Editorial: Psychosocial issues and interventions in pulmonary rehabilitation by Ingeborg Farver-Vestergaard, Ingeborg Farver-Vestergaard, Eleonora Volpato, Eleonora Volpato, Eleonora Volpato, Henrik Hansen, Henrik Hansen, Henrik Hansen, Liz Steed

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Response to: Comment #2 on “Differences in Ventilatory Threshold for Exercise Prescription in Outpatient Diabetic and Sarcopenic Obese Subjects” by Gian Pietro Emerenziani, Maria Chiara Gallotta, Silvia Migliaccio, Emanuela A. Greco, Chiara Marocco, Luca di Lazzaro, Rachele Fornari, Andrea Lenzi, Carlo Baldari, Laura Guidetti

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Signal and modulating role of enzymes of digestive glands by G. F. Korotko

“…Enzymergic regulation of visceral functions, including sensory, alimentiry, protective, acts as new section of up-to-date science and, according to accumulated facts, is promising in gastroenterology, pancreatology, oncology, immunology and other segments of clinical medicine.…”
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Inflammation in Cachexia by M. Seelaender, A. Laviano, S. Busquets, G. P. Püschel, T. Margaria, M. L. Batista

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Effectiveness of the Strategies Implemented in Sri Lanka for Controlling the COVID-19 Outbreak by K. K. W. H. Erandi, A. C. Mahasinghe, S. S. N. Perera, S. Jayasinghe

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An Uncommon Manifestation of a Great Imitator: Gummatous Syphilis of the Liver in an HIV-Positive Patient by Nadia Solomon, Tom Heller, Tommaso Manciulli, Paola Del Giacomo, Katleen de Gaetano Donati, Enrico Brunetti, Francesco Taccari

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The clinical method in pediatrics by Luis Hernández Sosa, Sonia Pérez García, María Casanova González

“…The application of the clinical method in children health care is a fundamental tool because it is a system of thoughts implemented to solve problems that may appear when implementing clinical medicine. Nevertheless, it has some particularities, scientific foundations and some art. …”
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Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells by Chu-An Wang, Ya-Chin Hou, Yi-Kai Hong, Yu-Jing Tai, Chieh Shen, Pei-Chi Hou, Jhao-Lin Fu, Cheng-Lin Wu, Siao Muk Cheng, Daw-Yang Hwang, Yung-Yeh Su, Yan-Shen Shan, Shaw-Jenq Tsai

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The association of body roundness index and body mass index with frailty and all-cause mortality: a study from the population aged 40 and above in the United States by Jianqiang Zhang, Huifeng Zhang

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Exploring SLEEPINESS through home monitoring with ultra-long-term subcutaneous EEG and ecological momentary assessment in sleepy treatment naïve obstructive sleep apnea patients st... by Mathias Sarkez-Knudsen, Martin Ballegaard, Martin Ballegaard, Henning Piilgaard, Esben Ahrens, Martin Christian Hemmsen, Tobias Søren Andersen, Jakob Eyvind Bradram, Preben Homøe, Preben Homøe

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Safety of interleukin inhibitors in patients with plaque psoriasis and history of neoplasms: a multicenter retrospective study – IL PSO (Italian landscape psoriasis) by Mario Valenti, Luciano Ibba, Sara Di Giulio, Luigi Gargiulo, Piergiorgio Malagoli, Anna Balato, Carlo G. Carrera, Paolo Dapavo, Eugenia V. Di Brizzi, Valentina Dini, Francesca Gaiani, Francesco Loconsole, Angelo V. Marzano, Matteo Megna, Alessandra Michelucci, Luca Potestio, Simone Ribero, Antonio Costanzo, Alessandra Narcisi

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Deciphering the Transcriptional Metabolic Profile of Adipose-Derived Stem Cells During Osteogenic Differentiation and Epigenetic Drug Treatment by Giulia Gerini, Alice Traversa, Fabrizio Cece, Matteo Cassandri, Paola Pontecorvi, Simona Camero, Giulia Nannini, Enrico Romano, Francesco Marampon, Mary Anna Venneri, Simona Ceccarelli, Antonio Angeloni, Amedeo Amedei, Cinzia Marchese, Francesca Megiorni

