Alpha-1 Antitrypsin as a Regulatory Protease Inhibitor Modulating Inflammation and Shaping the Tumor Microenvironment in Cancer by Siyu Xiang, Liu Yang, Yun He, Feng Ding, Shuangying Qiao, Zonghua Su, Zheng Chen, Aiping Lu, Fangfei Li

“…AAT restrains the pulmonary matrix from enzymatic degradation, and a deficiency in AAT leads to inflammatory tissue damage in the lungs, resulting in chronic obstructive pulmonary disease. Due to the crucial biological function of AAT, the emerging research interest in this protein has shifted to its role in cancer-associated inflammation and the dynamics of the tumor microenvironment. …”
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Catlet scoring system as a new predictor for in-stent restenosis in patients with chronic coronary artery disease undergoing percutaneous coronary intervention with drug-eluting st... by Juan Wang, Mingchao Zhang, Weipeng Gan, Mingxing Xu, JiaYan Zhou, Lingfei Yang, Yongsheng Ke

“…Patients in the ISR group had significantly the history of chronic obstructive pulmonary disease(COPD), adverse lesion characteristic, higher Catlet score compared with patients in the non-ISR group.The CatLet score was capable of predicting in-stent restenosis after adjustment for risk factors; The Multivariable-adjusted model showed good calibration and good discrimination (area under ROC curve = 0.7164) for ISR. …”
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Global, regional, and national burden of young COPD, 1990–2021, with forecasts to 2050: a systematic analysis for the global burden of disease study 2021 by Yi Zhu, Tao Shen, Ruixin Guo, Ke Liu, Xiyu Cao, Xiuli Yang, Chuantao Zhang

“…Abstract Background Young chronic obstructive pulmonary disease (COPD) refers to people with COPD between the ages of 20 and 50 years. …”
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Association between vitamin D levels and preserved ratio impaired spirometry: an investigation of mediating roles of systemic inflammation and metabolic indicators by Tong Lin, Shanshan Huang, Fen Zhou, Xingkai Shen, Haiyan Mao

“…BackgroundPreserved ratio impaired spirometry (PRISm) represents an abnormal lung function state distinct from traditional chronic obstructive pulmonary disease, characterized by unique clinical and epidemiological features. …”
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Phytochemicals of Vitis vinifera L. var. King Ruby protect mice from benzo(a)pyrene-induced lung injury by Gehad S. Ahmedy, Hend M. Selim, Mona El-Aasr, Souzan M. Ibrahim, Suzy A. El-Sherbeni

“…Abstract The world’s concern about smoking hazards, chronic obstructive pulmonary disease (COPD) and lung cancer was the motivation to investigate plants as a source of new drugs with lung protective effect. …”
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Exposure to Air Pollution Exacerbates Inflammation in Rats with Preexisting COPD by Jing Wang, Ya Li, Peng Zhao, Yange Tian, Xuefang Liu, Huihui He, Rui Jia, Brian G. Oliver, Jiansheng Li

“…Particulate matter with an aerodynamic diameter equal or less than 2.5 micrometers (PM2.5) is associated with the development of chronic obstructive pulmonary disease (COPD). The mechanisms by which PM2.5 accelerates disease progression in COPD are poorly understood. …”
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Distribution of fungal agents in the respiratory system of patients with underlying lung diseases; molecular identification and antifungal susceptibility profiles by Parviz Hassanpour, Seyed Jamal Hashemi, Sanam Nami, Roshanak Daie Ghazvini, Behrouz Naghili Hokmabadi, Abbas Rahimi Foroushani, Kazem Ahmadikia, Zahra Ramezanalipour, Saeid Firouzi Abriz

“…Candida albicans and Aspergillus flavus were the most common yeast and mold species. Chronic obstructive pulmonary disease (COPD) had the highest rate of colonization with fungal agents (47/114, 41%). …”
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Turning green: the impact of changing to more eco-friendly respiratory healthcare – a carbon and cost analysis of Dutch prescription data by Evelyn A Brakema, johan Kooistra, Niels Chavannes, Paul Hagedoorn, Pieter ten Have, Peter van Hal, Iris Wichers, Pauline de Heer, Hans C Ossebaard

