Molecular cloning of EZH2 oncogene in chronic myeloid leukemia and therapeutic prospects by Juliana Costa Gaspar, Lucas Santos de Santana, Camila Menezes Freire de Souza, Marcos Montani Caseiro, Rosane Rezende de Souza Giuliani, Cleide Barbieri de Souza

“…Chronic myeloid leukemia (CML) is a myeloproliferative neoplasia, caused in 95 % of the cases by a cytogenetic abnormality characterized by the reciprocal translocation between chromosomes 9 and 22 t(9; 22) (q34; q11), resulting in Philadelphia chromosome (Ph).Considering that CML cure is only possible with a successful bone marrow transplantation and that there are resistance cases to the tyrosine kinase inhibitor Imatinib Mesylate, prescribed in first line drug treatment; it is important to know in detail the genes and proteins that are possibly altered in CML, favoring effective therapeutic strategies, optimized diagnosis and minimal residual disease detection. …”
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Expression Profiling of Long Noncoding RNA Splice Variants in Human Microvascular Endothelial Cells: Lipopolysaccharide Effects In Vitro by Imran H. Chowdhury, Hema P. Narra, Abha Sahni, Kamil Khanipov, Casey L. C. Schroeder, Jignesh Patel, Yuriy Fofanov, Sanjeev K. Sahni

“…A majority of LPS-induced lncRNAs are multiexonic and distributed across the genome as evidenced by their presence on all chromosomes. Present among these are a total of 44 lncRNAs with known regulatory functions, of which 41 multiexonic lncRNAs have multiple splice variants. …”
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Systematic and Cell Type-Specific Telomere Length Changes in Subsets of Lymphocytes by Jue Lin, Joshua Cheon, Rashida Brown, Michael Coccia, Eli Puterman, Kirstin Aschbacher, Elizabeth Sinclair, Elissa Epel, Elizabeth H. Blackburn

“…Telomeres, the protective DNA-protein complexes at the ends of linear chromosomes, are important for genome stability. Leukocyte or peripheral blood mononuclear cell (PBMC) telomere length is a potential biomarker for human aging that integrates genetic, environmental, and lifestyle factors and is associated with mortality and risks for major diseases. …”
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Variability of morphological features and nuclear DNA content in haploids and doubled haploids of androgenic callus lines of rice (<I>Oryza sativa</I> L.) by M. V. Ilyushko, M. V. Skaptsov, M. V. Romashova

“…Aneuhaploid evolution explains the intraspecific variability of chromosome numbers among plant species with low ploidy. …”
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Haploid biotechnology as a tool for creating a selection material for sugar beets by E. O. Kolesnikova, E. I. Donskikh, R. V. Berdnikov

“…There are several methods for obtaining forms with a single set of chromosomes. For sugar beets, the use of gynogenesis turned out to be expedient, since in this case the other methods turned out to be ineffective in the mass production of haploids. …”
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EXAMINATION OF ADAPTIVE AND AGRONOMIC CHARACTERS IN LINES OF COMMON WHEAT OMSKAYA 37 BEARING TRANSLOCATIONS 1RS.1BL AND 7DL-7Ai by I. A. Belan, L. P. Rosseeva, V. M. Rosseev, E. D. Badaeva, Y. I. Zelenskiy, N. P. Blokhina, S. S. Shepelev, L. A. Pershina

“…It is shown that these lines, in addition to wheat-rye translocation 1RS.1BL possess wheat-wheatgrass translocation 7DL-7Ai, where a segment of chromosome 7Ai of Agropyron elongatum (= Thinopyrum elongatum ; = Thinopyrum ponticum) is translocated to the long arm of wheat chromosome 7D. …”
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Genome-wide association scan and candidate gene analysis for seed coat color in sesame (Sesamum indicum L.) by Mohammed Elsafy, Wafa Badawi, Ahmed Ibrahim, Elamin Hafiz Baillo, Prabin Bajgain, Tilal Sayed Abdelhalim, Mahbubjon Rahmatov

“…GWAS identified significant SNPs associated with seed coat color traits, revealing key genomic regions on chromosomes 3, 6, 9, 12, and 13. Candidate gene analysis highlighted several genes, including DOF zinc finger proteins and WRKY transcription factors, which may play essential roles in pigment biosynthesis pathways. …”
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New genetic resources in wheat breeding for an increased grain protein content by O. P. Mitrofanova, A. G. Khakimova

“…Moreover, Gpc-A1, Gpc-D1, and Gpc-2 wheat genes have been found in chromosomes 6A, 6D and homeologous group 2, respectively. …”
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Detection of CRISPR cassettes and cas genes in the Arabidopsis thaliana genome by Yu. M. Konstantinov, I. S. Petrushin

“…Both cas genes and numerous CRISPR cassettes were found on all the five chromosomes in the nuclear genome of the Col-0 ecotype. …”
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Change of salt tolerance in common wheat after introgression of genetic material from Aegilops speltoides and Triticum timopheevii by R. S. Yudina, I. N. Leonova, E. A. Salina, E. K. Khlestkina

