Epigenetic and Neurological Impairments Associated with Early Life Exposure to Persistent Organic Pollutants by Nathalie Grova, Henri Schroeder, Jean-Luc Olivier, Jonathan D. Turner

“…In many ways, this expands the classical “Developmental Origins of Health and Disease” paradigm to include exposure to pollutants. …”
Get full text

Returns to scale in decision-making units with integer-valued or mixed inputs and integer-valued or real outputs using radial models in data envelopment analysis by Zeinab Tavassoli, Mohsen Rostami-MalKhalifeh, Farhad Hosseinzadeh Lotfi, Tofigh allahVieanloo

“…The existence of a difference between the results produced by our proposed model and those of the classical model was demonstrated through two examples, one using hypothetical data and the other real-world data.…”
Get full text

Neural mechanisms of fairness decision-making: An EEG comparative study on opportunity equity and outcome equity by Qi Li, Ya Zheng, Jing Xiao, Kesong Hu, Zhong Yang

“…Our study used a modified version of the ultimatum game (UG) and the classic UG, and recorded electroencephalogram (EEG) data to investigate underlying neural mechanisms of fairness decision-making of opportunity equity and outcome equity. …”
Get full text

Th17/Treg balance is regulated during the suppression of experimental autoimmune encephalomyelitis treated by Astragalus polysaccharides via the microbiota-gut-brain axis by Jinyun Ma, Xiaojun Liu, Yan Zhao, Qijin Lu, Guiqing Ding, Yuanhua Wang, Xiaodong Cheng

“…Our previous studies have shown that Astragalus polysaccharide (APS) has a role in alleviating the clinical symptoms and demyelination of experimental autoimmune encephalomyelitis (EAE) mice, a classic MS model. However, the mechanism of action is not fully understood. …”
Get full text

Single-cell RNA sequencing of circulating immune cells supports inhibition of TNFAIP3 and NFKBIA translation as psoriatic arthritis biomarkers by Ameth N. Garrido, Rohan Machhar, Omar F. Cruz-Correa, Darshini Ganatra, Sarah Q. Crome, Sarah Q. Crome, Joan Wither, Joan Wither, Joan Wither, Igor Jurisica, Igor Jurisica, Igor Jurisica, Dafna D. Gladman, Dafna D. Gladman, Dafna D. Gladman

“…Differentially expressed genes (DEGs) identified through scRNA-seq were validated on classical monocytes, and CD4+ and CD8+ T cell subsets derived from an independent cohort of patients using the NanoString nCounter® platform. …”
Get full text

A stomatal optimization model integrating leaf stomata-photosynthetic capacity regulation in response to soil water stress by Yong Liu, Tiesong Hu, Rui Zhu, Qiuwen Chen, Xiang Zeng, Peiran Jing, Yifan Huang

“…Additionally, the SRSC model reasonably predicted a coordinated decline in gs and Vcmax25 and concurrently mitigated the classical models that simulate gs and leaf water potential responses deviating from the actual values under drought conditions. …”
Get full text

Mechanisms Predisposing Penile Fracture and Long-Term Outcomes on Erectile and Voiding Functions by Leonardo O. Reis, Marcelo Cartapatti, Rafael Marmiroli, Eduardo Jeronimo de Oliveira Júnior, Ricardo Destro Saade, Adriano Fregonesi

“…Among the 44 suspicious cases, 42 (95.4%) were confirmed, mean age was 34.5 years (range: 18–60), mean follow-up 59.3 months (range 9–155). Half presented the classical triad of audible crack, detumescence, and pain. …”
Get full text

Identification of a functional vitamin D response element in the promoter of goose anti-Müllerian hormone gene by Rong Chen, Chen Chen, Yifei Qin, Jie Liu, Mingming Lei, Huanxi Zhu, Zhendan Shi

“…The results showed that AMH mRNA expressions were downregulated by vitamin D3 in granulosa cells of prehierarchical follicles in geese. A classical VDRE-like sequence was identified in the goose AMH promoter by in silico analyses. …”
Get full text

Knights in shining armour and (M)others in life jackets: Women’s experiences of advocating for care alone when suffering recurrent early pregnancy loss during the SARS-CoV-2 pandem... by Flora E. Kent-Nye, Kayleigh S. Sheen, Karen Burgess, Munira Oza, Laura A. Magee, Davor Jurković, Sergio A. Silverio

“…Data were recorded, transcribed, and analysed by hand, following a Classical Grounded Theory Analysis, appropriate for cross-disciplinary health research. …”
Get full text

G-cleave LC3B biosensor: monitoring autophagy and assessing resveratrol's synergistic impact on doxorubicin-induced apoptosis in breast cancer cells by Chiao-Chun Liao, Yuqing Long, Ming-Lin Tsai, Chun-Yu Lin, Kai-Wen Hsu, Chia-Hwa Lee

“…In this study, we developed a non-invasive autophagy detection system (NIADS-autophagy, also called G-cleave LC3B biosensor) by integrating a split-luciferase-based biosensor with an LC3B cleavage sequence, which swiftly identified classic autophagic triggers, such as Earle's Balanced Salt Solution and serum deprivation, through protease-mediated degradation pathways. …”
Get full text

