Multiple Bone Metastases as the First Manifestation of Hepatocellular Carcinoma in Patient with Noncirrhotic Liver by Soo Ya Bae, Hyun Jung Kim, Hyun Ho Oh, Min Kwan Kwon, Jong Ho Lee, Moon Park, Byeong Seok Sohn

“…This case suggests that HCC should be considered as one of differential diagnoses in patient presenting with multiple bone metastases, even in the absence of liver cirrhosis.…”
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Major Histocompatibility Class II Pathway Is Not Required for the Development of Nonalcoholic Fatty Liver Disease in Mice by Gilles Willemin, Catherine Roger, Armelle Bauduret, Kaori Minehira

“…Secondly we studied the development of carbon-tetra-chloride- (CCl4-) induced hepatic cirrhosis. After the high-fat diet, both groups developed obesity and hepatic steatosis with a similar degree of hepatic inflammation, suggesting no impact of the knockdown of MHC II on high-fat diet-induced inflammation in mice. …”
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Choice of Allograft in Patients Requiring Intestinal Transplantation: A Critical Review by Genevieve Huard, Thomas Schiano, Jang Moon, Kishore Iyer

“…Thus, patients with cirrhosis or advanced fibrosis should receive a combined allograft, while patients with lower grades of liver fibrosis can usually safely undergo ITx. …”
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The dynamics of a delay model of hepatitis B virus infection with logistic hepatocyte growth by Steffen Eikenberry, Sarah Hews, John D. Nagy, Yang Kuang

“…Chronic HBV affects 350 million people and can lead to death through cirrhosis-inducedliver failure or hepatocellular carcinoma. …”
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Dermatological Disorders following Liver Transplantation: An Update by Dipesh Kumar Yadav, Xue li Bai, Tingbo Liang

“…On the other hand, the vast majority of the nonspecific dermatological lesions linked with cirrhosis improve after removal of diseased liver or due to the immunosuppressant used after LT. …”
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Liver Transplantation in Situs Inversus and Portal Vein Thrombosis (First Case Report in Russia) by M. S. Novruzbekov, O. D. Olisov, V. A. Guliaev, K. N. Lutsyk, K. M. Magomedov, B. I. Kazymov

“…A 32 years-old patient with situs inversus, chronic hepatitis B/D-induced liver cirrhosis and portal vein thrombosis had cadaveric liver transplantation, with the transplant reoriented in abdominal cavity 90° clockwise relative to the median plane. …”
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Diagnostic value of optimised real-time sonoelastography in the assessment of liver fibrosis in chronic hepatitis B and C by Katarzyna Kalita, Krzysztof Filipczak, Małgorzata Bieńkiewicz, Wojciech Deroń, Zbigniew Deroń, Anna Piekarska, Anna Płachcińska, Jacek Kuśmierek

“…Sensitivity of both parameters in detection of cirrhosis (F = 4) was equal to 88% and specificity amounted to: for MSF% – 84% and ISR – 86%. …”
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Safety Profile of Liver FibroScan in Patients with Cardiac Pacemakers or Implantable Cardioverter-Defibrillators by Yin Chan, Stephanie Pranke, Farid Rashidi, Shravan Nosib, Lawrence Worobetz

“…None of the subjects had any clinical signs of decompensated congestive heart failure or cirrhosis during the exam. Conclusion. TE with FibroScan can be safely performed in patients with PM or ICD.…”
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Effect of Intervention of Vaccination and Treatment on the Transmission Dynamics of HBV Disease: A Mathematical Model Analysis by Firaol Asfaw Wodajo, Temesgen Tibebu Mekonnen

“…Since people do not give attention, it will develop into cirrhosis and hepatocellular carcinoma that leads to liver transplantation and death. …”
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Short-Term Efficacy of Laparoscopic Treatment for Colorectal Cancer in Patients with Schistosomiasis Japonica by Zhu Yi, Jiang Hong-Gang, Chen Zhi-Heng, Lu Bo-Hao

“…Schistosomiasis is associated with numerous complications such as thrombocytopenia, liver cirrhosis, portal hypertension, and colitis. To the best of our knowledge, the feasibility and outcomes of laparoscopic colorectal surgery in patients with schistosomiasis have not yet been studied. …”
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Plasma α-Glutathione S-Transferase Evaluation in Patients with Acute and Chronic Liver Injury by Jolanta Czuczejko, Celestyna Mila-Kierzenkowska, Karolina Szewczyk-Golec

“…The patients were divided into three groups: group I (acute viral hepatitis B or C), group II (chronic hepatitis B or C), and group III (chronic liver disease or cirrhosis with different etiologies). The concentration of α-GST and the activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were measured in all examined groups. α-GST, ALT, and AST were statistically higher in all patient groups than in the control group. …”
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Virological Mechanisms in the Coinfection between HIV and HCV by Maria Carla Liberto, Emilia Zicca, Grazia Pavia, Angela Quirino, Nadia Marascio, Carlo Torti, Alfredo Focà