“…First, we calculated the number of patients with chronic obstructive pulmonary disease (COPD) and asthma that were using inhalation medication (2020). …”
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Suitability of Measures of Pharmacy-Based Medication Adherence for Routine Clinical Use Among Patients with Chronic Diseases: A Systematic Review by Jannah W, Khoiry QA, Alfian SD, Abdulah R

“…This review included English studies on assessing medication adherence for hypertension, hyperlipidemia, asthma, chronic obstructive pulmonary disease, and diabetes, using pharmacy databases and providing full-text access. …”
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Muscle contractile properties and perceived fatigue in the general and diseased population by Isa H. Mast, Neeltje A. E. Allard, Dominique tenHaaf, Anouk A. F. Stoffels, Lando Janssen, Hieronymus W. H. vanHees, Silvie Timmers, Bregina T. P. Hijmans‐Kersten, Maria T. E. Hopman, Laurien M. Buffart

“…We pooled data on perceived fatigue, physical fitness, and contractile properties from six studies, including a control group (n = 90), cancer survivors (n = 27), patients with chronic obstructive pulmonary disease (COPD; n = 16), chronic myeloid leukemia (CML; n = 20), and statin users (n = 64). …”
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The Impact of COVID-19 on Hospitalised COPD Exacerbations in Malta by Yvette Farrugia, Bernard Paul Spiteri Meilak, Neil Grech, Rachelle Asciak, Liberato Camilleri, Stephen Montefort, Christopher Zammit

“…This study is aimed at investigating a significant difference between the number of acute exacerbations of chronic obstructive pulmonary disease (AECOPD) admissions and their inpatient outcome at Mater Dei Hospital during the COVID-19 pandemic when compared to the same period in 2019. …”
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MANAGEMENT OF MARGINAL ULCERS IN OBESE PATIENTS AFTER LAPAROSCOPIC GASTRIC BYPASS by Olexander Ioffe, Victor Nevmerzhytskyi

“…According to logistic regression, taking non-steroidal anti-inflammatory drugs OR = 3.62 (95%CI 1.04-12.6, p<0.001), diabetes type 2 OR = 2.62 (95%CI 0.75-9.09, p<0.001), chronic obstructive pulmonary diseases OR=2.25 (95%CI 1.19-4.28, p<0.001), affect the occurrence marginal ulcers. …”
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Short-acting beta agonist, antibiotics, oral corticosteroid and association with mortality and cardiopulmonary events in patients with COPD: a retrospective cohort study in Alberta... by Mohit Bhutani, Irvin Mayers, Arsh Randhawa, Manisha Talukdar, Suzanne McMullen, Phongsack Manivong, Aaron Gelfand

“…Objective The purpose of the study was to examine the association between short-acting beta agonist (SABA), antibiotic and oral corticosteroid (OCS) use and mortality and cardiopulmonary outcomes in chronic obstructive pulmonary disease (COPD).Design Retrospective cohort study using administrative health data from 1 April 2011 to 31 March 2020.Setting Alberta, Canada.Participants Patients ≥35 years old with COPD were identified using diagnostic codes.Primary and secondary outcome measures Patient characteristics included age, sex, geographical zone and comorbidities (as defined by the Charlson Comorbidity Index). …”
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Retrospective cross-sectional study on bronchiectasis in adult Aboriginal Australians: disease characteristics and comparison with ethnically diverse global bronchiectasis registry... by Timothy Howarth, Subash Heraganahally, Claire Gibbs, Lata Jayaram, Asanga Abeyaratne, Shiidheshwar J Ravichandran, Davaadorj Erdenebayar, Winnie Chen, Hubertus Jersmann