Analysis of GAA Junction Less NS FET Towards Analog and RF Applications at 30 nm Regime by Asisa Kumar Panigrahy, Sudheer Hanumanthakari, Shridhar B. Devamane, Shruti Bhargava Choubey, M. Prasad, D. Somasundaram, N. Kumareshan, N. Arun Vignesh, Gnanasaravanan Subramaniam, Durga Prakash M, Raghunandan Swain

“…The performance of both the classical and quantum models of the GAA nanosheet device is evaluated using the visual TCAD tool, which measures the <italic>I_ON</italic>, <italic>I_OFF</italic>, <italic>I_ON&#x002F; I_OFF</italic>, threshold voltage, DIBL, gain parameters (g_m, g_d, A_v), gate capacitance, and cut-off frequency (<italic>f_T</italic>). …”
Get full text

Flow Cytometry Evaluation of Blood-Cell-Bound Surface FVIII in Hemophilia A and Thrombosis by Anjud Al-Mohannadi, Reem Mohammed Yahia, Hani Bibawi, Che-Ann Lachica, Watfa Ahmed, Igor Pavlovski, Giusy Gentilcore, Elkhansa Elbukhari Elgaali, Anila Ejaz, Areeg Ahmed, Mohammed Elanbari, Zainab Awada, Mohammed J. Al-Kubaisi, Muhammad Elnaggar, Ayman Saleh, Chiara Cugno, Sara Deola

“…Intriguingly, when analyzing the distinct blood subpopulations, we observed that surface FVIII levels were significantly elevated in classical monocytes of thrombosis patients compared to HA patients, healthy controls, and patients with other coagulopathies. …”
Get full text

CO2-Driven Hydraulic Fracturing Trajectories across a Preexisting Fracture by Qi Zhang, Jiehao Wang, Yufeng Gao, Shengfei Cao, Jingli Xie, Like Ma, Yuemiao Liu

“…The model couples rock deformation and gas seepage using the finite element method and is validated against classical theoretical analysis. The simulation results define four basic intersection scenarios between the fluid-driven and preexisting fractures: (a) inserting—the hydraulic fracture inserts into a bedding plane and continues to propagate along it; (b) L-shaped crossing—the hydraulic fracture approaches the fracture/bedding plane then branches into the plane without crossing it; (c) T-shaped crossing—the hydraulic fracture approaches the fracture/bedding plane, branches into it, and crosses through it; (d) direct crossing—the hydraulic fracture crosses one or more bedding planes without branching into them. …”
Get full text

Lyme neuroborreliosis as initial expression of Lyme disease in an elderly patient by Emidio Mata, Bárbara Lage Garcia, André Pereira, Joana Rego, Flávia Santos, Carlos Fernandes, Jorge Cotter

“…Early neurological symptoms, often preceding classic cutaneous signs, may lead to diagnostic delays. …”
Get full text

Cannabinoid receptor 2 selective agonist ameliorates adjuvant-induced arthritis by modulating the balance between Treg and Th17 cells by Na Tian, Cui Yang, Yu Du, Miao Chen, Bin Li, Bin Li, Bin Li, Bin Li, Bin Li, Dan Li, Sheng-Ming Dai

“…BackgroundAdjuvant-induced arthritis (AIA) serves as a classic model for rheumatoid arthritis (RA), typified by inflammatory cell infiltration and joint damage. …”
Get full text

Writing a case report of Traditional Chinese Medicine nursing (浅谈中医护理个案书写) by ZHANG Lijuan (张丽娟), WANG Bei (王蓓)

“…As an important part of classical literature of Traditional Chinese medicine (TCM), the case study report of Traditional Chinese Medicine nursing vividly reflects the actual situation and characteristics of TCM diagnosis and treatment. …”
Get full text

Investigation of FDM-Based 3D Printing for Optimized Tooling in Automotive and Electronics Sheet Metal Cutting by Szabolcs Szalai, Brigitta Fruzsina Szívós, Vivien Nemes, György Szabó, Dmytro Kurhan, Mykola Sysyn, Szabolcs Fischer

“…With this research, the authors wanted to demonstrate that FDM technology can also be used to produce a classic sheet cut, which, of course, is still of great importance for prototyping or setting up production processes. …”
Get full text

Towards a Noninvasive Intracranial Tumor Irradiation Using 3D Optical Imaging and Multimodal Data Registration by R. Posada, Ch. Daul, D. Wolf, P. Aletti

“…In the case of intracranial tumors, classical methods of patient positioning in the irradiation machine coordinate system are invasive and only allow for CRT in one irradiation session. …”
Get full text

Studies on wear resistance of the radial bearing design taking into account rheological properties of micropolar lubricant by M. A. Mukutadze, H. N. Abdulrahman, V. E. Shvedova, G. A. Badakhov, N. V. Zinoviev

“…New models are obtained on the basis of classical equations in the «thin layer» approximation and the continuity equation, which describes the turbulent mode of motion of a lubricant with micropolar rheological properties. …”
Get full text

Effect of High, Medium, and Low Molecular Weight Hyaluronan on Inflammation and Oxidative Stress in an In Vitro Model of Human Nasal Epithelial Cells by Giusy Daniela Albano, Anna Bonanno, Luca Cavalieri, Eleonora Ingrassia, Caterina Di Sano, Liboria Siena, Loredana Riccobono, Rosalia Gagliardo, Mirella Profita

“…The HMW-HA might represent a coadjuvant of the classic anti-inflammatory/antioxidative treatment of nasal epithelial cells during IL-17A nasal inflammation.…”
Get full text