Adeno-Associated virus 8 delivers an immunomodulatory peptide to mouse liver more efficiently than to rat liver. by Yuqing Wang, Ayrea Hurley, Marco De Giorgi, Mark R Tanner, Rong-Chi Hu, Michael W Pennington, William R Lagor, Christine Beeton

“…However, like most biologics, ShK and its analogs require injections for their delivery, and repeated injections reduce patient compliance during the treatment of chronic diseases. We hypothesized that inducing the expression of an ShK analog by hepatocytes would remove the requirement for frequent injections and lead to a sustained level of Kv1.3 blocker in the circulation. …”
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Deliberate self-poisoning and suicidality: A qualitative analysis of the factors that influence repetitive suicidal behavior by Kelečević Igor M., Vejnović Ana-Marija T., Mijatović-Jovin Vesna M.

“…Suicidal individuals often have psychiatric comorbidities, most frequently mental and behavioral disorders due to psychoactive substance use and personality disorders. Chronic diseases are also factors that can lead to suicide attempts. …”
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Estimation of Cardiovascular Risk in Patients with Type 2 Diabetes by Belkis Vicente Sánchez, Ernesto Vicente Peña, Miriam Costa Cruz

“…Variables studied were: age, sex, body mass index, nutritional assessment, blood pressure, toxic habits, associated chronic diseases, blood levels of glucose, lipids (total cholesterol and triglycerides) and microalbuminuria. …”
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Integrating mandatory occupational health practice and workplace health promotion programs to reduce the high burden of work-related diseases by Francesco CHIRICO, Angelo SACCO, Nicola MAGNAVITA

“…Long working hours have been linked to an increased risk of ischemic heart disease and stroke. Chronic diseases such as diabetes and cardiovascular disease diminish individuals' quality of life and have negative employment consequences. …”
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Partially unraveling mechanistic underpinning and weight loss effects of time-restricted eating across diverse adult populations: A systematic review and meta-analyses of prospecti... by Duc Tran Quang, Nguyen Di Khanh, Linh Le Cu, Huyen Nguyen Thi Hoa, Chi Vu Thi Quynh, Quang Phan Ngoc, Thuy Bui Thi

“…The effectiveness of the TRE was found to vary across health conditions, with modest weight loss observed in healthy individuals (pooled effect size -1.04 Kg, 95% CI: -1.42 to -0.65) and more significant weight reduction seen in participants with chronic diseases (pooled effect size -3.33 Kg, 95% CI: -5.05 to -1.62) and overweight/obesity (pooled effect size -4.21 Kg, 95% CI: -5.23 to -3.10). …”
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Corpus callosotomy for treatment of pediatric epilepsy: two clinical cases and a literature review by R. Matonytė, S. Ročka, J. Grikinienė

“… Epilepsy is one of the most common chronic diseases in children and it affects approximately 6.1 per 1000 children in Lithuania as of 2018 data. …”
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Enfermedad pulmonar obstructiva crónica by Reinaldo Pino Blanco, Orestes Álvarez Fernández, Juan De Dios Rivero Berovides

“…</p><p>Chronic Obstructive Pulmonary Disease has become one of the most frequently treated chronic diseases in primary health care. High rates of morbidity and mortality are worldwide related to this disease. …”
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Matrix Metalloproteinase-9 is associated with tumor microenvironment remodeling of bladder cancer by Fang Fang, Tiange Wu, Mengxue Wang, Wenchao Li, Zonghao You, Ming Chen, Han Guan

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Prospects of Using Microbiota Correction Methods in the Treatment of Inflammatory Bowel Disease by A. I. Akinshina, D. V. Smirnova, A. V. Zagainova, V. V. Makarov, S. M. Yudin

“…Inflammatory bowel disease (IBD) is an umbrella term used to describe a group of chronic diseases of unknown aetiology. In the past, bacteriological methods based on the isolation of a pure bacterial culture were used to determine the microbiota composition. …”
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Prospects for mineral biofortification of wheat: classical breeding and agronomy by I. N. Leonova, E. V. Ageeva, V. K. Shumny

“…Low intake of micro- and macroelements and vitamins in food negatively affects the health of more than two billion people around the world provoking chronic diseases. For the majority of the world’s population, these are soft and durum wheats that provide beneficial nutrients, however their modern high-yielding varieties have a significantly depleted grain mineral composition that have reduced mineral intake through food. …”
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Inflammatory Markers Are Positively Associated with Serum trans-Fatty Acids in an Adult American Population by Mohsen Mazidi, Hong-kai Gao, Andre Pascal Kengne

