Nonalcoholic Fatty Liver Disease: A Clinical Approach and Review by Maitreyi Raman, Johane Allard

“…The spectrum of disease is variable, ranging from simple steatosis with benign prognosis, to non-alcoholic steatohepatitis and cirrhosis, conferring increase in morbidity and mortality. …”
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Endogenous endophthalmitis associated with autoimmune hepatitis: case report by D.F. Belov, V.G. Korotkov, P.A. Nikitin, I.V. Terekhova, Ya.S. Konenkova

“…After canceling steroids, AIH progressed to cirrhosis. Here, the development of EE was probably associated with secondary immunodeficiency in the setting of AIH. …”
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Autoimmune Hepatitis in Children: The Current State of the Problem by G. V. Volynets, A. I. Khavkin, T. A. Skvortsova, V. V. Matkash

“…In cases of refractoriness to therapy and the disease progression to liver cirrhosis and its decompensation, liver transplantation is justified. …”
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Comprehensive Analysis of Competing Endogenous RNA Network Focusing on Long Noncoding RNA Involved in Cirrhotic Hepatocellular Carcinoma by Yuli Zhang, Dinggui Chen, Miaomiao Yang, Xianfeng Qian, Chunmei Long, Zhongwei Zheng

“…A total of 74 lncRNAs, 36 intersection miRNAs, and 949 mRNAs were differentially expressed in cirrhotic HCC samples compared with cirrhosis samples. We constructed a ceRNA network, including 47 lncRNAs, 35 miRNAs, and 168 mRNAs. …”
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Two-Dimensional Shear-Wave Elastography: Accuracy in Liver Fibrosis Staging Using Magnetic Resonance Elastography as the Reference Standard by Puwitch Charoenchue, Jiraporn Khorana, Taned Chitapanarux, Nakarin Inmutto, Wittanee Na Chiangmai, Amonlaya Amantakul, Suwalee Pojchamarnwiputh, Apichat Tantraworasin

“…Increasing the threshold to 8.0 kPa improved specificity to 91.8% while maintaining a sensitivity of 86.4% and achieving an AUROC of 0.89. For cirrhosis, a cut-off of 11.0 kPa achieved 100% sensitivity and 96.9% specificity. …”
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DNA Damage Sensor γ-H2AX Is Increased in Preneoplastic Lesions of Hepatocellular Carcinoma by Yasunobu Matsuda, Toshifumi Wakai, Masayuki Kubota, Mami Osawa, Masaaki Takamura, Satoshi Yamagiwa, Yutaka Aoyagi, Ayumi Sanpei, Shun Fujimaki

“…Moreover, γ-H2AX was significantly increased in nontumorous tissues of HCC as compared with liver cirrhosis without HCC (62.5±24.7%, from 5.1 to 96.0%, P<0.005). …”
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From the Cytoplasm into the Nucleus—Hepatitis B Virus Travel and Genome Repair by Johan Ringlander, Gustaf E. Rydell, Michael Kann

“…HBV is part of the hepadnaviridae family and one of the primary causes of acute and chronic liver infections, leading to conditions such as cirrhosis and hepatocellular carcinoma (HCC). Understanding the intracellular transport and genome repair mechanisms of HBV is crucial for developing new drugs, which—in combination with immune modulators—may contribute to potential cures. …”
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Research Progress on the Mechanism of Acupuncture Treatment for Nonalcoholic Fatty Liver Disease by Bai Li, Li Fang

“…Nonalcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease worldwide, ranging from simple steatosis and nonalcoholic steatohepatitis to fibrosis, cirrhosis, and hepatocellular carcinoma. Acupuncture is a long-established treatment in traditional Chinese medicine. …”
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Ursodeoxycholic Acid and Atorvastatin in the Treatment of Nonalcoholic Steatohepatitis by Murat Kiyici, Macit Gulten, Selim Gurel, Selim Giray Nak, Enver Dolar, Gursel Savci, Saduman Balaban Adim, Omer Yerci, Faruk Memik

