Primary Synovial Sarcoma of Kidney: A Rare Differential Diagnosis of Renomegaly by Gaurang Modi, Irappa Madabhavi, Harsha Panchal, Asha Anand, Apurva Patel, Sonia Parikh, Swaroop Revannasiddaiah

“…Though they have characteristic histology and immunohistochemistry (IHC) due to rarity of incidence it is difficult to diagnose them. Sometimes chromosomal rearrangement studies are required to confirm the diagnosis. …”
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Molecular Pathogenesis of MALT Lymphoma by Katharina Troppan, Kerstin Wenzl, Peter Neumeister, Alexander Deutsch

“…Interestingly, at least 3 different, apparently site-specific, chromosomal translocations and missense and frameshift mutations, all pathway-related genes affecting the NF-κB signal, have been implicated in the development and progression of MALT lymphoma. …”
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Genome-Wide Association Study of Coronary Artery Disease by Naomi Ogawa, Yasushi Imai, Hiroyuki Morita, Ryozo Nagai

“…In 2007, three chip-based GWAS simultaneously revealed the significant association between common variants on chromosome 9p21 and CAD. This association was replicated among other ethnic groups and also in a meta-analysis. …”
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Trypanosoma cruzi Infection in Genetically Selected Mouse Lines: Genetic Linkage with Quantitative Trait Locus Controlling Antibody Response by Francisca Vorraro, Wafa H. K. Cabrera, Orlando G. Ribeiro, José Ricardo Jensen, Marcelo De Franco, Olga M. Ibañez, Nancy Starobinas

“…An Ab production QTL marker mapping to mouse chromosome 1 (34.8 cM) significantly cosegregated with survival after acute T. cruzi infections, indicating that this region also harbors genes whose alleles modulate resistance to acute T. cruzi infection.…”
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Fetal intracranial hemorrhage in second trimester: An ominous finding even after a normal array by Yu-Hong Long, Si-Qi Wu, Xin Wang, Li-Ping Wu, Yi-Min Xiong, Xin Yang, Feng-Xiang Wei

“…All tests such as karyotyping, chromosomal microarray analysis (CMA), and PCR-cytomegalovirus detection of amniotic fluid, returned negative results. …”
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A dual role of Cohesin in DNA DSB repair by Michael Fedkenheuer, Yafang Shang, Seolkyoung Jung, Kevin Fedkenheuer, Solji Park, Davide Mazza, Robin Sebastian, Hiroyuki Nagashima, Dali Zong, Hua Tan, Sushil Kumar Jaiswal, Haiqing Fu, Anthony Cruz, Supriya V. Vartak, Jan Wisniewski, Vittorio Sartorelli, John J. O’Shea, Laura Elnitski, Andre Nussenzweig, Mirit I. Aladjem, Fei-Long Meng, Rafael Casellas

“…Cohesin, a multi-subunit protein complex, plays a crucial role in both chromosome organization and DNA repair by creating architectural loops through chromatin extrusion. …”
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A Toxicological Evaluation of a Standardized Hydrogenated Extract of Curcumin (CuroWhite™) by Alastimmanahalli Narasimhiah Ravikumar, Joby Jacob, Sreeraj Gopi, Tumkur Subbarao Jagannath

“…The test item was not mutagenic in the bacterial reverse mutation test or in vitro mammalian chromosomal aberration test, and no in vivo genotoxic activity was observed in rat bone marrow in the micronucleus test. …”
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The History of Methicillin-Resistant Staphylococcus aureus in Brazil by Mariana Moreira Andrade, Wilson Barros Luiz, Rayane da Silva Oliveira Souza, Jaime Henrique Amorim

“…In this review, we present the main events which compose the history of MRSA in Brazil, including numbers and locations of isolation, as well as types of staphylococcal cassette chromosome mec (SCCmec) found in the Brazilian territory.…”
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Polymorphisms of Homologous Recombination RAD51, RAD51B, XRCC2, and XRCC3 Genes and the Risk of Prostate Cancer by Maria Nowacka-Zawisza, Ewelina Wiśnik, Andrzej Wasilewski, Milena Skowrońska, Ewa Forma, Magdalena Bryś, Waldemar Różański, Wanda M. Krajewska

“…Homologous recombination repair (HRR) plays a critical role in maintaining chromosomal integrity and protecting against carcinogenic factors. …”
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Papillion-Lefèvre Syndrome: Periodontists’ Perspective by Sunil Kumar Biraggari, K. Krishna Mohana Reddy, J. Sudhakar, Shiva Shankar Bugude, Rajesh Nichenametla, Mazher Ahmed Hakeem, Swati Reddy Tiyyagura

“…Genetic studies have identified a mutation in the major gene locus of chromosome 11q14 with loss of function. Cathepsin C gene is to be responsible for Papillion-Lefèvre Syndrome. …”
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HbS-Sicilian (δβ)0-Thalassemia: A Rare Variant of Sickle Cell by Grace Onimoe, Genine Smarzo

