Successful Modified Therapy in a Patient with Probable Infection-Associated Hemophagocytic Lymphohistiocytosis by Carl L. Kay, Matthew J. Rendo, Paul Gonzales, Sead G. Beganovic, Magdalena Czader

“…While the disease is often fatal, classic management of HLH revolves around early diagnosis and initiation of protocolized therapy. …”
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Constraint Trajectory Surface-Hopping Molecular Dynamics Simulation of the Photoisomerization of Stilbene by Yibo Lei, Shaomei Wu, Chaoyuan Zhu, Zhenyi Wen, Sheng-Hsien Lin

“…Combining trajectory surface hopping (TSH) method with constraint molecular dynamics, we have extended TSH method from full to flexible dimensional potential energy surfaces. Classical trajectories are carried out in Cartesian coordinates with constraints in internal coordinates, while nonadiabatic switching probabilities are calculated separately in free internal coordinates by Landau-Zener and Zhu-Nakamura formulas along the seam. …”
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From Transmission Error Measurements to Angular Sampling in Rotating Machines with Discrete Geometry by Didier Remond, Jarir Mahfoudh

“…It then becomes possible to compare these harmonics under different operating conditions, especially when speed varies, without changing any parameters in spectral analysis (window length, spectral resolution, etc.). Moreover, classical techniques of improving signal to noise ratio by averaging become fully efficient in the detection of defective elements. …”
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An Integral Numerical Analysis of Impact of a Commercial Aircraft on Nuclear Containment by Xiaoxin Wang, Qin Zhou, Li Shi, Haitao Wang, Xiaotian Li

“…The fuel distribution in the aircraft is found to have strong influence on the damage of the containment, which indicates that the load distribution in the transverse direction is critical in the analysis of aircraft impact. The classic load-time function analysis is unable to incorporate this factor and may not be adequate to provide satisfactory results. …”
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Pre-Descemet Corneal Dystrophy – Changes in Corneal Morphology in Confocal Microscopy by Urszula Kołodziejska, Anna K. Kurowska, Jacek P. Szaflik, Jerzy Szaflik

“…In vivo confocal microscopy is a useful tool in diagnosing rare corneal dystrophies in cases where classical examination methods give inconclusive results.…”
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A Novel MEGNet for Classification of High-Frequency Oscillations in Magnetoencephalography of Epileptic Patients by Jun Liu, Siqi Sun, Yang Liu, Jiayang Guo, Hailong Li, Yuan Gao, Jintao Sun, Jing Xiang

“…After optimized configuration, the accuracy, precision, recall, and F1-score of the proposed detector reached 94%, 95%, 94%, and 94%, which were better than other classical machine learning models. In addition, we used the k-fold cross-validation scheme to test the performance consistency of the model. …”
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Deep reinforcement learning for active flow control in a turbulent separation bubble by Bernat Font, Francisco Alcántara-Ávila, Jean Rabault, Ricardo Vinuesa, Oriol Lehmkuhl

“…Abstract The control efficacy of deep reinforcement learning (DRL) compared with classical periodic forcing is numerically assessed for a turbulent separation bubble (TSB). …”
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Chemical and Immunological Characteristics of Aluminum-Based, Oil-Water Emulsion, and Bacterial-Origin Adjuvants by Susana Martiñón, Angel Cisneros, Sergio Villicaña, Ricardo Hernández-Miramontes, Edgar Mixcoha, Psyché Calderón-Vargas

“…This minireview summarizes the mechanisms that classic and novel adjuvants produce to stimulate immune responses.…”
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Output current observation and control of grid-connected modular multilevel converter using a simplified super twisting algorithm sliding mode by Imane Alia, Imad Merzouk, Mehamed Mounir Rezaoui, Hegazy Rezk, Abderezak Lashab

“…The results demonstrate that SSTA-SMC and SSTA-SMLO surpass the classic methods.…”
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Splenectomy for Solitary Splenic Metastasis in Recurrent Papillary Thyroid Cancer. A Case Report and Literature Review by Antonio Maffuz-Aziz, Gabriel Garnica, Silvia López-Hernández, Janet Pineda-Diaz, Javier Baquera-Heredia, Patricia López-Jiménez

“…About 7-23% of the patients will present recurrent metastases disease during follow-up. The classic variant of papillary carcinoma is less aggressive compared to its other variants like diffuse sclerosing, tall cell or columnar cell, and insular variants, and the sites to which this metastasizes is already well identified. …”
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On Regularization of an Optimal Control Problem for Ill-Posed Nonlinear Elliptic Equations by Peter I. Kogut, Olha P. Kupenko, Rosanna Manzo

