Transendothelial migration of the Lyme disease spirochete involves spirochete internalization as an intermediate step through a transcellular pathway that involves Cdc42 and Rac1 by Daiana Alvarez-Olmedo, Claire Kamaliddin, Theodore B. Verhey, May Ho, Rebekah De Vinney, George Chaconas

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Cerebrovascular Diseases and Risk Factors: a Strategy of Primary Prevention by Miguel Angel Buergo Zuaznábar, Rubén Bembibre Taboada

“…Cerebrovascular diseases constitute a health problem worldwide and have the tendency to grow up. Chronic diseases sometimes are considered transmissible diseases at a level of risk factors. …”
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Post Varicella Necrotising Fasciitis Afflicting Upper Limb in Young Child: A Rare Case Report by Swarup Prabhu, Ayjaz Hussain, Tarun Gupta

“…Risk factors include immunosuppression, type 2 diabetes mellitus, chronic diseases like cirrhosis of liver and chronic kidney disease, malignancies, intravenous drug use, obesity, and age more than 60 years. …”
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Clinical Aspects of Trace Elements: Zinc in Human Nutrition – Zinc Deficiency and Toxicity by Michelle M Pluhator, Alan Br Thomson, Richard N Fedorak

“…Conditioned deficiencies have been reported to result from malabsorption syndromes, acrodermatitis enteropathica, alcoholism, gastrointestinal disease, thermal injury, chronic diseases (eg, diabetes, sickle cell anemia), and in total parenteral nutrition therapy. …”
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The Potential of Food Protein-Derived Bioactive Peptides against Chronic Intestinal Inflammation by Wanying Zhu, Liying Ren, Li Zhang, Qinqin Qiao, Muhammad Zahid Farooq, Qingbiao Xu

“…Inflammation can cause various chronic diseases like inflammatory bowel diseases. Various food protein-derived bioactive peptides (BAPs) with anti-inflammatory activity have the potential to manage these diseases. …”
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Antifibrotic Activity of Acylated and Unacylated Ghrelin by Elia Angelino, Simone Reano, Michele Ferrara, Emanuela Agosti, Andrea Graziani, Nicoletta Filigheddu

“…Fibrosis can affect almost all tissues and organs, it often represents the terminal stage of chronic diseases, and it is regarded as a major health issue for which efficient therapies are needed. …”
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Molecular Mechanisms Regulating Hepcidin Revealed by Hepcidin Disorders by Clara Camaschella, Laura Silvestri

“…Alterations of the same systems are also found in acquired disorders, such as iron-loading anemias characterized by ineffective erythropoiesis and anemia of chronic diseases (ACD) associated with common inflammatory conditions. …”
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Białka roślinne i ich funkcjonalne działania by Grażyna Nowicka

“…Diet containing such types of food may promote better health and play an important role in disease prevention by reducing the risk of certain chronic diseases. Vegetable proteins, especially legume proteins, have been recognized as factors influencing lipid metabolism. …”
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The Perceived Social Stigma of People with Epilepsy with regard to the Question of Employability by Jéssica Lopes de Souza, Aline Scardoeli Faiola, Carmen Silvia Molleis Galego Miziara, Maria Luiza Giraldes de Manreza

“…A structured questionnaire was given to two groups of people with chronic diseases: those with epilepsy (study group) and those with heart disease (control group). …”
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Synaptic Structure and Function in the Mouse Somatosensory Cortex during Chronic Pain: In Vivo Two-Photon Imaging by Sun Kwang Kim, Kei Eto, Junichi Nabekura

“…These updated in vivo approaches are just beginning to be used for the study of pathophysiological mechanisms of chronic diseases. In this paper, we introduce recent in vivo two-photon imaging studies demonstrating how plastic changes in synaptic structure and function of the mouse somatosensory cortex, following peripheral injury, contribute to chronic pain conditions, like neuropathic and inflammatory pain.…”
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A mixed methods protocol to investigate medication adherence in patients with rheumatoid arthritis of White British and South Asian origin by Karim Raza, Peter Nightingale, Karen Shaw, Rob Horne, Kanta Kumar, Sheila Greenfield, Paramjit Gill

“…Background Low adherence to medicines is an important issue as up to 40% of patients with chronic diseases do not take their medications as prescribed. …”
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Food-Based Dietary Guidelines for the Arab Gulf Countries by Abdulrahman O. Musaiger, Hamed R. Takruri, Abdelmonem S. Hassan, Hamza Abu-Tarboush

“…The FBDG can be a useful tool in educating the public in healthy eating and prevention of diet-related chronic diseases.…”
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The Role of Toll-Like Receptor 4 in Infectious and Noninfectious Inflammation by Monica Molteni, Sabrina Gemma, Carlo Rossetti

“…TLR4-mediated inflammation, triggered by exogenous or endogenous ligands, is also involved in several acute and chronic diseases, having a pivotal role as amplifier of the inflammatory response. …”
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Intestinal Immunomodulatory Cells (T Lymphocytes): A Bridge between Gut Microbiota and Diabetes by Qingwei Li, Zezheng Gao, Han Wang, Haoran Wu, Yanwen Liu, Yingying Yang, Lin Han, Xinmiao Wang, Linhua Zhao, Xiaolin Tong

“…Diabetes mellitus (DM) is one of the most familiar chronic diseases threatening human health. Recent studies have shown that the development of diabetes is closely related to an imbalance of the gut microbiota. …”
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Recent progress of polymeric microneedle-assisted long-acting transdermal drug delivery by Fanda Meng, Xinyu Qiao, Chenglong Xin, Xiaoli Ju, Meilin He

“…Long-acting polymeric MNs can reduce administration frequency to improve patient compliance and therapeutic outcomes, especially in the management of chronic diseases. In addition, long-acting MNs could avoid gastrointestinal reactions and reduce side effects, which has potential value for clinical application. …”
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Enhancing Exercise Responsiveness across Prediabetes Phenotypes by Targeting Insulin Sensitivity with Nutrition by Julian M. Gaitan, Arthur Weltman, Steven K. Malin

“…Exercise is a cornerstone therapy for chronic diseases related to multiorgan insulin resistance. …”
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Risk factors in pediatric asthmatic patients. Cases and control studies. by Rafael Alejandro Gómez Baute, Yaney Gonzalez Iglesias

“…<strong>Background: </strong>Asthma constitutes the first disease among chronic diseases in children. The morbid-mortality promoted to continue being elevated in spite of the new therapies. …”
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Metallic and Microbial Contaminants in Drinking Water of Cankiri, Turkey by Emrah Caylak, Mustafa Tokar

“…These are undesirable substances dangerous to human health and cause chronic diseases and various cancers. Coliform bacteria are a commonly used bacterial indicator of sanitary quality of water. …”
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Efficacy of esomeprazole at treatment of patients with gastroesophageal reflux disease by Yu. V. Yevsyutina

“…GERD is one of the most widespread chronic diseases. Proton pump inhibitors (PPI) are the basic treatment of GERD that promote symptom relief (both esophageal, and extraesophageal) as well as the healing of esophageal mucosa lesions, prevent development of relapses and complications of reflux esophagitis. …”
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Treatment of neuro-invasive listeriosis: an overview by P. Gudeikaitė, J. Valaikienė, R. Mameniškienė

“…The most at-risk populations are pregnant women, neonates, people over 65 years of age, and patients with chronic diseases or using immunosuppressive drugs. In case of suspected acute meningitis, encephalitis or meningoencephalitis in these individuals, it must be considered that the pathogen can be Listeria monocytogenes, which is resistant to the therapy of cephalosporins. …”
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