 2014 Japanese clinical practice guidelines for myasthenia gravis (MG).Design Retrospective cohort study performed in three Japanese health insurance databases: the JMDC database between 2005 and 2021; the DeSC database covering the National Health Insurance (NHI) and the DeSC database covering the Late-Stage Elderly Healthcare Service (LSEHS) between 2014 and 2021. …”
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Voices from the clinic: a qualitative analysis of physiotherapy strategies in musculoskeletal care for knee osteoarthritis patients by Jennifer Nguyen, Justine M. Naylor, Sarah Dennis, Rebecca Livings, Kathryn Mills, Siobhan M. Schabrun, Jeanette M. Thom

“…However, little is known about the extent to which physiotherapists adhere to clinical practice guidelines. This study aimed to explore the perspectives and care patterns of physiotherapists in Sydney, Australia on their delivery of knee osteoarthritis care and how this aligns with the 2019 Osteoarthritis Research Society International (OARSI) guidelines. …”
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Prospective exploration of the effect of adiposity and associated microbial factors on healing and progression of diabetic foot ulcers in Tanzania: study protocol of a longitudinal... by Fredirick Mashili, Agricola Joachim, Mabulla Mchembe, Faraja Chiwanga, Agbor Ako, Zulfiqar Abbas

“…Enrolling 150 participants per group will have a minimum power of 80% to detect a 20% difference in cumulative incidence of complete ulcer healing (at the 5% level of statistical significance) between the normal and high adiposity groups.Ethical considerations and dissemination of results This study will be conducted in compliance with the independent institutional review boards (IRBs), informed consent guidelines, the declaration of Helsinki and International Conference on Harmonisation, Good Clinical Practice Guidelines. Ethical clearance has been granted by the Muhimbili University of Health and Allied Sciences ethical review board (MUHAS Ref. …”
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A Cross-sectional Survey of Physicians to Understand Biomarker Testing and Treatment Patterns in Patients with Prostate Cancer in the USA, EU5, Japan, and China by Christian Gratzke, Himani Aggarwal, Jeri Kim, Holly Chaignaud, Sabine Oskar

“…Conclusions and clinical implications: Overall, testing rates increased following PARPi approval and updated clinical practice guidelines; yet, there was a wide variation in the proportions of patients with mCRPC recommended for testing, and perceived barriers to testing remain, suggesting unmet needs for patients and physicians. …”
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Predictors of lipoprotein(a) variability in clinical practice and their impact on cardiovascular risk by Hyung Joon Joo, Seung Gyu Yun, Jae Hyoung Park, Soon Jun Hong, Cheol Woong Yu, Seung Yong Shin, Eung Ju Kim

“…Integrating these findings into clinical practice guidelines has the potential to improve cardiovascular risk management at the population level, reduce healthcare disparities, and inform targeted public health interventions aimed at cardiovascular prevention.…”
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Phase I/II trial of intracerebral transplantation of autologous bone marrow stem cells combined with recombinant peptide scaffold for patients with chronic intracerebral haemorrhag... by Arisa Miura, Yoichi M Ito, Masahito Kawabori, Miki Fujimura, Kaoru Kahata, Hideo Shichinohe, Kenichiro Maeda, Masahiko Mukaino, Ryo Kogawa, Kentaro Nakamura, Shuho Gotoh, Kota Kurisu

“…Neurological assessments, MRI, 18F-fluorodeoxyglucose positron emission tomography and 123I-Iomazenil single-photon emission CT will be performed for 1 year after administration.Ethics and dissemination The trial protocols were reviewed and approved by the Institutional Review Board of the Hokkaido University Hospital (R5-11), and this study is conducted according to Good Clinical Practice guidelines and the principles of the Declaration of Helsinki. …”
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