E_N_T_R_O_P_Y: Monocentric analysis of rectal cancer radio-chemotherapy treatment in patients of young age by E. Meldolesi, A. Nicolì, N. Dinapoli, G. Chiloiro, A. Romano, R. Menghi, R. Persiani, F. Pacelli, C. Coco, C. Ratto, S. Manfrida, L. Boldrini, B. Corvari, M.A. Gambacorta

“…Results: All patients were classified in different risk groups, according to the ESMO 2017 rectal cancer clinical practice guidelines. 88 % of patients under 55 years old at the diagnosis belonged to the bad or advanced risk groups with an equal division. …”
Get full text

Systematic review and meta-analysis of T1 glottic cancer outcomes comparing CO2 transoral laser microsurgery and radiotherapy by Michael F. Vaculik, Colin A. MacKay, S. Mark Taylor, Johnathan R. B. Trites, Robert D. Hart, Matthew H. Rigby

“…Future prospective randomized controlled studies are required for confirming these findings and developing appropriate clinical practice guidelines. Level of evidence 2A; as per the Centre of Evidence Based Medicine.…”
Get full text

Treatment Patterns and Health Care Costs in Commercially Insured Patients with Follicular Lymphoma by Nathan H. Fowler, Guifang Chen, Stephen Lim, Stephanie Manson, Qiufei Ma, Frank Li

“…**Conclusions:** The primary regimens used across treatment lines conform to those recommended by the National Comprehensive Cancer Network clinical practice guidelines. The economic burden for patients with FL is high and grows with subsequent lines of therapy.…”
Get full text

Psychosocial and pharmacologic interventions for problematic methamphetamine use: Findings from a scoping review of the literature. by Mona Hersi, Kim Corace, Candyce Hamel, Leila Esmaeilisaraji, Danielle Rice, Nicole Dryburgh, Becky Skidmore, Gary Garber, Amy Porath, Melanie Willows, Paul MacPherson, Beth Sproule, Jorge Flores-Aranda, Chandlee Dickey, Brian Hutton

“…We conducted a scoping review of recent systematic reviews (SR), clinical practice guidelines (CPG), and primary controlled studies of psychosocial and pharmacologic treatments for MUD/PMU.…”
Get full text

Sequencing and Integration of Cervical Manual Therapy and Vestibulo-oculomotor Therapy for Concussion Symptoms: Retrospective Analysis by Christopher Kevin Wong, Lauren Ziaks, Samantha Vargas, Tessia DeMattos, Chelsea Brown

“…# Background After concussion many people have cervicogenic headache, visual dysfunction, and vestibular deficits that can be attributed to brain injury, cervical injury, or both. While clinical practice guidelines outline treatments to address the symptoms that arise from the multiple involved systems, no preferred treatment sequence for post-concussion syndrome has emerged…”
Get full text

Comparative effectiveness of manual therapy, pharmacological treatment, exercise therapy, and education for neck pain (COMPETE study): protocol of a systematic review with network... by Ana Izabela Sobral de Oliveira-Souza, Jordana Barbosa-Silva, Douglas P. Gross, Bruno R. da Costa, Nikolaus Ballenberger, Tiago V. Pereira, Liz Dennett, Susan Armijo-Olivo

“…Abstract Background and context of the study Neck pain is a prevalent and globally burdensome problem. Clinical practice guidelines have recommended conservative treatments such as education, exercise therapy (ET), manual therapy (MT), and pharmacological therapy (i.e., medication) to manage all types of neck pain based on the chronicity of the disease (acute, subacute, and chronic pain). …”
Get full text

Combined 25-hydroxyvitamin D concentrations and physical activity on mortality in US stroke survivors: findings from the NHANES by Junqi Liao, Jingyi Chen, Huimin Wu, Qing Zhu, Xiaogang Tang, Li Li, Aimei Zhang, Peiyi Mo, Yan Liu, Xinyi Yang, Yang Han, Zhaoyao Chen, Wenlei Li, Yuan Zhu, Minghua Wu

“…These findings provide new ideas and possibilities for the prevention and treatment of cardiovascular and cerebrovascular diseases, offering a reference for development of clinical practice guidelines in the future.…”
Get full text

Trends in clinical encounters and management for infertility among women attending Australian general practice: a national longitudinal study using MedicineInsight, 2011 to 2021 by Alice R Rumbold, Michael Davies, Danielle Mazza, Jacqueline Boyle, Vivienne Moore, Renae C Fernandez, Luke E Grzeskowiak

“…These findings support the development of clinical practice guidelines to enhance standardised and equitable approaches towards the management of infertility in primary care.…”
Get full text

Pharmacokinetics and pharmacodynamics of ciprofol after continuous infusion in elderly patients by Xiaowen Guo, Yang Qiao, Sijie Yin, Fengqin Luo, Lingmei Yi, Jiajia Chen, Man Lu

“…The pre-registration date was June 20, 2021, and the review approval and official case solicitation began in December 2021; Retrospectively registered) was conducted in accordance with the World Medical Congress Declaration of Helsinki and Good Clinical Practice guidelines. All study subjects provided written informed consent.…”
Get full text

Evaluating the Impact of Pharmacotherapy in Augmenting Quit Rates Among Hispanic Adults in an App-Delivered Smoking Cessation Intervention: Secondary Analysis of a Randomized Contr... by Margarita Santiago-Torres, Kristin E Mull, Brianna M Sullivan, Ana Paula Cupertino, Ramzi G Salloum, Matthew Triplette, Michael J Zvolensky, Jonathan B Bricker

“…ObjectiveThis secondary analysis used data from a randomized controlled trial that compared the efficacy of 2 smoking cessation apps, iCanQuit (based on acceptance and commitment therapy) and QuitGuide (following US clinical practice guidelines), to explore the association between pharmacotherapy use and smoking cessation outcomes among the subsample of 173 Hispanic participants who reported on pharmacotherapy use. …”
Get full text

Evidence-based ankle pump exercise in prevention of postoperative deep-vein thrombosis in patients with lower extremity fracture (踝泵运动预防下肢骨折患者围手术期深静脉血栓的循证实践)... by BAO Xiuhong (鲍秀红), ZHANG Fang (张芳), ZHU Yi (朱屹), SHAO Ye (邵烨)

“…Methods CNKI, Wanfang, VIP, Medlive, BMJ, Cochrane library, Embase, PubMed, RNAO, ESPEN, NGC and NICE were searched for clinical practice guidelines, systematic reviews and relevant papers from August 2012 to August 2012. …”
Get full text