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Computer modeling of the peculiarities in the interaction of IL-1 with its receptors in schizophrenia
Published 2024-05-01“…The NCBI Protein service was employed to search for and analyze the position of the identified polymorphisms on the chromosome. Structures for modeling were extracted from the Protein Data Bank database. …”
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1262
Resistance of synthetic hexaploid wheat to the leaf rust pathogen
Published 2021-10-01“…One of the promising sources for enrichment of the common wheat (Triticum aestivum L.) gene pool with new alleles is synthetic hexaploid wheat (SHW), or allopolyploids from crossing tetraploid wheats (2n = 4x = 28, BBAA) with accessions of Aegilops tauschii Coss. (2n = 2x = 14, DD), and subsequent doubling of the chromosome number in the hybrids. Objectives of the study were to evaluate the SHW accessions from the VIR collection for resistance to Puccinia triticina Erikss. populations collected in Russia; genotype the accessions; and summarize information from the published sources concerning the resistance of the studied accessions to other harmful diseases and pests.Materials and methods. …”
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1263
Knockdown of PTEN promotes colon cancer progression and induces M2 macrophage polarization in the colon cancer cell environment
Published 2023-07-01“…Objective: This article aims to study the effect of phosphate and tension homolog deleted on chromosome ten (PTEN) knockdown on colon cancer progression and macrophage polarization in the cancer environment. …”
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1264
Technological properties of grain and flour in bread wheat (<i>Triticum aestivum</i> L.) genotypes carrying two loci that determine the endosperm structure
Published 2021-04-01“…The end-use of the bread wheat grain depends on the endosperm properties determined by the alleles of the Pina and Pinb genes at the Ha locus on chromosome 5D. The mealy (soft) endosperm is generated by the biosynthesis of puroindolines – complete proteins encoded by these genes. …”
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1265
Like milk on the stove: Healthcare professionals navigating uncertainty when caring for families with 22q11DS.
Published 2025-01-01“…<h4>Introduction</h4>22q11 deletion syndrome (22q11DS) results from a microdeletion on chromosome 22 and is the most common microdeletion disorder in humans, affecting 1 in 2148 live births. …”
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1266
Integrated analysis of single-cell and bulk-RNA sequencing for the cellular senescence in prognosis of lung adenocarcinoma
Published 2025-01-01“…Telomerase, which maintains telomere length and chromosomal integrity, enables cancer cells to avoid replicative senescence. …”
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1267
Impact of Interleukin-10 Promoter Region Polymorphisms on Recurrent Miscarriage: A Case–Control Approach
Published 2023-04-01“…The aetiological basis of RM has been traced to chromosomal, anatomic, hormonal and immunologic factors while half of the cases remain idiopathic. …”
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1268
The Muscadine Grape (Vitis rotundifolia Michx)
Published 2020-11-01“…Euvitis and Muscadania have somatic chromosome numbers of 38 and 40, respectively. Vines do best in deep, fertile soils, and they can often be found in beside river beds. …”
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1269
Identification and characterization of CONSTANS-like (COL) gene family in upland cotton (Gossypium hirsutum L.).
Published 2017-01-01“…In this study, we identified 42 COL homologs (GhCOLs) in the G. hirsutum genome, and many of them were previously unreported. We studied their chromosome distribution, phylogenetic relationships, and structures of genes and proteins. …”
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1270
Nuclear DNA Content and Chromatin Pattern of Rat Rhabdomyosarcoma Cell Sublines with Different Metastatic Potentials
Published 2000-01-01“…The nuclear DNA content, the chromosome numbers, the cell sublines doubling times, and the distribution of cells within the cell cycle appear unrelated with this score. …”
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1271
CRISPR/Cas9, a universal tool for genomic engineering
Published 2016-09-01“…A programmable nature of CRISPR/Cas9 facilitates the creation of transgenic organisms through sitespecific gene mutations, knock-ins or large chromosomal rearrangements (deletions, inversions and duplications). …”
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1272
Genome assembly and population analysis of tetraploid marama bean reveal two distinct genome types
Published 2025-01-01“…Using 21.5 Gb of PacBio HiFi data, the genome was assembled with two assemblers, HiCanu and Hifiasm, followed by scaffolding with Omni-C data from Dovetail Genomics (Cantata Bio) using HiRise, resulting in a 558.78 Mb assembly with near chromosome-level continuity (N50 = 22.68 Mb, L50 = 8). …”
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1273
The highly prolific phenotype of Lacaune sheep is associated with an ectopic expression of the B4GALNT2 gene within the ovary.
Published 2013-01-01“…Our previous work localized FecL on sheep chromosome 11 within a locus of 1.1 Mb encompassing 20 genes. …”
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1274
Marek's disease virus-1 unique gene LORF1 is involved in viral replication and MDV-1/Md5-induced atrophy of the bursa of Fabricius.
Published 2025-02-01“…To this end, an infectious bacterial artificial chromosome (BAC) harboring the complete genome of the MDV-1 very virulent strain Md5 was generated, and the rescued rMd5 maintained biological properties similar to the parental virus both in vitro and in vivo. …”
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Analysis of prenatal diagnosis and pregnancy outcomes for rare autosomal trisomies detected by non-invasive prenatal testing in 33,079 cases
Published 2025-02-01“…Conclusion Prenatal diagnosis for high-risk rare autosomal trisomies typically reveals a normal karyotype with no detectable chromosomal abnormalities, and most cases can achieve full-term pregnancy outcomes. …”
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Stan biologiczny populacji ludzkich a przemiany środowiska społeczno-ekonomicznego
Published 2006-12-01“…Variability originates from point mutations and chromosomal aberrations occurring during transmission of genetic material from generation to generation and through activation, or deactivation, of genes that alters their expression. …”
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1278
Genome-Wide Association Study towards Genomic Predictive Power for High Production and Quality of Milk in American Alpine Goats
Published 2020-01-01“…These candidate genes segregated as separate novel SNPs and were identified as statistically significant regions for genome and chromosome level trait associations. Candidate genes associated differently for each of the following phenotypic traits: test day milk yield (13,469 candidate genes), test day protein yield (25,690 candidate genes), test day fat yield (25,690 candidate genes), percentage protein (25,690 candidate genes), percentage fat (25,690 candidate genes), and percentage lactose content (25,690 candidate genes). …”
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1279
Cluster Optimization in Mobile Ad Hoc Networks Based on Memetic Algorithm: memeHoc
Published 2020-01-01“…New individuals are generated using the crossover mechanism on the chromosome once the two parents have been selected. …”
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1280
GENETICS OF THE TRAITS DEFINING THE QUALITY OF RUSSIAN RICE VARIETIES
Published 2018-03-01“…Polymorphism of domestic varieties of rice with contrasting quality traits such as “weight of 1000 grains”, “translucency”, “husk content”, “the maintenance of the whole kernel in a croup” was studied with use of the SSR markers to reveal chromosomal regions associated with the division of Russian rice varieties into groups based on the traits being studied. …”
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