“…Different fragments of T. timo- pheevii genome had different effects: introgression into the chromosome 2A increased salt tolerance, whereas introgression into chromosome 5B reduced it significantly. …”
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MAPPING OF QTLS DETERMINING THE EXPRESSION OF AGRONOMICALLY AND ECONOMICALLY VALUABLE FEATURES IN SPRING WHEAT (TRITICUM AESTIVUM L.) GROWN IN ENVIRONMENTALLY DIFFERENT RUSSIA REGI... by Yu. V. Chesnokov, N. V. Pochepnya, L. V. Kozlenko, M. N. Sitnikov, O. P. Mitrofanova, V. V. Syukov, D. V. Kochetkov, U. Lovasser, A. Börner

“…QTLs for traits studied, mapped on 21 chromosomes, manifested themselves under contrasting environmental conditions with varying degrees of reliability. …”
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Influence of breed and environment on leukocyte telomere length in cattle by N. S. Yudin, A. V. Igoshin, G. A. Romashov, A. A. Martynov, D. M. Larkin

“…Telomeres are elements found at the ends of chromosomes, consisting of repetitive DNA sequences, several thousand base pairs in length, coupled with nucleoprotein complexes. …”
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Malignant Phyllodes Tumor and Acute Megakaryoblastic Leukemia Sharing a Common Clonal Origin by Yngvar Fløisand, Klaus Beiske, Geir Erland Tjønnfjord, Dag Heldal, Bodil Bjerkehagen, Mona-Elisabeth Revheim, Sverre Heim, Øyvind Sverre Bruland, Kirsten Sundby Hall, Anne Tierens, Jan Delabie

“…We treated a young female patient with a malignant phyllodes tumor followed by an acute megakaryoblastic leukemia and found several of the same marker chromosomes by karyotype analysis of cells from both the tumor and the leukemia implying a common clonal origin of the two. …”
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Diversification and recurrent adaptation of the synaptonemal complex in Drosophila. by Rana Zakerzade, Ching-Ho Chang, Kamalakar Chatla, Ananya Krishnapura, Samuel P Appiah, Jacki Zhang, Robert L Unckless, Justin P Blumenstiel, Doris Bachtrog, Kevin H-C Wei

“…The synaptonemal complex (SC) is a protein-rich structure essential for meiotic recombination and faithful chromosome segregation. Acting like a zipper to paired homologous chromosomes during early prophase I, the complex is a symmetrical structure where central elements are connected on two sides by the transverse filaments to the chromatin-anchoring lateral elements. …”
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Molecular genetic bases of seed resistance to oxidative stress during storage by N. A. Shvachko, E. K. Khlestkina

“…QTLs associated with barley seed longevity were identified on chromosomes 2H, 5H and 7H. In the QTL regions studied, the Zeo1, Ale, nud, nadp-me, and HvGR genes were identified. …”
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Genome-wide maps of highly-similar intrachromosomal repeats that can mediate ectopic recombination in three human genome assemblies by Luis Fernandez-Luna, Carlos Aguilar-Perez, Christopher M. Grochowski, Michele G. Mehaffey, Claudia M.B. Carvalho, Claudia Gonzaga-Jauregui

“…Summary: Repeated sequences spread throughout the genome play important roles in shaping the structure of chromosomes and facilitating the generation of new genomic variation through structural rearrangements. …”
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Silica-exposed patients with silicosis show shorter telomeres than do unexposed individuals: a pilot study in a population in southeastern Brazil by Marcos César Santos de Castro, Lucas de Carvalho Costa, Kaio Cezar Rodrigues Salum, Hermano Albuquerque de Castro, Patrícia Canto Ribeiro, Walter Costa, Angela Santos Ferreira Nani, Fabiana Barzotto Kohlrausch

“…This oxidative stress affects telomeres, which are short tandem DNA repeats that cap the end of linear chromosomes. We aimed to determine whether telomere length (TL) correlates with silicosis or severity of silicosis in silica-exposed workers in Brazil. …”
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Analysis of the transcriptional activity of model piggyBac transgenes stably integrated into different loci of the genome of CHO cells in the absence of selection pressure by L. A. Yarinich, A. A. Ogienko, A. V. Pindyurin, E. S. Omelina

“…In total, ~640 transgenes more or less evenly distributed across all chromosomes of CHO cells were characterized. More than half of the transgenes were completely silent. …”
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Cosmetic Outcome of Feminizing Genitoplasty in DSD (Disorders of Sex Development) by ِِAsmaa Gaber Rizk, Hamdy Muhammad Hussein, Sara Mohammed Habib Abdel-Hamied, Nezar Abdelraouf Abo Halawa

“…Background: Disorders of sex development (DSD) include a diverse array of congenital disorders characterized by the abnormal growth of anatomical sex, chromosomes, gonads, & the brain, all of which are essential to the process of sexual differentiation. …”
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Genome-wide identification of high-affinity nitrate transporter 2 (NRT2) gene family under phytohormones and abiotic stresses in alfalfa (Medicago sativa) by Yanyan Luo, Lili Nan

“…They were named MsNRT2.1-2.3 based on their chromosomal location. The phylogenetic tree revealed that NRT2 proteins were categorized into two main subgroups, which were further confirmed by their gene structure and conserved motifs. …”
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