“…Sickle cell disease (SCD) is caused by a mutation in the sixth codon of the β-globin gene on chromosome 11, which leads to a single amino acid substitution (glutamine to valine). …”
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Repeated Long-Term DT Application in the DEREG Mouse Induces a Neutralizing Anti-DT Antibody Response by Junhua Wang, Myriam Siffert, Markus Spiliotis, Bruno Gottstein

“…Genetic tools exploiting the foxp3 locus including bacterial artificial chromosome- (BAC-) transgenic DEpletion of REGulatory T cells (DEREG) mice have provided essential information on Treg biology and the potential therapeutic modulation of tolerance. …”
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PRESERVATION OF THE GENE POOL OF PLANTS UNDER IN PERMAFROST CONDITIONS: STATE, ADVANTAGES, AND PROSPECTS by B. M. Kershengolts, I. F. Zhimulev, N. P. Goncharov, R. V. Chzhan, G. V. Filippova, A. A. Shein, I. A. Prokopiev

“…The observed number of chromosomal aberrations in root meristem cells did not increase, except P. sativum cv. …”
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Plant Regeneration and Cellular Behaviour Studies in Celosia cristata Grown In Vivo and In Vitro by Rosna Mat Taha, Sharifah Nurashikin Wafa

“…It was observed that Mitotic Index (MI), mean chromosome numbers, and mean nuclear to cell area ratio of in vitro root meristem cells were slightly higher compared to in vivo values. …”
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Comprehensive genome annotation of Trilocha varians, a new model species of Lepidopteran insects by Jung Lee, Toshiaki Fujimoto, Katsushi Yamaguchi, Shuji Shigenobu, Ken Sahara, Toru Shimada

“…To facilitate further use of T. varians, we developed genome annotation information on the chromosome-scale assembly of T. varians previously published by our group. 9 RNA-seq datasets and 2 Iso-seq datasets were submitted for transcriptome-based gene prediction. …”
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Unravelling genomic drivers of speciation in Musa through genome assemblies of wild banana ancestors by Guillaume Martin, Benjamin Istace, Franc-Christophe Baurens, Caroline Belser, Catherine Hervouet, Karine Labadie, Corinne Cruaud, Benjamin Noel, Chantal Guiougou, Frederic Salmon, Joël Mahadeo, Fajarudin Ahmad, Hugo A. Volkaert, Gaëtan Droc, Mathieu Rouard, Julie Sardos, Patrick Wincker, Nabila Yahiaoui, Jean-Marc Aury, Angélique D’Hont

“…Comparative and phylogenetic analyses reveal an ongoing speciation process within Musa, characterised by large chromosome rearrangements and centromere differentiation through the integration of different types of repeated sequences, including rDNA tandem repeats. …”
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Meiosis-specific stable binding of augmin to acentrosomal spindle poles promotes biased microtubule assembly in oocytes. by Nathalie Colombié, A Agata Głuszek, Ana M Meireles, Hiroyuki Ohkura

“…The level of Augmin accumulated at spindle poles is well correlated with the degree of chromosome congression. Fluorescence recovery after photobleaching shows that Augmin stably associates with the polar regions of the spindle in oocytes, unlike in mitotic cells where it transiently and uniformly associates with the metaphase spindle. …”
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Chronic Myeloid Leukemia Relapsing 25 Years after Allogenic Stem Cell Transplantation by Håkon Reikvam, Jørn Skavland, Stein-Erik Gullaksen, Randi Hovland, Tobias Gedde-Dahl, Øystein Bruserud, Bjørn Tore Gjertsen

“…Chronic myeloid leukemia (CML) is a myeloproliferative disorder in which neoplastic cells exhibit the Philadelphia chromosome and the related oncoprotein BCR-ABL1. Allogeneic stem cell transplantation (allo-SCT) was considered the first-line treatment for CML, before the introduction of tyrosine kinase inhibitors (TKIs). …”
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The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases by Faris Azzouni, Alejandro Godoy, Yun Li, James Mohler

“…This review describes the basic biochemical properties, functions, tissue distribution, chromosomal location, and clinical significance of the 5 alpha-reductase isozyme family.…”
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Sex Differences Associated with Primary Biliary Cirrhosis by Daniel S. Smyk, Eirini I. Rigopoulou, Albert Pares, Charalambos Billinis, Andrew K. Burroughs, Luigi Muratori, Pietro Invernizzi, Dimitrios P. Bogdanos

“…There does not appear to be any histological, serological, or biochemical differences between male and female PBC, although the symptomatology may differ, with males being at higher risk of life-threatening complications such as gastrointestinal bleeding and hepatoma. Studies on X chromosome and sex hormones are of interest when studying the low preponderance of PBC in males; however, these studies are far from conclusive. …”
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