Showing 1 - 9 results of 9 for search '"cilium"', query time: 0.04s Refine Results
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    Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo. by Ashish Kumar Maurya, Jin Ben, Zhonghua Zhao, Raymond Teck Ho Lee, Weixin Niah, Ashley Shu Mei Ng, Audrey Iyu, Weimiao Yu, Stone Elworthy, Fredericus J M van Eeden, Philip William Ingham

    Published 2013-01-01
    “…While this implies a functional conservation of Cos2 and Kif7 between flies and vertebrates, the association of Kif7 with the primary cilium, an organelle absent from most Drosophila cells, suggests their mechanisms of action may have diverged. …”
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    Loss of Kat2b impairs intraflagellar transport and the Hedgehog signaling pathway in primary cilia by Jae Hee Jun, Hwayeon Cha, Je Yeong Ko, Ho-Shik Kim, Kyung Hyun Yoo, Jong Hoon Park

    Published 2025-01-01
    “…Kat2b, which mainly regulates transcription as a p300/CBP associated factor, is localized to the cytosol, centrosome, and cilium basal body. In addition, basal Kat2b expression gradually increased during ciliogenesis. …”
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    On the Origin of the Nervous System Based on Studying Sensillae in Acoel Turbellarians (Acoela) by Ya.I. Zabotin, A.I. Golubev

    Published 2017-09-01
    “…The sensitive part bears one cilium with a thin transversely striated spindle-shaped rootlet; the basal part contains a bundle of myofibrils. …”
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    Prx1-Expressing Progenitor Primary Cilia Mediate Bone Formation in response to Mechanical Loading in Mice by Emily R. Moore, Julia C. Chen, Christopher R. Jacobs

    Published 2019-01-01
    “…Although Prx1-driven primary cilium disruption did not affect osteoblast recruitment to the bone surface, the relative mineral apposition and bone formation rates were decreased by 53% and 34%, respectively. …”
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    Temporal ablation of the ciliary protein IFT88 alters normal brainwave patterns by Matthew R. Strobel, Yuxin Zhou, Liyan Qiu, Aldebaran M. Hofer, Xuanmao Chen

    Published 2025-01-01
    “…Abstract The primary cilium is a hair-like organelle that hosts molecular machinery for various developmental and homeostatic signaling pathways. …”
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    Comparison of CRISPR-Cas13b RNA base editing approaches for USH2A-associated inherited retinal degeneration by Lewis E. Fry, Lauren Major, Ahmed Salman, Lucy A. McDermott, Jun Yang, Andrew J. King, Michelle E. McClements, Robert E. MacLaren

    Published 2025-02-01
    “…In mice injected with PspCas13b constructs, usherin protein was successfully restored and correctly localized to the connecting cilium following RNA editing. These results support the development of transcriptome targeting gene editing therapies for retinal disease.…”
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