“…To overcome this difficulty, we make use of a variant of the classical Tikhonov regularization scheme. In particular, we eliminate the PDE constraints between control and state and allow such pairs run freely by introducing an additional variable which plays the role of “compensator” that appears in the original state equation. …”
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Properties and Applications of Neutrosophic Burr XII Distribution by Laila A. Al-Essa, Farrukh Jamal, Shakaiba Shafiq, Sadaf Khan, Qamer Abbas, Rehan Ahmad Khan Sherwani, Muhammad Aslam

“…Abstract Primarily, when the hazards function has intricate structures, the BrXII distribution is an established framework for lifetime data analysis. However, classical probability models are limited in the sense that they cannot measure or record the data in exactness fueling the notion of indeterminacy in data collection process. …”
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A Coupled Elastoplastic Damage Dynamic Model for Rock by Xuelong Hu, Ming Zhang, Xiangyang Zhang, Min Tu, Zhiqiang Yin, Haifeng Ma, Minke Duan

“…In this model, unified strength theory is taken as the yield criterion; to reflect the different damage evolution law of rocks under tension and pressure conditions, the effective plastic strain and volumetric plastic strain are used to represent the compressive damage variable and the equivalent plastic strain is used to represent the tensile damage variable; the plastic hardening behavior and strain rate effect of rocks are characterized by piecewise function and dynamic increase factor function, respectively; Fortran language and LS-DYNA User-Defined Interface (Umat) are used to numerically implement the constitutive model; the constitutive model is verified by three classical examples of rock uniaxial and triaxial compression tests, rock uniaxial tensile test, and rock ballistic test. …”
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Adaptive Control Design for Human Handwriting Process Based on Electromyography Signals by Imane Mahmoud, Ines Chihi, Afef Abdelkrim

“…As a first step, we develop the application of the classic proportional integral structure (PI). The PI controller was applied to generate different essays of handwritten graphic traces in one-writer case and multiwriter case. …”
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Metrology with a twist: probing and sensing with vortex light by Mingjian Cheng, Wenjie Jiang, Lixin Guo, Jiangting Li, Andrew Forbes

“…This review aims to provide a comprehensive overview of recent advances and future trends in optical metrology with structured light, specifically focusing on how utilizing vortex beams has revolutionized metrology and remote sensing, transitioning from classical to quantum approaches.…”
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Two-Round Diagnosability Measures for Multiprocessor Systems by Jiarong Liang, Qian Zhang, Changzhen Li

“…Based on the abovementioned theories, for the n-dimensional hypercube Qn, we show that its two-round diagnosability is n2+n/2, which is n+1/2 times its classic diagnosability. Furthermore, a fault diagnosis algorithm is proposed to identify each node in the system under the PMC model. …”
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Bisphosphonate Treatment in a Patient Affected by MPS IVA with Osteoporotic Phenotype by Albina Tummolo, Orazio Gabrielli, Alberto Gaeta, Maristella Masciopinto, Lucia Zampini, Luigi Michele Pavone, Paola Di Natale, Francesco Papadia

“…Morquio A syndrome (Mucopolysaccharidosis type IVA) (MPS IVA) is a rare inherited metabolic disorder characterized by the defective degradation of keratan sulfate and chondroitin-6-sulfate. Classically, MPS IVA patients present with severe multisystemic involvement and have a short life expectancy. …”
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Functional genomics implicates ebony in the black pupae phenotype of tephritid fruit flies by Daniel F. Paulo, Thu N. M. Nguyen, Chris M. Ward, Renee L. Corpuz, Angela N. Kauwe, Pedro Rendon, Rocio E. Y. Ruano, Amanda A. S. Cardoso, Georgia Gouvi, Elisabeth Fung, Peter Crisp, Anzu Okada, Amanda Choo, Christian Stauffer, Kostas Bourtzis, Sheina B. Sim, Simon W. Baxter, Scott M. Geib

“…Here, we present evidence from classical and modern genetics showing that the black pupae (bp) phenotype in the GUA10 strain of Anastrepha ludens is caused by a large deletion at the ebony locus, removing the gene’s entire coding region. …”
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Current concepts on the use of the partogram to monitor labor progression by Luis Rojas Cedeño, Jorge A. Carvajal

“…However, the modified World Health Organization partogram, which eliminates the latent phase, appears to have advantages over the classic 1994 model, with significantly lower cesarean section rates. …”
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Molecular genetic analysis of Rubinstein–Taybi syndrome in Russian patients by Olga R. Ismagilova, Tagui A. Adyan, Tagui A. Adyan, Tatiana S. Beskorovainaya, Alexander V. Polyakov

“…The specific phenotype of patients enables the so-called “portrait” diagnosis of classical cases of RSTS, followed by the analysis of the CREBBP and EP300 genes, whose association with RSTS has been confirmed. …”
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