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Comprehensive Sepsis Risk Prediction in Leukemia Using a Random Forest Model and Restricted Cubic Spline Analysis by Kou Y, Tian Y, Ha Y, Wang S, Sun X, Lv S, Luo B, Yang Y, Qin L

“…Yanqi Kou,1,2,* Yuan Tian,2,3,* Yanping Ha,2,3,* Shijie Wang,1,* Xiaobai Sun,1 Shuxin Lv,1 Botao Luo,2,3 Yuping Yang,2 Ling Qin1 1Department of Hematology, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, Henan Province, People’s Republic of China; 2Department of Gastroenterology, Affiliated Hospital of Guangdong Medical University, Guangdong Medical University, Zhanjiang City, Guangdong Province, People’s Republic of China; 3Department of Pathology, Guangdong Medical University, Zhanjiang City, Guangdong Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yuping Yang, Department of Gastroenterology, Affiliated Hospital of Guangdong Medical University, Guangdong Medical University, No. 2 Wenming East Road, Xiashan, Zhanjiang, Guangdong, 524000, People’s Republic of China, Email yangyupingchn@163.com Ling Qin, Department of Hematology, The First Affiliated Hospital and College of Clinical Medicine, Henan University of Science and Technology, 24 Jinghua Road, Jianxi District, Luoyang, Henan Province, 471003, People’s Republic of China, Email zzqq777@126.comBackground: Sepsis is a severe complication in leukemia patients, contributing to high mortality rates. …”
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A preliminary exploration of establishing a mice model of hypoxic training by Minglu Li, Zhijie Chen, Ziyang He, Xinjuan Zhang, Yanqiu Liu, Hui Zhou, Hang Yang, Tao Liu, Xiaochuan Wang, Ran Zhang, Jiaxing Zhang

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Deep learning-based algorithm for classifying high-resolution computed tomography features in coal workers’ pneumoconiosis by Hantian Dong, Biaokai Zhu, Xiaomei Kong, Xuesen Su, Ting Liu, Xinri Zhang

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Effect of Acetyl tributyl citrate on bone metabolism based on network toxicology and molecular docking technology by Xuan Lin, Kun Lin, Yue Lai, Qingping Peng, Miao Xu, Yiting Xu, Jialin Yang, Huan Liu, Jianlin Shen

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Randomised, placebo-controlled, double-blinded, four-way crossover trial to demonstrate the comparative pharmacodynamic equivalence of a non-invasive diagnostic test for adrenal in... by Judith Cohen, Miguel Debono, Kathleen Baster, Richard J Ross, Charlotte J Elder, Kathryn L Date, Sharon L Caunt, Jane Fearnside, Trevor N Johnson, Rosie N Taylor

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Transaxillary vs. Transsubclavian Gasless endoscopic thyroidectomy approaches for papillary thyroid cancer by Hongji Wu, Meiyu Zhu, Chi Ma, Rui Yang, Yanzhong Gu, Shujian Wei, Xincheng Liu, Haiqing Sun, Guibin Zheng, Xicheng Song, Haitao Zheng

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Unsupervised machine learning model for phenogroup-based stratification in acute type A aortic dissection to identify postoperative acute gastrointestinal injury by Yuhu Ma, Xiaofang Yang, Chenxiang Weng, Xiaoqing Wang, Baoping Zhang, Ying Liu, Rui Wang, Zhenxing Bao, Peining Yang, Hong Zhang, Yatao Liu

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Construction of a novel radioresistance-related signature for prediction of prognosis, immune microenvironment and anti-tumour drug sensitivity in non-small cell lung cancer by Yanliang Chen, Chan Zhou, Xiaoqiao Zhang, Min Chen, Meifang Wang, Lisha Zhang, Yanhui Chen, Litao Huang, Junjun Sun, Dandan Wang, Yong Chen

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