“…Because serum TFAs concentrations are affected by dietary TFA intake, these data suggest a possible contribution of TFAs intake modulation in the prevention of inflammation-related chronic diseases.…”
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Reinforcing Mothers’ Nutritional Knowledge to Combat the Spread of Non-Communicable Diseases: Food-Based Dietary Guidelines by Yolisa Christina Majija

“…Increasing knowledge about nutrition through education and interventions may help reduce the risk of chronic diseases and enhance overall health.…”
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Validation of the Arabic Version of Medication Regimen Complexity Index Among Older Patients - Validation of the “MRCI-Arabic” by Nilay Aksoy, Nur Ozturk, Betul Okuyan, Mesut Sancar

“…There was a strong and positive correlation between the total MRCI-Arabic score and the number of medications (r = 0.830; p < 0.001), the number of chronic diseases (r = 0.641; p < 0.001). Conclusion: The Arabic validation of the MRCI is a validated tool that can be used by native Arabic-speaking healthcare professionals to determine the complexity of their patients’ medication regimens. …”
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E-cigarettes are not associated with post-acute COVID-19 syndrome among US adults by Shahryar Rajai Firouzabadi, Ida Mohammadi, Mohammadreza Alinejadfard, Arman Shafiee

“…It analyzed e-cigarette use (never, former, current) and controlled for key covariates such as age, gender, BMI, smoking, and chronic diseases. The results showed that female gender, obesity, current smoking, and a history of depression, asthma, and chronic obstructive pulmonary disease (COPD) were significantly associated with higher odds of PCS. …”
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Characterization of Positive and Suspected COVID-19 Cases with Comorbidities by Yoenny Peña García, Annia Suárez Padilla, Niuva Milagro Arruebarrena Blanco

“…<strong>Background:</strong> factors associated with the severity and worse prognosis in SARS-CoV-2 infection have been described, such as age, the presence of chronic diseases such as diabetes, arterial hypertension and those that compromise the immune system. …”
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The association between physical activity, low-grade inflammation, and labour market attachment among people with multimorbidity: A cross-sectional study from the Lolland-Falster H... by Vivian Rueskov Poulsen, Linda Kjær Fischer, Mette Aadahl, Ole Steen Mortensen, Søren T Skou, Lars Bo Jørgensen, Randi Jepsen, Anne Møller, Therese Lockenwitz Petersen, Jan Christian Brønd, Lars Tang, Mette Korshøj

“…Conclusion PA recommendations should be developed with attention to people with chronic diseases, who may experience barriers to reach PA at high intensities. …”
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Result of Surgery to Patients with Brain Tumor in Cienfuegos by Jorge Luis Acevedo Cardoso, Samuel Sánchez Sánchez, Yoniel Suárez Guerrero, Tamara García Alfonso de Armas, Wendy Gómez Menéndez

“…The variables studied were: age, sex, history of chronic diseases, history of neoplasia of another location, onset syndrome, anatomical location according to the imaging study performed, degree of macroscopic cytoreduction, Karnofsky scale, tumor type, postoperative complications and survival after six months of surgery. …”
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Insidensi Bayi Berat Lahir Rendah pada Spektrum Plasenta Akreta di Rumah Sakit Dr Hasan Sadikin Bandung by Yuktiana Kharisma, Hasrayati Agustina, Sri Suryanti, Birgitta Maria Dewayani, Bethy Suryawati Hernowo

“…Low birth weight (LBW) babies are closely related to infant morbidity, stunted growth and cognitive development, and chronic diseases. Placenta accreta spectrum (PAS) is a condition that complicates pregnancy and is closely related to low birth weight. …”
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Alcohol in Daily Products: Health Risks, Cultural Considerations, and Economic Impacts by Herdiana Y

“…The World Health Organization has determined that no amount of alcohol consumption can be considered entirely safe, as ethanol’s health impacts include contributions to chronic diseases, neurotoxicity, and potential carcinogenic effects. …”
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Association between bronchial asthma severity, control level and life quality in children by Alexander Torres Molina

“…<p><strong>Foundation</strong>: bronchial asthma is one of the most prevalent chronic diseases in childhood. The guidelines for diagnosis and treatment are governed by severity, level of control and quality of life, however, there is no evidence that demonstrates its statistical association.…”
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