“…Smoking rates were higher at 85% compared with other registry cohorts (22–46%) as was the prevalence of comorbidities (97%): cardiovascular diseases (73%), diabetes mellitus (50%) and chronic obstructive pulmonary disease (83%) compared with other registry cohorts (4–32%; 6–14%; and 14–37%, respectively). …”
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Non-communicable airway disease and air pollution in three African Countries: Benin, Cameroon and The Gambia by B. Awokola, H. Lawin, O. Johnson, A. Humphrey, D. Nzogo, L. Zubar, G. Okello, S. Semple, E. Awokola, G. Amusa, N. Mohammed, C. Jewell, A. Erhart, K. Mortimer, G. Devereux, B.H. Mbatchou-Ngahane

“…A diagnosis of asthma was present in 74.0%; 16.3% had chronic obstructive pulmonary disease and 4.1% had chronic bronchitis. …”
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Outcome of Pleural Empyema Treated With Video-Assisted Thoracoscopic Surgery in Patients With Severe Co-Morbidities: An Observational Study by Vu HA, Nguyen NV, Le TD, Nguyen ST, Viet Le A, The Vu A, Van Nguyen B, Van Nguyen B, Thanh Quan N, An NV, Duc Nghiem T

“…Some comorbidities contained chronic obstructive pulmonary disease (COPD) (25.0%), spontaneous esophageal perforation (16.7%), liver cancer, cirrhosis, esophageal cancer, end-stage renal failure – chronic dialysis (8.7%). …”
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Germline variants of the genes involved in NF-kB activation are associated with the risk of COPD and lung cancer development by Baranasic Jurica, Niazi Yasmeen, Chattopadhyay Subhayan, Rumora Lada, Ćorak Lorna, Dugac Andrea Vukić, Jakopović Marko, Samaržija Miroslav, Försti Asta, Knežević Jelena

“…Chronic obstructive pulmonary disease (COPD) and lung cancer (LC) are closely related diseases associated with smoking history and dysregulated immune response. …”
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Is longer really better? Results of a retrospective real-life cohort study evaluating the benefit of adding a weekly educational session to a traditional 8-week home-based pulmonar... by Cécile Chenivesse, Olivier Le Rouzic, Jean-Marie Grosbois, Sarah Gephine, Sophie Peres

“…Objectives To evaluate the short-term and long-term benefits of adding a weekly educational session to a traditional 8-week home-based pulmonary rehabilitation (PR) programme in people with chronic obstructive pulmonary disease (COPD). Primary hypothesis was that 8 home-based supervised sessions will be equivalent to 16 home-based supervised sessions at both short- and long-term after PR.Design Retrospective cohort study conducted on prospectively collected real-life data, from January 2010 to December 2021.Setting FormAction Santé, Pérenchies France.Participants Eligible individuals were aged &gt;18 years with a diagnosis of COPD and referred to the home-based PR programme by their respiratory physician. …”
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The availability of drugs for stable COPD treatment in China: a cross-sectional survey by Dongru Du, Xueru Hu, Qiunan Zuo, Dan Xu, Tao Zhu, Tao Fan, Jiao Yang, Weiguo Xu, Hailong Wei, Kangzhuo Baima, Ying Zhang, Yanhui Gu, Lei Chen, Fengming Luo, Yongchun Shen, Fuqiang Wen

“…Abstract This survey aimed to investigate the availability of drugs for stable chronic obstructive pulmonary disease (COPD) treatment in Chinese hospitals and to determine whether drug availability significantly varied among hospitals with different characteristics. …”
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Screening of Anti-Inflammatory Components of Qin Jin Hua Tan Tang by a Multivariate Statistical Analysis Approach for Spectrum-Effect Relationships by Feipeng Duan, Yisheng Li, Meizhen Zhao, Tianyong Hu, Xinquan Pan, Yue Feng, Fang Ma, Shuqi Qiu, Yiqing Zheng

“…Qing Jin Hua Tan Tang (QJHTT) exerts therapeutic effects in patients with chronic obstructive pulmonary disease (COPD) by alleviating inflammation. …”
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