“…BACKGROUND/AIMS: Nonalcoholic steatohepatitis (NASH) is a serious disorder with the potential to gradually progress to cirrhosis. It is generally associated with obesity, diabetes and hyperlipidemia. …”
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The Many Difficulties and Subtleties in the Cognitive Assessment of Chronic Hepatitis C Infection by Jefferson Abrantes, Daniel Simplicio Torres, Carlos Eduardo Brandão – Mello

“…Often, patients with hepatitis C virus (HCV) complain of cognitive impairment even before the development of hepatic cirrhosis, which they described as “brain fog.” Several studies have proposed a link between chronic HCV infection and the development of cognitive alterations, but the inclusion of confounding factors in their samples significantly limits the analysis of the results. …”
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Cortical laminar necrosis triggered by hepatic encephalopathy and post-traumatic subarachnoid hemorrhage: Case report by Inas AL CHARE, Mickaël BONNAN

“…We report a 56-year-old woman with liver cirrhosis who presented with prolonged floor station, reduced alertness and left hemiplegia. …”
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Diagnostics of hepatocellular cancer: state-of-the-art by T. Yu. Danzanova, G. T. Sinyukova, P. I. Lepedatu

“…The radiology is described at accompanying cirrhosis, difficulty of small HCC detection. Radiological differential diagnostics of HCC should be carried out with dysplastic nodules. …”
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Role of TIPS in Improving Survival of Patients with Decompensated Liver Disease by Sundeep J. Punamiya, Deepak N. Amarapurkar

“…Liver cirrhosis is associated with higher morbidity and reduced survival with appearance of portal hypertension and resultant decompensation. …”
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Drug Therapy for Non-Alcoholic Steatohepatitis-Induced Liver Fibrosis by D. V. Garbuzenko

“…Given a lack of approved antifibrotic therapies in NASH, several drugs have nevertheless demonstrated an adequate efficacy and safety in phase 3 clinical trials, also in compensated cirrhosis, which allows their practical validation in phase 4.Conclusion. …”
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Successful Treatment of Hepatoportal Arteriovenous Fistula by Transcatheter Embolization with Steel Coils by Taralyn D Picton, Lindsay Machan, Jennifer Davis, Hugh J Freeman, Urs P Steinbrecher

“…Portal hypertension is most commonly caused by increased intrahepatic resistance as a result of cirrhosis, but can also occur as a result of abnormally high portal bloodflow. …”
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Mechanisms of Alcohol-Induced Endoplasmic Reticulum Stress and Organ Injuries by Cheng Ji

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Update on Ppar𝜸 and Nonalcoholic Fatty Liver Disease by Gene P. Ables

“…Uninterrupted progression of hepatic lipid accumulation often leads to fatty liver disease and eventually cirrhosis. Insulin resistance is one of the characteristics of type 2 diabetes. …”
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Sport-Related Portal Vein Thrombosis: An Unusual Complication by Igor Dumic, Nikola Tankosic, Milica Stojkovic Lalosevic, Tamara Alempijevic

“…Portal vein thrombosis (PVT) is an uncommon condition usually associated with hypercoagulable states or liver cirrhosis. PVT due to sports-related injuries is rarely reported and, to the best of our knowledge, only two cases have been reported thus far. …”
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Genotype 3 is linked to worse liver disease progression in hepatitis C patients even after SVR following DAA therapy by Xiping Ran, Xiping Ran, Yang Xu, Ying Wang, Cheng Zeng, Chen Gong, Ni Wang, Dachuan Cai, Dachuan Cai

“…The clinical outcome was overall liver disease progression (OLDP), defined as newly diagnosed compensated liver cirrhosis, decompensated liver cirrhosis, or hepatocellular carcinoma. …”
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Survival analysis of patients with hepatocellular carcinoma based on the ratio of platelet count to spleen diameter by Huiwen Yan, Dongdong Zhou, Dongdong Zhou, Xiaoli Liu, Peng Wang, Tingting Jiang, Zhiyun Yang

“…BackgroundIn China, 80% of Hepatocellular Carcinoma (HCC) is associated with cirrhosis. Portal hypertension, the most common outcome of cirrhosis progression, has a high incidence. …”
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