Gamma-Glutamyl Transpeptidase-to-Platelet Ratio Predicts Significant Liver Fibrosis of Chronic Hepatitis B Patients in China by Tianyi Ren, Huan Wang, Ruihong Wu, Junqi Niu

“…The AUROCs of GPR and Fib-4 for fibrosis (0.77 versus 0.75, P=0.14), significant fibrosis (0.70 versus 0.70, P=0.22), extensive fibrosis (0.71 versus 0.68, P=0.13), and cirrhosis (0.64 versus 0.67, P=0.24) were comparable. …”
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Spleen and Liver Stiffness Evaluation by ARFI Imaging: A Reliable Tool for a Short-Term Monitoring of Portal Hypertension? by Andreas Binzberger, Mark Hänle, Matthias Pfahler, Wolfgang Kratzer, Thomas Seufferlein, Eugen Zizer

“…We prospectively assessed portal hypertension by HVPG and corresponding elastography of the liver and spleen in 31 patients with liver cirrhosis and an indication for primary prophylaxis by non-cardio selective beta-blockers. …”
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OSAS-Related Inflammatory Mechanisms of Liver Injury in Nonalcoholic Fatty Liver Disease by Elena Paschetta, Paola Belci, Anna Alisi, Daniela Liccardo, Renato Cutrera, Giovanni Musso, Valerio Nobili

“…Several studies suggest that the chronic intermittent hypoxia (CIH) of OSAS patients may per se trigger liver injury, inflammation, and fibrogenesis, promoting NAFLD development and the progression from steatosis to steatohepatitis, cirrhosis, and hepatocellular carcinoma. In NAFLD patients, liver disease may be caused by hypoxia both indirectly by promoting inflammation and insulin resistance and directly by enhancing proinflammatory cytokine production and metabolic dysregulation in liver cells. …”
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Antiphospholipid Syndrome as a Cause of Recurrent Portal Vein Thrombosis in a Man with a Medical History of other Thrombosis by R. G. Sayfutdinov, R. R. Saifutdinov, R. R. Akhunova, T. V. Saifutdinova, G. R. Absalyamova, T. V. Dvoryankina, G. R. Akhunova

“…For several years, the patient had the diagnosis of cirrhosis based on the presence of signs of portal hypertension. …”
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Association between Serum Albumin Concentration and Ketosis Risk in Hospitalized Individuals with Type 2 Diabetes Mellitus by Po-Chung Cheng, Shang-Ren Hsu, Yun-Chung Cheng

“…Individuals without measurement of serum albumin, urine ketone, or hemoglobin A1C, or harboring active infection, myocardial infarction, cerebrovascular event, cirrhosis, malignancy, or overt proteinuria were excluded. …”
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Ligation of Left Renal Vein for Spontaneous Splenorenal Shunt to Prevent Portal Hypoperfusion after Orthotopic Liver Transplantation by Lampros Kousoulas, Kristina Imeen Ringe, Michael Winkler, Frank Lehner, Nicolas Richter, Juergen Klempnauer, Fabian Helfritz

“…We report a case of recovered portal flow by ligation of the left renal vein on the first postoperative day after orthotopic liver transplantation of a 54-year-old female with alcoholic liver cirrhosis, chronic kidney failure, and spontaneous splenorenal shunt. …”
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Disulfiram Induced Psychosis: A Case Report by D. R. Survilaitė, R. Žemaitytė

“…The drug should be used with caution in people with a history of heart disease, diabetes mellitus, hypothyroidism, cerebral damage, nephritis, liver cirrhosis, epilepsy. Caution is recommended for patients who use benzodiazepines, some antibiotics, anticoagulants, tricyclic antidepressants. …”
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Rare forms of nonalcoholic fatty liver disease: hereditary lysosomal acid lipase deficiency by M. V. Mayevskaya, V. T. Ivashkin, M. S. Zharkova, T. P. Nekrasova, G. I. Ayusheva, R. V. Maslennikov

“…Early detection of DLAL patients and adequate treatment can prevent development of the liver cirrhosis associated to this disease, as well as cardio-vascular complications.…”
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Infusion therapy for chronic liver diseases by I. A. Kurkina, M. V. Mayevskaya, I. N. Tikhonov, V. N. Zozulya, V. I. Leschenko

“…Application of basic group infusion solutions along with complex anti-hypoxia agents helps to correct water and electrolyte imbalance as well as disorders of acid-base state, carry out body detoxication, normalize blood pressure, treat edema and ascites syndrome, protein-energy malnutrition, prevent renal value and other complications in liver cirrhosis patients. Comprehensive treatment of liver diseases includes application of modern infusion agents (anti-hypoxia/anti-oxidation) containing pharmacologically active metabolic substances that include succinate-containing drugs developed on the basis of succinic acid and its salts. …”
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Hepatorenal Syndrome: Outcome of Response to Therapy and Predictors of Survival by Jan Heidemann, Christoph Bartels, Christoph Berssenbrügge, Hartmut Schmidt, Tobias Meister