“…Several studies demonstrated that HIV worsens the course of HCV infection, increasing the risk of cirrhosis and hepatocellular carcinoma. Also, HCV might increase immunological defects due to HIV and risk of comorbidities. …”
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Characterization of liver, adipose, and fecal microbiome in obese patients with MASLD: links with disease severity and metabolic dysfunction parameters by Katherine J. P. Schwenger, Julia K. Copeland, Yasaman Ghorbani, Lina Chen, Elena M. Comelli, David S. Guttman, Sandra E. Fischer, Timothy D. Jackson, Allan Okrainec, Johane P. Allard

“…Abstract Background Metabolic dysfunction-associated steatotic liver disease (MASLD) encompasses a range of histological findings from the generally benign simple steatosis to steatohepatitis (MASH) which can progress to fibrosis and cirrhosis. Several factors, including the microbiome, may contribute to disease progression. …”
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Cost-effectiveness of Triple Therapy with Telaprevir for Chronic Hepatitis C Virus Patients in Germany by Jona T. Stahmeyer, Svenja Schauer, Siegbert Rossol, Hans Heinrich Wedemeyer, Daniel Wirth, Florence Bianic, Christian Krauth

“…Long-term consequences are the development of liver cirrhosis and hepatocellular carcinoma. The introduction of first generation protease inhibitors has significantly improved the treatment of hepatitis C genotype 1 patients. …”
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Computer-tomography features of hemodynamics in hepatocellular carcinoma foci depend on the stage of histological differentiation by U. N. Tumanova, N. I. Yashina, Ye. A. Dubova, G. G. Karmazanovsky, A. I. Schegolev

“…The study was based on the clinical and morphological data of 19 patients (12 men and 7 women, aged 18–72 years), with hepatocellular carcinoma (HCC) without coexistent liver cirrhosis. At a preoperative stage all patients underwent helical CT with bolus contrast enhancement (four phases study), with estimation of arterial and venous density gain ofthe lesion and CT-vascularization index. …”
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Differential expression of “A Disintegrin and Metalloproteinase 10” in hepatocellular carcinoma and the noncancerous hepatic tissues: Contribution to HCV-promoted hepatocarcinogene... by Amal Abd El Hafez, Basem H. Elesawy, Heba S. E. I. Hany

“…HCCs were statistically compared in relation with gender, age, cirrhosis, hepatitis C virus (HCV) status, alpha-fetoprotein (AFP) serum level, tumor size, multiplicity, encapsulation/invasion, grade, histological pattern and variant, mitosis, necrosis, vascular emboli, portal thrombosis, stage, recurrence, and mortality. …”
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Glycogen Storage Disease Type IX in a 6-year-old Male: A Case Report by Shahab Noorian, Hossein Moravej, Zhila Afshar, Afagh Hassanzadeh Rad, Setila Dalili

“…Ongoing research into the molecular mechanisms of GSDs offers hope for more effective treatments, especially for GSD type IX, where individualized care can prevent complications like liver cirrhosis and promote better quality of life.…”
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Pegilated interferon α2а in treatment of chronic hepatitis C by P. O. Bogomolov, S. V. Koblov, A. O. Buyeverov, M. V. Matsiyevich, O. S. Kuzmina, N. A. Barsukova, N. V. Dubinina

“…Prior to therapy onset needle liver biopsy was carried out in 88,3% of patients, subsequently liver cirrhosis was diagnosed in 77 patients. In 227 of patients the 1-st HCV genotype was revealed, 2nd genotype – in 24, 3rd genotype – in 41cases.Results. …”
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Metastatic Hepatocellular Carcinoma in a Patient with Crohn’s Disease Treated with Azathioprine and Infliximab: A Case Report and Literature Review by Kyle J. Fortinsky, Ali Alali, Khursheed Jeejeebhoy, Sandra Fischer, Morris Sherman, Scott Fung

“…Hepatocellular carcinoma most commonly occurs in patients with underlying liver disease or cirrhosis. We describe a case of hepatocellular carcinoma in a 34-year-old man with Crohn’s disease treated with azathioprine and infliximab. …”
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Autoantibody Response to Murine Double Minute 2 Protein in Immunodiagnosis of Hepatocellular Carcinoma by Mei Liu, Su-jun Zheng, Yu Chen, Ning Li, Peng-fei Ren, Li-ping Dai, Zhong-ping Duan, Jian-Ying Zhang

“…The prevalence of autoantibodies against MDM2 was significantly higher than that in liver cirrhosis (LC), chronic hepatitis (CH), and normal human sera (NHS). …”
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