“…Treatment of hepatorenal syndrome (HRS) in patients with liver cirrhosis is still challenging and characterized by a very high mortality. …”
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Validation and Refinement of the Baveno VI Criteria for Ruling Out High-Risk Varices by Hong Zhou, Han Hu, Maoyong Tian, Jun Chu, Caiyun Tian, Yanqing Yang, Shide Lin

“…In the past decade, numerous studies have evaluated the roles of noninvasive methods for diagnosing or excluding varices and high-risk varices in patients with liver cirrhosis. The Baveno VI criteria recommend the use of a simple algorithm based on a liver stiffness measurement<20 kPa through transient elastography and a platelet count>150×109/L for ruling out high-risk varices in patients with compensated advanced chronic liver disease. …”
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Association between Nonalcoholic Fatty Liver Disease and Endocrinopathies: Clinical Implications by Ana-Maria Singeap, Carol Stanciu, Laura Huiban, Cristina Maria Muzica, Tudor Cuciureanu, Irina Girleanu, Stefan Chiriac, Sebastian Zenovia, Robert Nastasa, Catalin Sfarti, Camelia Cojocariu, Anca Trifan

“…Its potential for evolution towards liver cirrhosis and hepatocellular carcinoma, as well as associations with extrahepatic manifestations, represents a double burden for patients and physicians alike. …”
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Hepatocellular Carcinoma: Current Management and Future Development—Improved Outcomes with Surgical Resection by Yoji Kishi, Kiyoshi Hasegawa, Yasuhiko Sugawara, Norihiro Kokudo

“…Although repeat hepatectomy may prolong survival, the suitability may be limited due to multiple tumor recurrence or background liver cirrhosis. Multimodality approaches combining other local ablation or systemic therapy may help improve the prognosis. …”
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Antifibrotic Effect of Combination of Nilotinib and Stem Cell-Conditioned Media on CCl4-Induced Liver Fibrosis by Gamal Shiha, Ahmed Nabil, Ahmed Lotfy, Reham Soliman, Ayman A. Hassan, Islam S. Ali, Doaa F. Gad, Faten Zahran

“…Advanced liver fibrosis leads to cirrhosis and liver failure. Nilotinib is a second-generation tyrosine kinase inhibitor, which showed antifibrotic efficacy. …”
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Characterization of patients with chronic liver disease of alcoholic etiology by Doppler ultrasound. Cienfuegos, 2020 by Masleidy Valladares Valle, Lariagna Moya Cardoso, Dianarelys Villafuerte Delgado, Rubén Daniel Fernández Azpiri, Liam Lain Pérez Valladares, Claudia Vasallo López

“…<p><strong>Background</strong>: chronic liver diseases are frequent diseases worldwide. Liver cirrhosis, whose most frequent etiology is alcoholism, represents the end of chronic and progressive diffuse liver lesions.…”
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Iron metabolism in a mouse model of hepatocellular carcinoma by Dilay Yilmaz, Umesh Tharehalli, Rossana Paganoni, Paul Knoop, Andreas Gruber, Yuexin Chen, Rui Dong, Frank Leithäuser, Thomas Seufferlein, Kerstin Leopold, André Lechel, Maja Vujić Spasić

“…To investigate iron metabolism during liver carcinogenesis, we employed a model of chronic carbon tetrachloride injections in liver-specific p53-deficient mice to induce liver fibrosis, cirrhosis and subsequent carcinogenesis. A transcriptome analysis of liver carcinoma was employed to identify p53-dependent gene expression signatures with subsequent in-depth analysis of iron metabolic parameters being conducted locally within liver cancers and at systemic levels. …”
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Nonalcoholic Fatty Liver Disease-Related Chronic Kidney Disease by Camelia Cojocariu, Ana-Maria Singeap, Irina Girleanu, Stefan Chiriac, Cristina M. Muzica, Catalin Victor Sfarti, Tudor Cuciureanu, Laura Huiban, Carol Stanciu, Anca Trifan

“…The proportion of patients with liver cirrhosis and those with hepatocellular carcinoma due to nonalcoholic liver disease on the liver transplant waiting list has increased in the last years. …”
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Hepatitis C pada Anak by Yusri Dianne Jurnalis, Yorva Sayoeti, Adria Russelly

“…Acute HCV infection may end up with cirrhosis and hepatocellular carcinoma after the third decade (around 20%), due to a slower progression of HCV infection of hepatitis B virus infection. …”
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Clostridium Difficile and COVID-19: Novel Risk Factors for Acute Portal Vein Thrombosis by Venkata Ram Pradeep Rokkam, Gurusaravanan Kutti Sridharan, Rathnamitreyee Vegunta, Radhakrishna Vegunta, Umesha Boregowda, Babu P. Mohan

“…We report a case of an elderly female with a recent diagnosis of COVID-19 and no prior history of cirrhosis or malignancy who presented with diarrhea due to clostridium difficile infection. …”
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Diagnostic Utility of Serum Ascites Lipid and Protein Gradients in Differentiation of Ascites by Mukhyaprana Prabhu, Rahul Sai Gangula, Weena Stanley

“…The study included 60 patients with ascites of different etiologies (liver cirrhosis, tubercular peritonitis, and malignant ascites). …”
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